Publications per year
Publications per year
Personal profile
Profile
John M. Woodley is a bioprocess engineer who has had an interest in the biological synthesis of useful chemicals, using biocatalysis and fermentation for that last 30 years. His research is at the interface of bioprocess engineering, process chemistry and reaction engineering. It includes both theoretical and experimental work at different scales:
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Multi-step biocatalysis, including systems biocatalysis and flow chemistry
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Downstream processing from biocatalytic reactors and fermentations, including ISPR
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Modelling tools for the assessment of bioprocesses, including thermodynamics, kinetics, process simulation, economic evaluation
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Bio-oxidations, including oxygen supply methods
Enzymes currently under investigation include alcohol oxidases, carbohydrate oxidases, cytochrome P450s, Baeyer-Villiger monooxygenases and transaminases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- User defined:
- enzymatic synthesis of pharmaceuticals
- chemicals from renewable resources
- Enzyme and bioprocess technology
- enzyme kinetics
- biocatalytic reactor design
- bioprocess design
- chemo-enzymatic synthesis
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Collaborations and top research areas from the last five years
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Publications
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A novel strategy for extraction of intracellular poly(3-hydroxybutyrate) from engineered Pseudomonas putida using deep eutectic solvents: Comparison with traditional biobased organic solvents
Didion, Y. P., Vargas, M. V. G. A., Tjaslma, T. G., Woodley, J., Nikel, P. I., Malankowska, M., Su, Z. & Pinelo, M., 2024, In: Separation and Purification Technology. 338, 14 p., 126465.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile56 Downloads (Pure) -
Biocatalysis in microfluidic systems: an experimental basis for data science
Woodley, J. M., 2024, In: Reaction Chemistry and Engineering. 9, p. 2028-2033Research output: Contribution to journal › Review › peer-review
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Biocatalysis with In-Situ Product Removal Improves p-Coumaric Acid Production
Virklund, A., Nielsen, A. T. & Woodley, J. M., 2024, (Accepted/In press) In: ChemBioChem.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Effect of backwash as a strategy for biofouling control in the submerged ceramic membrane bioreactor for high-density cultivations: Process optimization and fouling mechanism at pilot scale
Jankowska, K., Domingo-Félez, C., Andres Prado-Rubio, O., Skiadas, I. V., Woodley, J. M. & Pinelo, M., 2024, In: Separation and Purification Technology. 338, 13 p., 126428.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile53 Downloads (Pure) -
Genetic heterogeneity of engineered Escherichia coli Nissle 1917 strains during scale-up simulation
Munkler, L. P., Mohamed, E. T., Vazquez-Uribe, R., Visby Nissen, V., Rugbjerg, P., Worberg, A., Woodley, J. M., Feist, A. M. & Sommer, M. O. A., 2024, In: Metabolic Engineering. 85, p. 159-166Research output: Contribution to journal › Journal article › Research › peer-review
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Integrated model for up- and downstream bioprocess intensification
Pfaff, D. (PhD Student), Woodley, J. (Main Supervisor), Kager, J. (Supervisor), Ruiz, J. L. M. (Supervisor) & Yang, L. (Supervisor)
01/09/2024 → 31/08/2027
Project: PhD
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P450-based biocatalytic processes for the pharmaceutical industry
Pappa, E. I. (PhD Student), Erdem, E. (Main Supervisor), Woodley, J. (Main Supervisor) & Gillam, E. (Main Supervisor)
01/07/2024 → 30/06/2027
Project: PhD
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Advancing the Scaling up on the Implementation of Novel, Hybrid Downstream Processes
Karki, R. (PhD Student), Pinelo, M. (Main Supervisor), Skiadas, I. V. (Supervisor) & Woodley, J. (Supervisor)
01/06/2024 → 31/05/2027
Project: PhD
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ENFACE: A tool for prediction of enzyme stability at gas-liquid interfaces based on computational methods
Høvring, J. F. (PhD Student), Peters, G. H. J. (Main Supervisor), Woodley, J. (Supervisor) & Brask, J. (Supervisor)
01/03/2024 → 28/02/2027
Project: PhD
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Enzyme Biofoundry: Machine learning for multiparametric enzyme & biocatalytic process optimization
Edin, M. (PhD Student), Acevedo-Rocha, C. G. (Main Supervisor), Mansouri, S. S. (Supervisor) & Woodley, J. (Supervisor)
01/03/2024 → 28/02/2027
Project: PhD
Activities
- 10 Conference presentations
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High Kinetic Stability of an Engineered Alcohol Dehydrogenase for Biocatalytic Oxidation process
Wang, J. (Speaker), Tian, W. (Other), Qu, X. (Other) & Woodley, J. (Other)
10 Jul 2022 → 15 Jul 2022Activity: Talks and presentations › Conference presentations
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Enzyme Stability at Gas-Liquid Interface under Various Oxygen Concentration in Biocatalytic Oxidation Process
Wang, J. (Speaker), Tian, W. (Other), Erdem, E. (Other), Qu, X. (Other) & Woodley, J. (Other)
25 Oct 2022 → 26 Oct 2022Activity: Talks and presentations › Conference presentations
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CFD-kinetic Modelling for the Scale-up of P. putida Fed-batch Fermentations
Jamshidzadeh, M. (Speaker), Jensen, J. W. (Other), Krühne, U. (Other), Woodley, J. (Other), Nikel, P. I. (Other) & Junicke, H. (Other)
29 Mar 2022Activity: Talks and presentations › Conference presentations
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Scale Up/Down of Fed-Batch Fermentation Processes: Application of Discrete Phase Modelling
Jamshidzadeh, M. (Speaker), Jensen, J. W. (Other), Ursela Griesz, A. (Other), Krühne, U. (Other), Woodley, J. (Other), Nikel, P. I. (Other) & Junicke, H. (Other)
18 Oct 2022Activity: Talks and presentations › Conference presentations
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Enzyme Stability Under Different Oxidative Stress in Biocatalytic Oxidation Process
Wang, J. (Speaker) & Woodley, J. (Other)
28 Aug 2022 → 1 Sept 2022Activity: Talks and presentations › Conference presentations
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