• Søltofts Plads, 229, 160

    2800 Kgs.Lyngby

    Denmark

1977 …2020

Research output per year

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Research Output

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Journal article
2020

Modeling and system identification of an unconventional bioreactor used for single cell protein production

Petersen, L. A. H., Bequette, B. W., Jørgensen, S. B., Villadsen, J., Christensen, I. & Gernaey, K. V., 2020, In : Chemical Engineering Journal. 390, 13 p., 124438.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Dynamic investigation and modeling of the nitrogen co-metabolism in Methylococcus capsulatus (Bath)

Petersen, L. A. H., Lieven, C., Nandy, S. K., Villadsen, J., Jørgensen, S. B., Christensen, I. & Gernaey, K. V., 2019, In : Biotechnology and Bioengineering. 116, 11, p. 2884-2895

Research output: Contribution to journalJournal articleResearchpeer-review

2017

Mixing and mass transfer in a pilot scale U-loop bioreactor

Petersen, L. A. H., Villadsen, J., Jørgensen, S. B. & Gernaey, K., 2017, In : Biotechnology and Bioengineering. 114, 2, 31 p., 344–354.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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913 Downloads (Pure)
2016

System wide cofactor turnovers can propagate metabolic stability between pathways

Yang, Y., Guan, Y. H. & Villadsen, J., 2016, In : Metabolic Engineering Communications. 3, p. 196-204 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
170 Downloads (Pure)
2015

Oxidative phosphorylation revisited

Nath, S. & Villadsen, J., 2015, In : Biotechnology and Bioengineering. 112, 3, p. 429-437

Research output: Contribution to journalJournal articleResearchpeer-review

2014

Reflections on the aerobic fermentation stoichiometry of crabtree positive yeasts

Villadsen, J. & Jørgensen, S. B., 2014, In : Biotechnology and Bioengineering (Print). 111, 3, p. 632-637

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Use of continuous lactose fermentation for ethanol production by Kluveromyces marxianus for verification and extension of a biochemically structured model

Sansonetti, S., Hobley, T. J., Curcio, S., Villadsen, J. & Sin, G., 2013, In : Bioresource Technology. 130, p. 703-709

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Use of high-gradient magnetic fishing for reducing proteolysis during fermentation.

Maury, T. L., Ottow, K. E., Brask, J., Villadsen, J. & Hobley, T. J., 2012, In : Biotechnology Journal. 7, 7, p. 909-918

Research output: Contribution to journalJournal articleResearchpeer-review

2011

A biochemically structured model for ethanol fermentation by Kluyveromyces marxianus: A batch fermentation and kinetic study

Sansonetti, S., Hobley, T. J., Calabrò, V., Villadsen, J. & Sin, G., 2011, In : Bioresource Technology. 102, 16, p. 7513-7520

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)
2009

Introduction

Villadsen, J., 2009, In : Biotechnology and Bioengineering (Print). 104, p. 617-617

Research output: Contribution to journalJournal articleResearchpeer-review

The sugar industry - the cradle of modern bio-industry

Villadsen, J., 2009, In : Biotechnology Journal. 4, 5, p. 620-631

Research output: Contribution to journalJournal articleResearchpeer-review

2007

Innovative technology to meet the demands of the white biotechnology revolution of chemical production

Villadsen, J., 2007, In : Chemical Engineering Science. 62, 24, p. 6957-6968

Research output: Contribution to journalJournal articleResearchpeer-review

Optimal fed-batch cultivation when mass transfer becomes limiting

Villadsen, J. & Patil, K. R., 2007, In : Biotechnology and Bioengineering. 98, 3, p. 706-710

Research output: Contribution to journalJournal articleResearchpeer-review

Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: Kinetics and operational stability

Nordkvist, M., Nielsen, P. M. & Villadsen, J., 2007, In : Biotechnology and Bioengineering. 97, 4, p. 694 - 707

Research output: Contribution to journalJournal articleResearchpeer-review

Scale-up of enzymatic production of lactobionic acid using the rotary jet head system

Hua, L., Nordkvist, M., Nielsen, P. M. & Villadsen, J., 2007, In : Biotechnology and Bioengineering (Print). 97, 4, p. 842-849

Research output: Contribution to journalJournal articleResearchpeer-review

2006

Section B - The Teaching of Bio-reaction Engineering to Students and Professionals

Villadsen, J., 2006, In : Indian Chemical Engineer. 48, 1, p. 54-61

Research output: Contribution to journalJournal articleResearchpeer-review

2005

Batch reactors in the Bioindustries

Villadsen, J., 2005, In : Batch Processes. p. 83-106

Research output: Contribution to journalJournal articleResearchpeer-review

2003

Applying rotary jet heads for mixing and mass transfer in a forced recirculation tank reactor system

Nordkvist, M., Grotkjær, T., Hummer, J. S. & Villadsen, J., 2003, In : Chemical Engineering Science. 58, 17, p. 3877-3890

Research output: Contribution to journalJournal articleResearchpeer-review

Glucose metabolism in Lactococcus lactis MG1363 under different aeration conditions: Requirement of acetate to sustain growth under microaerobic conditions

Nordkvist, M., Jensen, N. B. S. & Villadsen, J., 2003, In : Applied and Environmental Microbiology. 69, 6, p. 3462-3468

Research output: Contribution to journalJournal articleResearchpeer-review

2002

Production of teicoplanin by Actinoplanes teichomyceticus in continuous fermentation

Vara, A. G., Hochkoepple, A., Nielsen, J. & Villadsen, J., 2002, In : Biotechnology and Bioengineering. 77, 5, p. 589-598

Research output: Contribution to journalJournal articleResearchpeer-review

The level of pyruvate-formate lyase controls the shift from homolactic to mixed-acid product formation in Lactococcus lactis

Melchiorsen, C. R., Jokumsen, K. V., Villadsen, J., Israelsen, H. & Arnau, J., 2002, In : Applied Microbiology and Biotechnology. 58, 3, p. 338-344

Research output: Contribution to journalJournal articleResearchpeer-review

The simultaneous biosynthesis and uptake of amino acids by Lactococcus lactis studied by C-13-labeling experiments

Jensen, N. B. S., Christensen, B., Nielsen, J. & Villadsen, J., 2002, In : Biotechnology and Bioengineering. 78, 1, p. 11-16

Research output: Contribution to journalJournal articleResearchpeer-review

2001

Bioreactors: a chemical engineering perspective

Leib, T. M., Pereira, C. J. & Villadsen, J., 2001, In : Chemical Engineering Science. 56, 19, p. 5485-5497

Research output: Contribution to journalJournal articleResearchpeer-review

Dynamics of pyruvate metabolism in Lactococcus lactis

Melchiorsen, C. R., Jensen, N. B. S., Christensen, B., Jochumsen, K. V. & Villadsen, J., 2001, In : Biotechnology and Bioengineering. 74, 4, p. 271-279

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool

Nissen, T. L., Anderlund, M., Nielsen, J., Villadsen, J. & Kielland-Brandt, M. C., 2001, In : Yeast. 18, 1, p. 19-32

Research output: Contribution to journalJournal articleResearchpeer-review

Metabolic behavior of Lactococcus lactis MG1363 in microaerobic continuous cultivation at a low dilution rate

Jensen, N. B. S., Melchiorsen, C. R., Jochumsen, K. V. & Villadsen, J., 2001, In : Applied and Environmental Microbiology. 67, 6, p. 2677-2682

Research output: Contribution to journalJournal articleResearchpeer-review

2000

Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis

Nissen, T. L., Hamann, C. W., Kielland-Brandt, M. C., Nielsen, J. & Villadsen, J., 2000, In : Yeast. 16, 5, p. 463-474

Research output: Contribution to journalJournal articleResearchpeer-review

Optimization of Ethanol Production in Saccharomyces cerevisiae by Metabolic Engineering of the Ammonium Assimilation

Nissen, T. L., Kielland-Brandt, M. C., Nielsen, J. & Villadsen, J., 2000, In : Metabolic Engineering. 2, 1, p. 69-77

Research output: Contribution to journalJournal articleResearchpeer-review

Synthesis and posttranslational regulation of pyruvate formate-lyase in Lactococcus lactis

Melchiorsen, C. R., Jochumsen, K. V., Villadsen, J., Johnsen, M. G., Israelsen, H. & Arnau, J., 2000, In : Journal of Bacteriology. 182, 17, p. 4738-4788

Research output: Contribution to journalJournal articleResearchpeer-review

1999

Determination of the phosphorylated sugars of the Embden-Meyerhoff-Parnas Pathway in Lactococcus lactis using a fast sampling technique and solid phase extraction

Jensen, N. B. S., Jokumsen, K. V. & Villadsen, J., 1999, In : Biotechnology and Bioengineering. 63, 3, p. 356-362

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of the E.coli pntA and pntB genes encoding nicotinamide nucleotide transhydrogenase in Saccharomyces cerevisiae and its effect on product formation during anaerobic glucose fermentation

Anderlund, M., Nissen, T. L., Nielsen, J. B., Villadsen, J., Rydström, J., Hahn-Hägerdal, B. & Kielland-Brandt, M. C., 1999, In : APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 65, 6, p. 2333-2340

Research output: Contribution to journalJournal articleResearchpeer-review

Glucose/citrate cometabolisme in Lactococcus lactis subsp. lactis biovar diacetylactis with impaired alpha-acetolactate decarboxylase

Curic, M., de Richelieu, M., Henriksen, C. M., Jokumsen, K. V., Villadsen, J. & Nilsson, D., 1999, In : Metabolic Engineering. 1, p. E17-E24

Research output: Contribution to journalJournal articleResearchpeer-review

On the optimal design and control of a biodegradation process with substrate inhibition kinetics

Villadsen, J., 1999, In : Industrial & Engineering Chemistry Research. 38, p. 660-666

Research output: Contribution to journalJournal articleResearchpeer-review

Quantification of intracellular metabolic fluxes from fractional enrichment measurements and isotopomer analysis of 13C labelled biomass components

Schmidt, K., Nørregaard, L. C., Pedersen, B., Meissner, A., Duus, J. Ø., Nielsen, J. B. & Villadsen, J., 1999, In : Metabolic Engineering. 1, p. 166-179

Research output: Contribution to journalJournal articleResearchpeer-review

1998

C-13 Tracer experiments and metabolite balancing for metabolic flux analysis: Comparing two approaches

Schmidt, K., Marx, A., de Graaf, A. A., Wiechert, W., Sahm, H., Nielsen, J. B. & Villadsen, J., 1998, In : Biotechnology and Bioengineering. 58, 2-3, p. 254-257

Research output: Contribution to journalJournal articleResearchpeer-review

Cyclization of alpha-aminoadipic acid into the beta-lactam 6-oxo-piperidine-2-carboxylic acid by Penicillium chrysogenum

Henriksen, C. M., Nielsen, J. B. & Villadsen, J., 1998, In : The Journal of Antibiotics. 51, p. 99-106

Research output: Contribution to journalJournal articleResearchpeer-review

High exogeneous concentrations of phenoxyacetic acid are crucial for a high penicillin V productivity in Penicillium chrysogenum

Henriksen, C. M., Nielsen, J. B. & Villadsen, J., 1998, In : Microbiology. 144, p. 2001-2006

Research output: Contribution to journalJournal articleResearchpeer-review

Modelling of the protonophoric uncoupling by phenoxyacetic acid of the plasma membrane of Penicillium chrysogenum

Henriksen, C. M., Nielsen, J. B. & Villadsen, J., 1998, In : Biotechnology and Bioengineering. 60, 6, p. 761-767

Research output: Contribution to journalJournal articleResearchpeer-review

On-line study of fungal morphology during submerged growth in a small flow-through cell.

Spohr, A. B., Dam Mikkelsen, C., Carlsen, M., Nielsen, J. B. & Villadsen, J., 1998, In : Biotechnology and Bioengineering. 58, 5, p. 541-553

Research output: Contribution to journalJournal articleResearchpeer-review

Simple generic model for dynamic experiments with Saccharomyces cerevisiae in continuous culture. Decoupling between anabolism and catabolism.

Duboc, P. J., von Stockar, U. & Villadsen, J., 1998, In : Biotechnology and Bioengineering. 60, 2, p. 180-189

Research output: Contribution to journalJournal articleResearchpeer-review

1997

Flux distributions in anaerobic, glucose-limited continous cultures of Saccharomyces cerevisiae

Nissen, T. L., Schulze, U., Nielsen, J. B. & Villadsen, J., 1997, In : Microbiology. 143, p. 203-218

Research output: Contribution to journalJournal articleResearchpeer-review

Influence of the dissolved oxygen concentration on the penicillin biosynthetic pathway in steady-state cultures of Penicillium chrysogenum

Henriksen, C. M., Nielsen, J. B. & Villadsen, J., 1997, In : Biotechnology Progress. 13, 6, p. 776-82

Research output: Contribution to journalJournal articleResearchpeer-review

Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid

Henriksen, C. M., Holm, SS., Schipper, D., Jørgensen, HS., Nielsen, J. B. & Villadsen, J., 1997, In : Process Biochemistry. 32, 2, p. 85-91

Research output: Contribution to journalJournal articleResearchpeer-review

Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices

Schmidt, K., Carlsen, M., Nielsen, J. B. & Villadsen, J., 1997, In : Biotechnology and Bioengineering (Print). 55, 6, p. 831-840

Research output: Contribution to journalJournal articleResearchpeer-review

Morphological characterization of recombinant strains of Aspergillus oryzae producing alpha-amylase during batch cultivations

Spohr, A. B., Carlsen, M., Nielsen, J. B. & Villadsen, J., 1997, In : Biotechnology Letters. 19, 3, p. 257-261

Research output: Contribution to journalJournal articleResearchpeer-review

Putting structure into Chemical Engineering. Proceedings of an industry/university conference

Villadsen, J., 1997, In : Chemical Engineering Science. 52, 17, p. 2857-2864

Research output: Contribution to journalJournal articleResearchpeer-review

1996

Amino acid utilization by Lactococcus lactis subsp cremoris FD1 during growth on yeast extract or casein peptone

Benthin, S. & Villadsen, J., 1996, In : Journal of Applied Bacteriology. 80, p. 65-72

Research output: Contribution to journalJournal articleResearch

Dynamics of ammonia uptake in nitrogen limited anaerobic cultures of Saccharomyces cerevisiae

Schulze, U., Liden, G. & Villadsen, J., 1996, In : Journal of Biotechnology. 46, p. 33-42

Research output: Contribution to journalJournal articleResearchpeer-review

Growth and alpha-amylase production by Aspergillus oryzae

Carlsen, M., Nielsen, J. B. & Villadsen, J., 1996, In : Journal of Biotechnology. 45, p. 81-93

Research output: Contribution to journalJournal articleResearchpeer-review

Growth and alpha-amylase production by Aspergillus oryzae during continous cultivations.

Carlsen, M., Nielsen, J. B. & Villadsen, J., 1996, In : Journal of Biotechnology. 45, p. 81-93

Research output: Contribution to journalJournal articleResearchpeer-review