Publications per year
Publications per year
Personal profile
Profile
I am a scientist in the reproduction toxicology group. We carry out toxicological studies on rats exposed to endocrine disruptors during development, after which the effects on their reproductive- and nervous system are assessed. Since we know that people are exposed to low doses of multiple endocrine disruptors simultaneously, the endocrine disrupting chemicals are tested both individually and in combination.
My primary work lies within the planning and execution of these toxicology studies, and subsequent data processing and statistical analysis. In the experiments we investigate the offspring during their whole life cycle, and my expert areas include: study of animal semen quality, and behavioral studies. My PhD project dealt with exposure to endocrine disruptors that affect the thyroid hormone system, and here I have tested a widely used pesticide and a common UV filter for endocrine disrupting effects. Besides my research, I advise the Danish EPA on endocrine disrupters and the Danish Veterinary and Food Administration on caffeine.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD in toxicology, National Food Institute, Technical University of Denmark
2006 → 2010
M.Sc. in Biology, University of Copenhagen
1995 → 2002
External positions
PhD student, National Food Institute, Technical University of Denmark
2006 → 2010
research assistant, National Food Institute, Technical University of Denmark
2003 → 2006
Keywords
- User defined:
- Reproductive toxicity
- Endocrine disrupters
- Combination effects
- Behavioral studies
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Enhanced identification of endocrine disruptors through integration of science-based regulatory practices and innovative methodologies: The MERLON Project
Svingen, T., Andersson, A. M., Angelova, J., Axelstad, M., Bakker, J., Baumann, L., Beronius, A., Bouftas, N., Chalmel, F., Christiansen, S., Cornil, C., Damdimopoulou, P., Deepika, D., Dollé, M. E. T., Draskau, M. K., Fischer, M. B., Hagen, C. P., Hessel, E., Holmer, M. L. & Hughes, S. & 20 others, , 2024, In: Open Research Europe. 4, 13 p., 68.Research output: Contribution to journal › Letter › peer-review
Open AccessFile4 Downloads (Pure) -
Revealing hidden challenges: an in-depth evaluation of Anogenital Distance (AGD) and Areola/Nipple Retention (NR) assessments in EOGRT Studies, with implications for regulatory toxicology
Axelstad, M., Hass, U., Bichlmaier, I., Simanainen, U., Beausoleil, C., Deweirdt, J., Bergkvist, C. & Christiansen, S., 2024, In: Toxicology Letters. 399, Supplement 2, p. S374 1 p., LP-26.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Two thyroperoxidase-inhibiting chemicals induce shared transcriptional changes in hippocampus of developing rats
Ramhøj, L., Svingen, T., Evrard, B., Chalmel, F. & Axelstad, M., 2024, In: Toxicology. 505, 9 p., 153822.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile18 Downloads (Pure) -
Benzophenone-3: Comprehensive review of the toxicological and human evidence with meta-analysis of human biomonitoring studies
Mustieles, V., Balogh, R. K., Axelstad, M., Montazeri, P., Márquez, S., Vrijheid, M., Draskau, M. K., Taxvig, C., Peinado, F. M., Berman, T., Frederiksen, H., Fernández, M. F., Vinggaard, A. M. & Andersson, A.-M., 2023, In: Environment International. 173, 26 p., 107739.Research output: Contribution to journal › Review › peer-review
Open AccessFile419 Downloads (Pure) -
Corrigendum to "PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes" [Environ. Pollut. 305 (2022) 119340]
Davidsen, N., Ramhøj, L., Lykkebo, C. A., Kugathas, I., Poulsen, R., Rosenmai, A. K., Evrard, B., Darde, T. A., Axelstad, M., Bahl, M. I., Hansen, M., Chalmel, F., Licht, T. R. & Svingen, T., 2023, In: Environmental Pollution. 317, 5 p., 120709.Research output: Contribution to journal › Comment/debate › Research › peer-review
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MERLON: Merging scientific evidence with regulatory practices and leveraging idenitification of endocrine disruptors using new approach methodologies
Svingen, T. (PI), Axelstad Petersen, M. Z. (CoI), Holmer, M. L. (CoI), Johansson, H. K. L. (CoI), Rosenmai, A. K. (CoI) & Christiansen, S. (Project Manager)
01/01/2024 → 31/12/2028
Project: Research
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Endocrine disruption across signaling axes:combined effects of endocrine disrupting chemicals withdissimilar modes of action
Strand, I. S. W. (PhD Student), Svingen, T. (Main Supervisor) & Petersen, M. Z. A. (Supervisor)
01/08/2022 → 02/04/2026
Project: PhD
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CeHoS: Danish Center for Endocrine Disruptors
Svingen, T. (PI), Andersson, A.-M. (PI), Ebsen Morthorst, J. (PI), Juul, A. (PI), Christiansen, S. (Project Participant), Axelstad Petersen, M. Z. (Project Participant), Holmer, M. L. (Project Participant), Johansson, H. K. L. (Project Participant), Ramhøj, L. (Project Participant), Draskau, M. K. (Project Participant), Rosenmai, A. K. (Project Participant), Elmelund, E. (PhD Student) & Davidsen, N. (Project Participant)
01/06/2022 → 31/12/2025
Project: Research
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PARC: Partnership for the Assessment of Risks from Chemicals
Svingen, T. (PI), Wedebye, E. B. (PI), Pires, S. M. (PI), Vinggaard, A. M. (PI), Beltoft, V. M. (Project Manager), Ramhøj, L. (Project Participant), Houmark Stub, M. (PhD Student), Nikolov, N. G. (Project Participant), Nissen, A. C. V. E. (Project Participant) & Axelstad Petersen, M. Z. (Project Participant)
01/05/2022 → 30/04/2029
Project: Research
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PARC T5.2.1c: New approach methods to improve human health risk assessment of thyroid hormone system disruption
Svingen, T. (PI), Ramhøj, L. (Project Participant), Axelstad Petersen, M. Z. (Project Participant) & Houmark Stub, M. (PhD Student)
01/05/2022 → 30/04/2026
Project: Research
Activities
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Hormonforstyrrende stoffers effekt på hjernens udvikling -søgen efter sensitive markører
Axelstad Petersen, M. Z. (Guest lecturer)
23 Mar 2023Activity: Talks and presentations › Conference presentations
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Environmental disruptions of the thyroid hormone axis
Ramhøj, L. (Invited speaker), Petersen, M. A. (Other) & Svingen, T. (Other)
5 Sept 2020 → 9 Sept 2020Activity: Talks and presentations › Conference presentations
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Diminished serum T4 concentrations induced by PTU or brominated flame retardants (DE-71) are necessary but not sufficient for a congenital malformation of the brain
Ramhøj, L. (Speaker), Kortenkamp, A. (Other), Scholze, M. (Other), Köhrle, J. (Other), Svingen, T. (Other) & Petersen, M. A. (Other)
30 Oct 2019 → 3 Nov 2019Activity: Talks and presentations › Conference presentations
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Rats as a classical model to study environmental disruption of the thyroid hormone axis – ‘heterotopia’ as a novel biomarker?
Ramhøj, L. (Invited speaker), Kortenkamp, A. (Other), Scholze, M. (Other), Svingen, T. (Other), Köhrle, J. (Other) & Petersen, M. A. (Other)
26 Jun 2019 → 27 Jun 2019Activity: Talks and presentations › Conference presentations
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Combination effects of pesticides on birth weight and metabolic programming in rat offspring
Svingen, T. (Invited speaker), Ramhøj, L. (Other), Petersen, M. A. (Other), Christiansen, S. (Other), Scholze, M. (Other), Boberg, J. (Other), Vinggaard, A. M. (Other) & Hass, U. (Other)
24 Jan 2018 → 25 Jan 2018Activity: Talks and presentations › Conference presentations
Press/Media
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Corona: Alt laboratoriearbejde på DTU sat i bero
25/03/2020
1 item of Media coverage
Press/Media: Press / Media
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Scientists back thyroid measurements for EDC identification following criticism
Christiansen, S. & Petersen, M. A.
23/09/2019
1 item of Media coverage
Press/Media: Press / Media
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Findes i madkasser og drikkedunke: Kemikalie kan skade drenges ordforråd
25/01/2019
1 item of Media coverage
Press/Media: Press / Media
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Men hvor usunde er de koffeinholdige drikke egentlig?
20/06/2017
1 item of Media coverage
Press/Media: Press / Media
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