Publications per year
Publications per year
Personal profile
Profile
Tilmann Weber is Professor for Natural Products Genome Mining and Associate Scientific Director of the Natural Products Genome Mining group at the Novo Nordisk Foundation Center for Biosustainability of the Technical University of Denmark. His main research interest is focused on deciphering the molecular pathways and engineering the biosynthesis of natural products by combining genetic, biochemical and bioinformatics methods. He is a pioneer in developing software for the automated genome mining (CLUSEAN, antiSMASH, antiSMASH-DB) and analysis of secondary metabolite biosynthetic pathways. His group was able to firstly elucidate the biosynthetic pathways of the elfamycin family of antibiotics and is deeply involved in developing CRISPR-based metabolic engineering tools for actinomycetes.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Extraction and Oxford Nanopore sequencing of genomic DNA from filamentous Actinobacteria
Alvarez-Arevalo, M., Sterndorff, E. B., Faurdal, D., Jørgensen, T. S., Mourched, A-S., Vuksanovic, O., Saha, S. & Weber, T., 2023, In: STAR Protocols. 4, 1, 24 p., 101955.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Downloads (Pure) -
MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters
Terlouw, B. R., Blin, K., Navarro-Muñoz, J. C., Avalon, N. E., Chevrette, M. G., Egbert, S., Lee, S., Meijer, D., Recchia, M. J. J., Reitz, Z. L., van Santen, J. A., Selem-Mojica, N., Tørring, T., Zaroubi, L., Alanjary, M., Aleti, G., Aguilar, C., Al-Salihi, S. A. A., Augustijn, H. E., Avelar-Rivas, J. A., & 62 others, 2023, In: Nucleic Acids Research. 51, D1, p. D603–D610 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Downloads (Pure) -
Complete Genome Sequence of the Collinolactone Producer Streptomyces sp. Strain Go40/10
Sterndorff, E. B., Jørgensen, T. S., Garzon, J. F. G., Schmid, J. C., Grond, S. & Weber, T., 2022, In: Microbiology Resource Announcements. 11, 8, 2 p.Research output: Contribution to journal › Contribution to newspaper - Comment/debate
Open AccessFile7 Downloads (Pure) -
Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family
Carretero-Molina, D., Ortiz-López, F. J., Gren, T., Oves-Costales, D., Martín, J., Román-Hurtado, F., Sparholt Jørgensen, T., de la Cruz, M., Díaz, C., Vicente, F., Blin, K., Reyes, F., Weber, T. & Genilloud, O., 2022, In: Organic Chemistry Frontiers. 9, 2, p. 462-470 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-quality genome-scale metabolic network reconstruction of probiotic bacterium Escherichia coli Nissle 1917
van ‘t Hof, M., Mohite, O. S., Monk, J. M., Weber, T., Palsson, B. O. & Sommer, M. O. A., 2022, In: BMC Bioinformatics. 23, 1, 23 p., 566.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Pure)
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MAGic-MOLFUN: MSCA Doctoral Network: Matching Genes with Molecules for Functional Analysis
Weber, T., Blin, K. & Larsen, T. O.
01/01/2023 → 31/12/2026
Project: Research
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Literate Programming of Biology
Levassor, L., Sonnenschein, N., Madsen, J. & Weber, T.
01/04/2022 → 31/03/2025
Project: PhD
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Diversity and Evolution of bacterial Biosynthetic Gene Clusters
Nielsen, L. J. D., Kovács, Á. T. & Weber, T.
01/01/2022 → 31/12/2024
Project: PhD
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Data-Driven Natural Products Discovery in Soil Microbial Interaction
Nuhamunada, M., Weber, T., Mohite, O. S. & Arumugam, M.
01/09/2021 → 31/08/2024
Project: PhD
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Rhythmicity-tuned Secondary Metabolites Production in Actinobacteria
Yang, Z., Ding, L. & Weber, T.
01/12/2020 → 30/11/2023
Project: PhD
Activities
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CRISPR tools for metabolic engineering of actinomycetes
Tilmann Weber (Invited speaker)
20 Jun 2022Activity: Talks and presentations › Conference presentations
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Synthetic biology approaches to engineer natural product biosynthesis in actinomycetes
Tilmann Weber (Guest lecturer)
13 Oct 2022Activity: Talks and presentations › Guest lectures, external teaching and course activities at other universities
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Genome mining with antiSMASH
Tilmann Weber (Panel member) & Kai Blin (Invited speaker)
9 Mar 2022Activity: Talks and presentations › Conference presentations
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Genome engineering of streptomycetes with the CFB CRISPR toolkit
Tilmann Weber (Keynote speaker)
23 Sep 2022Activity: Talks and presentations › Conference presentations
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Mining soils for drugs (and more) – Omics-based approaches for the discovery of specialized metabolites
Tilmann Weber (Keynote speaker)
1 Jul 2022Activity: Talks and presentations › Conference presentations
Prizes
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Clarivate Highly Cited Researcher 2020
Weber, Tilmann (Recipient), 2020
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2021
Weber, Tilmann (Recipient), 16 Nov 2021
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2022
Weber, Tilmann (Recipient), 15 Nov 2022
Prize: Prizes, scholarships, distinctions
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Corrits Akademiske Rejselegat
Weber, Tilmann (Recipient), 12 Feb 2019
Prize: Prizes, scholarships, distinctions
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Guest Professorship at the East China University of Science and Technology, Shanghai, China
Weber, Tilmann (Recipient), 20 Nov 2019
Prize: Prizes, scholarships, distinctions
Press / Media
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Closing ceremony of "Small World Initiative" course at University of Santiago de Compostela, Spain
04/05/2018
1 Media contribution
Press/Media: Press / Media
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Millions for research into antibiotic resistance and better drugs
Tilmann Weber, Pep Charusanti, Sang Yup Lee & Bernhard Palsson
26/01/2017 → 26/12/2017
2 items of Media coverage, 2 Media contributions
Press/Media: Press / Media
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Video and Blog-post / interview at sciencenews.dk on iimena project (NNF Challenge Grant)
24/11/2017
1 item of Media coverage
Press/Media: Press / Media
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Scientists solve 30-year old mystery on how resistance genes spread
Tilmann Weber, Morten Otto Alexander Sommer, Xinglin Jiang, Sang Yup Lee, Mostafa M Hashim Ellabaan, Pep Charusanti, Christian Munck, Kai Blin & Yaojun Tong
15/06/2017
1 Media contribution
Press/Media: Press / Media
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Scientists discover how to make ‘click-on’ antibiotics
Tilmann Weber, Sang Yup Lee & Ewa Maria Musiol-Kroll
04/04/2017
1 Media contribution
Press/Media: Press / Media