• Kemitorvet, 220, 427D

    2800 Kgs. Lyngby

    Denmark

1977 …2021

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The major research interest of the past 10 years has been microbial biofilms in relation to cell-cell interactions and developmental processes. The knowledge obtained in the course of this work is now being further developed in connection with detailed studies of microbial adaptation and evolution in cases of chronic infections. These current research activities are based on the assumption that fundamental studies of bacteria physiology and ecology are essential if we wish to understand and eventually interfere with such microbial infections. The investigations employ several methods providing global information about the cells’ genomes and functional genomics. In particular, specific clones of bacteria infecting airways of cystic fibrosis patients are studied. In connection with these studies evolution of antibiotic resistance is an important topic where the current focus point is resistance mechanisms involved in tolerance to anti-microbial peptides. Development of various types of laboratory model systems for simulation of human infections in vitro has been added to the research program.

 



Expertise related to UN Sustainable Devlopment Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 2 - Zero Hunger
  • SDG 3 - Good Health and Well-being
  • SDG 12 - Responsible Consumption and Production
  • SDG 14 - Life Below Water

Keywords

  • User defined:
  • Biofilms, chronic infections, functional genomics, evolution, antibiotic resistance, bacterial physiology

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