Research output per year
Research output per year
Personal profile
Profile
My bioinformatics research is centred around development and application of machine learning methodology for studying the interplay between the cellular level human immune system and disease phenotypes. The application of my research aims to facilitate bio marker discovery and aid in developing patient specific treatment.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Research output
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NetTCR-2.0 enables accurate prediction of TCR-peptide binding by using paired TCRα and β sequence data
Montemurro, A., Schuster, V., Povlsen, H. R., Bentzen, A. K., Jurtz, V., Chronister, W. D., Crinklaw, A., Hadrup, S. R., Winther, O., Peters, B., Jessen, L. E. & Nielsen, M., 2021, In: Communications Biology. 4, 1, 13 p., 1060.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Downloads (Pure) -
Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study
Özgümüş, T., Sulaieva, O., Jessen, L. E., Jain, R., Falhammar, H., Nyström, T., Catrina, S. B., Jörneskog, G., Groop, L., Eliasson, M., Eliasson, B., Brismar, K., Stokowy, T., Nilsson, P. M. & Lyssenko, V., 2021, In: Scientific Reports. 11, 1, 11 p., 20735.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Downloads (Pure) -
TCRMatch: Predicting T-Cell Receptor Specificity Based on Sequence Similarity to Previously Characterized Receptors
D. Chronister, W., Crinklaw, A., Mahajan, S., Vita, R., Koşaloğlu-Yalçın, Z., Yan, Z., A. Greenbaum, J., Jessen, L. E., Nielsen, M., Christley, S., G. Cowell, L., Sette, A. & Peters, B., 2021, In: Frontiers in Immunology. 12, 10 p., 640725.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile68 Downloads (Pure) -
Conference Report: Why R? 2019
Burdukiewicz, M., Pietluch, F., Chilimoniuk, J., Sidorczuk, K., Rafacz, D., Jessen, L. E., Roediger, S., Kosinski, M. & Wojcik, P., 2020, In: The R Journal. 12, 1, p. 484-494Research output: Contribution to journal › Journal article › Communication
Open AccessFile6 Downloads (Pure) -
Immunopeptidomic Data Integration to Artificial Neural Networks Enhances Protein-Drug Immunogenicity Prediction
Barra, C., Ackaert, C., Reynisson, B., Schockaert, J., Jessen, L. E., Watson, M., Jang, A., Comtois-Marotte, S., Goulet, J-P., Pattijn, S., Paramithiotis, E. & Nielsen, M., 2020, In: Frontiers in Immunology. 11, 13 p., 1304.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile66 Downloads (Pure)
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Integrative Single-Cell Analysis for Exploring Autoimmune Disease Mechanisms
Drachmann, C., Jessen, L. E. & Kristensen, L. E.
01/03/2022 → 28/02/2025
Project: PhD
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Improved Immunoinformatic Methods for Rationale T Cell Epitope Discovery
Montemurro, A., Nielsen, M. & Jessen, L. E.
01/10/2019 → 30/09/2022
Project: PhD
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Development of Immunoinformatics prediction methods for improved rational identification of T cell epitopes
Povlsen, H. R., Nielsen, M. & Jessen, L. E.
01/04/2019 → 31/07/2022
Project: PhD
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Towards accurate prediction of T cell targets; Learning the rules of T cell receptor interactions
Nielsen, M., Jessen, L. E. & Hadrup, S. R.
01/08/2017 → 31/07/2020
Project: Research
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Optimizing and Broadening the Breadth of a VAR2CSA DBL4 Based Placental Malaria Vaccine by in silico Sequence Analysis
Jessen, L. E., Hviid, L., Petersen, T. N., Kesmir, C., Tolstrup, N. & Lund, O.
Technical University of Denmark
01/05/2010 → 04/06/2014
Project: PhD