Personal profile
Profile
Since February 2013, I have been employed as a senior researcher. I am part of the group "Reproductive toxicology" in the Division of Toxicology and Risk Assessment. This group is led by Professor Ulla Hass. Our overall purpose of our research and public consultancy within this focus area is prevention of reproductive toxicity effects.
I have more than twelve years of experience with large mixture developmental toxicity studies in animals and has special expertise on morphological and functional endpoints such as anogenital distance, malformations, sexual maturation and behaviour. In addition to my research, I do research-based consultancy primarily for the Danish Environmental Protection Agency and Danish Veterinary and Food Administration. I have extensive expertise on evaluations of regulatory studies and the use of in vivo data in REACH and in OECD, where I since 2010 have been one of the two Danish national coordinators within the OECD Test Guideline programme.
Other information
Member of the local organizing committee for ETS conference in 2003. In 2010 she is a large help to the guest editor and president of ETS Ulla Hass. The conference is held in September 2010 in Barcelona. Sofie won a reward in the Annual presentation competition of the Danish Association for Reproduction and Fetal Development with the title: ”A mixture of dissimilarly acting anti-androgens a dangerous cocktail?”International Experience:
Conferences OECD meetings National coordinator for OECD test Guidelines since jan. 2010 Invited speaker
Language Skills:
Danish (Native)
English (Oral & Written)
French (understanding and oral)
Research areas
I have more than twelve years of experience with large mixture developmental toxicity studies in animals and has special expertise on morphological and functional endpoints such as anogenital distance, malformations, sexual maturation and behaviour. In addition to my research, I do research-based consultancy primarily for the Danish Environmental Protection Agency and Danish Veterinary and Food Administration. I have extensive expertise on evaluations of regulatory studies and the use of in vivo data in REACH and in OECD, where I since 2010 have been one of the two Danish national coordinators within the OECD Test Guideline programme.
Education/Academic qualification
PhD Study, Title of thesis: Effects of combined exposure to anti-androgens on development and sexual dimorphic behaviour in rats., DTU Food in collaboration with RUC
2004 → 2009
Ph.D i Toksikologi, RUC
2004 → 2009
CASCADE course in Statistics in risk assessment focusing on dose response modelling
2007
Written and Oral Presentation Skills for Environmental Scientists, Roskilde University
2006
Applied Toxicology, University of Copenhagen
2005
Statistics for Veterinarians, Royal Veterinary and Agricultural University
2005
Laboratory Animal Science, Royal Veterinary and Agricultural University
2004
Biologi, Københavns Universitet
1994 → 2001
External positions
PhD-student, National Food Institute
6 Nov 2001 → …
Keywords
- User defined:
- Reproductive toxicity
- Sexual differentiation
- Endocrine disruption
- Anogenital distance
- Nipple retention
- Mixture effects
- Combination effects
- Behaviour
- Teratology
- Rats
- OECD test guidelines
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Assessing placental transfer and in utero reproductive effects in rats of a short-chained paraffin with in vitro endocrine disrupting properties
Melchiors, M., Rosenmai, A. K., Cariou, R., Pedersen, M., Christiansen, S. & Svingen, T., 2025, In: Current Research in Toxicology. 8, 7 p., 100237.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Downloads (Orbit) -
Editorial - Special issue: Environmental chemicals and the mammary gland
Vandenberg, L. N., Fenton, S. E. & Christiansen, S., 2025, In: Reproductive Toxicology. 138, 2 p., 109062.Research output: Contribution to journal › Editorial › peer-review
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Quantitative analysis of endocrine disruption by ketoconazole and diethylstilbestrol in rat mammary gland development
Montévil, M., Schaeberle, C., Boberg, J., Christiansen, S. & Soto, A. M., 2025, In: Reproductive Toxicology. 135, 13 p., 108929.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of ethanol or ethylene glycol exposure on PPARγ and aromatase expression in adipose tissue
Ardenkjær-Skinnerup, J., Saar, D., Christiansen, S., Svingen, T., Hadrup, N., Brown, K. A., Emanuelli, B., Kragelund, B. B., Ravn-Haren, G. & Vogel, U., 2024, In: Biochemistry and Biophysics Reports. 38, 9 p., 101742.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile362 Downloads (Orbit) -
Enhanced identification of endocrine disruptors through integration of science-based regulatory practices and innovative methodologies: The MERLON Project
Svingen, T., Andersson, A. M., Angelova, J., Axelstad, M., Bakker, J., Baumann, L., Beronius, A., Bouftas, N., Chalmel, F., Christiansen, S., Cornil, C., Damdimopoulou, P., Deepika, D., Dollé, M. E. T., Draskau, M. K., Fischer, M. B., Hagen, C. P., Hessel, E., Holmer, M. L. & Hughes, S. & 20 others, , 2024, In: Open Research Europe. 4, 13 p., 68.Research output: Contribution to journal › Letter › peer-review
Open AccessFile73 Downloads (Orbit)
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MERLON: Merging scientific evidence with regulatory practices and leveraging idenitification of endocrine disruptors using new approach methodologies
Svingen, T. (PI), Petersen, M. Z. A. (CoI), Holmer, M. L. (CoI), Johansson, H. K. L. (CoI), Rosenmai, A. K. (CoI) & Christiansen, S. (Project Manager)
01/01/2024 → 31/12/2028
Project: Research
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PAN: Partnership to develop Adverse Outcome Pathways for endcorine disrupters
Svingen, T. (PI), Rosenmai, A. K. (Project Participant), Draskau, M. K. (Project Participant), Holmer, M. L. (Project Participant), Christiansen, S. (Project Participant), Johansson, H. K. L. (Project Participant), Damdimopoulou, P. (Collaborative Partner), Panagiotou, E. M. (Project Participant), Beronius, A. (Collaborative Partner), Zilliacus, J. (Project Participant), Beatrix Maria van Duursen, M. (Collaborative Partner), Bouftas, N. (Project Participant) & Elmelund, E. (Project Participant)
01/12/2022 → 30/11/2025
Project: Research
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CeHoS: Danish Center for Endocrine Disruptors
Svingen, T. (PI), Andersson, A.-M. (PI), Ebsen Morthorst, J. (PI), Juul, A. (PI), Christiansen, S. (Project Participant), Petersen, M. Z. A. (Project Participant), Holmer, M. L. (Project Participant), Johansson, H. K. L. (Project Participant), Ramhøj, L. (Project Participant), Draskau, M. K. (Project Participant), Rosenmai, A. K. (Project Participant), Elmelund, E. (PhD Student) & Davidsen, N. (Project Participant)
01/06/2022 → 31/12/2025
Project: Research
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ToAD: Improved tools to assess whether biocides and plant protection products have endocrine disrupting properties
Svingen, T. (PI), Wedebye, E. B. (Project Participant), Rosenmai, A. K. (Project Participant), Christiansen, S. (Project Participant), Petersen, M. Z. A. (Project Participant), Ramhøj, L. (Project Participant), Draskau, M. K. (Project Participant) & Melchiors, M. (PhD Student)
01/07/2021 → 30/06/2024
Project: Research
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RA-AOP: The development of Adverse Outcome Pathways on Inhibition of retinol/alcohol dehydrogenase (RDH/ADH) during foetal development leading to urogenital or cardiovascular malformations
Svingen, T. (PI), Bowles, J. (Project Participant), Spiller, C. M. (Project Participant), Draskau, M. K. (Project Participant), Christiansen, S. (Project Participant) & Bech, C. L. (Project Participant)
20/10/2020 → 20/10/2021
Project: Research
Activities
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ED Listen: 23.000 stoffer registreret under REACH - hvilke skal Danmark udpege som hormonforstyrrende?
Christiansen, S. (Guest lecturer)
23 Mar 2023Activity: Talks and presentations › Conference presentations
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FREIA: Test method development for identification of EDCs toxic to female reproduction
Duursen, M. B. M. V. (Other), Lamoree, M. (Other), Gadella, B. M. (Other), Vermeulen, R. (Other), Fowler, P. (Other), Boberg, J. (Other), Wedebye, E. B. (Other), Christiansen, S. (Other), Svingen, T. (Other), Damdimopoulou, P. (Other), Parent, A.-S. (Other), Mazaud-Guittot, S. (Other), Chalmel, F. (Other), Rolland, A. (Other), Connolly, L. (Other), Salumets, A. (Other), Holte, J. (Other) & Soto, A. M. (Other)
28 Jan 2021 → 29 Jan 2021Activity: Talks and presentations › Conference presentations
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Reproductive endocrine disrupting effects of the azole fungicide flusilazole in vitro and in vivo
Draskau, M. K. (Other), Boberg, J. (Other), Taxvig, C. (Other), Pedersen, M. (Other), Frandsen, H. L. (Other), Christiansen, S. (Other) & Svingen, T. (Speaker)
4 Nov 2019 → 8 Nov 2019Activity: Talks and presentations › Conference presentations
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Reproductive effects and mechanisms of action of fetal exposure to azole fungicides
Draskau, M. K. (Other), Boberg, J. (Other), Christiansen, S. (Other) & Svingen, T. (Other)
25 Oct 2018 → 26 Oct 2018Activity: Talks and presentations › Conference presentations
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Reproductive effects and mechanisms of action of fetal exposure to azole fungicides
Draskau, M. K. (Other), Boberg, J. (Other), Christiansen, S. (Other) & Svingen, T. (Other)
8 Nov 2018Activity: Talks and presentations › Conference presentations
Press/Media
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Pesticider fundet i tamponer- Henvist til MST
02/06/2025
1 Media contribution
Press/Media: Press / Media
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Konsekvens af at bisphenol A erstattes med bisphenol S
11/09/2024
1 Media contribution
Press/Media: Press / Media
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