If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Journal article
2019

Metabolic and regulatory insights from the experimental Horizontal Gene Transfer of the aurofusarin and bikaverin gene clusters to Aspergillus nidulans

de Reus, E., Nielsen, M. R. & Frandsen, R. J. N., 2019, In : Molecular Microbiology. 112, 6, p. 1684-1700 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2018

Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans

Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, K. T., Nafisi, M., Kannangara, R. M., Stærk, D., Okkels, F. T., Binderup, K., Madsen, B., Møller, B. L., Thrane, U. & Mortensen, U. H., 2018, In : Scientific Reports. 8, 1

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
270 Downloads (Pure)

Identification of the decumbenone biosynthetic gene cluster in Penicilliuum decumbens and the importance for production of calbistrin

Grijseels, S., Pohl, C., Nielsen, J. C., Wasil, Z., Nygård, Y., Nielsen, J., Frisvad, J. C., Nielsen, K. F., Workman, M., Larsen, T. O., Driessen, A. J. M. & Frandsen, R. J. N., 2018, In : Fungal Biology and Biotechnology. 5, 17 p., 18.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
189 Downloads (Pure)

On the biosynthetic origin of carminic acid

Rasmussen, S. A., Kongstad, K. T., Khorsand-Jamal, P., Kannangara, R. M., Nafisi, M., Van Dam, A., Bennedsen, M., Madsen, B., Okkels, F., Gotfredsen, C. H., Stærk, D., Thrane, U., Mortensen, U. H., Larsen, T. O. & Frandsen, R. J. N., 2018, In : Insect Biochemistry and Molecular Biology. 96, p. 51-61 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
328 Downloads (Pure)
2017

Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

Kannangara, R., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, K. T., Stærk, D., Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, B. L., 2017, In : Nature Communications. 8, 1, 12 p., 1987 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
263 Downloads (Pure)

Gene expression plasticity across hosts of an invasive scale insect species

Christodoulides, N., Van Dam, A., Peterson, D. A., Frandsen, R. J. N., Mortensen, U. H., Petersen, B., Rasmussen, S., Normark, B. B. & Hardy, N. B., 2017, In : P L o S One. 12, 5, 13 p., e0176956.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
247 Downloads (Pure)

Physiological characterization of secondary metabolite producing Penicillium cell factories

Grijseels, S., Nielsen, J., Nielsen, J., Larsen, T. O., Frisvad, J. C., Nielsen, K. F., Frandsen, R. J. N. & Workman, M., 2017, In : Fungal Biology and Biotechnology. 4, 8, 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
412 Downloads (Pure)

Synthesis of C-Glucosylated Octaketide Anthraquinones in Nicotiana benthamiana by Using a Multispecies-Based Biosynthetic Pathway

Andersen-Ranberg, J., Kongstad, K. T., Nafisi, M., Stærk, D., Okkels, F. T., Mortensen, U. H., Møller, B. L., Frandsen, R. J. N. & Kannangara, R., 2017, In : Chembiochem. 18, 19, p. 1893-1897

Research output: Contribution to journalJournal articleResearchpeer-review

2016

Black perithecial pigmentation in Fusarium species is due to the accumulation of 5-deoxybostrycoidin-based melanin

Frandsen, R. J. N., Rasmussen, S. A., Knudsen, P. B., Uhlig, S., Petersen, D., Lysøe, E., Gotfredsen, C. H., Giese, H. & Larsen, T. O., 2016, In : Scientific Reports. 6, 13 p., 26206.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
319 Downloads (Pure)

Draft genome sequence and chemical profiling of Fusarium langsethiae, an emerging producer of type A trichothecenes

Lysøe, E., Frandsen, R. J. N., Divon, H. H., Terzi, V., Orrù, L., Lamontanara, A., Kolseth, A. K., Nielsen, K. F. & Thrane, U., 2016, In : International Journal of Food Microbiology. 221, p. 29-36 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2015

Combining Stable Isotope Labeling and Molecular Networking for Biosynthetic Pathway Characterization

Klitgaard, A., Nielsen, J. B., Frandsen, R. J. N., Andersen, M. R. & Nielsen, K. F., 2015, In : Analytical Chemistry. 87, 13, p. 6520-6526 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Combining UHPLC-High Resolution MS and Feeding of Stable Isotope Labeled Polyketide Intermediates for Linking Precursors to End Products

Klitgaard, A., Frandsen, R. J. N., Holm, D. K., Knudsen, P. B., Frisvad, J. C. & Nielsen, K. F., 2015, In : Journal of Natural Products. 78, 7, p. 1518-1525 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Expression profiling and functional analyses of BghPTR2, a peptide transporter from Blumeria graminis f. sp. hordei

Droce, A., Holm, K. B., Olsson, S., Frandsen, R. J. N., Sondergaard, T. E., Sørensen, J. L. & Giese, H., 2015, In : Fungal Biology. 119, 7, p. 551-559 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Heterologous expression of MlcE in Saccharomyces cerevisiae provides resistance to natural and semi-synthetic statins

Ley, A., Coumou, H. C. & Frandsen, R. J. N., 2015, In : Metabolic Engineering Communications. 2, p. 117-123 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
306 Downloads (Pure)
2014

Fusarium graminearum PKS14 is involved in orsellinic acid and orcinol synthesis

Jørgensen, S. H., Frandsen, R. J. N., Nielsen, K. F., Lysøe, E., Sondergaard, T. E., Wimmer, R., Giese, H. & Sørensen, J. L., 2014, In : Fungal Genetics and Biology. 70, p. 24-31 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
855 Downloads (Pure)

Genetic transformation of Fusarium avenaceum by Agrobacterium tumefaciens mediated transformation and the development of a USER-Brick vector construction system

Sorensen, L. Q., Lysøe, E., Larsen, J. E., Khorsand-Jamal, P., Nielsen, K. F. & Frandsen, R. J. N., 2014, In : B M C Molecular Biology. 15, 1, 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
291 Downloads (Pure)

The Genome of the Generalist Plant Pathogen Fusarium avenaceum Is Enriched with Genes Involved in Redox, Signaling and Secondary Metabolism.

Lysøe, E., Harris, L. J., Walkowiak, S., Subramaniam, R., Divon, H. H., Riiser, E. S., Llorens, C., Gabaldón, T., Kistler, H. C., Jonkers, W., Kolseth, A-K., Nielsen, K. F., Thrane, U. & Frandsen, R. J. N., 2014, In : P L o S One. 9, 11, 17 p., e112703.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
223 Downloads (Pure)
2013

Phylogenetic analyses of RPB1 and RPB2 support a middle Cretaceous origin for a clade comprising all agriculturally and medically important fusaria

O’Donnell, K., Rooney, A. P., Proctor, R. H., Brown, D. W., McCormick, S. P., Ward, T. J., Frandsen, R. J. N., Lysøe, E., Rehner, S. A., Aoki, T., Robert, V. A. R. G., Crous, P. W., Groenewald, J. Z., Kang, S. & Geiser, D. M., 2013, In : Fungal Genetics and Biology. 52, p. 20-31

Research output: Contribution to journalJournal articleResearchpeer-review

Reconstruction of the biosynthetic pathway for the core fungal polyketide scaffold rubrofusarin in Saccharomyces cerevisiae

Rugbjerg, P., Naesby, M., Mortensen, U. H. & Frandsen, R. J. N., 2013, In : Microbial Cell Factories. 12, 1, 9 p., 31.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
203 Downloads (Pure)

The Effect of Nanosilver on Pigments Production by Fusarium culmorum (W. G. Sm.) Sacc.

Kasprowicz, M. J., Gorczyca, A. & Frandsen, R. J. N., 2013, In : Polish Journal of Microbiology. 62, 4, p. 365-372

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Genetics of Polyketide Metabolism in Aspergillus nidulans

Klejnstrup, M. L., Frandsen, R. J. N., Holm, D. K., Nielsen, M. T., Mortensen, U. H., Larsen, T. O. & Nielsen, J. B., 2012, In : Metabolites. 2, 1, p. 100-133

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
442 Downloads (Pure)

Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum

Sørensen, J. L., Hansen, F. T., Sondergaard, T. E., Staerk, D., Lee, T. V., Wimmer, R., Klitgaard, L. G., Purup, S., Giese, H. & Frandsen, R. J. N., 2012, In : Environmental Microbiology. 14, 5, p. 1159-1170

Research output: Contribution to journalJournal articleResearchpeer-review

Quick guide to polyketide synthase and nonribosomal synthetase genes in Fusarium

Hansen, J. T., Sørensen, J. L., Giese, H., Sondergaard, T. E. & Frandsen, R. J. N., 2012, In : International Journal of Food Microbiology. 155, 3, p. 128-136

Research output: Contribution to journalJournal articleResearchpeer-review

Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum

Frandsen, R. J. N., Schütt, C., Lund, B. W., Staerk, D., Nielsen, J., Olsson, S. & Giese, H., 2011, In : Journal of Biological Chemistry. 286, 12, p. 10419-10428

Research output: Contribution to journalJournal articleResearchpeer-review

2 Downloads (Pure)
2010

A pre-processing strategy for liquid chromatography time-of-flight mass spectrometry metabolic fingerprinting data

Nielsen, N. J., Tomasi, G., Frandsen, R. J. N., Kristensen, M. B., Nielsen, J., Giese, N. H. & Christensen, J. H., 2010, In : Metabolomics. 6, 3, p. 341-352

Research output: Contribution to journalJournal articleResearchpeer-review

Development of pollution-induced community tolerance is linked to structural and functional resilience of a soil bacterial community following a five-year field exposure to copper

Brandt, K. K., Frandsen, R. J. N., Holm, P. E. & Nybroe, O., 2010, In : Soil Biology & Biochemistry. 42, 5, p. 748-757

Research output: Contribution to journalJournal articleResearchpeer-review

Methylenetetrahydrofolate Reductase Activity Is Involved in the Plasma Membrane Redox System Required for Pigment Biosynthesis in Filamentous Fungi

Frandsen, R. J. N., Albertsen, K. S., Stougaard, P., Sørensen, J. L., Nielsen, K. F., Olsson, S. & Giese, H., 2010, In : Eukaryotic Cell (Online Edition). 9, 8, p. 1225-1235

Research output: Contribution to journalJournal articleResearchpeer-review

2008

Efficient four fragment cloning for the construction of vectors for targeted gene replacement in filamentous fungi

Frandsen, R. J. N., Andersson, J. A., Kristensen, M. B. & Giese, H., 2008, In : BMC Molecular Biology. 9, p. 70

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
226 Downloads (Pure)
2006

The biosynthetic pathway for aurofusarin in Fusarium graminearum reveals a close link between the naphthoquinones and naphthopyrones

Frandsen, R. J. N., Nielsen, N. J., Maolanon, N., Sørensen, J. C., Olsson, S., Nielsen, J. & Giese, N. H., 2006, In : Molecular Microbiology. 61, 4, p. 1069-1080

Research output: Contribution to journalJournal articleResearchpeer-review

The PKS4 gene in Fusarium graminearum is essential for zearalenone production.

Lysøe, E., Klemsdal, S. S., Bone, K. R., Frandsen, R. J. N., Johansen, T., Thrane, U. & Giese, H., 2006, In : Applied and Environmental Microbiology. 72, 6, p. 3924-3932

Research output: Contribution to journalJournal articleResearchpeer-review