Photo of Magnus Karlsson
  • Ørsteds Plads, 349, 114

    2800 Kgs. Lyngby

    Denmark

19992020

Research output per year

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Research Output

2020

Analysis of dDNP NMR metabolic data from cancer cells

Frahm, A. B., Lundsgaard, E., Matei, A., Jensen, P. R., Karlsson, M., Ardenkjær-Larsen, J. H. & Lerche, M. H., 2020. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
150 Downloads (Pure)

Bayesian filtering framework for noise characterization of frequency combs

Brajato, G., Lundberg, L., Torres-Company, V., Karlsson, M. & Zibar, D., 27 Apr 2020, In : Optics Express. 28, 9, p. 13949-13964

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
31 Downloads (Pure)

Detection of myocardial medium-chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1-13C]octanoate

Yoshihara, H. A. I., Bastiaansen, J. A. M., Karlsson, M., Lerche, M. H., Comment, A. & Schwitter, J., 2020, In : NMR in Biomedicine. 33, 3, 8 p., e4243.

Research output: Contribution to journalJournal articleResearchpeer-review

Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

Kampmeyer, C., Johansen, J. V., Holmberg, C., Karlson, M., Gersing, S. K., Bordallo, H. N., Kragelund, B. B., Lerche, M. H., Jourdain, I., Winther, J. R. & Hartmann-Petersen, R., 2020, In : ACS Synthetic Biology. 9, 4, p. 733-748

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Gadolinium Effect at High-Magnetic-Field DNP: 70% 13C Polarization of [U-13C] Glucose Using Trityl

Capozzi, A., Patel, S., Wenckebach, W. T., Karlsson, M., Lerche, M. H. & Ardenkjær-Larsen, J. H., 2019, In : Journal of Physical Chemistry Letters. 10, p. 3420-3425

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
16 Downloads (Pure)

Rapid zero-trans kinetics of Cs+ exchange in human erythrocytes quantified by dissolution hyperpolarized 133Cs+ NMR spectroscopy

Kuchel, P. W., Karlsson, M., Lerche, M. H., Shishmarev, D. & Ardenkjær-Larsen, J. H., 2019, In : Scientific Reports. 9, 1, 12 p., 19726.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
41 Downloads (Pure)

Real-Time Detection of Intermediates in Rhodium Catalyzed Hydrogenation of Alkynes and Alkenes by Dissolution DNP

Boeg, P. A., Duus, J. Ø., Ardenkjær-Larsen, J. H., Karlsson, M. & Mossin, S., 2019, In : The Journal of Physical Chemistry Part C. 123, 15, p. 9949-9956 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
38 Downloads (Pure)

Targeted Metabolomics with Quantitative Dissolution Dynamic Nuclear Polarization

Lerche, M. H., Karlsson, M., Ardenkjær-Larsen, J. H. & Jensen, P. R., 2019, NMR-Based Metabolomics. Gowda, G. & Raftery, D. (eds.). Springer, p. 385-393 (Methods in Molecular Biology, Vol. 2037).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2018

Analysis of dDNP NMR metabolic data from cancer cells (- poster)

Frahm, A. B., Lundsgaard, E. A., Matei, A., Jensen, P. R., Karlsson, M., Ardenkjær-Larsen, J. H. & Lerche, M. H., 2018. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
95 Downloads (Pure)

A narrow line UV-induced non-persistent radical to generate highly polarized transportable glucose solid samples

Capozzi, A., Patel, S., Ouari, O., Karlsson, M., Lerche, M. H., Comment, A. & Ardenkjær-Larsen, J. H., 2018. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
142 Downloads (Pure)

Efficient Hyperpolarization of U-13 C-Glucose Using Narrow-Line UV-Generated Labile Free Radicals

Capozzi, A., Patel, S., Gunnarsson, C. P., Marco-Rius, I., Comment, A., Karlsson, M., Lerche, M. H., Ouari, O. & Ardenkjær-Larsen, J. H., 2018, In : ANGEWANDTE CHEMIE. 57, p. 1 – 6

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
65 Downloads (Pure)

Liquid-State 13C Polarization of 30% through Photoinduced Nonpersistent Radicals

Capozzi, A., Karlsson, M., Petersen, J. R., Lerche, M. H. & Ardenkjær-Larsen, J. H., 2018, In : Journal of Physical Chemistry C. 122, 13, p. 7432-7443

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
150 Downloads (Pure)

Liquid-State Polarization of 30% through Photo-Induced Non-Persistent Radicals on 13C Pyruvic Acid

Capozzi, A., Karlsson, M., Petersen, J. R., Lerche, M. H. & Ardenkjær-Larsen, J. H., 2018. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
100 Downloads (Pure)
2017

A narrow line UV-induced non-persistent radical in view of generating highly polarized transportable glucose solid samples

Capozzi, A., Coi, A., Patel, S., Ouari, O., Karlsson, M., Lerche, M. H., Comment, A. & Ardenkjær-Larsen, J. H., 2017. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearch

Open Access
File
165 Downloads (Pure)

dDNP as an emergent real time analytical method for catalytic reactions

Boeg, P. A., Mossin, S., Duus, J. Ø., Ardenkjær-Larsen, J. H. & Karlsson, M., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
41 Downloads (Pure)

dDNP as an emerging real time analytical method for catalytic reactions

Boeg, P. A., Mossin, S., Duus, J. Ø., Ardenkjær-Larsen, J. H. & Karlsson, M., 2017. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
79 Downloads (Pure)
Open Access
File
269 Downloads (Pure)

Hyperpolarized 133Cs is a sensitive probe for real-time monitoring of biophysical environments

Karlsson, M., Ardenkjær-Larsen, J. H. & Lerche, M. H., 2017, In : Chemical Communications. 53, 49, p. 6625-6628 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
202 Downloads (Pure)

Measuring glucose cerebral metabolism in the healthy mouse using hyperpolarized C-13 magnetic resonance

Mishkovsky, M., Anderson, B., Karlsson, M., Lerche, M. H., Sherry, A. D., Gruetter, R., Kovacs, Z. & Comment, A., 2017, In : Scientific Reports. 7, 1, 8 p., 11719.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
251 Downloads (Pure)

Preparation of Radical-Free Hyperpolarized Water using Photo-induced non-persistent Radicals on a “SpinLab-like” dissolution-DNP Polarizer

Capozzi, A., Coi, A., Karlsson, M., Lerche, M. H. & Ardenkjær-Larsen, J. H., 2017. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
244 Downloads (Pure)

Quantifying Biochemical Activities in Living Cells with 13C dDNP NMR

Jensen, P. R., Karlsson, M., Capozzi, A., Ardenkjær-Larsen, J. H. & Lerche, M. H., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
29 Downloads (Pure)
2016
20 Downloads (Pure)

High-field dissolution dynamic nuclear polarization of [1-13C]pyruvic acid

Yoshihara, H. A. I., Can, E., Karlsson, M., Lerche, M. H., Schwitter, J. & Comment, A., 2016, In : Physical Chemistry Chemical Physics. 18, 18, p. 12409-12413

Research output: Contribution to journalJournal articleResearchpeer-review

Hyperpolarized 1-13c-1,1-bis(acetoxy(methyl))-2,2'-cyclopropane as metabolic marker for mr

Lerche, M. H., Jensen, P. R., Karlsson, M., Napolitano, R., Cabella, C., Miragoli, L., Colombo Serra, S. & Tedoldi, F., 11 May 2016, IPC No. A61K 49/ 10 A I, Patent No. EP3016687, 8 Jan 2015, Priority date 30 Jun 2014, Priority No. WO2014EP63842

Research output: Patent

Open Access
File
94 Downloads (Pure)

Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-13C]glutamine

Jensen, P. R., Canape, C., Catanzaro, G., Karlsson, M. & Lerche, M. H., 2016. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
179 Downloads (Pure)
Open Access
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187 Downloads (Pure)
2015

3D metabolic ex vivo sample imaging of hyperpolarized compounds using a 3D single-shot RARE (3D SS-RARE) sequence, combining spectral RF selectivity with under-sampled spectral encoding at signal read-out

Magnusson, P. O., Jensen, P. R., Dyrby, T. B., Karlsson, M., Lerche, M. H. & Hanson, L. G., 2015, Proceedings of 5th hyperpolarization symposium. p. 105 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
87 Downloads (Pure)

Hyperpolarized [1,3-C-13(2)]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer

Jensen, P. R., Serra, S. C., Miragoli, L., Karlsson, M., Cabella, C., Poggi, L., Venturi, L., Tedoldi, F. & Lerche, M. H., 2015, In : International Journal of Cancer. 136, 4, p. E117-E126

Research output: Contribution to journalJournal articleResearchpeer-review

Hyperpolarized 2-oxoglutarate as metabolic agent in mr

Jensen, P. R., Karlsson, M., Lerche, M. H., Cabella, C., Caminiti, L., Colombo Serra, S., Miragoli, L., Poggi, L., Venturi, L. & Tedoldi, F., 2 Sep 2015, IPC No. A61K 49/ 10 A I, Patent No. EP2911704, 2 Sep 2015, Priority date 24 Oct 2013, Priority No. WO2013EP72269

Research output: Patent

Open Access
File
86 Downloads (Pure)

Hyperpolarized amino acids

Karlsson, M., Lerche, M. H. & Jensen, P. R., 11 Feb 2015, IPC No. A61K 49/ 10 A I, Patent No. EP2833924, 11 Feb 2015, Priority date 28 Mar 2013, Priority No. WO2013EP56696

Research output: Patent

Open Access
File
52 Downloads (Pure)

Hyperpolarized esters as metabolic markers in mr

Jensen, P. R., Lerche, M. H., Karlsson, M., Cabella, C., Colombo Serra, S., Miragoli, L., Venturi, L. & Tedoldi, F., 9 Dec 2015, IPC No. A61K 49/ 10 A I, Patent No. EP2950826, 9 Dec 2015, Priority date 30 Jan 2014, Priority No. EP20140704304

Research output: Patent

Open Access
File
55 Downloads (Pure)

Intra-operative cancer diagnosis based on a hyperpolarized marker

Lerche, M. H., Karlsson, M. & Jensen, P. R., 18 Mar 2015, IPC No. G01N 33/ 574 A I, Patent No. EP2847591, 18 Mar 2015, Priority date 7 May 2013, Priority No. WO2013EP59481

Research output: Patent

Open Access
File
43 Downloads (Pure)

Myocardial fatty acid metabolism probed with hyperpolarized [1-13C]octanoate

Yoshihara, H., Bastiaansen, J. A., Karlsson, M., Lerche, M. H., Comment, A. & Schwitter, J., 2015, In : Journal of Cardiovascular Magnetic Resonance. 17, Suppl. 1, p. 1-2

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
95 Downloads (Pure)

NMR Insights into the Inner Workings of Living Cells

Lerche, M. H., Jensen, P. R., Karlsson, M. & Meier, S., 2015, In : Analytical chemistry. 87, p. 119−132

Research output: Contribution to journalJournal articleResearchpeer-review

Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-C-13]glutamine: Glutaminolysis to Measure Drug Response in Cancer Cells

Canape, C., Catanzaro, G., Terreno, E., Karlsson, M., Lerche, M. H. & Jensen, P. R., 2015, In : Magnetic Resonance in Medicine. 73, 6, p. 2296-2305

Research output: Contribution to journalJournal articleResearchpeer-review

Triarylmethyl radicals.

Karlsson, M., Napolitano, R., Visigalli, M., Lerche, M. H., Jensen, P. R. & Tedoldi, F., 20 May 2015, IPC No. G01R 33/ 62 A I, Patent No. EP2872520, 20 May 2015, Priority date 4 Jul 2013, Priority No. WO2013EP64121

Research output: Patent

Open Access
File
38 Downloads (Pure)
2014

Hyperpolarized NMR Probes for Biological Assays

Meier, S., Jensen, P. R., Karlsson, M. & Lerche, M. H., 2014, In : Sensors. 14, 1, p. 1576-1597

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
94 Downloads (Pure)

Non-invasive in-cell determination of free cytosolic [NAD+]/ [NADH] ratios using hyperpolarized glucose show large variations in metabolic phenotypes

Christensen, C. E., Karlsson, M., Winther, J. R., Jensen, P. R. & Lerche, M. H., 2014, In : Journal of Biological Chemistry. 289, 4, p. 2344-2352

Research output: Contribution to journalJournal articleResearchpeer-review

Process for the preparation of hyperpolarized derivatives for use in mri analysis

Aime, S., Battista Giovenzana, G., Tedoldi, F., Jensen, P. R., Karlsson, M., Lerche, M. H. & Colombo Serra, S., 20 Aug 2014, IPC No. A61K 49/ 10 A I, Patent No. EP2766050, 20 Aug 2014, Priority date 11 Oct 2012, Priority No. WO2012EP70187

Research output: Patent

Open Access
File
45 Downloads (Pure)
2013

Composition comprising acetic anhydride and a gadolinium complex, and method for the use in hyperpolarisation mri analysis.

Lerche, M. H., Karlsson, M., Jensen, P. R., Colombo Serra, S., Visigalli, M., Aime, S. & Tedoldi, F., 13 Jun 2013, IPC No. A61K 49/ 10 A I, Patent No. WO2013083535, 13 Jun 2013, Priority date 5 Dec 2011, Priority No. EP20110191872

Research output: Patent

Open Access
File
42 Downloads (Pure)

In vivo and in vitro liver cancer metabolism observed with hyperpolarized [5-C-13]glutamine

Cabella, C., Karlsson, M., Canape, C., Catanzaro, G., Serra, S. C., Miragoli, L., Poggi, L., Uggeri, F., Venturi, L., Jensen, P. R., Lerche, M. H. & Tedoldi, F., 2013, In : Journal of Magnetic Resonance. 232, p. 45-52

Research output: Contribution to journalJournal articleResearchpeer-review

N-15-Permethylated amino acids as efficient probes for MRI-DNP applications

Chiavazza, E., Viale, A., Karlsson, M. & Aime, S., 2013, In : Contrast Media & Molecular Imaging. 8, 5, p. 417-421

Research output: Contribution to journalJournal articleResearchpeer-review

Process for preparing hyperpolarized substrates and method for mri

Aime, S., Battista Giovenzana, G., Tedoldi, F., Maiocchi, A., Uggeri, F., Jensen, P. R., Karlsson, M., Lerche, M. H., Visigalli, M., Crosetti, M. & Poggi, L., 13 Feb 2013, IPC No. A61K 49/ 10 A I, Patent No. EP2555803, 13 Feb 2013, Priority date 8 Apr 2011, Priority No. WO2011EP55485

Research output: Patent

Open Access
File
52 Downloads (Pure)
2012

Development of Dissolution DNP-MR Substrates for Metabolic Research

Karlsson, M., Jensen, P. R., Duus, J. Ø., Meier, S. & Lerche, M. H., 2012, In : Applied Magnetic Resonance. 43, 1-2, p. 223-236

Research output: Contribution to journalJournal articleResearchpeer-review

Hyperpolarized 13C-labelled anhydrides as DNP precursors of metabolic MRI agents

Serra, S. C., Karlsson, M., Giovenzana, G. B., Cavallotti, C., Tedoldi, F. & Aime, S., 2012, In : Contrast Media & Molecular Imaging. 7, 5, p. 469-477

Research output: Contribution to journalJournal articleResearchpeer-review

2011

A hyperpolarized choline molecular probe for monitoring acetylcholine synthesis

Allouche-Arnon, H., Gamliel, A., Barzilay, C. M., Nalbandian, R., Gomori, J. M., Karlsson, M., Lerche, M. H. & Katz-Brull, R., 2011, In : Contrast Media & Molecular Imaging. 6, 3, p. 139-147

Research output: Contribution to journalJournal articleResearchpeer-review

Detection of tumor glutamate metabolism in vivo using 13C magnetic resonance spectroscopy and hyperpolarized [1- 13C]glutamate

Gallagher, F. A., Kettunen, M. I., Day, S. E., Hu, D. E., Karlsson, M., Gisselsson, A., Lerche, M. H. & Brindle, K. M., 2011, In : Magnetic Resonance in Medicine. 66, 1, p. 18-23

Research output: Contribution to journalJournal articleResearchpeer-review

Deuteration of a molecular probe for DNP hyperpolarization - a new approach and validation for choline chloride

Allouche-Arnon, H., Lerche, M. H., Karlsson, M., Lenkinski, R. E. & Katz-Brull, R., 2011, In : Contrast Media & Molecular Imaging. 6, 6, p. 499-506

Research output: Contribution to journalJournal articleResearchpeer-review

Metabolic pathway visualization in living yeast by DNP-NMR

Meier, S., Karlsson, M., Jensen, P. R., Lerche, M. H. & Duus, J. Ø., 2011, In : Molecular BioSystems. 7, 10, p. 2834-2836

Research output: Contribution to journalJournal articleResearchpeer-review