Research output per year
Research output per year
- 25 results
Search results
-
2025
Machine learning uncovers the transcriptional regulatory network for the production host Streptomyces albidoflavus
Jönsson, M., Sigrist, R., Gren, T., Semenov Petrov, M., Marcussen, N. E. J., Svetlova, A., Charusanti, P., Gockel, P., Palsson, B. O., Yang, L. & Özdemir, E., 2025, In: Cell Reports. 44, 3, 115392.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Downloads (Orbit) -
2024
A growth selection system for sucrose synthases (SuSy): design and test
Bidart, G. N., Hyeuk, S., Alter, T. B., Yang, L. & Welner, D. H., 2024, In: AMB Express. 14, 1, 70.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile26 Downloads (Orbit) -
Meta-analysis Driven Strain Design for Mitigating Oxidative Stresses Important in Biomanufacturing
Phaneuf, P. V., Kim, S. H., Rychel, K., Rode, C., Beulig, F., Palsson, B. O. & Yang, L., 2024, In: ACS Synthetic Biology. 13, 7, p. 2045-2059Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Downloads (Orbit) -
Repeated glucose oscillations in high cell-density cultures influence stress-related functions of Escherichia coli
Bafna-Rührer, J., Bhutada, Y. D., Orth, J. V., Øzmerih, S., Yang, L., Zielinski, D. & Sudarsan, S., 2024, In: Pnas Nexus. 3, 9, pgae376.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile15 Downloads (Orbit) -
2023
Recording Microbial Signals In Soil: Developing Genetic Memory Devices For Detection Of Specialized Metabolites In Microbiomes
Hansen, M. L., Nørgaard, J.-J. K., Yang, L. & Jelsbak, L., 2023, The Danish Microbiological Society Annual Congress 2023: Abstract book. Danish Microbiological Society, p. 71-71 1 p. 69Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review
Open AccessFile55 Downloads (Orbit) -
2022
Identification and Engineering of Transporters for Efficient Melatonin Production in Escherichia coli
Yang, L., Malla, S., Özdemir, E., Kim, S. H., Lennen, R., Christensen, H. B., Christensen, U., Munro, L. J., Herrgård, M. J., Kell, D. B. & Palsson, B., 2022, In: Frontiers in Microbiology. 13, 10 p., 880847.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile111 Downloads (Orbit) -
2021
Escherichia coli Data-Driven Strain Design Using Aggregated Adaptive Laboratory Evolution Mutational Data
Phaneuf, P. V., Zielinski, D. C., Yurkovich, J. T., Johnsen, J., Szubin, R., Yang, L., Kim, S. H., Schulz, S., Wu, M., Dalldorf, C., Ozdemir, E., Lennen, R. M., Palsson, B. O. & Feist, A. M., 2021, In: ACS Synthetic Biology. 10, 12, p. 3379–3395 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile210 Downloads (Orbit) -
2020
Directed Metabolic Pathway Evolution Enables Functional Pterin-Dependent Aromatic-Amino-Acid Hydroxylation in Escherichia coli
Luo, H., Yang, L., Kim, S. H., Wulff, T., Feist, A. M., Herrgard, M. & Palsson, B., 2020, In: ACS Synthetic Biology. 9, 3, p. 494-499Research output: Contribution to journal › Journal article › Research › peer-review
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Engineered cells for production of indole-derivatives
Kell, D. (Inventor), Yang, L. (Inventor) & Malla, S. (Inventor), 24 Sept 2020, IPC No. C07K 14/ 715 A I, Patent No. WO2020187739, 13 Mar 2020, Priority date 15 Mar 2019, Priority No. EP20190163184Research output: Patent
Open AccessFile261 Downloads (Orbit) -
Microbial Synthesis of Human-Hormone Melatonin at Gram Scales
Luo, H., Schneider, K., Christensen, U., Lei, Y., Herrgard, M. & Palsson, B. Ø., 2020, In: ACS Synthetic Biology. 9, 6, p. 1240-1245 6 p.Research output: Contribution to journal › Letter › peer-review
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2019
Coupling S-adenosylmethionine-dependent methylation to growth: Design and uses
Luo, H., Hansen, A. S. L., Yang, L., Schneider, K., Kristensen, M., Christensen, U., Christensen, H. B., Du, B., Özdemir, E., Feist, A. M., Keasling, J. D., Jensen, M. K., Herrgård, M. J. & Palsson, B. O., 2019, In: PLOS Biology. 17, 3, e2007050.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile491 Downloads (Orbit) -
Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli
Jindal, S., Yang, L., Day, P. J. & Kell, D. B., 2019, In: BMC Microbiology. 19, 1, 16 p., 195.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile248 Downloads (Orbit) -
2016
Within-Host Evolution of the Dutch High-Prevalent Pseudomonas aeruginosa Clone ST406 during Chronic Colonization of a Patient with Cystic Fibrosis
Van Mansfeld, R., De Been, M., Paganelli, F., Yang, L., Bonten, M. & Willems, R., 2016, In: P L o S One. 11, 6, 22 p., e0158106.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile456 Downloads (Orbit) -
2013
Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts
Pedersen, S. D., Yang, L., Molin, S. & Jelsbak, L., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 19, p. 7766-7771Research output: Contribution to journal › Journal article › Research › peer-review
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2012
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.
Folkesson, A., Jelsbak, L., Yang, L., Johansen, H. K., Ciofu, O., Høiby, N. & Molin, S., 2012, In: Nature Reviews. Microbiology. 10, 12, 841 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Downloads (Orbit) -
Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection
Hansen, S. K., Rau, M. H., Johansen, H. K., Ciofu, O., Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, K., von Buchwald, C., Høiby, N. & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31Research output: Contribution to journal › Journal article › Research › peer-review
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2011
Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data
Yang, L., Rau, M. H., Yang, L., Høiby, N., Molin, S. & Jelsbak, L., 2011, In: B M C Microbiology. 11, p. 184Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile356 Downloads (Orbit) -
Evolutionary dynamics of bacteria in a human host environment
Yang, L., Jelsbak, L., Marvig, R. L., Pedersen, S. D., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, H. K., Ciofu, O., Høiby, N., Sommer, M. & Molin, S., 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-7486Research output: Contribution to journal › Journal article › Research › peer-review
1 Downloads (Orbit) -
Microbial ecology and adaptation in cystic fibrosis airways
Yang, L., Jelsbak, L. & Molin, S., 2011, In: Environmental Microbiology. 13, 7, p. 1682-1689Research output: Contribution to journal › Journal article › Research › peer-review
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2010
Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts
Rau, M. H., Hansen, S. K., Johansen, H. K., Thomsen, L. E., Workman, C., Nielsen, K. F., Jelsbak, L., Høiby, N., Yang, L. & Molin, S., 2010, In: Environmental Microbiology. 12, 6, p. 1643-1658Research output: Contribution to journal › Journal article › Research › peer-review
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Functional Genetic Mapping of Pheudomonas Aeruginosa from Cystic Fibrosis Lungs
Yang, L., Aug 2010, Kgs. Lyngby, Denmark: Technical University of Denmark.Research output: Book/Report › Ph.D. thesis
Open AccessFile4488 Downloads (Orbit) -
2008
In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections
Yang, L., Haagensen, J. A. J., Jelsbak, L., Johansen, H. K., Sternberg, C., Høiby, N. & Molin, S., 2008, In: Journal of Bacteriology. 190, 8, p. 2767-2776Research output: Contribution to journal › Journal article › Research › peer-review
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2007
Antimicrobial activities of YycG histidine kinase inhibitors against Staphylococcus epidermidis biofilms
Qin, Z., Lee, B. L. R., Yang, L., Zhang, J., Yang, X., Qu, D., Jiang, H. & Molin, S., 2007, In: F E M S Microbiology Letters. 273, 2, p. 149-56Research output: Contribution to journal › Journal article › Research › peer-review
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Formation and properties of in vitro biofilms of ica-negative Staphylococcus epidermidis clinical isolates
Qin, Z., Yang, X., Yang, L., Jiang, J., Ou, Y., Molin, S. & Qu, D., 2007, In: Journal of Medical Microbiology. 56, p. 83-93Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients
Jelsbak, L., Johansen, H. K., Frost, A. L. V., Thøgersen, R., Thomsen, L. E., Ciofu, O., Yang, L., Haagensen, J. A. J., Høiby, N. & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-2224Research output: Contribution to journal › Journal article › Research › peer-review