Research output per year
Research output per year
Personal profile
Profile
With hyperpolarization techniques NMR signals of many different nuclei can be temporarily boosted with several orders of magnitudes. Dissolution DNP (dDNP) is one such hyperpolarization technique which has great versatility with respect to the hyperpolarization target (molecules or ions). My interest lies in developing applications for dDNP in biological and purely chemical systems with the aim of revealing new insights into metabolic or chemical pathways and kinetics. I’m also interested in expanding the field of dDNP by developing applications for nuclei other than 13C or 1H that are the most commonly employed in dDNP applications or investigations.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Chemical absorption of carbon dioxide in non-aqueous systems using the amine 2-amino-2-methyl-1-propanol in dimethyl sulfoxide and N-methyl-2-pyrrolidone
Karlsson, H. K., Makhool, H., Karlsson, M. & Svensson, H., 2021, In: Separation and Purification Technology. 256, 9 p., 117789.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile155 Downloads (Pure) -
Metabolic contrast agents produced from transported solid 13C-glucose hyperpolarized via dynamic nuclear polarization
Capozzi, A., Kilund, J., Karlsson, M., Patel, S., Pinon, A. C., Vibert, F., Ouari, O., Lerche, M. H. & Ardenkjaer-Larsen, J. H., 2021, In: Communications Chemistry. 4, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Downloads (Pure) -
Analysis of dDNP NMR metabolic data from cancer cells
Frahm, A. B., Lundsgaard, E., Matei, A., Jensen, P. R., Karlsson, M., Ardenkjær-Larsen, J. H. & Lerche, M. H., 2020. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Open AccessFile261 Downloads (Pure) -
Detection of myocardial medium-chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1-13C]octanoate
Yoshihara, H. A. I., Bastiaansen, J. A. M., Karlsson, M., Lerche, M. H., Comment, A. & Schwitter, J., 2020, In: NMR in Biomedicine. 33, 3, 8 p., e4243.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Downloads (Pure) -
Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water
Kampmeyer, C., Johansen, J. V., Holmberg, C., Karlson, M., Gersing, S. K., Bordallo, H. N., Kragelund, B. B., Lerche, M. H., Jourdain, I., Winther, J. R. & Hartmann-Petersen, R., 2020, In: ACS Synthetic Biology. 9, 4, p. 733-748Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile72 Downloads (Pure)
Projects
- 3 Finished
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Metabolomics using Dissolution DNP-NMR
Frahm, A., Lerche, M. H., Jensen, P. R., Karlsson, M., Elena-Herrmann, B. & Giraudeau, P.
01/01/2018 → 12/08/2021
Project: PhD
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Chemical reactions and intermediates followed by DNP NMR
Boeg, P. A., Mossin, S., Ardenkjær-Larsen, J. H., Duus, J. Ø., Meier, S., Skrydstrup, T., Theis, T. & Karlsson, M.
01/12/2015 → 19/08/2019
Project: PhD
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dDNP as a method to assess altered cellular metabolism in vitro
Malinowski, R. M., Ardenkjær-Larsen, J. H., Duus, J. Ø., Jensen, P. R., Karlsson, M., Giraudeau, P. & Sriram, R.
01/05/2015 → 23/01/2019
Project: PhD
Activities
- 3 Conference presentations
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Quantifying Biochemical Activities in Living Cells with 13C dDNP NMR
Mathilde Hauge Lerche (Invited speaker), Magnus Karlsson (Other), Jan Henrik Ardenkjær-Larsen (Other), Pernille Rose Jensen (Other) & Andrea Capozzi (Other)
24 Jul 2017Activity: Talks and presentations › Conference presentations
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Preparation of Radical-Free Hyperpolarized Water using Photo-induced non-persistent Radicals on a “SpinLab-like” dissolution-DNP Polarize
Andrea Capozzi (Speaker), Alessandro Coi (Panel member), Magnus Karlsson (Panel member), Mathilde Hauge Lerche (Guest lecturer) & Jan Henrik Ardenkjær-Larsen (Guest lecturer)
2 Jul 2017 → 6 Jul 2017Activity: Talks and presentations › Conference presentations
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A narrow line UV-induced non-persistent radical in view of generating highly polarized transportable glucose solid samples
Andrea Capozzi (Guest lecturer), Alessandro Coi (Panel member), S Patel (Panel member), Olivier Ouari (Panel member), Magnus Karlsson (Guest lecturer), Mathilde Hauge Lerche (Guest lecturer), Arnaud Comment (Panel member) & Jan Henrik Ardenkjær-Larsen (Panel member)
2 Jul 2017 → 6 Jul 2017Activity: Talks and presentations › Conference presentations
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