Research output per year
Research output per year
Research output
- 1 - 50 out of 310 results
Search results
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2025
Comparative genomics of Aspergillus nidulans and section Nidulantes
Theobald, S., Vesth, T., Nybo, J. L., Frisvad, J. C., Kjærbølling, I., Mondo, S., LaButti, K., Haridas, S., Riley, R., Kuo, A. A., Salamov, A. A., Pangilinan, J., Lipzen, A., Koriabine, M., Yan, M., Barry, K., Clum, A., Lyhne, E. K., Drula, E. & Wiebenga, A. & 17 others, , 2025, In: Current Research in Microbial Sciences. 8, 13 p., 100342.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Pure) -
Extracellular vesicles modulate metabolic processes in Prymnesium parvum, the causative species of algal blooms
Silva-Núñez, A., Wang, X., Donoso-Quezada, J., Sonnenschein, E. C., Lukassen, M. V., Hansen, P. J., González-Valdez, J. & Larsen, T. O., 2025, In: Chemosphere. 377, 13 p., 144302.Research output: Contribution to journal › Journal article › Research › peer-review
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Malformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade
Phillips, E., van Enk, S., Kildgaard, S., Schlue, S., Göttmann, M., Jennings, V., Bethke, F., Müller, G., Herold-Mende, C., Pastor-Flores, D., Schneider, M., Helm, D., Ostenfeld Larsen, T. & Goidts, V., 2025, In: Molecular Oncology. 19, 3, p. 785-807Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure) -
Section-level genome sequencing and comparative genomics of Aspergillus sections Cavernicolus and Usti
Nybo, J. L., Vesth, T. C., Theobald, S., Frisvad, J. C., Larsen, T. O., Kjaerboelling, I., Rothschild-Mancinelli, K., Lyhne, E. K., Barry, K., Clum, A., Yoshinaga, Y., Ledsgaard, L., Daum, C., Lipzen, A., Kuo, A., Riley, R., Mondo, S., Labutti, K., Haridas, S. & Pangalinan, J. & 17 others, , 2025, In: Studies in Mycology. 111, p. 101-114Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
The cytotoxic and hemolytic potential of karmitoxin from Karlodinium armiger and how it interacts with sterols
Prause, H.-C., Hochmayr, N., Yu, Y., Larsen, T. O., Hansen, P. J., Del Favero, G., Marko, D., Place, A. & Varga, E., 2025, In: Harmful Algae. 143, 9 p., 102817.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Downloads (Pure) -
2024
A high-quality genome of the early diverging tychoplanktonic diatom Paralia guyana
Jian, J., Du, F., Wang, B., Fang, X., Larsen, T. O., Li, Y. & Sonnenschein, E. C., 2024, In: Scientific Data. 11, 7 p., 1175.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Downloads (Pure) -
Apiospora arundinis, a panoply of carbohydrate-active enzymes and secondary metabolites
Sørensen, T., Petersen, C., Muurmann, A. T., Christiansen, J. V., Brundtø, M. L., Overgaard, C. K., Boysen, A. T., Wollenberg, R. D., Larsen, T. O., Sørensen, J. L., Nielsen, K. L. & Sondergaard, T. E., 2024, In: IMA Fungus. 15, 17 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile45 Downloads (Pure) -
Cytotoxicity of Prymnesium parvum extracts and prymnesin analogs on epithelial fish gill cells RTgill-W1 and the human colon cell line HCEC-1CT
Varga, E., Prause, H.-C., Riepl, M., Hochmayr, N., Berk, D., Attakpah, E., Kiss, E., Medić, N., Del Favero, G., Larsen, T. O., Hansen, P. J. & Marko, D., 2024, In: Archives of Toxicology. 98, p. 999-1014 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile43 Downloads (Pure) -
Enhanced surface colonisation and competition during bacterial adaptation to a fungus
Richter, A., Blei, F., Hu, G., Schwitalla, J. W., Lozano-Andrade, C. N., Xie, J., Jarmusch, S. A., Wibowo, M., Kjeldgaard, B., Surabhi, S., Xu, X., Jautzus, T., Phippen, C. B. W., Tyc, O., Arentshorst, M., Wang, Y., Garbeva, P., Larsen, T. O., Ram, A. F. J. & van den Hondel, C. A. M. & 2 others, , 2024, In: Nature Communications. 15, 13 p., 4486.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile23 Downloads (Pure) -
Genomic Analysis of Aspergillus Section Terrei Reveals a High Potential in Secondary Metabolite Production and Plant Biomass Degradation
Theobald, S., Vesth, T. C., Geib, E., Nybo, J. L., Frisvad, J. C., Larsen, T. O., Kuo, A., LaButti, K., Lyhne, E. K., Kjærbølling, I., Ledsgaard, L., Barry, K., Clum, A., Chen, C., Nolan, M., Sandor, L., Lipzen, A., Mondo, S., Pangilinan, J. & Salamov, A. & 15 others, , 2024, In: Journal of Fungi. 10, 7, 17 p., 507.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile13 Downloads (Pure) -
How relevant are sterols in the mode of action of prymnesins?
Prause, H.-C., Berk, D., Alves-de-Souza, C., Hansen, P. J., Larsen, T. O., Marko, D., Favero, G. D., Place, A. & Varga, E., 2024, In: Aquatic Toxicology. 276, 12 p., 107080.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of biotic and abiotic factors on prymnesin profiles in three strains of Prymnesium parvum
Bannon, C. C., Wang, X., Uhlig, S., Samdal, I. A., McCarron, P., Larsen, T. O. & Mudge, E. M., 2024, In: Algal Research. 78, 11 p., 103390.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Downloads (Pure) -
Insights into the nature of ichthyotoxins from the Chrysochromulina leadbeateri blooms in Northern Norwegian fjords
Wang, X., Fon, M., Andersen, A. J. C., Solhaug, A., Ingebrigtsen, R. A., Samdal, I. A., Uhlig, S., Miles, C. O., Edvardsen, B. & Larsen, T. O., 2024, In: Harmful Algae. 137, 12 p., 102681.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-read genome sequencing provides novel insights into the harmful algal bloom species Prymnesium parvum
Jian, J., Wu, Z., Silva-Núñez, A., Liu, Y., Li, X., Zheng, X., Luo, B., Fang, X., Workman, C. T., Larsen, T. O., Hansen, P. J. & Sonnenschein, E. C., 2024, In: Science of the Total Environment. 908, 14 p., 168042.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile45 Downloads (Pure) -
The role and fate of patulin in apple-associated fungal-fungal interactions
Clemmensen, S. E., Cowled, M. S., Kromphardt, K. J. K., Frisvad, J. C., Larsen, T. O. & Frandsen, R. J. N., 2024, In: Fungal Ecology. 69, 10 p., 101341.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile44 Downloads (Pure) -
Two high-quality Prototheca zopfii genomes provide new insights into their evolution as obligate algal heterotrophs and their pathogenicity
Jian, J., Wang, Z., Chen, C., Workman, C. T., Fang, X., Larsen, T. O., Guo, J. & Sonnenschein, E. C., 2024, In: Microbiology Spectrum. 12, 8, 18 p., e0414823.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile25 Downloads (Pure) -
Unveiling the fungal diversity and associated secondary metabolism on black apples
Cowled, M. S., Phippen, C. B. W., Kromphardt, K. J. K., Clemmensen, S. E., Frandsen, R. J. N., Frisvad, J. C. & Larsen, T. O., 2024, In: Applied and Environmental Microbiology. 90, 7, 19 p., e0034224.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Downloads (Pure) -
2023
Current status of secondary metabolite pathways linked to their related biosynthetic gene clusters in Aspergillus section Nigri
Wang, X., Jarmusch, S. A., Frisvad, J. C. & Larsen, T. O., 2023, In: Natural Product Reports. 40, 2, p. 237-274 38 p.Research output: Contribution to journal › Review › peer-review
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Demonstrating the Use of a Fungal Synthesized Quinone in a Redox Flow Battery
Wilhelmsen, C. O., Kristensen, S. B., Nolte, O., Volodin, I. A., Christiansen, J. V., Isbrandt, T., Sørensen, T., Petersen, C., Sondergaard, T. E., Lehmann Nielsen, K., Larsen, T. O., Frisvad, J. C., Hager, M. D., Schubert, U. S., Muff, J. & Sørensen, J. L., 2023, In: Batteries and Supercaps. 6, 1, 12 p., e202200365.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile148 Downloads (Pure) -
Fish-Killing Marine Algal Blooms: Causative Organisms, Ichthyotoxic Mechanisms, Impacts and Mitigation.
Hallegraeff, G. M., Anderson, D. M., Davidson, K., Gianella, F., Hansen, P. J., Hegaret, H., Iwataki, M., Larsen, T. O., Mardones, J., MacKenzie, L. & Rensel, J. E., 2023, Paris, France: UNESCO. 96 p. (IOC Manuals and Guides, Vol. 93).Research output: Book/Report › Report › Commissioned
Open AccessFile301 Downloads (Pure) -
On the Capacity and Stability of a Biosynthesized Bis-quinone Flow Battery Negolyte
Wilhelmsen, C. O., Pasadakis-Kavounis, A., Christiansen, J. V., Isbrandt, T., Almind, M. R., Larsen, T. O., Hjelm, J., Sørensen, J. L. & Muff, J., 2023, In: ACS Sustainable Chemistry & Engineering. 11, 24, p. 9206-9215 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation and Degradation of Secondary Metabolites in Pseudomonas Protegens by Soil- and Plant Associated Bacteria
Hansen, M., Wibowo, M., Jarmusch, S., Larsen, T., Dènes, Z., Kovacs, A., Lozano, C., Kaltenyte, A., Pittroff, S., Andersen, A., Strube, M. & Jelsbak, L., 2023, p. 88-88. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
Open AccessFile95 Downloads (Pure) -
Trichoderma harzianum Peptaibols Stimulate Plant Plasma Membrane H+-ATPase Activity
Bjørk, P. K., Johansen, N. T., Havshøi, N. W., Rasmussen, S. A., Ipsen, J. Ø., Isbrandt, T., Larsen, T. O. & Fuglsang, A. T., 2023, In: ACS Omega. 8, 38, p. 34928-34937 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile40 Downloads (Pure) -
2022
A Concise Total Synthesis of the Fungal Isoquinoline Alkaloid TMC-120B
Haidar, A. K., Kjeldsen, N. D., Troelsen, N. S., Previtali, V., Lundquist, K. P., Larsen, T. O. & Clausen, M. H., 2022, In: Molecules. 27, 2, 9 p., 521.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile211 Downloads (Pure) -
A Molecular Networking Based Discovery of Diketopiperazine Heterodimers and Aspergillicins from Aspergillus caelatus
Wang, X., Serrano, R., González-Menéndez, V., Mackenzie, T. A., Ramos, M. C., Frisvad, J. C. & Larsen, T. O., 2022, In: Journal of Natural Products. 85, 1, p. 25-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile40 Downloads (Pure) -
Biosynthesis of Calipyridone A Represents a Fungal 2-Pyridone Formation without Ring Expansion in Aspergillus californicus
Guo, Y., Contesini, F. J., Wang, X., Ghidinelli, S., Tornby, D. S., Andersen, T. E., Mortensen, U. H. & Larsen, T. O., 2022, In: Organic Letters. 24, 3, p. 804-808 5 p.Research output: Contribution to journal › Letter › peer-review
Open AccessFile27 Downloads (Pure) -
Deep Genotypic Species Delimitation of Aspergillus Section Flavi Isolated from Brazilian Foodstuffs and the Description of Aspergillus annui sp. nov. and Aspergillus saccharicola sp. nov
Silva, J. J., Fungaro, M. H. P., Wang, X., Larsen, T. O., Frisvad, J. C., Taniwaki, M. H. & Iamanaka, B. T., 2022, In: Journal of Fungi. 8, 12, 21 p., 1279.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile66 Downloads (Pure) -
Fishing for antiseizure drugs in the North Sea, the discovery of halimide and plinabulin
Copmans, D., Kildgaard, S., Roux, E., Partoens, M., Steurs, G., Wang, X., De Borggraeve, W. M., Esguerra, C. V., Crawford, A. D., Larsen, T. O. & de Witte, P. A. M., 2022, In: Epilepsia. 63, p. 97-97 1 p., 718.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin
Copmans, D., Kildgaard, S., Roux, E., Partoens, M., Steurs, G., Wang, X., De Borggraeve, W. M., Esguerra, C. V., Crawford, A. D., Larsen, T. O. & de Witte, P. A. M., 2022, In: Pharmaceuticals. 15, 2, 26 p., 247.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile94 Downloads (Pure) -
Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp.
Nielsen, J. B., Gren, T., Mohite, O. S., Jørgensen, T. S., Klitgaard, A. K., Mourched, A.-S., Blin, K., Oves-Costales, D., Genilloud, O., Larsen, T. O., Tanner, D., Weber, T., Gotfredsen, C. H. & Charusanti, P., 2022, In: ACS chemical biology. 17, 9, p. 2411-2417 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxepinamides L and M, two new oxepine-pyrimidinone-ketopiperazine type nonribosomal peptides from Aspergillus californicus
Guo, Y., Ghidinelli, S., de la Cruz, M., Mackenzie, T. A., Ramos, M. C., Sánchez, P., Vicente, F., Genilloud, O. & Larsen, T. O., 2022, In: Natural Product Research. 36, 8, p. 2043-2048 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phoenicin Switch: Discovering the Trigger for Radical Phoenicin Production in Multiple Wild-Type Penicillium Species
Christiansen, J. V., Isbrandt, T., Asferg, R., Jarmusch, S. A., Larsen, T. O. & Frisvad, J. C., 2022, In: Applied and Environmental Microbiology. 88, 12, 16 p., e0030222.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile84 Downloads (Pure) -
Production of Fungal Quinones: Problems and Prospects
Christiansen, J. V., Larsen, T. O. & Frisvad, J. C., 2022, In: Biomolecules. 12, 8, 15 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile60 Downloads (Pure) -
Sequential interspecies interactions affect production of antimicrobial secondary metabolites in Pseudomonas protegens DTU9.1
Hansen, M. L., Wibowo, M., Jarmusch, S. A., Larsen, T. O. & Jelsbak, L., 2022, In: ISME Journal. 16, p. 2680-2690 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Solonamides, a Group of Cyclodepsipeptides, Influence Motility in the Native Producer Photobacterium galatheae S2753
Zhang, S.-D., Lindqvist, L. L., Isbrandt, T., Borre, I. L., Wibowo, M., Nielsen, M. W., Ding, L., Larsen, T. O. & Gram, L., 2022, In: Applied and Environmental Microbiology. 88, 17, e0110522.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
The coupling between irradiance, growth, photosynthesis and prymnesin cell quota and production in two strains of the bloom-forming haptophyte, Prymnesium parvum
Medić, N., Varga, E., Waal, D. B. V. D., Larsen, T. O. & Hansen, P. J., 2022, In: Harmful Algae. 112, 8 p., 102173.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Downloads (Pure) -
Vigtig grundforskning sker ikke af sig selv. Det skal prioriteres af politikere – og vælgere
Agger, J. W., Hachem, M. A., Laustsen-Kiel, A. H., Damgaard, R. B., Workman, C., Dirac, A., Brix Pedersen, S., Morth, J. P., Martinussen, J., Voldborg, B., Holck, J., Larsen, T. O., Jelsbak, L., Mateiu, R., Pedersen, L. E., Marcussen, M. H., Zeuner, B., Bentzon-Tilia, M., Emnéus, J. & Møller, M. S. & 5 others, , 2022, In: Information.Research output: Contribution to journal › Contribution to newspaper - Comment/debate
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2021
Alkali Metal- and Acid-Catalyzed Interconversion of Goniodomin A with Congeners B and C
Harris, C. M., Krock, B., Tillmann, U., Tainter, C. J., Stec, D. F., Andersen, A. J. C., Larsen, T. O., Reece, K. S. & Harris, T. M., 2021, In: Journal of Natural Products. 84, 9, p. 2554-2567 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioactive Ascochlorin Analogues from the Marine-Derived Fungus Stilbella fimetaria
Subko, K., Kildgaard, S., Vicente, F., Reyes, F., Genilloud, O. & Larsen, T. O., 2021, In: Marine Drugs. 19, 2, 14 p., 46.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile69 Downloads (Pure) -
Chitin Degradation Machinery and Secondary Metabolite Profiles in the Marine Bacterium Pseudoalteromonas rubra S4059
Wang, X., Isbrandt, T., Strube, M. L., Paulsen, S. S., Nielsen, M. W., Buijs, Y., Schoof, E. M., Larsen, T. O., Gram, L. & Zhang, S.-D., 2021, In: Marine Drugs. 19, 2, 17 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile167 Downloads (Pure) -
Enhancement of antibiotic production by co-cultivation of two antibiotic producing marine Vibrionaceae strains
Buijs, Y., Zhang, S.-D., Jørgensen, K. M., Isbrandt, T., Larsen, T. O. & Gram, L., 2021, In: FEMS Microbiology Ecology. 97, 4, 10 p., fiab041.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile221 Downloads (Pure) -
Fungal quinones: diversity, producers, and applications of quinones from Aspergillus, Penicillium, Talaromyces, Fusarium, and Arthrinium
Christiansen, J. V., Isbrandt, T., Petersen, C., Sondergaard, T. E., Nielsen, M. R., Pedersen, T. B., Sørensen, J. L., Larsen, T. O. & Frisvad, J. C., 2021, In: Applied Microbiology and Biotechnology. 105, p. 8157-8193 37 p.Research output: Contribution to journal › Review › peer-review
Open AccessFile527 Downloads (Pure) -
Genetic origin of homopyrones, a rare type of hybrid phenylpropanoid- and polyketide-derived yellow pigments from Aspergillus homomorphus
Futyma, M. E., Guo, Y., Hoeck, C., Hoof, J. B., Gotfredsen, C. H., Mortensen, U. H. & Larsen, T. O., 2021, In: Applied Microbiology and Biotechnology. 105, p. 5113-5121 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and Chemical Diversity of Bacillus subtilis Secondary Metabolites against Plant Pathogenic Fungi
Kiesewalter, H. T., Lozano-Andrade, C. N., Wibowo, M., Strube, M. L., Maróti, G., Snyder, D., Jørgensen, T. S., Larsen, T. O., Cooper, V. S., Weber, T. & Kovács, Á. T., 2021, In: mSystems. 6, 1, 15 p., e00770-20.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile256 Downloads (Pure) -
Holomycin, an antibiotic secondary metabolite, is required for biofilm formation of the native producer Photobacterium galatheae S2753
Zhang, S.-D., Isbrandt, T., Lindqvist, L. L., Larsen, T. O. & Gram, L., 2021, In: Applied and Environmental Microbiology. 87, 11, 15 p., e00169-21.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile120 Downloads (Pure) -
Identification and Verification of the Prodigiosin Biosynthetic Gene Cluster (BGC) in Pseudoalteromonas rubra S4059
Wang, X., Isbrandt, T., Christensen, E. Ø., Melchiorsen, J., Larsen, T. O., Zhang, S.-D. & Gram, L., 2021, In: Microbiology Spectrum. 9, 2, 11 p., e01171-21.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile101 Downloads (Pure) -
Mass Spectrometry-Based Network Analysis Reveals New Insights Into the Chemodiversity of 28 Species in Aspergillus section Flavi
Wang, X., Subko, K., Kildgaard, S., C. Frisvad, J. & O. Larsen, T., 2021, In: Frontiers in Fungal Biology. 2, 13 p., 719420.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile177 Downloads (Pure) -
Mass Spectrometry guided discovery and design of novel Asperphenamate analogues from Penicilium astrolabium reveals an extraordinary NRPS flexibility
Subko, K., Wang, X., Nielsen, F. H., Petersen, T. I., Gotfredsen, C. H., Ramos, C., Mackenzie, T., Vicente, F., Genilloud, O., Frisvad, J. C. & Larsen, T. O., 2021, In: Frontiers in Microbiology. 11, 13 p., 618730.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile277 Downloads (Pure) -
New naphthyl derivatives from Aspergillus californicus
Guo, Y., Ghidinelli, S., de la Cruz, M., Mackenzie, T. A., Ramos, M. C., Sánchez, P., Vicente, F., Genilloud, O. & Larsen, T. O., 2021, In: The Journal of Antibiotics. 74, p. 111-114 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polycyclic Tetramate Macrolactams—A Group of Natural Bioactive Metallophores
Ding, L., Zhang, S.-D., Kasem Haidar, A., Bajimaya, M., Guo, Y., Ostenfeld Larsen, T. & Gram, L., 2021, In: Frontiers in Chemistry. 9, 8 p., 772858.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile78 Downloads (Pure)