• Kogle Allé 6, Cederhuset, xx

    2970 Hørsholm

    Denmark

20152020

Research output per year

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Research Output

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Journal article
2017

Cyanobacterial carbon metabolism: Fluxome plasticity and oxygen dependence

Wan, N., Delorenzo, D. M., He, L., You, L., Immethun, C. M., Wang, G., Baidoo, E. E. K., Hollinshead, W. D., Keasling, J. D., Moon, T. S. & Tang, Y. J., 2017, In : Biotechnology and Bioengineering. 114, 7, p. 1593-1602

Research output: Contribution to journalJournal articleResearchpeer-review

Deciphering flux adjustments of engineered E. coli cells during fermentation with changing growth conditions

He, L., Xiu, Y., Jones, J. A., Baidoo, E. E. K., Keasling, J. D., Tang, Y. J. & Koffas, M. A. G., 2017, In : Metabolic Engineering. 39, p. 247–256 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Development of an integrated approach for α-pinene recovery and sugar production from loblolly pine using ionic liquids

Papa, G., Kirby, J., Murthy Konda, N. V. S. N., Tran, K., Singh, S., Keasling, J. D., Peter, G. F. & Simmons, B. A., 2017, In : Green Chemistry. 19, p. 1117-1127

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

Development of a Transcription Factor-Based Lactam Biosensor

Zhang, J., Barajas, J. F., Burdu, M., Ruegg, T. L., Dias, B. & Keasling, J., 2017, In : A C S Synthetic Biology. 6, 3, p. 439-445

Research output: Contribution to journalJournal articleResearchpeer-review

Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae

Phelan, R. M., Sachs, D., Petkiewicz, S. J., Barajas, J. F., Blake-Hedges, J. M., Thompson, M. G., Apel, A. R., Rasor, B. J., Katz, L. & Keasling, J. D., 2017, In : A C S Synthetic Biology. 6, 1, p. 159-166

Research output: Contribution to journalJournal articleResearchpeer-review

Engineered polyketides: Synergy between protein and host level engineering

Barajas, J. F., Blake-Hedges, J. M., Bailey, C. B., Curran, S. & Keasling, J. D., 2017, In : Synthetic and Systems Biotechnology. 2, 3, p. 147-166

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
185 Downloads (Pure)

Engineering glucose metabolism of escherichia coli under nitrogen starvation

Chubukov, V., Desmarais, J. J., Wang, G., Chan, L. J. G., Baidoo, E. E. K., Petzold, C. J., Keasling, J. D. & Mukhopadhyay, A., 2017, In : n p j Systems Biology and Applications. 3, 1, 7 p., 16035.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
23 Downloads (Pure)

Engineering high-level production of fatty alcohols by Saccharomyces cerevisiae from lignocellulosic feedstocks

d'Espaux, L., Ghosh, A., Runguphan, W., Wehrs, M., Xu, F., Konzock, O., Dev, I., Nhan, M., Gin, J., Apel, A. R., Petzold, C. J., Singh, S., Simmons, B. A., Mukhopadhyay, A., Martín, H. G. & Keasling, J. D., 2017, In : Metabolic Engineering. 42, p. 115-125

Research output: Contribution to journalJournal articleResearchpeer-review

Flux-Enabled Exploration of the Role of Sip1 in galactose yeast metabolism

Shymansky, C. M., Wang, G., Baidoo, E. E. K., Gin, J., Apel, A. R., Mukhopadhyay, A., Martin, H. G. & Keasling, J., 2017, In : Frontiers in Bioengineering and Biotechnology. 5, 13 p., 31.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
148 Downloads (Pure)

Heterologous Gene Expression of N-Terminally Truncated Variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular Polyketide Synthase

Yuzawa, S., Bailey, C. B., Fujii, T. A., Jocic, R., Barajas, J. F., Benites, V. T., Baidoo, E. E. K., Chen, Y., Petzold, C. J., Katz, L. & Keasling, J. D., 2017, In : A C S Chemical Biology. 12, 11, p. 2725-2729 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

High-throughput enzyme screening platform for the IPP-bypass mevalonate pathway for isopentenol production

Kang, A., Meadows, C. W., Canu, N., Keasling, J. D. & Lee, T. S., 2017, In : Metabolic Engineering. 41, p. 125-134

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
171 Downloads (Pure)

Intracellular cellobiose metabolism and its applications in lignocellulose-based biorefineries

Parisutham, V., Chandran, S-P., Mukhopadhyay, A., Lee, S. K. & Keasling, J. D., 2017, In : Bioresource Technology. 239, p. 496-506

Research output: Contribution to journalJournal articleResearchpeer-review

Lipid engineering reveals regulatory roles for membrane fluidity in yeast flocculation and oxygen-limited growth

Degreif, D., de Rond, T., Bertl, A., Keasling, J. D. & Budin, I., 2017, In : Metabolic Engineering. 41, p. 46-56

Research output: Contribution to journalJournal articleResearchpeer-review

OpenMSI Arrayed Analysis Toolkit: Analyzing Spatially Defined Samples Using Mass Spectrometry Imaging

de Raad, M., de Rond, T., Rübel, O., Keasling, J., Northen, T. R. & Bowen, B. P., 2017, In : Analytical chemistry. 89, 11, p. 5818-5823

Research output: Contribution to journalJournal articleResearchpeer-review

Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme

de Rond, T., Stow, P., Eigl, I., Johnson, R. E., Chan, L. J. G., Goyal, G., Baidoo, E. E. K., Hillson, N. J., Petzold, C. J., Sarpong, R. & Keasling, J. D., 2017, In : Nature Chemical Biology. 13, 11, p. 1155-1157

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
138 Downloads (Pure)

Production of jet fuel precursor monoterpenoids from engineered Escherichia coli

Mendez-Perez, D., Alonso-Gutierrez, J., Hu, Q., Molinas, M., Baidoo, E. E. K., Wang, G., Chan, L. J. G., Adams, P. D., Petzold, C. J., Keasling, J. D. & Lee, T. S., 2017, In : Biotechnology and Bioengineering. 114, 8, p. 1703-1712

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
202 Downloads (Pure)

System-level perturbations of cell metabolism using CRISPR/Cas9

Jakociunas, T., Jensen, M. K. & Keasling, J., 2017, In : Current Opinion in Biotechnology. 46, p. 134-140

Research output: Contribution to journalJournal articleResearchpeer-review

The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization

Morell, W. C., Birkel, G. W., Forrer, M., Lopez, T., Backman, T. W. H., Dussault, M., Petzold, C. J., Baidoo, E. E. K., Costello, Z., Ando, D., Alonso-Gutierrez, J., George, K. W., Mukhopadhyay, A., Vaino, I., Keasling, J., Adams, P. D., Hillson, N. J. & Garcia Martin, H., 2017, In : A C S Synthetic Biology. 6, 12, p. 2248-2259 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
135 Downloads (Pure)

The JBEI quantitative metabolic modeling library (jQMM): a python library for modeling microbial metabolism

Birkel, G. W., Ghosh, A., Kumar, V. S., Weaver, D., Ando, D., Backman, T. W. H., Arkin, A. P., Keasling, J. D. & Martin, H. G., 2017, In : B M C Bioinformatics. 18, 11 p., 205.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
184 Downloads (Pure)

Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies

Damgaard Jensen, E., Ferreira, R., Jakociunas, T., Arsovska, D., Zhang, J., Ding, L., Smith, J. D., David, F., Nielsen, J., Jensen, M. K. & Keasling, J. D., 2017, In : Microbial Cell Factories. 16, 16 p., 46.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
300 Downloads (Pure)
2016

13C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids

Ghosh, A., Ando, D., Gin, J., Runguphan, W., Denby, C., Wang, G., Baidoo, E. E. K., Shymansky, C., Keasling, J. & García Martín, H., 2016, In : Frontiers in Bioengineering and Biotechnology. 4, 10 p., 76.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
259 Downloads (Pure)

CRISPR/Cas9 advances engineering of microbial cell factories

Jakociunas, T., Jensen, M. K. & Keasling, J. D., 2016, In : Metabolic Engineering. 34, p. 44-59 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes into Saccharomyces cerevisiae via CRISPR-Cas9

Fabre, M. M. J., Jakociunas, T., Stovicek, V., Dai, Z., Jensen, M. K., Keasling, J. & Borodina, I., 2016, In : Biotechnology Journal. 11, 8, p. 1110-1117 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
737 Downloads (Pure)

Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae

Kirby, J., Dietzel, K. L., Wichmann, G., Chan, R., Antipov, E., Moss, N., Baidoo, E. E. K., Jackson, P., Gaucher, S. P., Gottlieb, S., LaBarge, J., Mahatdejkul, T., Hawkins, K. M., Muley, S., Newman, J. D., Liu, P., Keasling, J. & Zhao, L., 2016, In : Metabolic Engineering. 38, p. 494-503 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Engineering an NADPH/NADPRedox Biosensor in Yeast

Zhang, J., Sonnenschein, N., Pihl, T. P. B., Pedersen, K. R., Jensen, M. K. & Keasling, J., 2016, In : A C S Synthetic Biology. 5, 12, p. 1546–1556 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Engineering Bacteria to Catabolize the Carbonaceous Component of Sarin: Teaching E. coli to Eat Isopropanol

Brown, M. E., Mukhopadhyay, A. & Keasling, J. D., 2016, In : A C S Synthetic Biology. 5, 12, p. 1485-1496 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Engineering of synthetic, stress-responsive yeast promoters

Rajkumar, A. S., Liu, G., Bergenholm, D., Arsovska, D., Kristensen, M., Nielsen, J., Jensen, M. K. & Keasling, J., 2016, In : Nucleic acids research. 44, 17, 12 p., e136.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
297 Downloads (Pure)

Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast

Skjødt, M. L., Snoek, T., Kildegaard, K. R., Arsovska, D., Eichenberger, M., Goedecke, T. J., Rajkumar, A. S., Zhang, J., Kristensen, M., Lehka, B., Siedler, S., Borodina, I., Jensen, M. K. & Keasling, J., 2016, In : Nature Chemical Biology. 12, 11, p. 951-958 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Enhanced fatty acid production in engineered chemolithoautotrophic bacteria using reduced sulfur compounds as energy sources

Beller, H. R., Zhou, P., Jewell, T. N. M., Goh, E-B. & Keasling, J., 2016, In : Metabolic Engineering Communications. 3, p. 211-215 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
399 Downloads (Pure)

Examining Escherichia coli glycolytic pathways, catabolite repression, and metabolite channeling using Δpfk mutants

Hollinshead, W. D., Rodriguez, S., Martin, H. G., Wang, G., Baidoo, E. E. K., Sale, K. L., Keasling, J., Mukhopadhyay, A. & Tang, Y. J., 2016, In : Biotechnology for Biofuels. 9, 13 p., 212.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
201 Downloads (Pure)

Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast

Eudes, A., Mouille, M., Robinson, D. S., Benites, V. T., Wang, G., Roux, L., Tsai, Y-L., Baidoo, E. E. K., Chiu, T-Y., Heazlewood, J. L., Scheller, H. V., Mukhopadhyay, A., Keasling, J. D., Deutsch, S. & Loque, D., 2016, In : Microbial Cell Factories. 15, 16 p., 198.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
116 Downloads (Pure)

In vitro Characterization of Phenylacetate Decarboxylase, a Novel Enzyme Catalyzing Toluene Biosynthesis in an Anaerobic Microbial Community

Zargar, K., Saville, R., Phelan, R. M., Tringe, S. G., Petzold, C. J., Keasling, J. & Beller, H. R., 2016, In : Scientific Reports. 6, 10 p., 31362.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
147 Downloads (Pure)
2015

CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae

Jakociunas, T., Rajkumar, A. S., Zhang, J., Arsovska, D., Rodriguez Prado, E. A., Jendresen, C. B., Skjødt, M. L., Nielsen, A. T., Borodina, I., Jensen, M. K. & Keasling, J., 2015, In : A C S Synthetic Biology. 4, 11, p. 1226-1234 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae

Ronda, C., Maury, J., Jakociunas, T., Jacobsen, S. A. B., Germann, S. M., Harrison, S. J., Borodina, I., Keasling, J. D., Jensen, M. K. & Nielsen, A. T., 2015, In : Microbial Cell Factories. 14, 97, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
427 Downloads (Pure)

Development of biosensors and their application in metabolic engineering

Zhang, J., Jensen, M. K. & Keasling, J., 2015, In : Current Opinion in Chemical Biology. 28, 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

Jakociunas, T., Bonde, I., Herrgard, M., Harrison, S. J., Kristensen, M., Pedersen, L. E., Jensen, M. K. & Keasling, J., 2015, In : Metabolic Engineering. 28, p. 213-222 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Recent applications of synthetic biology tools for yeast metabolic engineering

Jensen, M. K. & Keasling, J., 2015, In : FEMS Yeast Research. 15, 1, 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review