If you made any changes in Pure these will be visible here soon.

Research Output

Book chapter

Antibiotics, Biosynthesis, Generation of Novel Compounds: Wiley Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology

Weber, T., 2010, Wiley Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology. Flickinger, M. C. (ed.). John Wiley and Sons Inc.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Bioinformatics Tools for the Discovery of New Nonribosomal Peptides

Leclère, V., Weber, T., Jacques, P. & Pupin, M., 2016, Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols. Springer, Vol. 1401. p. 209-232 24 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

CRISPR-Cas9 Toolkit for Actinomycete Genome Editing

Tong, Y., Robertsen, H. L., Blin, K., Weber, T. & Lee, S. Y., 2018, Synthetic Metabolic Pathways. Vol. 1671. p. 163-184 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Comment/debate

Minimum Information about a Biosynthetic Gene cluster

Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., de Bruijn, I., Kim, H. U., Nielsen, J. & Weber, T., 2015, In : Nature Chemical Biology. 11, 9, p. 625-631 7 p.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
352 Downloads (Pure)
Conference abstract for conference

Filling The Gaps In The Kirromycin Biosynthetic Gene Cluster In Streptomyces Collinus Tü 365

Robertsen, H. L., Musiol-Kroll, E. M., Ding, L., Lee, S. Y. & Weber, T., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
78 Downloads (Pure)
Conference abstract in journal

Engineering of actinomycetes using CRISPR/Cas9 technologies

Weber, T., Tong, Y., Blin, K. & Lee, S. Y., 2016, In : Planta Medica. 81, S01, 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Conference abstract in proceedings

Genome Mining for antibiotics biosynthesis pathways with antiSMASH 3

Weber, T., Kim, H. U., Blin, K., Takano, E., Breitling, R. & Medema, M., 2014, Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby: Technical University of Denmark, 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

KirCII- promising tool for polyketide diversification

Musiol-Kroll, E. M., Härtner, T., Kulik, A., Wohlleben, W., Weber, T. & Lee, S. Y., 2014, Abstract Book - DTU Sustain Conference 2014. Kgs. Lyngby: Technical University of Denmark, 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Doctoral thesis
Editorial

Engineering of cell factories for the production of natural products

Weber, T., 2019, In : Natural Product Reports. 36, 9, p. 1231-1232

Research output: Contribution to journalEditorialResearchpeer-review

Introduction to the Special Issue “Bioinformatic tools and approaches for Synthetic Biology of natural products”

Weber, T., 2016, In : Synthetic and Systems Biotechnology. 1, 2, p. 67-68 2 p.

Research output: Contribution to journalEditorialResearchpeer-review

Open Access
File
403 Downloads (Pure)
Encyclopedia chapter

CLUSEAN, Overview

Nelson, K. E. (ed.), Weber, T. & Blin, K., 2012, Encyclopedia of Metagenomics . Springer Verlag

Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearchpeer-review

Journal article

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences: Nucleic Acids Research

Medema, M. H., Blin, K., Cimermancic, P., de Jager, V., Zakrzewski, P., Fischbach, M. A., Weber, T., Takano, E. & Breitling, R., 2011, In : Nucleic acids research. 39, p. W339-W346

Research output: Contribution to journalJournal articleResearchpeer-review

antiSMASH 2.0 – a versatile platform for genome mining of secondary metabolite producers

Blin, K., Medema, M. H., Kazempour, D., Fischbach, M., Breitling, R., Takano, E. & Weber, T., 2013, In : Nucleic acids research. 41, W1, p. W204-W212

Research output: Contribution to journalJournal articleResearchpeer-review

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

Weber, T., Blin, K., Duddela, S., Krug, D., Kim, H. U., Bruccoleri, R., Lee, S. Y., Fischbach, M. A., Müller, R. & Wohlleben, W., 2015, In : Nucleic acids research. 43, W1, p. W237-W243 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
666 Downloads (Pure)

antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification

Blin, K., Wolf, T., Chevrette, M. G., Lu, X., Schwalen, C. J., Kautsar, S. A., Suarez Duran, H. G., de Los Santos, E. L. C., Kim, H. U., Nave, M., Dickschat, J. S., Mitchell, D. A., Shelest, E., Breitling, R., Takano, E., Lee, S. Y., Weber, T. & Medema, M. H., 2017, In : Nucleic acids research. 45, p. W36-W41

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
338 Downloads (Pure)

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

Blin, K., Shaw, S., Steinke, K., Villebro, R., Ziemert, N., Lee, S. Y., Medema, M. H. & Weber, T., 2019, In : Nucleic acids research. 87, W2, p. W81-W87 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
176 Downloads (Pure)

Antitumor astins originate from the fungal endophyte Cyanodermella asteris living within the medicinal plant Aster tataricus

Schafhauser, T., Jahn, L., Kirchner, N., Kulik, A., Flor, L., Lang, A., Caradec, T., Fewer, D. P., Sivonen, K., van Berkel, W. J. H., Jacques, P., Weber, T., Gross, H., van Pée, K-H., Wohlleben, W. & Ludwig-Müller, J., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 52, p. 26909-26917

Research output: Contribution to journalJournal articleResearchpeer-review

Biosynthesis of Phenylnannolone A, a Multidrug Resistance Reversal Agent from the Halotolerant Myxobacterium Nannocystis pusilla B150

Bouhired, S. M., Crüsemann, M., Almeida, C., Weber, T., Piel, J., Schäberle, T. F. & König, G. M., 2014, In : ChemBioChem. 15, 5, p. 757-765

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
491 Downloads (Pure)

Characterization of the "pristinamycin supercluster" of Streptomyces pristinaespiralis

Mast, Y., Weber, T., Golz, M., Ort-Winklbauer, R., Gondran, A., Wohlleben, W. & Schinko, E., 2011, In : Microbial Biotechnology. 4, 2, p. 192-206 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CLUSEAN: a computer-based framework for the automated analysis of bacterial secondary metabolite biosynthetic gene clusters: Journal of Biotechnology

Weber, T., Rausch, C., Lopez, P., Hoof, I., Gaykova, V., Huson, D. H. & Wohlleben, W., 2009, In : Journal of biotechnology. 140, p. 13-17 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparative analysis and insights into the evolution of gene clusters for glycopeptide antibiotic biosynthesis

Donadio, S., Sosio, M., Stegmann, E., Weber, T. & Wohlleben, W., 2005, In : Molecular Genetics and Genomics. 274, p. 40-50 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17T (=DSM 44213T) producing (S,S)-N,N′-ethylenediaminedisuccinic acid

Stegmann, E., Albersmeier, A., Spohn, M., Gert, H., Weber, T., Wohlleben, W., Kalinowski, J. & Rückert, C., 2014, In : Journal of Biotechnology. 189, p. 46-47

Research output: Contribution to journalJournal articleResearchpeer-review

Complete genome sequence of the kirromycin producer Streptomyces collinus Tü 365 consisting of a linear chromosome and two linear plasmids

Rückert, C., Szczepanowski, R., Albersmeier, A., Goesmann, A., Iftime, D., Musiol-Kroll, E. M., Blin, K., Wohlleben, W., Pühler, A., Kalinowski, J. & Weber, T., 2013, In : Journal of biotechnology. 168, p. 739-740

Research output: Contribution to journalJournal articleResearchpeer-review

Complete Genome Sequences of 13 Bacillus subtilis Soil Isolates for Studying Secondary Metabolite Diversity

Kiesewalter, H. T., Lozano-Andrade, C. N., Maróti, G., Snyder, D., Snyder, D., Jørgensen, T. S., Weber, T. & Kovács, Á. T., 2020, In : Microbiology Resource Announcements. 9, 2, 3 p., e01406-19.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
72 Downloads (Pure)

CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

Tong, Y., Charusanti, P., Zhang, L., Weber, T. & Lee, S. Y., 2015, In : A C S Synthetic Biology. 4, 9, p. 1020-1029 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CRISPy-web: An online resource to design sgRNAs for CRISPR applications

Blin, K., Pedersen, L. E., Weber, T. & Lee, S. Y., 2016, In : Synthetic and Systems Biotechnology. 1, 2, p. 118-121 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
515 Downloads (Pure)

Cyanodermella asteris sp. nov. (Ostropales) from the inflorescence axis of Aster tataricus

Jahn, L., Schafhauser, T., Pan, S., Weber, T., Wohlleben, W., Fewer, D., Sivonen, K., Flor, L., van Pée, K-H., Caradec, T., Jacques, P., Huijbers, M. M. E., van Berkel, W. J. H. & Ludwig-Müller, J., 2017, In : Mycotaxon. 132, p. 107-123

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001.

Devi, S., Kiesewalter, H. T., Kovács, R., Frisvad, J. C., Weber, T., Larsen, T. O., Kovács, Á. T. & Ding, L., 2019, In : Synthetic and Systems Biotechnology. 4, 3, p. 142-149 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
182 Downloads (Pure)

Designing sgRNAs with CRISPy web: Tips and tricks of the trade

Blin, K., Lee, S. Y. & Weber, T., 2017, In : Lab Times. 1, p. 53

Research output: Contribution to journalJournal articleResearch

Open Access
File
279 Downloads (Pure)

Detection and quantification of a mycorrhization helper bacterium and a mycorrhizal fungus in plant-soil microcosms at different levels of complexity

Kurth, F., Zeitler, K., Feldhahn, L., Neu, T. R., Weber, T., Kristufek, V., Wubet, T., Herrmann, S., Buscot, F. & Tarkka, M. T., 2013, In : B M C Microbiology. 13, p. 205 1 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Differential proteomic analysis reveals novel links between primary metabolism and antibiotic production in Amycolatopsis balhimycina

Gallo, G., Renzone, G., Alduina, R., Stegmann, E., Weber, T., Eliasson Lantz, A., Thykær, J., Sangiorgi, F., Scaloni, A. & Puglia, A. M., 2010, In : Proteomics. 10, 7, p. 1336-1358

Research output: Contribution to journalJournal articleResearchpeer-review

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

Jiang, X., Ellabaan, M. M. H., Charusanti, P., Munck, C., Blin, K., Tong, Y., Weber, T., Sommer, M. O. A. & Lee, S. Y., 2017, In : Nature Communications. 8, 15784.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
419 Downloads (Pure)

Draft genome sequence of Talaromyces islandicus (“Penicillium islandicum”) WF-38-12, a neglected mold with significant biotechnological potential

Schafhauser, T., Wibberg, D., Rückert, C., Winkler, A., Flor, L., van Pée, K-H., Fewer, D. P., Sivonen, K., Jahn, L. & Weber, T., 2015, In : Journal of Biotechnology. 211, p. 101-102 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Draft Genome Sequence of the Microbispora sp. Strain ATCC-PTA-5024, Producing the Lantibiotic NAI-107

Sosio, M., Gallo, G., Pozzi, R., Serina, S., Monciardini, P., Bera, A., Stegmann, E. & Weber, T., 2014, In : Genome Announcements. 2, 1, p. e01198-13

Research output: Contribution to journalJournal articleResearchpeer-review

Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024

Gallo, G., Renzone, G., Palazzotto, E., Monciardini, P., Arena, S., Faddetta, T., Giardina, A., Alduina, R., Weber, T., Sangiorgi, F., Russo, A., Spinelli, G., Sosio, M., Scaloni, A. & Puglia, A. M., 2016, In : B M C Genomics. 17, 42, 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
289 Downloads (Pure)

Evidence that an additional mutation is required to tolerate insertional inactivation of the Streptomyces lividans recA gene

Vierling, S., Weber, T., Wohlleben, W. & Muth, G., 2001, In : Journal of Bacteriology. 183, p. 4374-4381 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Exploiting the genetic potential of polyketide producing streptomycetes

Weber, T., Welzel, K., Pelzer, S., Vente, A. & Wohlleben, W., 2003, In : Journal of Biotechnology. 106, p. 221-232 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

Robertsen, H. L., Musiol-Kroll, E. M., Ding, L., Laiple, K. J., Hofeditz, T., Wohlleben, W., Lee, S. Y., Grond, S. & Weber, T., 2018, In : Scientific Reports. 8, 9 p., 3230.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
265 Downloads (Pure)

Functional Genomics zur Suche und Optimierung neuer Wirkstoffe

Translated title of the contribution: Functional Genomics zur Suche und Optimierung neuer Wirkstoffe: GenomXpressWeber, T. & Wohlleben, W., 2009, In : Genomxpress. 9, p. 11-13 3 p.

Research output: Contribution to journalJournal articleResearch

Genome Mining Approaches to Bacterial Natural Product Discovery

Ziemert, N., Weber, T. & Medema, M. H., 2020, (Accepted/In press) In : Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Genome mining in Amycolatopsis balhimycina for ferredoxins capable of supporting cytochrome P450 enzymes involved in glycopeptide antibiotic biosynthesis

Geib, N., Weber, T., Wörtz, T., Zerbe, K., Wohlleben, W. & Robinson, J. A., 2010, In : F E M S Microbiology Letters. 306, p. 45-53 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Genome-scale metabolic representation of Amycolatopsis balhimycina

Vongsangnak, W., Figueiredo, L. F., Förster, J., Weber, T., Thykær, J., Stegmann, E., Wohlleben, W. & Nielsen, J., 2012, In : Biotechnology and Bioengineering (Print). 109, 7, p. 1798-1807

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
282 Downloads (Pure)

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

Tong, Y., Whitford, C. M., Robertsen, H. L., Blin, K., Jørgensen, T. S., Klitgaard, A. K., Gren, T., Jiang, X., Weber, T. & Lee, S. Y., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20366-20375

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
100 Downloads (Pure)

Identification and activation of novel biosynthetic gene clusters by genome mining in the kirromycin producer Streptomyces collinus Tü 365

Iftime, D., Kulik, A., Härtner, T., Rohrer, S., Niedermeyer, T. H. J., Stegmann, E., Weber, T. & Wohlleben, W., 2016, In : Journal of Industrial Microbiology and Biotechnology. 43, 2, p. 277-291 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Improved lanthipeptide detection and prediction for antiSMASH

Blin, K., Kazempour, D., Wohlleben, W. & Weber, T., 2014, In : P L o S One. 9, 2, 7 p., e89420.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
239 Downloads (Pure)

Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster

Thykær, J., Nielsen, J., Wohlleben, W., Weber, T., Gutknecht, M., Eliasson Lantz, A. & Stegmann, E., 2010, In : Metabolic Engineering. 12, 5, p. 455-461

Research output: Contribution to journalJournal articleResearchpeer-review

In silico tools for the analysis of antibiotic biosynthetic pathways.

Weber, T., 2014, In : International Journal of Medical Microbiology. 304, p. 230-235

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Isolation of the lysolipin gene cluster of Streptomyces tendae Tu 4042: Gene

Lopez, P., Hornung, A., Welzel, K., Unsin, C., Wohlleben, W., Weber, T. & Pelzer, S., 2010, In : Gene. 461, p. 5-14 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris: The anti-cancer bisanthraquinone skyrin

Jahn, L., Schafhauser, T., Wibberg, D., Rückert, C., Winkler, A., Kulik, A., Weber, T., Flor, L., van Pée, K-H., Kalinowski, J., Ludwig-Müllera, J. & Wohlleben, W., 2017, In : Journal of Biotechnology. 257, p. 233-239

Research output: Contribution to journalJournal articleResearchpeer-review