No photo of Søren Nyboe Jakobsen
  • Kemitorvet, 204, 155

    2800 Kgs. Lyngby

    Denmark

20152020
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Research Output 2015 2019

  • 3 Patent
  • 2 Journal article
  • 2 Conference abstract in journal
2019

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

Saini, S. K., Tamhane, T., Anjanappa, R., Saikia, A., Ramskov, S., Donia, M., Svane, I. M., Jakobsen, S. N., Garcia-Alai, M., Zacharias, M., Meijers, R., Springer, S. & Hadrup, S. R., 2019, In : Science Immunology. 4, 37, 13 p., eaau9039.

Research output: Contribution to journalJournal articleResearchpeer-review

TCR engaging antigen-scaffolds for targeted expansion of functionally improved T cells for adoptive cell therapy

Kladis, G., Mindahl, V. R., Tamhane, T., Bentzen, A. K., Donia, M., Svane, I. M., Niessner, H., Sinnberg, T., Garbe, C., Jakobsen, S. N., Schmees, C. & Hadrup, S. R., 2019, In : Annals of Oncology. 30, Supplement_11, 39P .

Research output: Contribution to journalConference abstract in journalResearchpeer-review

2018
139 Downloads (Pure)

Antigen presenting scaffolds for immune-cell manipulation

Hadrup, S. R., Rafa, V. M. & Jakobsen, S. N., 2018, IPC No. A61K39/00, Patent No. WO2018115146 , 28 Jun 2018, Priority date 21 Dec 2016, Priority No. EP20160205918

Research output: Patent

Open Access
File
2017

Peptide-MHC-directed expansion of multifunctional antigen-responsive T cells

Rasmussen, V. M., Marquard, A. M., Jacobsen, S. N. & Hadrup, S. R., 2017, In : Scandinavian Journal of Immunology. 86, 4, p. 344 D-31415.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

2016

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

Bentzen, A. K., Marquard, A. M., Lyngaa, R. B., Saini, S. K., Andersen, S. R., Donia, M., Such, L., Furness, A. J. S., McGranahan, N., Rosenthal, R., Straten, P. T., Szallasi, Z. I., Svane, I. M., Swanton, C., Quezada, S. A., Jakobsen, S. N., Eklund, A. C. & Hadrup, S. R., 2016, In : Nature Biotechnology. 34, 10, p. 1037-1045

Research output: Contribution to journalJournal articleResearchpeer-review

2015
12 Downloads (Pure)

Determining antigen recognition through barcoding of mhc multimers

Reker Hadrup, S., Pedersen, H., Jakobsen, S. & Bentzen, A. K., 10 Dec 2015, IPC No. G01N 33/ 569 A I, Patent No. WO2015185067, 6 Jun 2014, Priority date 6 Jun 2014, Priority No. DK2014PA70340

Research output: Patent

Open Access
File
54 Downloads (Pure)

General detection and isolation of specific cells by binding of labeled molecules

Pedersen, H., Jakobsen, S., Hadrup, S. R., Bentzen, A. K. & Johansen, K. H., 17 Dec 2015, IPC No. G01N 33/ 533 A I, Patent No. WO2015188839, 6 Jan 2015, Priority date 16 Aug 2014, Priority No. DK2014PA00453

Research output: Patent

Open Access
File