Publications per year
Publications per year
Personal profile
Profile
Research Area:
My current research focuses on the effects environmental chemicals, particularly mixtures of endocrine disrupting compunds, can have on development and health. With significant background in molecular and developmental biology, I am especially interested in unlocking the molecular mechanism underlying any biological changes and to what degree various compounds can affect normal development and tissue homeostasis. A better understanding of this interphase between the environment and human biology will ultimately aid towards establishing better parameters for human health.
Employment History
Sep 2023 - current: Professor, Head of Research Group - National Food Institute, Technical University of Denmark, Denmark
July 2017 - Aug 2023: Associate Professor, Head of Research Group - National Food Institute, Technical University of Denmark, Denmark
Jun 2014 - Feb 2016: Research Scientist - National Food Institute, Technical University of Denmark, Denmark
Jan 2013 - May 2014: Senior postdoc - Dept. Growth & Reproduction, Copenhagen University Hospital, Denmark
Apr 2005 - Dec 2012: Research Officer - Inst. Molecular Bioscience, The University of Queensland, Australia
Tertiary Education
2001-2005: Doctor of Philosophy (Molecular Biology), Griffith University, Australia
2000-2001: Bachelor of Science with Honours 1st class, Griffith University, Australia
1997-1999: Bachelor of Science (Biotechnology) Griffith University, Australia
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- User defined:
- sex determination
- Endocrine disrupting chemicals
- Mechanisms of endocrine disrupters
- gonad development
- testis, ovary
- reproduction
- testis cancer
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Publications
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AOP Report: An Upstream Network for Reduced Androgen Signaling Leading to Altered Gene Expression of Androgen Receptor–Responsive Genes in Target Tissues
Draskau, M. K., Rosenmai, A. K., Bouftas, N., Johansson, H. K. L., Panagiotou, E. M., Holmer, M. L., Elmelund, E., Zilliacus, J., Beronius, A., Damdimopolou, P., van Duursen, M. & Svingen, T., 2024, (Accepted/In press) In: Environmental Toxicology and Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
Building an adverse outcome pathway network for estrogen-, androgen- and steroidogenesis-mediated reproductive toxicity
Zilliacus, J., Draskau, M. K., Johansson, H. K. L., Svingen, T. & Beronius, A., 2024, In: Frontiers in Toxicology. 6, 17 p., 1357717.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile22 Downloads (Pure) -
Considering life stage and sex when assessing disruption of thyroid hormone synthesis
Rosenmai, A. K., Ramhøj, L., Henriksen, C. S., Rasthøj, J. B., Johansson, H. K., Poulsen, R., Hansen, M. & Svingen, T., 2024, In: Toxicology Letters. 399, Supplement 2, p. S108-S109 2 p., P02-13.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Distinct transcriptional profiles in rat thyroid glands after developmental exposure to three in vitro thyroperoxidase inhibiting chemicals
Rosenmai, A. K., Svingen, T., Evrard, B., Nguyen, K. H., Nielsen, C., Axelstad, M., Chalmel, F. & Ramhøj, L., 2024, In: Genomics. 116, 5, 8 p., 110938.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure) -
Editorial: Endocrine disrupting chemicals in reproductive health, fertility, and early development
De Falco, M., Favetta, L. A., Meccariello, R., Pogrmic-Majkic, K. & Svingen, T., 2024, In: Frontiers in Endocrinology. 15, 3 p., 1478655.Research output: Contribution to journal › Editorial › peer-review
Open AccessFile1 Downloads (Pure)
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MERLON: Merging scientific evidence with regulatory practices and leveraging idenitification of endocrine disruptors using new approach methodologies
Svingen, T. (PI), Axelstad Petersen, M. Z. (CoI), Holmer, M. L. (CoI), Johansson, H. K. L. (CoI), Rosenmai, A. K. (CoI) & Christiansen, S. (Project Manager)
01/01/2024 → 31/12/2028
Project: Research
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Thyroid hormone system disruption: deciphering mechanism of action to improve testing and regulation of endocrine disruptors
Stub, M. H. (PhD Student), Svingen, T. (Main Supervisor) & Ramhøj, L. (Supervisor)
01/06/2023 → 31/05/2026
Project: PhD
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Characterizing the molecular mechanisms underpinninggenital malformations caused bydevelopmental exposure to endocrine disruptors
Elmelund, E. (PhD Student), Svingen, T. (Main Supervisor) & Draskau, M. K. (Supervisor)
01/12/2022 → 30/11/2025
Project: PhD
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PAN: Partnership to develop Adverse Outcome Pathways for endcorine disrupters
Svingen, T. (PI), Rosenmai, A. K. (Project Participant), Draskau, M. K. (Project Participant), Holmer, M. L. (Project Participant), Christiansen, S. (Project Participant), Johansson, H. K. L. (Project Participant), Damdimopoulou, P. (Collaborative Partner), Panagiotou, E. M. (Project Participant), Beronius, A. (Collaborative Partner), Zilliacus, J. (Project Participant), Beatrix Maria van Duursen, M. (Collaborative Partner), Bouftas, N. (Project Participant) & Elmelund, E. (Project Participant)
01/12/2022 → 30/11/2025
Project: Research
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Endocrine disruption across signaling axes:combined effects of endocrine disrupting chemicals withdissimilar modes of action
Strand, I. S. W. (PhD Student), Svingen, T. (Main Supervisor) & Petersen, M. Z. A. (Supervisor)
01/08/2022 → 02/04/2026
Project: PhD
Activities
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Developing an Adverse Outcome Pathway network for reproductive toxicity
Svingen, T. (Invited speaker)
13 Mar 2024Activity: Talks and presentations › Conference presentations
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Reproductive toxicity: Facing challenges with using alternative test methods for predicting adverse outcomes
Svingen, T. (Invited speaker)
15 Apr 2024Activity: Talks and presentations › Conference presentations
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Experimental methods to identify endocrine disruptors affecting reproductive development: opportunities and challenges
Svingen, T. (Invited speaker)
27 Jan 2024Activity: Talks and presentations › Conference presentations
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10th Copenhagen Workshop on Endocrine Disrupters
Svingen, T. (Organizer)
11 Mar 2024 → 14 Mar 2024Activity: Attending an event › Participating in or organising a conference
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MERLON – nyt EU projekt med deltagelse fra CEHOS partnere
Svingen, T. (Speaker)
30 Apr 2024Activity: Talks and presentations › Conference presentations
Press/Media
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Sunde æg- og sædceller er nødvendigt for bæredygtig reproduktion
23/03/2023
1 Media contribution
Press/Media: Press / Media
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Hvorfor plastik?: Mennesket som forsøgskanin
Christiansen, S., Svingen, T. & Johansson, H. K. L.
31/10/2021
1 item of Media coverage
Press/Media: Press / Media
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Har industrialiseringen ødelagt vores fertilitet?
23/06/2021
1 Media contribution
Press/Media: Press / Media
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Håndkøbsmedicin mod svamp kan forstyrre hormonerne
16/06/2021
1 item of Media coverage
Press/Media: Press / Media