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2019
Distinct transcriptional profiles of the female, male and finasteride-induced feminized male anogenital region in rat fetuses
Lindgren Schwartz, C. V., Vinggaard, A. M., Christiansen, S., Darde, T. A., Chalmel, F. & Svingen, T., 2019, In: Toxicological Sciences. 169, 1, p. 303-311Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile365 Downloads (Pure) -
DTU Fødevareinstituttet i front for at forebygge sygdomme
Kornholt, H., Svingen, T., Aarestrup, F. M. & Poulsen, M., 2019, In: Miljø og sundhed. 25, 2, p. 13-17Research output: Contribution to journal › Journal article › Research
Open AccessFile409 Downloads (Pure) -
In vitro and in vivo endocrine disrupting effects of the azole fungicides triticonazole and flusilazole
Draskau, M. K., Boberg, J., Taxvig, C., Pedersen, M., Frandsen, H. L., Christiansen, S. & Svingen, T., 2019, In: Environmental Pollution. 255, Part 2, 11 p., 113309.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile297 Downloads (Pure) -
Validation of endogenous reference genes in rat cerebral cortex for RT-qPCR analyses in developmental toxicity studies
Ramhøj, L., Petersen, M. A. & Svingen, T., 2019, In: PeerJ. 7, 13 p., e7181.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile228 Downloads (Pure) -
2018
Effects on metabolic parameters in young rats born with low birth weight after exposure to a mixture of pesticides
Svingen, T., Ramhøj, L., Egebjerg, K. M., Christiansen, S., Petersen, M. A., Vinggaard, A. M. & Hass, U., 2018, In: Scientific Reports. 8, 10 p., 305.Research output: Contribution to journal › Journal article › Research › peer-review
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Exposure to a glyphosate-based herbicide formulation, but not glyphosate alone, has only minor effects on adult rat testis
Johansson, H. K. L., Schwartz, C. L., Nielsen, L. N., Boberg, J., Vinggaard, A. M., Bahl, M. I. & Svingen, T., 2018, In: Reproductive Toxicology. 82, p. 25-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile589 Downloads (Pure) -
Hvorfor drenge bliver til drenge og piger bliver til piger samt hvordan kemikalier kan forstyrre den udvikling
Svingen, T., 2018, In: Miljø og sundhed. 24, 3, p. 31-32Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile186 Downloads (Pure) -
Mere tid til forskning på den naturvidenskabelige ph.d.-uddannelse
Rasmussen, P. H. & Svingen, T., 2018, In: Dansk Kemi. 99, 3, p. 4-4Research output: Contribution to journal › Journal article › Communication
Open AccessFile133 Downloads (Pure) -
Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination
Zhao, L., Wang, C., Lehman, M. L., He, M., An, J., Svingen, T., Spiller, C. M., Ng, E. T., Nelson, C. C. & Koopman, P., 2018, In: Molecular and Cellular Endocrinology. 478, p. 84-96Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile320 Downloads (Pure) -
2017
An effect-directed strategy for characterizing emerging chemicals in food contact materials made from paper and board
Rosenmai, A. K., Bengtström, L., Taxvig, C., Trier, X., Petersen, J. H., Svingen, T., Binderup, M.-L., van Vugt-Lussenburg, B. M. A., Dybdahl, M., Granby, K. & Vinggaard, A. M., 2017, In: Food and Chemical Toxicology. 106, Part A, p. 250-259Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1099 Downloads (Pure) -
Enniatin B and beauvericin are common in Danish cereals and show high hepatotoxicity on a high-content imaging platform
Svingen, T., Hansen, N. L., Taxvig, C., Vinggaard, A. M., Jensen, U. & Rasmussen, P. H., 2017, In: Environmental Toxicology. 32, 5, p. 1658–1664Research output: Contribution to journal › Journal article › Research › peer-review
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Environmental influences on ovarian dysgenesis - developmental windows sensitive to chemical exposures
Johansson, H. K. L., Svingen, T., Fowler, P. A., Vinggaard, A. M. & Boberg, J., 2017, In: Nature Reviews. Endocrinology. 13, p. 400-414Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Mellemkødet sladrer om skadelige kemikalier
Vinggaard, A. M., Svingen, T., Schwartz, C. V. L. & Kjær, C. R., 2017, In: Aktuel Naturvidenskab. 3, p. 12-17Research output: Contribution to journal › Journal article › Research › peer-review
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2016
Fluorinated alkyl substances and technical mixtures used in food paper-packaging exhibit endocrine-related activity in vitro
Rosenmai, A. K., Taxvig, C., Svingen, T., Trier, X., Alice van Vugt-Lussenburg, B. M., Pedersen, M., Lesne, B. & Vinggaard, A. M., 2016, In: Andrology. 4, 4, p. 662-672 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility
Holm, J. B., Mazaud-Guittot, S., Danneskiold-Samsøe, N. B., Chalmey, C., Jensen, B., Nørregård, M. M., Hansen, C. H., Styrishave, B., Svingen, T., Vinggaard, A. M., Koch, H. M., Bowles, J., Koopman, P., Jåégou, B., Kristiansen, K. & Kristensen, D. M., 2016, In: Toxicological Sciences. 150, 1, p. 178-189 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Juvenile Male Rats Exposed to a Low-Dose Mixture of Twenty-Seven Environmental Chemicals Display Adverse Health Effects
Hadrup, N., Svingen, T., Egebjerg, K. M., Skov, K., Pedersen, M., Frederiksen, H., Frandsen, H. L. & Vinggaard, A. M., 2016, In: P L o S One. 11, 9, 22 p., e0162027.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile474 Downloads (Pure) -
Multiple endocrine disrupting effects in rats perinatally exposed to butylparaben
Boberg, J., Petersen, M. A., Svingen, T., Egebjerg, K. M., Christiansen, S., Vinggaard, A. M. & Hass, U., 2016, In: Toxicological Sciences. 152, 1, p. 244-256Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile736 Downloads (Pure) -
Perinatal exposure to mixtures of endocrine disrupting chemicals reduces female rat follicle reserves and accelerates reproductive aging
Johansson, H. K. L., Jacobsen, P. R., Hass, U., Svingen, T., Vinggaard, A. M., Isling, L. K., Axelstad, M., Christiansen, S. & Boberg, J., 2016, In: Reproductive Toxicology. 61, p. 186–194Research output: Contribution to journal › Journal article › Research › peer-review
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SOX9 Regulates Expression of the Male Fertility Gene Ets Variant Factor 5 (ETV5) during Mammalian Sex Development
Alankarage, D., Lavery, R., Svingen, T., Kelly, S., Ludbrook, L., Bagheri-Fam, S., Koopman, P. & Harley, V., 2016, In: The International Journal of Biochemistry & Cell Biology. 79, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2015
Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells
Berg Nygaard, M., Almstrup, K., Lindbæk, L., Christensen, S. T. & Svingen, T., 2015, In: Scientific Reports. 5, 14 p., 10364.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile403 Downloads (Pure) -
Exposure to perfluorononanoic acid combined with a low-dose mixture of 14 human-relevant compounds disturbs energy/lipid homeostasis in rats
Skov, K., Kongsbak, K. G., Hadrup, N., Frandsen, H. L., Svingen, T., Smedsgaard, J., Audouze, K. M. L., Eklund, A. C. & Vinggaard, A. M., 2015, In: Metabolomics. 11, 5, p. 1451-1464 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1
Zhao, L., Svingen, T., Ting Ng, E. & Koopman, P., 2015, In: Development. 142, p. 1-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile588 Downloads (Pure) -
Selection of reference genes for quantitative RT-PCR (RT-qPCR) analysis of rat tissues under physiological and toxicological conditions
Svingen, T., Letting, H., Hadrup, N., Hass, U. & Vinggaard, A. M., 2015, In: PeerJ. 3, 15 p., e855.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile676 Downloads (Pure) -
2014
Expression pattern of clinically relevant markers in paediatric germ cell- and sex-cord stromal tumours is similar to adult testicular tumours
Hammershaimb Mosbech, C., Svingen, T., Nielsen, J. E., Groenkaer Toft, B., Rechnitzer, C., Laub Petersen, B., Rajpert-De Meyts, E. & Engel Hoei-Hansen, C., 2014, (Accepted/In press) In: Virchows Archiv. 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice
Wainwright, E. N., Svingen, T., Ting Ng, E., Wicking, C. & Koopman, P., 2014, In: Developmental Biology. 395, 2, p. 342-354Research output: Contribution to journal › Journal article › Research › peer-review
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Validation of endogenous normalizing genes for expression analyses in adult human testis and germ cell neoplasms
Svingen, T., Jørgensen, A. & Rajpert-De Meyts, E., 2014, (E-pub ahead of print) In: Molecular Human Reproduction. 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Downloads (Pure) -
2013
SOX9 Regulates MicroRNA miR-202-5p/3p Expression During Mouse Testis Differentiation
Wainwright, E. N., Jorgensen, J. S., Kim, Y., Truong, V., Bagheri-Fam, S., Davidson, T., Svingen, T., Fernandez-Valverde, S. L., McClelland, K. S., Taft, R. J., Harley, V. R., Koopman, P. & Wilhelm, D., 2013, In: Biology of Reproduction. 89, 2, p. 1-12 34.Research output: Contribution to journal › Journal article › Research › peer-review
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2012
Loss of Wnt5a Disrupts Primordial Germ Cell Migration and Male Sexual Development in Mice
Chawengsaksophak, K., Svingen, T., Ng, E. T., Epp, T., Spiller, C. M., Clark, C., Cooper, H. & Koopman, P., 2012, In: Biology of Reproduction. 86, 1, p. 1-12 4.Research output: Contribution to journal › Journal article › Research › peer-review
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Three-Dimensional Imaging of Prox1-EGFP Transgenic Mouse Gonads Reveals Divergent Modes of Lymphangiogenesis in the Testis and Ovary
François, M., Koopman, P., Wilhelm, D. & Svingen, T., 2012, In: PLOS ONE. 7, 12, 11 p., e52620.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile104 Downloads (Pure) -
2011
Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice
Kashimada, K., Svingen, T., Feng, C.-W., Pelosi, E., Bagheri-Fam, S., Harley, V. R., Schlessinger, D., Bowles, J. & Koopman, P., 2011, In: F A S E B Journal. 25, 10, p. 3561-3569 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome
Bagheri-Fam, S., Argentaro, A., Svingen, T., Combes, A. N., Sinclair, A. H., Koopman, P. & Harley, V. R., 2011, In: Human Molecular Genetics. 20, 11, p. 2213-2224 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expansion of the Ago gene family in the teleost clade
McFarlane, L., Svingen, T., Braasch, I., Koopman, P., Schartl, M. & Wilhelm, D., 2011, In: Development, Genes and Evolution. 221, 2, p. 95-104 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prokr2-Deficient Mice Display Vascular Dysmorphology of the Fetal Testes: Potential Implications for Kallmann Syndrome Aetiology
Svingen, T., McClelland, K. S., Masumoto, K., Sujino, M., Nagano, M., Shigeyoshi, Y. & Koopman, P., 2011, In: Sexual Development. 5, 6, p. 294-303 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2010
Protein Tyrosine Kinase 2 Beta (PTK2B), but Not Focal Adhesion Kinase (FAK), Is Expressed in a Sexually Dimorphic Pattern in Developing Mouse Gonads
Beverdam, A., Svingen, T., Bagheri-Fam, S., McClive, P., Sinclair, A. H., Harley, V. R. & Koopman, P., 2010, In: Developmental Dynamics. 239, 10, p. 2735-2741 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2009
Ex Vivo Magnetofection: A Novel Strategy for the Study of Gene Function in Mouse Organogenesis
Svingen, T., Wilhelm, D., Combes, A. N., Hosking, B., Harley, V. R., Sinclair, A. H. & Koopman, P., 2009, In: Developmental Dynamics. 238, 4, p. 956-964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of Suitable Normalizing Genes for Quantitative Real-Time RT-PCR Analysis of Gene Expression in Fetal Mouse Gonads
Svingen, T., Spiller, C. M., Kashimada, K., Harley, V. R. & Koopman, P., 2009, In: Sexual Development. 3, 4, p. 194-204 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice
Hosking, B., Francois, M., Wilhelm, D., Orsenigo, F., Caprini, A., Svingen, T., Tutt, D., Davidson, T., Browne, C., Dejana, E. & Koopman, P., 2009, In: Development. 136, 14, p. 2385-2391 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice
Beverdam, A., Svingen, T., Bagheri-Fam, S., Bernard, P., McClive, P., Robson, M., Khojasteh, M. B., Salehi, M., Sinclair, A. H., Harley, V. R. & Koopman, P., 2009, In: Reproduction. 137, 3, p. 481-486 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2008
The Rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development
Daggag, H., Svingen, T., Western, P. S., van den Bergen, J. A., McClive, P. J., Harley, V. R., Koopman, P. & Sinclair, A. H., 2008, In: Biology of Reproduction. 79, 3, p. 468-474 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2007
Aard is specifically up-regulated in Sertoli cells during mouse testis differentiation
Svingen, T., Beverdam, A., Verma, P., Wilhelm, D. & Koopman, P., 2007, In: International Journal of Developmental Biology. 51, 3, p. 255-258 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Involvement of homeobox genes in mammalian sexual development
Svingen, T. & Koopman, P., 2007, In: Sexual Development. 1, 1, p. 12-23 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation
Svingen, T., Beverdam, A., Bernard, P., McClive, P., Harley, V. R., Sinclair, A. H. & Koopman, P., 2007, In: Reproduction. 133, 5, p. 983-989 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2006
Comparative proteomic analysis to study molecular events during gonad development in mice
Wilhelm, D., Huang, E., Svingen, T., Stanfield, S., Dinnis, D. & Koopman, P., 2006, In: Genesis: The Journal of Genetics and Development. 44, 4, p. 168-176 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure
Osborne, S. A., Hawkes, H.-J. K., Baldwin, B. L., Alexander, K. A., Svingen, T., Clarke, F. M. & Tonissen, K. F., 2006, In: Biochemical Journal. 398, Part 2, p. 269-277 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2003
Altered HOX gene expression in human skin and breast cancer cells
Svingen, T. & Tonissen, K., 2003, In: Cancer Biology & Therapy. 2, 5, p. 518-523 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2002
Novel PEX1 mutations and genotype-phenotype correlations in Australasian peroxisome biogenesis disorder patients.
Maxwell, M. A., Allen, T., Solly, P. B., Svingen, T., Paton, B. C. & Crane, D. I., 2002, In: Human Mutation. 20, 5, p. 342-351 10 p.Research output: Contribution to journal › Journal article › Research › peer-review