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Research Output

2019

Nucleotide metabolism

Martinussen, J., Willemoes, M. & Kilstrup, M., 2019, Comprehensive Biotechnology. Moo-Young, M. (ed.). 3rd ed. Elsevier, Vol. 1. p. 69-84 16 p.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

2018

Interplay Between Capsule Expression and Uracil Metabolism in Streptococcus pneumoniae D39

Carvalho, S. M., Kloosterman, T. G., Manzoor, I., Caldas, J., Vinga, S., Martinussen, J., Saraiva, L. M., Kuipers, O. P. & Neves, A. P., 2018, In : Frontiers in Microbiology. 9, 15 p., 321.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
206 Downloads (Pure)
2017

Metabolic characterization and transformation of the non-dairy Lactococcus lactis strain KF147, for production of ethanol from xylose

Petersen, K. V., Liu, J., Chen, J., Martinussen, J., Jensen, P. R. & Solem, C., 2017, In : Biotechnology Journal. 12, 8, 12 p., 1700171 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
288 Downloads (Pure)

Phosphoribosyl Diphosphate (PRPP): Biosynthesis, Enzymology, Utilization, and Metabolic Significance

Hove-Jensen, B., Andersen, K. R., Kilstrup, M., Martinussen, J., Switzer, R. L. & Willemoes, M., 2017, In : Microbiology and Molecular Biology Reviews. 81, 1, 83 p., e00040-16.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
812 Downloads (Pure)
2016

Ribosomal dimerization factor YfiA is the major protein synthesized after abrupt glucose depletion in Lactococcus lactis

Breuner, A., Frees, D., Varmanen, P., Boguta, A. M., Hammer, K., Martinussen, J. & Kilstrup, M., 2016, In : Microbiology. 162, p. 1829-1839

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
254 Downloads (Pure)
2015

Bacillus halodurans Strain C125 Encodes and Synthesizes Enzymes from Both Known Pathways To Form dUMP Directly from Cytosine Deoxyribonucleotides

Oehlenschlæger, C. B., Løvgreen, M. N., Reinauer, E., Lehtinen, E., Pind, M-L. L., Harris, P., Martinussen, J. & Willemoës, M., 2015, In : APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 81, 10, p. 3395-3404 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Bistability in a Metabolic Network Underpins the De Novo Evolution of Colony Switching in Pseudomonas fluorescens

Gallie, J., Libby, E., Bertels, F., Remigi, P., Jendresen, C. B., Ferguson, G. C., Desprat, N., Buffing, M. F., Sauer, U., Beaumont, H. J. E., Martinussen, J., Kilstrup, M. & Rainey, P. B., 2015, In : P L o S Biology. 13, 3, 28 p., e1002109.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
345 Downloads (Pure)

Development of a real-time PCR method coupled with a selective pre-enrichment step for quantification of Morganella morganii and Morganella psychrotolerans in fish products

Podeur, G., Dalgaard, P., Leroi, F., Prevost, H., Emborg, J., Martinussen, J., Hansen, L. H. & Filet, M-F., 2015, In : International Journal of Food Microbiology. 203, p. 55-62 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2014

Multi-stress resistance in Lactococcus lactis is actually escape from purine-induced stress sensitivity

Ryssel, M., Hviid, A-M. M., Dawish, M. S., Haaber, J., Hammer, K., Martinussen, J. & Kilstrup, M., 2014, In : Microbiology. 160, 11, p. 2551-2559 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Screening of lactic acid bacteria for their potential as microbial cell factories for bioconversion of lignocellulosic feedstocks

Boguta, A. M., Bringel, F., Martinussen, J. & Jensen, P. R., 2014, In : Microbial Cell Factories. 13, 1, 16 p., 97.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
287 Downloads (Pure)

Towards in vivo regulon kinetics: PurR activation by 5-phosphoribosyl-a-1-pyrophosphate during purine depletion in Lactococcus lactis.

Jendresen, C. B., Dimitrov, P., Gautier, L., Lui, M., Martinussen, J. & Kilstrup, M., 2014, In : Microbiology-Sgm. 160, 7, p. 1321-1331

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Détection et quantification de Morganella psychrotolerans dans des poissons par qPCR.

Translated title of the contribution: Détection et quantification de Morganella psychrotolerans dans des poissons par qPCR.Podeur, G., Leroi, F., Prevost, H., Pilet, M. F., Dalgaard, P., Emborg, J., Martinussen, J. & Hansen, L., 2013. 2 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
54 Downloads (Pure)

Dispersive solid phase extraction combined with ion-pair ultra high-performance liquid chromatography tandem mass spectrometry for quantification of nucleotides in Lactococcus lactis

Magdenoska, O., Martinussen, J., Thykær, J. & Nielsen, K. F., 2013, In : Analytical Biochemistry. 440, 2, p. 166-177

Research output: Contribution to journalJournal articleResearchpeer-review

Engineering strategies aimed at control of acidification rate of lactic acid bacteria

Martinussen, J., Solem, C., Holm, A. K. & Jensen, P. R., 2013, In : Current Opinion in Biotechnology. 24, 2, p. 124-129

Research output: Contribution to journalJournal articleResearchpeer-review

Repetitive, Marker-Free, Site-Specific Integration as a Novel Tool for Multiple Chromosomal Integration of DNA

Petersen, K. V., Martinussen, J., Jensen, P. R. & Solem, C., 2013, In : Applied and Environmental Microbiology. 79, 12, p. 3563-3569

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
317 Downloads (Pure)
2012

Evaluation of cell factory performance through determination of intracellular metabolites using LC-MS/MS

Magdenoska, O., Martinussen, J., Nielsen, K. F. & Thykær, J., 2012, In : New Biotechnology. 29S

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
File
231 Downloads (Pure)

The PurR regulon in Lactococcus lactis – transcriptional regulation of the purine nucleotide metabolism and translational machinery

Jendresen, C. B., Martinussen, J. & Kilstrup, M., 2012, In : Microbiology. 158, 8, p. 2026-38

Research output: Contribution to journalJournal articleResearchpeer-review

File
93 Downloads (Pure)
2011

Experimental methods and modeling techniques for description of cell population heterogeneity

Lencastre Fernandes, R., Nierychlo, M., Lundin, L., Pedersen, A. E., PuentesTellez, P. E., Dutta, A., Carlqvist, M., Bolic, A., Schäpper, D., Brunetti, A. C., Helmark, S., Heins, A-L., Jensen, A. D., Nopens, I., Rottwitt, K., Szita, N., van Elsas, J. D., Nielsen, P. H., Martinussen, J., Sørensen, S. J. & 2 others, Eliasson Lantz, A. & Gernaey, K., 2011, In : Biotechnology Advances. 29, 6, p. 575-599

Research output: Contribution to journalJournal articleResearchpeer-review

Nucleotide Metabolism

Martinussen, J., Willemoës, M. & Kilstrup, M., 2011, Comprehensive Biotechnology. Moo-Young, M. (ed.). 2 ed. Elsevier, Vol. 1. p. 91-107

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2010

Two nucleoside transporters in Lactococcus lactis with different substrate specificities

Martinussen, J., Sørensen, C., Jendresen, C. B. & Kilstrup, M., 2010, In : Microbiology. 156, p. 3148-3157

Research output: Contribution to journalJournal articleResearchpeer-review

Strains of Lactococcus lactis with a partial pyrimidine requirement show sensitivity toward aspartic acid

Wadskov-Hansen, S. L. L. & Martinussen, J., 2009, In : Le Lait (Print). 89, 2, p. 125-137

Research output: Contribution to journalJournal articleResearchpeer-review

2008

Activation of purine biosynthetic gene expression by PurR in Lactococcus lactis

Jendresen, C. B., Kilstrup, M. & Martinussen, J., 2008.

Research output: Contribution to conferencePosterResearchpeer-review

Transcriptome analysis of the Lactococcus lactis ArgR and AhrC regulons

Larsen, R., van Hijum, S. A. F. T., Martinussen, J., Kuipers, O. P. & Kok, J., 2008, In : Applied and Environmental Microbiology. 74, 15, p. 4768-4771

Research output: Contribution to journalJournal articleResearchpeer-review

2007

Analysis of plasmid pDBORO – A plasmid encoding an orotate transporter from Lactococcus lactis subsp. lactis biovar. diacetylactis strain DB0410

Martinussen, J. & Defoor, E. M. C., 2007.

Research output: Contribution to conferenceConference abstract for conferenceResearch

Purine nucleosides and Cytidine uptake in Lactococcus lactis share a common transporter of the ABC type

Martinussen, J., 2007.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

The orotate transporter encoded by oroP from Lactococcus lactis is required for orotate utilization and is functional in both Gram-positive and Gram-negative bacteria

Defoor, E., Kryger, M. & Martinussen, J., 2007, In : Microbiology. 153, p. 3645-3659

Research output: Contribution to journalJournal articleResearchpeer-review

2006

Expression of the pyr operon of Lactobacillus plantarum is regulated by inorganic carbon availability through a second regulator, PyrR2, homologous to the pyrimidine-dependent regulator PyrR1

Arsène-Ploetze, F., Valérie Kugler, V., Martinussen, J. & Bringel, F., 2006, In : Journal of Bacteriology. 188, 24, p. 8607-8616

Research output: Contribution to journalJournal articleResearchpeer-review

The orotate transporter oroP from Lactococcus lactis is required for orotate uptake and can be used both as a food-grade selection and counter-selection marker

Defoor, E. M. C. & Martinussen, J., 2006.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Uracil Salvage Pathway in Lactobacillus plantarum: Transcription and Genetic Studies

Arséne-Ploetzel, F., Nicoloff, H., Kammerer, B., Martinussen, J. & Bringel, F., 2006, In : Journal of Bacteriology. 188, 13, p. 4777-4786

Research output: Contribution to journalJournal articleResearchpeer-review

2005

Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity

Willemoës, M., Mølgaard, A., Johansson, E. & Martinussen, J., 2005, In : F E B S Journal. 272, 3, p. 856-864

Research output: Contribution to journalJournal articleResearchpeer-review

Nucleotide Metabolism and its Control in Lactic Acid Bacteria

Kilstrup, M., Hammer, K., Jensen, P. R. & Martinussen, J., 2005, In : F E M S Microbiology Reviews. 29, p. 555-590

Research output: Contribution to journalJournal articleResearchpeer-review

Nucleotide Sequence and Analysis of an orotate transporter-containing plasmid isolated from the Lactococcus lactis ssp. lactis biovar diacetylactis strain DB0410

Defoor, E. M. C. & Martinussen, J., 2005.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Orotate Transporter Encoding marker Genes

Defoor, E. M. C. & Martinussen, J., 2005, Patent No. PCT/2005/000092, 11 Feb 2005

Research output: Patent

Purine and Cytidine uptake in Lacococcus lactis share a common transporter of the ABC type

Martinussen, J. & Sørensen, C., 2005.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Repression of the pyr operon in Lactobacillus plantarum prevents its ability to grow at low carbon dioxide levels

Nicoloff, H., Elagöz, A., Arsène-Ploetze, F., Kammerer, B., Martinussen, J. & Bringel, F., 2005, In : Journal of Bacteriology. 187, 6, p. 2093-2104

Research output: Contribution to journalJournal articleResearchpeer-review

2004

Addition of alpha-ketoglutarate enhances formation of volatiles by Staphylococcus carnosus during sausage fermentation

Tjener, K., Stahnke, L. H., Andersen, L. & Martinussen, J., 2004, In : Meat Science. 67, p. 711-719

Research output: Contribution to journalJournal articleResearchpeer-review

Expression of the pyrG gene determines the pool sizes of CTP and dCTP in Lactococcus lactis

Jørgensen, C. M., Hammer, K., Jensen, P. R. & Martinussen, J., 2004, In : European Journal of Biochemistry. 271, p. 2438-2445

Research output: Contribution to journalJournal articleResearchpeer-review

Growth and production of volatiles by Staphylococcus carnosus in dry sausages: nfluence of inoculation level and ripening time

Tjener, K., Stahnke, L. H., Andersen, L. & Martinussen, J., 2004, In : Meat Science. 67, p. 447-452

Research output: Contribution to journalJournal articleResearchpeer-review

The pH-unrelated influence of salt, temperature and manganese on aroma formation by Staphylococcus xylosus and Staphylococcus carnosus in a fermented meat model system

Tjener, K., Stahnke, L. H., Andersen, L. & Martinussen, J., 2004, In : International Journal of Food Microbiology. 97, p. 31-42

Research output: Contribution to journalJournal articleResearchpeer-review

2003

A fermented meat model system for studies of microbial aroma formation

Tjener, K., Stahnke, L. H., Andersen, L. & Martinussen, J., 2003, In : Meat Science. 66, 1, p. 211-218

Research output: Contribution to journalJournal articleResearchpeer-review

CTP limitation increases expression of CTP synthase in Lactococcus lactis

Jørgensen, C. M., Hammer, K. & Martinussen, J., 2003, In : Journal of Bacteriology. 185, 22, p. 6562-6574

Research output: Contribution to journalJournal articleResearchpeer-review

Two nucleoside uptake systems in Lactococcus lactis: Competition between purine nucleosides and cytidine allows for modulation of intracellular nucleotide pools

Martinussen, J., Wadskov-Hansen, S. L. L. & Hammer, K., 2003, In : Journal of Bacteriology. 185, 5, p. 1503-1508

Research output: Contribution to journalJournal articleResearchpeer-review