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Research Output

Poster

Immense diversity found in secondary metabolite gene clusters in filamentous fungi and bacteria using comparative genomics

Vesth, T., Frisvad, J., Kovács, Á., Jelsbak, L., Weber, T., Baker, S. E. & Andersen, M. R., 2018. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

The widespread multi-drug-resistant serotype O12 Pseudomonas aeruginosa clone emerged through concomitant horizontal transfer of serotype antigen and antibiotic resistance gene clusters

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

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293 Downloads (Pure)
Journal article

A Bacteriophage-Acquired O-Antigen Polymerase (Wzyβ) from P. aeruginosa Serotype O16 Performs a Varied Mechanism Compared to Its Cognate Wzyα

Taylor, V. L., Hoage, J. F. J., Thrane, S. W., Huszczynski, S. M., Jelsbak, L. & Lam, J. S., 2016, In : Frontiers in Microbiology. 7, 15 p., 393.

Research output: Contribution to journalJournal articleResearchpeer-review

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209 Downloads (Pure)

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.

Folkesson, A., Jelsbak, L., Yang, L., Johansen, H. K., Ciofu, O., Høiby, N. & Molin, S., 2012, In : Nature Reviews. Microbiology. 10, 12, 841 p.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations: Exploring gene profile virulence explanations

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Lillebaek, T. & Jelsbak, L., 2018, In : Scientific Reports. 8, 8 p., 11869.

Research output: Contribution to journalJournal articleResearchpeer-review

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167 Downloads (Pure)

Antibiotic combination therapy can select for broad-spectrum multidrug resistance in Pseudomonas aeruginosa

Vestergaard, M., Paulander, W., Marvig, R. L., Clasen, J., Jochumsen, N., Molin, S., Jelsbak, L., Ingmer, H. & Folkesson, S. A., 2016, In : International Journal of Antimicrobial Agents. 47, p. 48-55 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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1140 Downloads (Pure)

Application of WGS data for O-specific antigen analysis and in silico serotyping of Pseudomonas aeruginosa isolates

Thrane, S. W., Taylor, V. L., Lund, O., Lam, J. S. & Jelsbak, L., 2016, In : Journal of Clinical Microbiology. 54, 7, p. 1782-1788 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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244 Downloads (Pure)

A rare thioquinolobactin siderophore present in a bioactive Pseudomonas sp. DTU12.1

Sazinas, P., Hansen, M. L., Aune, M. I., Fischer, M. H. & Jelsbak, L., 2019, In : Genome Biology and Evolution. 11, 12, p. 3529-3533 5 p., evz267.

Research output: Contribution to journalJournal articleResearchpeer-review

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53 Downloads (Pure)

Archetypal analysis of diverse Pseudomonas aeruginosa transcriptomes reveals adaptation in cystic fibrosis airways

Thøgersen, J. C., Mørup, M., Pedersen, S. D., Molin, S. & Jelsbak, L., 2013, In : BMC Bioinformatics. 14, 1, p. 279

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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431 Downloads (Pure)

Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

Yang, L., Rau, M. H., Yang, L., Høiby, N., Molin, S. & Jelsbak, L., 2011, In : B M C Microbiology. 11, p. 184

Research output: Contribution to journalJournal articleResearchpeer-review

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242 Downloads (Pure)

Bacteriocin-mediated competition in cystic fibrosis lung infections

Ghoul, M., West, S. A., Johansen, H. K., Molin, S., Harrison, O. B., Maiden, M. C. J., Jelsbak, L., Bruce, J. B. & Griffin, A. S., 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1814, 8 p., 20150972.

Research output: Contribution to journalJournal articleResearchpeer-review

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287 Downloads (Pure)
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363 Downloads (Pure)

Cell behavior and cell-cell communication during fruiting body morphogenesis in Myxococcus xanthus

Jelsbak, L. & Søgaard-Andersen, L., 2003, In : Journal of Microbiological Methods. 55, 3, p. 829-839 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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83 Downloads (Pure)

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

Freschi, L., Jeukens, J., Kukavica-Ibrulj, I., Boyle, B., Dupont, M-J., Laroche, J., Larose, S., Maaroufi, H., Fothergill, J. L., Moore, M., Jelsbak, L. & Thrane, S. W., 2015, In : Frontiers in Microbiology. 6, 8 p., 1036.

Research output: Contribution to journalJournal articleResearchpeer-review

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215 Downloads (Pure)

Complete Genome Sequence of a Bioactive Pseudomonas sp. Strain, DTU12.3, Isolated from Soil in Denmark

Sazinas, P., Aune, M. I., Fischer, M. H., Lauritsen, J. G., Gram, L. & Jelsbak, L., 2019, In : Microbiology Resource Announcements. 8, 16, 2 p., e00121-19.

Research output: Contribution to journalJournal articleResearchpeer-review

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Complete genome sequence of the myxobacterium Sorangium cellulosum

Schneiker, S., Perlova, O., Kaiser, O., Gerth, K., Alici, A., Altmeyer, MO., Bartels, D., Bekel, T., Beyer, S., Bode, E. HB., Bolten, CJ., Choudhuri, JV., Doss, S., Elnakady, YA., Frank, B., Gaigalat, L., Goesmann, A., Groeger, C., Gross, F., Jelsbak, L. & 37 others, Kalinowski, J., Kegler, C., Knauber, T., Konietzny, S., Kopp, M., Krause, L., Krug, D., Linke, B., Mahmud, T., Martinez-Arias, R., McHardy, AC., Merai, M., Meyer, F., Mormann, S., Muñoz-Dorado, J., Perez, J., Pradella, S., Rachid, S., Raddatz, G., Rosenau, F., Rückert, C., Sasse, F., Scharfe, M., Schuster, SC., Suen, G., Treuner-Lange, A., Velicer, GJ., Vorhölter, FJ., Weissman, KJ., Welch, RD., Wenzel, SC., Whitworth, DE., Wilhelm, S., Wittmann, C., Blöcker, H., Pühler, A. & Müller, R., 2007, In : Nature Biotechnology. 27, 11, p. 1281-1289

Research output: Contribution to journalJournal articleResearchpeer-review

Coupling gene expression and multicellular morphogenesis during fruiting body formation in Myxococcus xanthus

Søgaard-Andersen, L., Overgaard, M., Lobedanz, S., Ellehauge, E., Jelsbak, L. & Rasmussen, A. A., 2003, In : Molecular Microbiology. 48, 1

Research output: Contribution to journalJournal articleResearchpeer-review

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Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment

Rau, M. H., Marvig, R. L., Ehrlich, G. D., Molin, S. & Jelsbak, L., 2012, In : Environmental Microbiology. 14, 8, p. 2200-2211

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

Marvig, R. L., Jochumsen, N., Johansen, H. K., Høiby, N., Molin, S., Sommer, M., Jelsbak, L. & Folkesson, A., 2013, In : Genome Announcements. 1, 5, 2 p., e00804-13.

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Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

Rau, M. H., Hansen, S. K., Johansen, H. K., Thomsen, L. E., Workman, C., Nielsen, K. F., Jelsbak, L., Høiby, N., Yang, L. & Molin, S., 2010, In : Environmental Microbiology. 12, 6, p. 1643-1658

Research output: Contribution to journalJournal articleResearchpeer-review

Enhancer-binding proteins with a forkhead-associated domain and the sigma(54) regulon in Myxococcus xanthus fruiting body development

Jelsbak, L., Givskov, M. C. & Kaiser, D., 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 8, p. 3010-3015

Research output: Contribution to journalJournal articleResearchpeer-review

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa.

Markussen, T., Marvig, R. L., Gómez Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., 2014, In : mBio (Online). 5, 5, p. e01592-e01514

Research output: Contribution to journalJournal articleResearchpeer-review

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

Hansen, S. K., Rau, M. H., Johansen, H. K., Ciofu, O., Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, K., von Buchwald, C., Høiby, N. & Molin, S., 2012, In : I S M E Journal. 6, 1, p. 31

Research output: Contribution to journalJournal articleResearchpeer-review

Evolutionary dynamics of bacteria in a human host environment

Yang, L., Jelsbak, L., Marvig, R. L., Pedersen, S. D., Workman, C., Rau, M. H., Hansen, S. K., Folkesson, A., Johansen, H. K., Ciofu, O., Høiby, N., Sommer, M. & Molin, S., 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 18, p. 7481-7486

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

Marvig, R. L., Madsen Sommer, L. M., Jelsbak, L., Molin, S. & Johansen, H. K., 2015, In : Future Microbiology. 10, 4, p. 599-611 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

Pedersen, S. D., Yang, L., Molin, S. & Jelsbak, L., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 19, p. 7766-7771

Research output: Contribution to journalJournal articleResearchpeer-review

Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

Frydenlund Michelsen, C., Khademi, S. M. H., Johansen, H. K., Ingmer, H., Dorrestein, P. C. & Jelsbak, L., 2016, In : I S M E Journal. 10, p. 1323-1336 14 p.

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Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators.

Marvig, R. L., Johansen, H. K., Molin, S. & Jelsbak, L., 2013, In : P L o S Genetics. 9, 9, e1003741.

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Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate

Norman, A., Ciofu, O., Amador Hierro, C. I., Høiby, N. & Jelsbak, L., 2016, In : Genome Announcements. 4, 1, 2 p., e00008-16.

Research output: Contribution to journalJournal articleResearchpeer-review

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205 Downloads (Pure)

Genomic epidemiology of a major Mycobacterium tuberculosis outbreak: Retrospective cohort study in a low incidence setting using sparse time-series sampling

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Jelsbak, L. & Lillebaek, T., 2017, In : Journal of Infectious Diseases. 216, 3, 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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195 Downloads (Pure)

HldE Is Important for Virulence Phenotypes in Enterotoxigenic Escherichia coli

Maigaard Hermansen, G. M., Boysen, A., Krogh, T. J., Nawrocki, A., Jelsbak, L. & Møller-Jensen, J., 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 253, 13 p., 253.

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In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

Yang, L., Haagensen, J. A. J., Jelsbak, L., Johansen, H. K., Sternberg, C., Høiby, N. & Molin, S., 2008, In : Journal of Bacteriology. 190, 8, p. 2767-2776

Research output: Contribution to journalJournal articleResearchpeer-review

Intergenic evolution during host adaptation increases expression of the metallophore pseudopaline in Pseudomonas aeruginosa

Hermansen, G. M. M., Hansen, M. L., Khademi, S. M. H. & Jelsbak, L., 2018, In : Microbiology. 164, 8, p. 1038-1047

Research output: Contribution to journalJournal articleResearchpeer-review

Microbial ecology and adaptation in cystic fibrosis airways

Yang, L., Jelsbak, L. & Molin, S., 2011, In : Environmental Microbiology. 13, 7, p. 1682-1689

Research output: Contribution to journalJournal articleResearchpeer-review

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients

Jelsbak, L., Johansen, H. K., Frost, A. L. V., Thøgersen, R., Thomsen, L. E., Ciofu, O., Yang, L., Haagensen, J. A. J., Høiby, N. & Molin, S., 2007, In : Infection and Immunity. 75, 5, p. 2214-2224

Research output: Contribution to journalJournal articleResearchpeer-review

Multilocus Sequence Typing of Total-Genome-Sequenced Bacteria

Larsen, M. V., Cosentino, S., Rasmussen, S., Rundsten, C. F., Hasman, H., Marvig, R. L., Jelsbak, L., Sicheritz-Pontén, T., Ussery, D. W., Aarestrup, F. M. & Lund, O., 2012, In : Journal of Clinical Microbiology. 50, 4, p. 1355-1361

Research output: Contribution to journalJournal articleResearchpeer-review

3 Downloads (Pure)

Mutations in 23S rRNA Confer Resistance against Azithromycin in Pseudomonas aeruginosa

Marvig, R. L., Søndergaard, M. S. R., Pedersen, S. D., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., 2012, In : Antimicrobial Agents and Chemotherapy. 56, 8, p. 4519-4521

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Pattern formation: fruiting body morphogenesis in Myxococcus xanthus

Jelsbak, L. & Sogaard-Andersen, L., 2000, In : Current Opinion in Microbiology. 3, 6, p. 637-642 6 p.

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Pattern formation by a cell surface-associated morphogen in Myxococcus xanthus

Jelsbak, L. & Sogaard-Andersen, L., 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 4, p. 2032-2037 6 p.

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35 Downloads (Pure)

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

Bartell, J., Blazier, A. S., Yen, P., Thøgersen, J. C., Jelsbak, L., Goldberg, J. B. & Papin, J. A., 2017, In : Nature Communications. 8, 13 p., 14631.

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Recurrent tuberculosis in patients infected with the predominant Mycobacterium tuberculosis outbreak strain in Denmark. New insights gained through whole genome sequencing

Folkvardsen, D. B., Norman, A., Rasmussen, E. M., Lillebaek, T., Jelsbak, L. & Andersen, Å. B., 2020, In : Infection, Genetics and Evolution. 80, 6 p., 104169.

Research output: Contribution to journalJournal articleResearchpeer-review

SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

Lauridsen, R. K., Madsen Sommer, L. M., Johansen, H. K., Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, S. B. & Boisen, A., 2017, In : Scientific Reports. 7, 7 p., 45264.

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Wang, M., Carver, J. J., Pevzner, P., Mohiman, H., Bandeira, N., Phelan, V. V., Sanchez, L. M., Garg, N., Watrous, J., Luzzatto-Knaa, T., Frydenlund Michelsen, C., Jelsbak, L., Månsson, M., Klitgaard, A. & Nielsen, K. F., 2016, In : Nature Biotechnology. 34, 8, p. 828-837 10 p.

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Staphylococcus aureus Alters Growth Activity, Autolysis, and Antibiotic Tolerance in a Human Host-Adapted Pseudomonas aeruginosa Lineage.

Frydenlund Michelsen, C., Christensen, A-M., Bojer, M. S., Høiby, N., Ingmer, H. & Jelsbak, L., 2014, In : Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Substantial molecular evolution and mutation rates in prolonged latent Mycobacterium tuberculosis infection in humans

Lillebaek, T., Norman, A., Rasmussen, E. M., Marvig, R. L., Bek Folkvardsen, D., Bengaard Andersen, Å. & Jelsbak, L., 2016, In : International Journal of Medical Microbiology. 306, 7, p. 580-585 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions

Jochumsen, N., Marvig, R. L., Pedersen, S. D., Jensen, R. L., Paulander, W., Molin, S., Jelsbak, L. & Folkesson, A., 2016, In : Nature Communications. 7, 10 p., 13002.

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The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

Wassermann, T., Meinike Jørgensen, K., Ivanyshyn, K., Bjarnsholt, T., Khademi, S. M. H., Jelsbak, L., Høiby, N. & Ciofu, O., 2016, In : Microbiology. 162, 5, p. 865-875 11 p.

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The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015, In : mBio (Online). 6, 5, 10 p., e01396-15.

Research output: Contribution to journalJournal articleResearchpeer-review

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Transcriptomic profiling of interacting nasal staphylococci species reveals global changes in gene and non-coding RNA expression

Hermansen, G. M. M., Sazinas, P., Kofod, D., Millard, A., Andersen, P. S. & Jelsbak, L., 2018, In : FEMS Microbiology Letters. 365, 5, 9 p., fny004.

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