Publications per year
Publications per year
Personal profile
Profile
Tilmann Weber is Professor for Natural Products Genome Mining and Associate Scientific Director of the Natural Products Genome Mining group at the Novo Nordisk Foundation Center for Biosustainability of the Technical University of Denmark. His main research interest is focused on deciphering the molecular pathways and engineering the biosynthesis of natural products by combining genetic, biochemical and bioinformatics methods. He is a pioneer in developing software for the automated genome mining (CLUSEAN, antiSMASH, antiSMASH-DB) and analysis of secondary metabolite biosynthetic pathways. His group was able to firstly elucidate the biosynthetic pathways of the elfamycin family of antibiotics and is deeply involved in developing CRISPR-based metabolic engineering tools for actinomycetes.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Revolutionizing biotechnology advances natural products discovery and industrial processing
Tong, Y. & Weber, T., 2025, In: Synthetic and Systems Biotechnology. 10, 1, p. 156-157 2 p.Research output: Contribution to journal › Editorial
Open AccessFile16 Downloads (Pure) -
Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Yang, Z., Qiao, Y., Strøbech, E., Morth, J. P., Walther, G., Jørgensen, T. S., Lum, K. Y., Peschel, G., Rosenbaum, M. A., Previtali, V., Clausen, M. H., Lukassen, M. V., Gotfredsen, C. H., Kurzai, O., Weber, T. & Ding, L., 2024, In: Nature Communications. 15, 12 p., 9259.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile21 Downloads (Pure) -
A treasure trove of 1034 actinomycete genomes
Jorgensen, T. S., Mohite, O. S., Sterndorff, E. B., Alvarez-Arevalo, M., Blin, K., Booth, T. J., Charusanti, P., Faurdal, D., Hansen, T. O., Nuhamunada, M., Mourched, A.-S., Palsson, B. O. & Weber, T., 2024, In: Nucleic Acids Research. 52, 13, p. 7487–7503 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile25 Downloads (Pure) -
BGC Atlas: a web resource for exploring the global chemical diversity encoded in bacterial genomes
Bağcı, C., Nuhamunada, M., Goyat, H., Ladanyi, C., Sehnal, L., Blin, K., Kautsar, S. A., Tagirdzhanov, A., Gurevich, A., Mantri, S., von Mering, C., Udwary, D., Medema, M. H., Weber, T. & Ziemert, N., 2024, (Accepted/In press) In: Nucleic Acids Research.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Downloads (Pure) -
BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets
Nuhamunada, M., Mohite, O. S., Phaneuf, P. V., Palsson, B. O. & Weber, T., 2024, In: Nucleic Acids Research. 52, 10, p. 5478-5495Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Downloads (Pure)
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Leveraging knowledge graphs to identify microbial communities in diverse biological contexts
Phanthanourak, A. L. (PhD Student), Santos Delgado, A. (Main Supervisor), Weber, T. (Supervisor) & Krogh, A. (Supervisor)
01/05/2024 → 30/04/2027
Project: PhD
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Metagenomic Approaches to Assess the Secondary Metabolome of Soil Bacteria
Faurdal, D. L. (PhD Student), Weber, T. (Main Supervisor) & Strube, M. L. (Supervisor)
01/03/2024 → 28/02/2027
Project: PhD
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Streptomyces systems biology and fermentation
Brockmann, S. (PhD Student), Weber, T. (Main Supervisor) & Yang, L. (Supervisor)
01/03/2024 → 28/02/2027
Project: PhD
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Large-scale Genome Mining for Streptomyces BGCs (DC6)
Damas Ramos, L. C. (PhD Student), Weber, T. (Main Supervisor) & Cruz-Morales, P. (Supervisor)
01/10/2023 → 30/09/2026
Project: PhD
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Fungal metabolomics-driven discovery of natural products
Romero, A. (PhD Student), Weber, T. (Main Supervisor) & Larsen, T. O. (Supervisor)
01/09/2023 → 31/08/2026
Project: PhD
Activities
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Integrating informatics, metabolic engineering and synthetic biology for the discovery of novel bioactive molecules
Weber, T. (Keynote speaker)
26 Sept 2024Activity: Talks and presentations › Conference presentations
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The Molecular Treasure Hunt: From Genes to Molecules
Weber, T. (Keynote speaker)
22 Sept 2024Activity: Talks and presentations › Conference presentations
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MAtching Genes with MOLecules for FUNctional analaysis (MAGic-MOLFUN)
Weber, T. (Invited speaker)
30 May 2024Activity: Talks and presentations › Talks and presentations in private or public companies and organisations
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Integrating Informatics and Metabolic Engineering for the discovery of Novel Antibiotics
Weber, T. (Invited speaker)
23 Apr 2024Activity: Talks and presentations › Conference presentations
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Natural Products Genome Mining and Biosynthesis symposium 2024
Weber, T. (Organizer)
23 Apr 2024Activity: Attending an event › Participating in or organising a conference
Prizes
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Clarivate Highly Cited Researcher 2020
Weber, T. (Recipient), 2020
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2021
Weber, T. (Recipient), 16 Nov 2021
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2022
Weber, T. (Recipient), 15 Nov 2022
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2023
Weber, T. (Recipient), 15 Nov 2023
Prize: Prizes, scholarships, distinctions
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Clarivate Highly Cited Researcher 2024
Weber, T. (Recipient), 19 Nov 2024
Prize: Prizes, scholarships, distinctions
Press/Media
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Closing ceremony of "Small World Initiative" course at University of Santiago de Compostela, Spain
04/05/2018
1 Media contribution
Press/Media: Press / Media
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Millions for research into antibiotic resistance and better drugs
Weber, T., Charusanti, P., Lee, S. Y. & Palsson, B.
26/01/2017 → 26/12/2017
2 items of Media coverage, 2 Media contributions
Press/Media: Press / Media
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Video and Blog-post / interview at sciencenews.dk on iimena project (NNF Challenge Grant)
24/11/2017
1 item of Media coverage
Press/Media: Press / Media
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Scientists solve 30-year old mystery on how resistance genes spread
Weber, T., Sommer, M. O. A., Jiang, X., Lee, S. Y., Ellabaan, M. M. H., Charusanti, P., Munck, C., Blin, K. & Tong, Y.
15/06/2017
1 Media contribution
Press/Media: Press / Media
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Scientists discover how to make ‘click-on’ antibiotics
Weber, T., Lee, S. Y. & Musiol-Kroll, E. M.
04/04/2017
1 Media contribution
Press/Media: Press / Media