19992022
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Research Output 1999 2019

2019
107 Downloads (Pure)

Complete Genome Sequence of a Bioactive Pseudomonas sp. Strain, DTU12.3, Isolated from Soil in Denmark

Sazinas, P., Aune, M. I., Fischer, M. H., Lauritsen, J. G., Gram, L. & Jelsbak, L., 2019, In : Microbiology Resource Announcements. 8, 16, 2 p., e00121-19.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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66 Downloads (Pure)

Within-host adaptation mediated by intergenic evolution in Pseudomonas aeruginosa

Khademi, S. M. H., Sazinas, P. & Jelsbak, L., 2019, In : Genome Biology and Evolution. 11, 5, p. 1385-1397 13 p., evz083.

Research output: Contribution to journalJournal articleResearchpeer-review

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2018
112 Downloads (Pure)

A Major Mycobacterium tuberculosis outbreak caused by one specific genotype in a low-incidence country: Exploring gene profile virulence explanations: Exploring gene profile virulence explanations

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Lillebaek, T. & Jelsbak, L., 2018, In : Scientific Reports. 8, 8 p., 11869.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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133 Downloads (Pure)

Developing a CRISPR/CAS9-assisted recombineering system for natural soil pseudomonads

Hansen, M. L. & Jelsbak, L., 2018, The Danish Microbiological Society Annual Congress 2018 - programme & abstracts. Copenhagen, Denmark: Danish Microbiological Society, p. 34-35

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
110 Downloads (Pure)

HldE Is Important for Virulence Phenotypes in Enterotoxigenic Escherichia coli

Maigaard Hermansen, G. M., Boysen, A., Krogh, T. J., Nawrocki, A., Jelsbak, L. & Møller-Jensen, J., 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 253, 13 p., 253.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Immense diversity found in secondary metabolite gene clusters in filamentous fungi and bacteria using comparative genomics

Vesth, T., Frisvad, J., Kovács, Á., Jelsbak, L., Weber, T., Baker, S. E. & Andersen, M. R., 2018. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Intergenic evolution during host adaptation increases expression of the metallophore pseudopaline in Pseudomonas aeruginosa

Hermansen, G. M. M., Hansen, M. L., Khademi, S. M. H. & Jelsbak, L., 2018, In : Microbiology. 164, 8, p. 1038-1047

Research output: Contribution to journalJournal articleResearchpeer-review

74 Downloads (Pure)

The identification and study of adaptive intergenic mutations in bacterial pathogens

Sazinas, P., Anbo, M. & Jelsbak, L., 2018, The Danish Microbiological Society Annual Congress 2018 - programme & abstracts. Copenhagen, Denmark: Danish Microbiological Society, p. 67-67

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
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95 Downloads (Pure)

Transcriptomic profiling of interacting nasal staphylococci species reveals global changes in gene and non-coding RNA expression

Hermansen, G. M. M., Sazinas, P., Kofod, D., Millard, A., Andersen, P. S. & Jelsbak, L., 2018, In : FEMS Microbiology Letters. 365, 5, 9 p., fny004.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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2017

Application of RNA-seq and Bioimaging Methods to Study Microbe-Microbe Interactions and Their Effects on Biofilm Formation and Gene Expression

Amador Hierro, C. I., Sternberg, C. & Jelsbak, L., 2017, Host-Pathogen Interactions. López-Baena, F. J. & Medina, C. (eds.). Springer, Vol. 1734. p. 131-158 28 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

129 Downloads (Pure)

Genomic epidemiology of a major Mycobacterium tuberculosis outbreak: Retrospective cohort study in a low incidence setting using sparse time-series sampling

Folkvardsen, D. B., Norman, A., Andersen, Å. B., Rasmussen, E. M., Jelsbak, L. & Lillebaek, T., 2017, In : Journal of Infectious Diseases. 216, 3, 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
234 Downloads (Pure)

Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis

Bartell, J., Blazier, A. S., Yen, P., Thøgersen, J. C., Jelsbak, L., Goldberg, J. B. & Papin, J. A., 2017, In : Nature Communications. 8, 13 p., 14631.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
223 Downloads (Pure)

SERS detection of the biomarker hydrogen cyanide from Pseudomonas aeruginosa cultures isolated from cystic fibrosis patients

Lauridsen, R. K., Madsen Sommer, L. M., Johansen, H. K., Rindzevicius, T., Molin, S., Jelsbak, L., Engelsen, S. B. & Boisen, A., 2017, In : Scientific Reports. 7, 7 p., 45264.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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2016
152 Downloads (Pure)

A Bacteriophage-Acquired O-Antigen Polymerase (Wzyβ) from P. aeruginosa Serotype O16 Performs a Varied Mechanism Compared to Its Cognate Wzyα

Taylor, V. L., Hoage, J. F. J., Thrane, S. W., Huszczynski, S. M., Jelsbak, L. & Lam, J. S., 2016, In : Frontiers in Microbiology. 7, 15 p., 393.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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918 Downloads (Pure)

Antibiotic combination therapy can select for broad-spectrum multidrug resistance in Pseudomonas aeruginosa

Vestergaard, M., Paulander, W., Marvig, R. L., Clasen, J., Jochumsen, N., Molin, S., Jelsbak, L., Ingmer, H. & Folkesson, S. A., 2016, In : International Journal of Antimicrobial Agents. 47, p. 48-55 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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203 Downloads (Pure)

Application of WGS data for O-specific antigen analysis and in silico serotyping of Pseudomonas aeruginosa isolates

Thrane, S. W., Taylor, V. L., Lund, O., Lam, J. S. & Jelsbak, L., 2016, In : Journal of Clinical Microbiology. 54, 7, p. 1782-1788 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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294 Downloads (Pure)
Open Access
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Curbing the development and spread of 'high risk' bacterial pathogens

Jelsbak, L., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
188 Downloads (Pure)

Evolution of metabolic divergence in Pseudomonas aeruginosa during long-term infection facilitates a proto-cooperative interspecies interaction

Frydenlund Michelsen, C., Khademi, S. M. H., Johansen, H. K., Ingmer, H., Dorrestein, P. C. & Jelsbak, L., 2016, In : I S M E Journal. 10, p. 1323-1336 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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164 Downloads (Pure)

Genome Sequence of Pseudomonas aeruginosa Strain DK1-NH57388A, a Stable Mucoid Cystic Fibrosis Isolate

Norman, A., Ciofu, O., Amador Hierro, C. I., Høiby, N. & Jelsbak, L., 2016, In : Genome Announcements. 4, 1, 2 p., e00008-16.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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90 Downloads (Pure)

Modulation of S. aureus Quorum Sensing by P. aeruginosa

Amador Hierro, C. I. & Jelsbak, L., 2016, Programme & Abstracts. The Danish Microbiological Society Annual Congress 2016. Danish Microbiological Society, p. 44 1 p. P19

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

Open Access
File
307 Downloads (Pure)

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Wang, M., Carver, J. J., Pevzner, P., Mohiman, H., Bandeira, N., Phelan, V. V., Sanchez, L. M., Garg, N., Watrous, J., Luzzatto-Knaa, T., Frydenlund Michelsen, C., Jelsbak, L., Månsson, M., Klitgaard, A. & Nielsen, K. F., 2016, In : Nature Biotechnology. 34, 8, p. 828-837 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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216 Downloads (Pure)

Substantial molecular evolution and mutation rates in prolonged latent Mycobacterium tuberculosis infection in humans

Lillebaek, T., Norman, A., Rasmussen, E. M., Marvig, R. L., Bek Folkvardsen, D., Bengaard Andersen, Å. & Jelsbak, L., 2016, In : International Journal of Medical Microbiology. 306, 7, p. 580-585 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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168 Downloads (Pure)

The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is shaped by strong epistatic interactions

Jochumsen, N., Marvig, R. L., Pedersen, S. D., Jensen, R. L., Paulander, W., Molin, S., Jelsbak, L. & Folkesson, A., 2016, In : Nature Communications. 7, 10 p., 13002.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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352 Downloads (Pure)

The phenotypic evolution of Pseudomonas aeruginosa populations changes in the presence of subinhibitory concentrations of ciprofloxacin

Wassermann, T., Meinike Jørgensen, K., Ivanyshyn, K., Bjarnsholt, T., Khademi, S. M. H., Jelsbak, L., Høiby, N. & Ciofu, O., 2016, In : Microbiology. 162, 5, p. 865-875 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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210 Downloads (Pure)

Utilization and control of ecological interactions in polymicrobial infections and community-based microbial cell factories

Wigneswaran, V., Amador Hierro, C. I., Jelsbak, L., Sternberg, C. & Jelsbak, L., 2016, In : F1000Research. 5, 7 p., 421.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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2015
237 Downloads (Pure)

Bacteriocin-mediated competition in cystic fibrosis lung infections

Ghoul, M., West, S. A., Johansen, H. K., Molin, S., Harrison, O. B., Maiden, M. C. J., Jelsbak, L., Bruce, J. B. & Griffin, A. S., 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1814, 8 p., 20150972.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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162 Downloads (Pure)

Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

Freschi, L., Jeukens, J., Kukavica-Ibrulj, I., Boyle, B., Dupont, M-J., Laroche, J., Larose, S., Maaroufi, H., Fothergill, J. L., Moore, M., Jelsbak, L. & Thrane, S. W., 2015, In : Frontiers in Microbiology. 6, 8 p., 1036.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Epistatic Mutations And Unpredictable Phenotypes In Pseudomonas Aeruginosa

Andresen, E. K., Abou Hachem, M. & Jelsbak, L., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 49-49

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Evolutionary insight from whole-genome sequencing of Pseudomonas aeruginosa from cystic fibrosis patients

Marvig, R. L., Madsen Sommer, L. M., Jelsbak, L., Molin, S. & Johansen, H. K., 2015, In : Future Microbiology. 10, 4, p. 599-611 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Genomic Evolution Of The Mdr Serotype O12 Pseudomonas Aeruginosa Clone

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 48-48

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Novel Path Towards Colistin Resistance In Pseudomonas Aeruginosa During Chronic Infection Involves Polymorphisms In Uncharacterized Glycosyltransferase Gene

Hermansen, G. M. M. & Jelsbak, L., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 32-33

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

86 Downloads (Pure)

phuR intergenic mutation results in pleiotropic effects on global gene expression

Khademi, S. M. H., Wassermann, T., Ciofu, O. & Jelsbak, L., 2015, Proceedings of the ASM Conference on Pseudomonas 2015. American Society for Microbiology, p. 126-127 126

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
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Rnaseq As A Method To Study Microbial Interactions Arising In The Cystic Fibrosis Airways

Amador Hierro, C. I. & Jelsbak, L., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 68-68

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Substantial Molecular Evolution In Prolonged Latent Mycobacterium Tuberculosis Infections In Humans

Lillebaek, T., Norman, A., Rasmussen, E. M., B. Folkvardsen, D., Marvig, R., Bengaard Andersen, Å. & Jelsbak, L., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 50-50

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

142 Downloads (Pure)

The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015, In : mBio (Online). 6, 5, 10 p., e01396-15.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
263 Downloads (Pure)

The widespread multi-drug-resistant serotype O12 Pseudomonas aeruginosa clone emerged through concomitant horizontal transfer of serotype antigen and antibiotic resistance gene clusters

Thrane, S. W., Taylor, V. L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J-P., Lévesque, R. C., Lam, J. S. & Jelsbak, L., 2015. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
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72 Downloads (Pure)

Working in the biomedical engineering domain: opportunities and challenges

Jelsbak, L., 2015, Book of Abstracts. DTU's Sustain Conference 2015. Lyngby: Technical University of Denmark, 1 p. Q-1

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
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2014

Environmental heterogeneity drives within-host diversification and evolution of Pseudomonas aeruginosa.

Markussen, T., Marvig, R. L., Gómez Lozano, M., Aanæs, K., Burleigh, A. E., Høiby, N., Johansen, H. K., Molin, S. & Jelsbak, L., 2014, In : mBio (Online). 5, 5, p. e01592-e01514

Research output: Contribution to journalJournal articleResearchpeer-review

Staphylococcus aureus Alters Growth Activity, Autolysis, and Antibiotic Tolerance in a Human Host-Adapted Pseudomonas aeruginosa Lineage.

Frydenlund Michelsen, C., Christensen, A-M., Bojer, M. S., Høiby, N., Ingmer, H. & Jelsbak, L., 2014, In : Journal of Bacteriology. 196, 22, p. 3903-3911 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Within-host evolution of Pseudomonas aeruginosa reveals adaptation toward iron acquisition from hemoglobin.

Marvig, R. L., Pedersen, S. D., Khademi, S. M. H., Markussen, T., Molin, S. & Jelsbak, L., 2014, In : mBio (Online). 5, 3, e00966-14.

Research output: Contribution to journalJournal articleResearchpeer-review

83 Downloads (Pure)

Within-host evolution of Pseudomonas aeruginosa toward iron acquisition from hemoglobin in polymicrobial CF infections

Khademi, S. M. H., Marvig, R. L., Pedersen, S. D. & Jelsbak, L., 2014, Proceedings of the 5th ASM Conference on Cell-Cell Communication in Bacteria. American Society for Microbiology, p. 60-61 46

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
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2013
375 Downloads (Pure)

Archetypal analysis of diverse Pseudomonas aeruginosa transcriptomes reveals adaptation in cystic fibrosis airways

Thøgersen, J. C., Mørup, M., Pedersen, S. D., Molin, S. & Jelsbak, L., 2013, In : BMC Bioinformatics. 14, 1, p. 279

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
202 Downloads (Pure)

Draft Genome Sequences of Pseudomonas aeruginosa B3 Strains Isolated from a Cystic Fibrosis Patient Undergoing Antibiotic Chemotherapy

Marvig, R. L., Jochumsen, N., Johansen, H. K., Høiby, N., Molin, S., Sommer, M., Jelsbak, L. & Folkesson, A., 2013, In : Genome Announcements. 1, 5, 2 p., e00804-13.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts

Pedersen, S. D., Yang, L., Molin, S. & Jelsbak, L., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 19, p. 7766-7771

Research output: Contribution to journalJournal articleResearchpeer-review

262 Downloads (Pure)

Genome Analysis of a Transmissible Lineage of Pseudomonas aeruginosa Reveals Pathoadaptive Mutations and Distinct Evolutionary Paths of Hypermutators.

Marvig, R. L., Johansen, H. K., Molin, S. & Jelsbak, L., 2013, In : P L o S Genetics. 9, 9, e1003741.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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292 Downloads (Pure)

Typing of Pseudomonas aeruginosa from hemorrhagic pneumonia in mink (Neovison vison)

Salomonsen, C. M., Themudo, G. E., Jelsbak, L., Molin, S., Høiby, N. & Hammer, A. S., 2013, In : Veterinary Microbiology. 163, 1-2, p. 103-109

Research output: Contribution to journalJournal articleResearchpeer-review

File
2012
1 Downloads (Pure)

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective.

Folkesson, A., Jelsbak, L., Yang, L., Johansen, H. K., Ciofu, O., Høiby, N. & Molin, S., 2012, In : Nature Reviews. Microbiology. 10, 12, 841 p.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Deletion and acquisition of genomic content during early stage adaptation of Pseudomonas aeruginosa to a human host environment

Rau, M. H., Marvig, R. L., Ehrlich, G. D., Molin, S. & Jelsbak, L., 2012, In : Environmental Microbiology. 14, 8, p. 2200-2211

Research output: Contribution to journalJournal articleResearchpeer-review

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

Hansen, S. K., Rau, M. H., Johansen, H. K., Ciofu, O., Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, K., von Buchwald, C., Høiby, N. & Molin, S., 2012, In : I S M E Journal. 6, 1, p. 31

Research output: Contribution to journalJournal articleResearchpeer-review