20042021

Research output per year

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Research Output

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Journal article
2019
Open Access
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21 Downloads (Pure)
2018

Efficient Oligo nucleotide mediated CRISPR-Cas9 Gene Editing in Aspergilli

Nødvig, C. S., Hoof, J. B., Kogle, M. E., Jarczynska, Z. D., Lehmbeck, J., Klitgaard, D. K. & Mortensen, U. H., 2018, In : Fungal Genetics and Biology. 115, p. 78-89

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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300 Downloads (Pure)

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri

Vesth, T. C., Nybo, J. L., Theobald, S., Frisvad, J. C., Larsen, T. O., Nielsen, K. F., Hoof, J. B., Brandl, J., Salamov, A., Riley, R., Gladden, J. M., Phatale, P., Nielsen, M. T., Lyhne, E. K., Kogle, M. E., Strasser, K., McDonnell, E., Barry, K., Clum, A., Chen, C. & 19 others, LaButti, K., Haridas, S., Nolan, M., Sandor, L., Kuo, A., Lipzen, A., Hainaut, M., Drula, E., Tsang, A., Magnuson, J. K., Henrissat, B., Wiebenga, A., Simmons, B. A., Mäkelä, M. R., de Vries, R. P., Grigoriev, I. V., Mortensen, U. H., Baker, S. E. & Andersen, M. R., 2018, In : Nature Genetics. 50, p. 1688–1695

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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227 Downloads (Pure)

Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication

Theobald, S., Vesth, T. C., Rendsvig, J. K., Nielsen, K. F., Riley, R., de Abreu, L. M., Salamov, A., Frisvad, J. C., Larsen, T. O., Andersen, M. R. & Hoof, J. B., 2018, In : Scientific Reports. 8, 12 p., 17957.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
194 Downloads (Pure)
2017

Genes Linked to Production of Secondary Metabolites in Talaromyces atroroseus Revealed Using CRISPR-Cas9

Nielsen, M. L., Petersen, T. I., Rasmussen, K. B., Thrane, U., Hoof, J. B., Larsen, T. O. & Mortensen, U. H., 2017, In : P L o S One. 12, 1, 9 p., e0169712.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
323 Downloads (Pure)
2016

Diversity in Secondary Metabolites Including Mycotoxins from Strains of Aspergillus Section Nigri Isolated from Raw Cashew Nuts from Benin, West Africa

Lamboni, L. Y., Nielsen, K. F., Linnemann, A. R., Gezgin, Y., Hell, K., J. R. Nout, M., Smid, E. J., Tamo, M., van Boekel, M. A. J. S., Hoof, J. B. & Frisvad, J. C., 2016, In : P L o S One. 11, 10, 14 p., e0164310.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
256 Downloads (Pure)

Effect of secretory pathway gene overexpression on secretion of a fluorescent reporter protein in Aspergillus nidulans

Schalén, M., Anyaogu, D. C., Hoof, J. B. & Workman, M., 2016, In : Fungal Biology and Biotechnology. 3, 1, 14 p., 3.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
352 Downloads (Pure)

Linker Flexibility Facilitates Module Exchange in Fungal Hybrid PKS-NRPS Engineering

Nielsen, M. L., Petersen, T. I., Petersen, L. M., Mortensen, U. H., Andersen, M. R., Hoof, J. B. & Larsen, T. O., 2016, In : P L o S One. 11, 8, 18 p., e0161199.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
295 Downloads (Pure)

Rapid detection and identification of Stachybotrys and Chaetomium species using tissue PCR analysis

Lewinska, A. M., Peuhkuri, R. H., Rode, C., Andersen, B. & Hoof, J. B., 2016, In : Journal of Microbiological Methods. 130, p. 115-122 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Visualization of the structural changes in plywood and gypsum board during the growth of Chaetomium globosum and Stachybotrys chartarum

Lewinska, A. M., Hoof, J. B., Peuhkuri, R. H., Rode, C., Lilje, O., Foley, M., Trimby, P. & Andersen, B., 2016, In : Journal of Microbiological Methods. 129, p. 28-38 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2015

A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi

Nødvig, C. S., Nielsen, J. B., Kogle, M. E. & Mortensen, U. H., 2015, In : P L o S One. 10, 7, 18 p., e0133085.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
391 Downloads (Pure)

Combining Stable Isotope Labeling and Molecular Networking for Biosynthetic Pathway Characterization

Klitgaard, A., Nielsen, J. B., Frandsen, R. J. N., Andersen, M. R. & Nielsen, K. F., 2015, In : Analytical Chemistry. 87, 13, p. 6520-6526 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2013

Accurate prediction of secondary metabolite gene clusters in filamentous fungi.

Andersen, M. R., Nielsen, J. B., Klitgaard, A., Petersen, L. M., Zachariasen, M., Hansen, T. J., Holberg Blicher, L., Gotfredsen, C. H., Larsen, T. O., Nielsen, K. F. & Mortensen, U. H., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. E99-E107

Research output: Contribution to journalJournal articleResearchpeer-review

Aspergillus nidulans Synthesize Insect Juvenile Hormones upon Expression of a Heterologous Regulatory Protein and in Response to Grazing by Drosophila melanogaster Larvae.

Nielsen, M. T., Klejnstrup, M. L., Rohlfs, M., Anyaogu, D. C., Nielsen, J. B., Gotfredsen, C. H., Andersen, M. R., Hansen, B. G., Mortensen, U. H. & Larsen, T. O., 2013, In : PloS one.. 8, 8, 11 p., e73369.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
415 Downloads (Pure)

Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach

Nielsen, M. T., Nielsen, J. B., Anyaogu, D. C., Holm, D. K., Nielsen, K. F., Larsen, T. O. & Mortensen, U. H., 2013, In : P L o S One. 8, 8, e72871.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
310 Downloads (Pure)

Supercluster takes a walk on the wild side

Nielsen, J. B., Andersen, M. R. & Mortensen, U. H., 2013, In : Trends in Microbiology. 21, 12, p. 617-618

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Adaptive evolution of drug targets in producer and non-producer organisms

Hansen, B. G., Sun, X. E., Genee, H. J., Kaas, C. S., Nielsen, J. B., Frisvad, J. C. & Hedstrom, L., 2012, In : Biochemical Journal. 441, 1, p. 219-226

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
526 Downloads (Pure)

Genetics of Polyketide Metabolism in Aspergillus nidulans

Klejnstrup, M. L., Frandsen, R. J. N., Holm, D. K., Nielsen, M. T., Mortensen, U. H., Larsen, T. O. & Nielsen, J. B., 2012, In : Metabolites. 2, 1, p. 100-133

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
442 Downloads (Pure)

Involvement of a Natural Fusion of a Cytochrome P450 and a Hydrolase in Mycophenolic Acid Biosynthesis

Hansen, B. G., Mnich, E., Nielsen, K. F., Nielsen, J. B., Nielsen, M. T., Mortensen, U. H., Larsen, T. O. & Patil, K. R., 2012, In : Applied and Environmental Microbiology. 78, 14, p. 4908-4913

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
466 Downloads (Pure)
2011

A genome-wide polyketide synthase deletion library uncovers novel genetic links to polyketides and meroterpenoids in Aspergillus nidulans

Nielsen, M. L., Nielsen, J. B., Rank, C., Klejnstrup, M. L., Holm, D. K., Brogaard, K. H., Hansen, B. G., Frisvad, J. C., Larsen, T. O. & Mortensen, U. H., 2011, In : F E M S Microbiology Letters. 321, 2, p. 157-166

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi

Hansen, B. G., Genee, H. J., Kaas, C. S., Nielsen, J. B., Regueira, T. B. H., Mortensen, U. H., Frisvad, J. C. & Patil, K. R., 2011, In : B M C Microbiology. 11, 1, p. 202

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
212 Downloads (Pure)

Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88

Andersen, M. R., Salazar, M. P., Schaap, P. J., van de Vondervoort, P. J. I., Culley, D., Thykær, J., Frisvad, J. C., Nielsen, K. F., Albang, R., Albermann, K., Berka, R. M., Braus, G. H., Braus-Stromeyer, S. A., Corrochano, L. M., Dai, Z., van Dijck, P. W. M., Hofmann, G., Lasure, L. L., Magnuson, J. K., Menke, H. & 27 others, Meijer, M., Meijer, S. L., Nielsen, J. B., Nielsen, M. L., van Ooyen, A. J. J., Pel, H. J., Poulsen, L., Samson, R. A., Stam, H., Tsang, A., van den Brink, J. M., Atkins, A., Aerts, A., Shapiro, H., Pangilinan, J., Salamov, A., Lou, Y., Lindquist, E., Lucas, S., Grimwood, J., Grigoriev, I. V., Kubicek, C. P., Martinez, D., van Peij, N. N. M. E., Roubos, J. A., Nielsen, J. & Baker, S. E., 2011, In : Genome Research. 21, 6, p. 885-897

Research output: Contribution to journalJournal articleResearchpeer-review

2 Downloads (Pure)

Versatile Enzyme Expression and Characterization System for Aspergillus nidulans, with the Penicillium brevicompactum Polyketide Synthase Gene from the Mycophenolic Acid Gene Cluster as a Test Case

Hansen, B. G., Salomonsen, B., Nielsen, M. T., Nielsen, J. B., Hansen, N. B., Nielsen, K. F., Regueira, T. U. B., Nielsen, J., Patil, K. R. & Mortensen, U. H., 2011, In : Applied and Environmental Microbiology. 77, 9, p. 3044-3051

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)
2008

Transient disruption of non-homologous end-joining facilitates targeted genome manipulations in the filamentous fungus Aspergillus nidulans

Nielsen, J. B., Nielsen, M. L. & Mortensen, U. H., 2008, In : Fungal Genetics and Biology. 45, 3, p. 165-170

Research output: Contribution to journalJournal articleResearchpeer-review

2006

Efficient PCR-based gene targeting with a recyclable marker for Aspergillus nidulans

Nielsen, M. L., Lettier, G., Nielsen, J. B. & Mortensen, U. H., 2006, In : Fungal Genetics and Biology. 43, 1, p. 54-64

Research output: Contribution to journalJournal articleResearchpeer-review