Research output per year
Research output per year
Personal profile
Profile
Naturstoffer fra mikroorganismer
Thomas Ostenfeld Larsen forsker i naturstofkemi fra skimmelsvampe og andre mikroorganismer. Naturstoffer er små organiske molekyler, som ofte er bioaktive. Det betyder, at de kan have gavnlige effekter, der kan udskilles i fødevarer eller bruges til at fremstille nye former for antibiotika eller anticancer stoffer og et fokus er således at opdage helt nye stoffer. Naturstoffer besidder dog ikke kun gavnlige effekter og kan i de rigtige mængder og koncentrationer være generelt sundhedsskadelige og kræftfremkaldende.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Research output
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Comparative genomics of Aspergillus nidulans and section Nidulantes
Theobald, S., Vesth, T., Nybo, J. L., Frisvad, J. C., Kjærbølling, I., Mondo, S., LaButti, K., Haridas, S., Riley, R., Kuo, A. A., Salamov, A. A., Pangilinan, J., Lipzen, A., Koriabine, M., Yan, M., Barry, K., Clum, A., Lyhne, E. K., Drula, E. & Wiebenga, A. & 17 others, , 2025, In: Current Research in Microbial Sciences. 8, 13 p., 100342.Research output: Contribution to journal › Journal article › Research › peer-review
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Malformin C preferentially kills glioblastoma stem-like cells via concerted induction of proteotoxic stress and autophagic flux blockade
Phillips, E., van Enk, S., Kildgaard, S., Schlue, S., Göttmann, M., Jennings, V., Bethke, F., Müller, G., Herold-Mende, C., Pastor-Flores, D., Schneider, M., Helm, D., Ostenfeld Larsen, T. & Goidts, V., 2025, In: Molecular Oncology. 19, 3, p. 785-807Research output: Contribution to journal › Journal article › Research › peer-review
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The cytotoxic and hemolytic potential of karmitoxin from Karlodinium armiger and how it interacts with sterols
Prause, H.-C., Hochmayr, N., Yu, Y., Larsen, T. O., Hansen, P. J., Del Favero, G., Marko, D., Place, A. & Varga, E., 2025, In: Harmful Algae. 143, 9 p., 102817.Research output: Contribution to journal › Journal article › Research › peer-review
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A high-quality genome of the early diverging tychoplanktonic diatom Paralia guyana
Jian, J., Du, F., Wang, B., Fang, X., Larsen, T. O., Li, Y. & Sonnenschein, E. C., 2024, In: Scientific Data. 11, 7 p., 1175.Research output: Contribution to journal › Journal article › Research › peer-review
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Apiospora arundinis, a panoply of carbohydrate-active enzymes and secondary metabolites
Sørensen, T., Petersen, C., Muurmann, A. T., Christiansen, J. V., Brundtø, M. L., Overgaard, C. K., Boysen, A. T., Wollenberg, R. D., Larsen, T. O., Sørensen, J. L., Nielsen, K. L. & Sondergaard, T. E., 2024, In: IMA Fungus. 15, 17 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile
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The role of biotransformations in marine and soil microbiomes
Pham, Q. K. (PhD Student), Larsen, T. O. (Main Supervisor) & Jarmusch, S. A. (Supervisor)
01/06/2024 → 31/05/2027
Project: PhD
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BASF-DTU PhD Secondary metabolite gene clusters
Holm, V. (PhD Student), Mortensen, U. H. (Main Supervisor), Larsen, T. O. (Supervisor), Meyer, A. S. (Supervisor) & Haefner, S. (Supervisor)
01/02/2024 → 31/01/2027
Project: PhD
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BASF-DTU Maximizing recombinant protein overexpression and expression efficacy prediction
Lund, H. M. D. (PhD Student), Meyer, A. S. (Main Supervisor), Larsen, T. O. (Supervisor), Mortensen, U. H. (Supervisor) & Haefner, S. (Supervisor)
01/02/2024 → 31/01/2027
Project: PhD
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Fungal metabolomics-driven discovery of natural products
Romero, A. (PhD Student), Weber, T. (Main Supervisor) & Larsen, T. O. (Supervisor)
01/09/2023 → 31/08/2026
Project: PhD
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MAGic-MOLFUN: MSCA Doctoral Network: Matching Genes with Molecules for Functional Analysis
Weber, T. (PI), Blin, K. (PI) & Larsen, T. O. (PI)
01/01/2023 → 31/12/2026
Project: Research
Activities
- 2 Conference presentations
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32 nd Mycotoxin Workshop: Mycotoxins and other secondary metabolites in maize silage
Larsen, T. O. (Speaker)
14 Jun 2010Activity: Talks and presentations › Conference presentations
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Biotechnology and Analytical Natural Product Chemistry of Aspergillus and Penicillium: Presented at: National Institute for Cellular Biotechnology and Department of Biology
Larsen, T. O. (Speaker)
1 Jan 2009 → …Activity: Talks and presentations › Conference presentations