Publications per year
Publications per year
Personal profile
Profile
Gærgenetik og reparation af DNA skader
Ud over at være centerleder for CMB forsker Uffe Mortensen i genreparationer og mekanismerne bag genetisk ustabilitet. Typisk bruger han mikroorgansimer som modelsystemer til at forstå disse komplekse processer med henblik på at kunne udvikle stabile produktionsstammer og til at forstå de molekylære mekanismer, der leder til cancer. Et andet mål i hans forskning er at finde metoder til at manipulere genomer. I mikroorganismer kan dette udnyttes til at skræddersy en organisme til effektivit at lave et interessant produkt, fx en metabolit, der normalt bliver produceret i en plante, eller til at lave definerede mutant biblioteker i en given stamme med henblik på en komplet genetisk kortlægning af en given proces. I fremtiden vil videreudvikling af sådanne metoder kunne bruges medicinsk som genterapi.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Publications
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A Mad7 System for Genetic Engineering of Filamentous Fungi
Vanegas, K. G., Rendsvig, J. K. H., Jarczynska, Z. D., Cortes, M. V. D. C. B., van Esch, A. P., Morera-Gómez, M., Contesini, F. J. & Mortensen, U. H., 2023, In: Journal of Fungi. 9, 1, 13 p., 16.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile71 Downloads (Pure) -
CRI-SPA: a high-throughput method for systematic genetic editing of yeast libraries
Cachera, P., Olsson, H., Coumou, H., Jensen, M. L., Sánchez, B. J., Strucko, T., van den Broek, M., Daran, J-M., Jensen, M. K., Sonnenschein, N., Lisby, M. & Mortensen, U. H., 2023, In: Nucleic Acids Research. 51, 17, 14 p., e91.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Downloads (Pure) -
Whole genome sequence characterization of Aspergillus terreus ATCC 20541 and genome comparison of the fungi A. terreus
Wu, H. Y., Mortensen, U. H., Chang, F. R. & Tsai, H., 2023, In: Scientific Reports. 13, 10 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile25 Downloads (Pure) -
Authentication of vanillin ex glucose – A first study on the influence of the glucose-source on the δ13C and δ2H value
Wilde, A. S., Strucko, T., Veje, C. R., Mortensen, U. H. & Duedahl-Olesen, L., 2022, In: Food Control. 131, 8 p., 108389.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile72 Downloads (Pure) -
A Versatile in Vivo DNA Assembly Toolbox for Fungal Strain Engineering
Jarczynska, Z. D., Garcia Vanegas, K., Deichmann, M., Nørskov Jensen, C., Scheeper, M. J., Futyma, M. E., Strucko, T., Jares Contesini, F., Sparholt Jørgensen, T., Blæsbjerg Hoof, J. & Hasbro Mortensen, U., 2022, In: ACS Synthetic Biology. 11, 10, p. 3251-3263 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile81 Downloads (Pure)
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Discovery of new fungal enzymes for degradation of thermoset plastics
Jagrelius, R. H., Mortensen, U. H. & Westh, P.
01/10/2023 → 30/09/2026
Project: PhD
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Discovery and Production of New Carbohydrate Active Enzymes
Gómez, M. M., Mortensen, U. H., Jares Contesini, F., Henrissat, B. P. & Nørholm, M.
01/05/2022 → 30/04/2025
Project: PhD
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Engineering feedback regulation for recombinant protein production
Kastberg, L. L. B., Mortensen, U. H., Förster, J. & Sudarsan, S.
01/01/2021 → 02/10/2024
Project: PhD
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An Active Learning Approach for the Exploration of Genetic Landscapes for MEtabolic Engineering
Cachera, P. P. J., Jensen, M. K., Mortensen, U. H., Alper, H. & Ceroni, F.
01/09/2020 → 31/08/2023
Project: PhD
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Genome reduction of a filamentous fungus
Rothschild-Mancinelli, K. R., Haas, H., Larsen, T. O., Nielsen, M. L., Frandsen, R. J. N. & Mortensen, U. H.
01/02/2018 → 11/02/2022
Project: PhD
Activities
- 1 Conference presentations
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Adaptive Laboratory Evolution of Saccharomyces cerevisiae Diploid Strains for Mannitol Utilization as a Carbon Source
Javier Porcayo Loza (Speaker) & Uffe Hasbro Mortensen (Other)
27 Aug 2017 → 1 Sept 2017Activity: Talks and presentations › Conference presentations
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