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2020

Recurrent tuberculosis in patients infected with the predominant Mycobacterium tuberculosis outbreak strain in Denmark. New insights gained through whole genome sequencing

Folkvardsen, D. B., Norman, A., Rasmussen, E. M., Lillebaek, T., Jelsbak, L. & Andersen, Å. B., 2020, In : Infection, Genetics and Evolution. 80, 6 p., 104169.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

A rare thioquinolobactin siderophore present in a bioactive Pseudomonas sp. DTU12.1

Sazinas, P., Hansen, M. L., Aune, M. I., Fischer, M. H. & Jelsbak, L., 2019, In : Genome Biology and Evolution. 11, 12, p. 3529-3533 5 p., evz267.

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Complete Genome Sequence of a Bioactive Pseudomonas sp. Strain, DTU12.3, Isolated from Soil in Denmark

Sazinas, P., Aune, M. I., Fischer, M. H., Lauritsen, J. G., Gram, L. & Jelsbak, L., 2019, In : Microbiology Resource Announcements. 8, 16, 2 p., e00121-19.

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Within-host adaptation mediated by intergenic evolution in Pseudomonas aeruginosa

Khademi, S. M. H., Sazinas, P. & Jelsbak, L., 2019, In : Genome Biology and Evolution. 11, 5, p. 1385-1397 13 p., evz083.

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2018

A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations: Exploring gene profile virulence explanations

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Lillebaek, T. & Jelsbak, L., 2018, In : Scientific Reports. 8, 8 p., 11869.

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131 Downloads (Pure)

HldE Is Important for Virulence Phenotypes in Enterotoxigenic Escherichia coli

Maigaard Hermansen, G. M., Boysen, A., Krogh, T. J., Nawrocki, A., Jelsbak, L. & Møller-Jensen, J., 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 253, 13 p., 253.

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Intergenic evolution during host adaptation increases expression of the metallophore pseudopaline in Pseudomonas aeruginosa

Hermansen, G. M. M., Hansen, M. L., Khademi, S. M. H. & Jelsbak, L., 2018, In : Microbiology. 164, 8, p. 1038-1047

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Transcriptomic profiling of interacting nasal staphylococci species reveals global changes in gene and non-coding RNA expression

Hermansen, G. M. M., Sazinas, P., Kofod, D., Millard, A., Andersen, P. S. & Jelsbak, L., 2018, In : FEMS Microbiology Letters. 365, 5, 9 p., fny004.

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2017

Genomic epidemiology of a major Mycobacterium tuberculosis outbreak: Retrospective cohort study in a low incidence setting using sparse time-series sampling

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Jelsbak, L. & Lillebaek, T., 2017, In : Journal of Infectious Diseases. 216, 3, 19 p.

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Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

Bartell, J., Blazier, A. S., Yen, P., Thøgersen, J. C., Jelsbak, L., Goldberg, J. B. & Papin, J. A., 2017, In : Nature Communications. 8, 13 p., 14631.

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SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

Lauridsen, R. K., Madsen Sommer, L. M., Johansen, H. K., Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, S. B. & Boisen, A., 2017, In : Scientific Reports. 7, 7 p., 45264.

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237 Downloads (Pure)
2016

A Bacteriophage-Acquired O-Antigen Polymerase (Wzyβ) from P. aeruginosa Serotype O16 Performs a Varied Mechanism Compared to Its Cognate Wzyα

Taylor, V. L., Hoage, J. F. J., Thrane, S. W., Huszczynski, S. M., Jelsbak, L. & Lam, J. S., 2016, In : Frontiers in Microbiology. 7, 15 p., 393.

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Antibiotic combination therapy can select for broad-spectrum multidrug resistance in Pseudomonas aeruginosa

Vestergaard, M., Paulander, W., Marvig, R. L., Clasen, J., Jochumsen, N., Molin, S., Jelsbak, L., Ingmer, H. & Folkesson, S. A., 2016, In : International Journal of Antimicrobial Agents. 47, p. 48-55 8 p.

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1009 Downloads (Pure)

Application of WGS data for O-specific antigen analysis and in silico serotyping of Pseudomonas aeruginosa isolates

Thrane, S. W., Taylor, V. L., Lund, O., Lam, J. S. & Jelsbak, L., 2016, In : Journal of Clinical Microbiology. 54, 7, p. 1782-1788 7 p.

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Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

Frydenlund Michelsen, C., Khademi, S. M. H., Johansen, H. K., Ingmer, H., Dorrestein, P. C. & Jelsbak, L., 2016, In : I S M E Journal. 10, p. 1323-1336 14 p.

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Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate

Norman, A., Ciofu, O., Amador Hierro, C. I., Høiby, N. & Jelsbak, L., 2016, In : Genome Announcements. 4, 1, 2 p., e00008-16.

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Wang, M., Carver, J. J., Pevzner, P., Mohiman, H., Bandeira, N., Phelan, V. V., Sanchez, L. M., Garg, N., Watrous, J., Luzzatto-Knaa, T., Frydenlund Michelsen, C., Jelsbak, L., Månsson, M., Klitgaard, A. & Nielsen, K. F., 2016, In : Nature Biotechnology. 34, 8, p. 828-837 10 p.

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Substantial molecular evolution and mutation rates in prolonged latent Mycobacterium tuberculosis infection in humans

Lillebaek, T., Norman, A., Rasmussen, E. M., Marvig, R. L., Bek Folkvardsen, D., Bengaard Andersen, Å. & Jelsbak, L., 2016, In : International Journal of Medical Microbiology. 306, 7, p. 580-585 6 p.

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The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions

Jochumsen, N., Marvig, R. L., Pedersen, S. D., Jensen, R. L., Paulander, W., Molin, S., Jelsbak, L. & Folkesson, A., 2016, In : Nature Communications. 7, 10 p., 13002.

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The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

Wassermann, T., Meinike Jørgensen, K., Ivanyshyn, K., Bjarnsholt, T., Khademi, S. M. H., Jelsbak, L., Høiby, N. & Ciofu, O., 2016, In : Microbiology. 162, 5, p. 865-875 11 p.

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Utilization and control of ecological interactions in polymicrobial infections and community-based microbial cell factories

Wigneswaran, V., Amador Hierro, C. I., Jelsbak, L., Sternberg, C. & Jelsbak, L., 2016, In : F1000Research. 5, 7 p., 421.

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2015

Bacteriocin-mediated competition in cystic fibrosis lung infections

Ghoul, M., West, S. A., Johansen, H. K., Molin, S., Harrison, O. B., Maiden, M. C. J., Jelsbak, L., Bruce, J. B. & Griffin, A. S., 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1814, 8 p., 20150972.

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Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

Freschi, L., Jeukens, J., Kukavica-Ibrulj, I., Boyle, B., Dupont, M-J., Laroche, J., Larose, S., Maaroufi, H., Fothergill, J. L., Moore, M., Jelsbak, L. & Thrane, S. W., 2015, In : Frontiers in Microbiology. 6, 8 p., 1036.

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Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

Marvig, R. L., Madsen Sommer, L. M., Jelsbak, L., Molin, S. & Johansen, H. K., 2015, In : Future Microbiology. 10, 4, p. 599-611 13 p.

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The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015, In : mBio (Online). 6, 5, 10 p., e01396-15.

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2014

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa.

Markussen, T., Marvig, R. L., Gómez Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., 2014, In : mBio (Online). 5, 5, p. e01592-e01514

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Staphylococcus aureus Alters Growth Activity, Autolysis, and Antibiotic Tolerance in a Human Host-Adapted Pseudomonas aeruginosa Lineage.

Frydenlund Michelsen, C., Christensen, A-M., Bojer, M. S., Høiby, N., Ingmer, H. & Jelsbak, L., 2014, In : Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

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Within-host evolution of Pseudomonas aeruginosa reveals adaptation toward iron acquisition from hemoglobin.

Marvig, R. L., Pedersen, S. D., Khademi, S. M. H., Markussen, T., Molin, S. & Jelsbak, L., 2014, In : mBio (Online). 5, 3, e00966-14.

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Archetypal analysis of diverse Pseudomonas aeruginosa transcriptomes reveals adaptation in cystic fibrosis airways

Thøgersen, J. C., Mørup, M., Pedersen, S. D., Molin, S. & Jelsbak, L., 2013, In : BMC Bioinformatics. 14, 1, p. 279

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Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

Marvig, R. L., Jochumsen, N., Johansen, H. K., Høiby, N., Molin, S., Sommer, M., Jelsbak, L. & Folkesson, A., 2013, In : Genome Announcements. 1, 5, 2 p., e00804-13.

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Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

Pedersen, S. D., Yang, L., Molin, S. & Jelsbak, L., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 19, p. 7766-7771

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Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators.

Marvig, R. L., Johansen, H. K., Molin, S. & Jelsbak, L., 2013, In : P L o S Genetics. 9, 9, e1003741.

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Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison)

Salomonsen, C. M., Themudo, G. E., Jelsbak, L., Molin, S., Høiby, N. & Hammer, A. S., 2013, In : Veterinary Microbiology. 163, 1-2, p. 103-109

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2012

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.

Folkesson, A., Jelsbak, L., Yang, L., Johansen, H. K., Ciofu, O., Høiby, N. & Molin, S., 2012, In : Nature Reviews. Microbiology. 10, 12, 841 p.

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1 Downloads (Pure)

Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment

Rau, M. H., Marvig, R. L., Ehrlich, G. D., Molin, S. & Jelsbak, L., 2012, In : Environmental Microbiology. 14, 8, p. 2200-2211

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Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

Hansen, S. K., Rau, M. H., Johansen, H. K., Ciofu, O., Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, K., von Buchwald, C., Høiby, N. & Molin, S., 2012, In : I S M E Journal. 6, 1, p. 31

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Multilocus Sequence Typing of Total-Genome-Sequenced Bacteria

Larsen, M. V., Cosentino, S., Rasmussen, S., Rundsten, C. F., Hasman, H., Marvig, R. L., Jelsbak, L., Sicheritz-Pontén, T., Ussery, D. W., Aarestrup, F. M. & Lund, O., 2012, In : Journal of Clinical Microbiology. 50, 4, p. 1355-1361

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3 Downloads (Pure)

Mutations in 23S rRNA Confer Resistance against Azithromycin in Pseudomonas aeruginosa

Marvig, R. L., Søndergaard, M. S. R., Pedersen, S. D., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., 2012, In : Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521

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1 Downloads (Pure)
2011

Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

Yang, L., Rau, M. H., Yang, L., Høiby, N., Molin, S. & Jelsbak, L., 2011, In : B M C Microbiology. 11, p. 184

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Evolutionary dynamics of bacteria in a human host environment

Yang, L., Jelsbak, L., Marvig, R. L., Pedersen, S. D., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, H. K., Ciofu, O., Høiby, N., Sommer, M. & Molin, S., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-7486

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Microbial ecology and adaptation in cystic fibrosis airways

Yang, L., Jelsbak, L. & Molin, S., 2011, In : Environmental Microbiology. 13, 7, p. 1682-1689

Research output: Contribution to journalJournal articleResearchpeer-review

2010

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

Rau, M. H., Hansen, S. K., Johansen, H. K., Thomsen, L. E., Workman, C., Nielsen, K. F., Jelsbak, L., Høiby, N., Yang, L. & Molin, S., 2010, In : Environmental Microbiology. 12, 6, p. 1643-1658

Research output: Contribution to journalJournal articleResearchpeer-review

2008

In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

Yang, L., Haagensen, J. A. J., Jelsbak, L., Johansen, H. K., Sternberg, C., Høiby, N. & Molin, S., 2008, In : Journal of Bacteriology. 190, 8, p. 2767-2776

Research output: Contribution to journalJournal articleResearchpeer-review

2007

Complete genome sequence of the myxobacterium Sorangium cellulosum

Schneiker, S., Perlova, O., Kaiser, O., Gerth, K., Alici, A., Altmeyer, MO., Bartels, D., Bekel, T., Beyer, S., Bode, E. HB., Bolten, CJ., Choudhuri, JV., Doss, S., Elnakady, YA., Frank, B., Gaigalat, L., Goesmann, A., Groeger, C., Gross, F., Jelsbak, L. & 37 others, Kalinowski, J., Kegler, C., Knauber, T., Konietzny, S., Kopp, M., Krause, L., Krug, D., Linke, B., Mahmud, T., Martinez-Arias, R., McHardy, AC., Merai, M., Meyer, F., Mormann, S., Muñoz-Dorado, J., Perez, J., Pradella, S., Rachid, S., Raddatz, G., Rosenau, F., Rückert, C., Sasse, F., Scharfe, M., Schuster, SC., Suen, G., Treuner-Lange, A., Velicer, GJ., Vorhölter, FJ., Weissman, KJ., Welch, RD., Wenzel, SC., Whitworth, DE., Wilhelm, S., Wittmann, C., Blöcker, H., Pühler, A. & Müller, R., 2007, In : Nature Biotechnology. 27, 11, p. 1281-1289

Research output: Contribution to journalJournal articleResearchpeer-review

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients

Jelsbak, L., Johansen, H. K., Frost, A. L. V., Thøgersen, R., Thomsen, L. E., Ciofu, O., Yang, L., Haagensen, J. A. J., Høiby, N. & Molin, S., 2007, In : Infection and Immunity. 75, 5, p. 2214-2224

Research output: Contribution to journalJournal articleResearchpeer-review

2005

Enhancer-binding proteins with a forkhead-associated domain and the sigma(54) regulon in Myxococcus xanthus fruiting body development

Jelsbak, L., Givskov, M. C. & Kaiser, D., 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 8, p. 3010-3015

Research output: Contribution to journalJournal articleResearchpeer-review

2004

σ54 enhancer binding proteins and Myxococcus xanthus fruiting body development

Jakobsen, J. S., Jelsbak, L., Jelsbak, L., Welch, R. D., Cummings, C., Goldman, B., Stark, E., Slater, S. & Kaiser, D., 2004, In : Journal of Bacteriology. 186, 13, p. 4361-4368

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1 Downloads (Pure)
2003

Cell behavior and cell-cell communication during fruiting body morphogenesis in Myxococcus xanthus

Jelsbak, L. & Søgaard-Andersen, L., 2003, In : Journal of Microbiological Methods. 55, 3, p. 829-839 11 p.

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Coupling gene expression and multicellular morphogenesis during fruiting body formation in Myxococcus xanthus

Søgaard-Andersen, L., Overgaard, M., Lobedanz, S., Ellehauge, E., Jelsbak, L. & Rasmussen, A. A., 2003, In : Molecular Microbiology. 48, 1

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