Lise Marie Grav

Assistant Professor, Department of Biotechnology and Biomedicine
Visiting Scientist/ Professor, Novo Nordisk Foundation Center for Biosustainability
CHO Cell Line Engineering and Design

Kemitorvet, 220, 506F
2800 Kgs. Lyngby
Denmark

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11 Journal article
1 Ph.D. thesis
1 Book chapter

Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells
Shin, S., Kim, S. H., Shin, S. W., Grav, L. M., Pedersen, L. E., Lee, J. S. & Lee, G. M., 2020, In : ACS Synthetic Biology. 9, 6, p. 1263-1269
Research output: Contribution to journal › Journal article › Research › peer-review
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
Gutierrez, J. M., Feizi, A., Li, S., Kallehauge, T. B., Hefzi, H., Grav, L. M., Ley, D., Baycin Hizal, D., Betenbaugh, M. J., Voldborg, B. G., Kildegaard, H. F., Min Lee, G., Palsson, B. O., Nielsen, J. & Lewis, N. E., 2020, In : Nature Communications. 11, 1, 68.
Research output: Contribution to journal › Journal article › Research › peer-review

Open Access
File
70 Downloads (Pure)
Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells
Sergeeva, D., Min Lee, G., Nielsen, L. K. & Grav, L. M., 2020, In : ACS Synthetic Biology. 9, 9, p. 2546-2561
Research output: Contribution to journal › Journal article › Research › peer-review
BCAT1 and BCAT2 disruption in CHO cells has cell line-dependent effects
Pereira, S., Ley, D., Schubert, M., Grav, L. M., Kildegaard, H. F. & Andersen, M. R., 2019, In : Journal of Biotechnology. 306, p. 24-31
Research output: Contribution to journal › Journal article › Research › peer-review
Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering
Pristovšek, N., Nallapareddy, S., Grav, L. M., Hefzi, H., Lewis, N. E., Rugbjerg, P., Hansen, H. G., Lee, G. M., Andersen, M. R. & Kildegaard, H. F., 2019, In : ACS Synthetic Biology. 8, 4, p. 758-774 17 p.
Research output: Contribution to journal › Journal article › Research › peer-review

1 Active
3 Finished

Oligoclonal recombinant antivenom production through co-culture
Adams, A. C., Nielsen, L. K., Laustsen, A. H. & Grav, L. M.
15/01/2020 → 23/04/2023
Project: PhD
CHO cell line engineering for improved production of challenging therapeutic proteins
Sergeeva, D., Nielsen, L. K., Min Lee, G., Jensen, M. K., James, D. C., Tolstrup, A. B. & Grav, L. M.
Fonde
01/09/2017 → 25/01/2021
Project: PhD
Accelerated and rational design of improved CHO cell factories for production of biopharmaceuticals
Grav, L. M., Lee, J. S., Andersen, M. R. & Kildegaard, H. F.
01/12/2014 → 30/11/2017
Project: Research
Accelerated and rational design of Improved CHO Cell factories
Grav, L. M., Kildegaard, H. F., Lee, J. S., Jensen, M. K., Kaas, C. S., Otte, K. & Andersen, M. R.
Offentlig finansiering
01/12/2014 → 18/04/2018
Project: PhD