• Kemitorvet, 220, 408F

    2800 Kgs. Lyngby

    Denmark

20032022
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Research Output 2003 2020

2020
6 Downloads (Pure)

A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acids

Marella, E. R., Dahlin, J., Dam, M. I., ter Horst, J., Christensen, H. B., Sudarsan, S., Wang, G., Holkenbrink, C. & Borodina, I., 2020, (Accepted/In press) In : Metabolic Engineering.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
4 Downloads (Pure)
Open Access
File
2019
137 Downloads (Pure)

CRISPR/Cas9-RNAi system for combinatorial metabolic engineering of Saccharomyces cerevisiae

Kildegaard, K. R., Ribeiro Ramos Tramontin, L., Chekina, K., Li, M., Goedecke, T. J., Kristensen, M. & Borodina, I., 2019, In : Yeast. 36, 5, p. 237-247

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
52 Downloads (Pure)
Open Access
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27 Downloads (Pure)

Engineering Oleaginous Yeast as the Host for Fermentative Succinic Acid Production From Glucose

Babaei, M., Kildegaard, K. R., Niaei, A., Hosseini, M., Ebrahimi, S., Sudarsan, S., Angelidaki, I. & Borodina, I., 2019, In : Frontiers in Bioengineering and Biotechnology. 7, 14 p., 361.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
48 Downloads (Pure)
Open Access
File
6 Downloads (Pure)

Enhancement of astaxanthin biosynthesis in oleaginous yeast Yarrowia lipolytica via microalgal pathway

Tramontin, L. R. R., Kildegaard, K. R., Sudarsan, S. & Borodina, I., 2019, In : Microorganisms. 7, 10, 17 p., 472.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
12 Downloads (Pure)

Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis

Tiukova, I. A., Møller-Hansen, I., Belew, Z. M., Darbani, B., Boles, E., Nour-Eldin, H. H., Linder, T., Nielsen, J. & Borodina, I., 2019, In : FEMS Microbiology Letters. 366, 17, fnz222.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
5 Downloads (Pure)

Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose

Manuel Borja Zamfir, G., Rodriguez Prado, E. A., Campbell, K., Borodina, I., Chen, Y. & Nielsen, J., 2019, In : Microbial Cell Factories. 18, 1, 14 p., 191.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
14 Downloads (Pure)

Multi-omics analysis of fatty alcohol production in engineered yeasts saccharomyces cerevisiae and yarrowia lipolytica

Dahlin, J., Holkenbrink, C., Marella, E. R., Wang, G., Liebal, U., Lieven, C., Weber, D., McCloskey, D., Ebert, B. E., Herrgård, M. J., Blank, L. M. & Borodina, I., 2019, In : Frontiers in Genetics. 10, 747.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
31 Downloads (Pure)

The transcriptome and flux profiling of Crabtree-negative hydroxy acid producing strains of Saccharomyces cerevisiae reveals changes in the central carbon metabolism

Jessop-Fabre, M. M., Dahlin, J., Biron, M. B., Stovicek, V., Ebert, B. E., Blank, L. M., Budin, I., Keasling, J. D. & Borodina, I., 2019, In : Biotechnology Journal. 14, 9, 11 p., e1900013.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
251 Downloads (Pure)

Understanding metabolite transport gives an upper hand in strain development

Borodina, I., 2019, In : Microbial Biotechnology. 12, 1, p. 69-70

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
2018

Advances in synthetic biology of oleaginous yeast Yarrowia lipolytica for producing non-native chemicals

Darvishi, F., Ariana, M., Marella, E. R. & Borodina, I., 2018, In : Applied Microbiology and Biotechnology. 102, 14, p. 5925-5938

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
330 Downloads (Pure)

EasyCloneYALI: CRISPR/Cas9-based synthetic toolbox for engineering of the yeast Yarrowia lipolytica

Holkenbrink, C., Dam, M. I., Kildegaard, K. R., Beder, J., Dahlin, J., Belda, D. D. & Borodina, I., 2018, In : Biotechnology Journal. 13, 9, 23 p., 1700543.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
219 Downloads (Pure)

Energetic evolution of cellular Transportomes

Darbani, B., Kell, D. B. & Borodina, I., 2018, In : B M C Genomics. 19, 11 p., 418.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
184 Downloads (Pure)

Glucose-dependent promoters for dynamic regulation of metabolic pathways

Maury, J., Kannan, S., Jensen, N. B., Öberg, F. K., Kildegaard, K. R., Forster, J., Nielsen, J., Workman, C. T. & Borodina, I., 2018, In : Frontiers in Bioengineering and Biotechnology. 6, 63.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
89 Downloads (Pure)

Method for production of moth pheromones in yeast

Borodina, I., Holkenbrink, C., Dam, M. I., Löfstedt, C., Ding, B. & Wang, H., 2018, IPC No. C07K14/435; C12N1/16; C12P7/04; C12P7/24; C12P7/64, Patent No. US2018162916 , 14 Jun 2018, Priority date 26 Jun 2015, Priority No. EP20150174099

Research output: Patent

Open Access
File
83 Downloads (Pure)

Methods for producing fatty alcohols and derivatives thereof in yeast

Borodina, I., Holkenbrink, C., Dam, M. I. & Löfstedt, C., 2018, IPC No. C12N9/02; C12P7/04, Patent No. WO2018109163 , 21 Jun 2018, Priority date 16 Dec 2016, Priority No. EP20160204769

Research output: Patent

Open Access
File
253 Downloads (Pure)

Native chinese hamster ovary cell secretion signal peptides for production of recombinant polypeptides

Andersen, M. R., Borodina, I., Do, D. D. & Lund, A. M., 2018, IPC No. C07K14/47; C12N15/85, Patent No. EP3323826 , 23 May 2018, Priority date 21 Nov 2016, Priority No. EP20160199726

Research output: Patent

Open Access
File
125 Downloads (Pure)

Production of desaturated fatty alcohols and desaturated fatty acyl acetates in yeast

Borodina, I., Holkenbrink, C., Dam, M. I., Löfstedt, C., Ding, B. & Wang, H., 2018, IPC No. C12N9/02; C12P7/04, Patent No. WO2018109167 , 21 Jun 2018, Priority date 16 Dec 2016, Priority No. EP20160204783

Research output: Patent

Open Access
File
134 Downloads (Pure)

Yeast cell factories for more sustainable pest control in agriculture/ Engineered Oleaginous Yeast Cell Factories for Fine Chemicals

Borodina, I., 2018, The Danish Microbiological Society Annual Congress 2018 - programme & abstracts. Copenhagen, Denmark: Danish Microbiological Society, p. 13-13

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
2017
67 Downloads (Pure)

BIOREFINE-2G — Result In Brief: Novel biopolymers from biorefinery waste-streams

Stovicek, V., Chen, X., Borodina, I. & Förster, J., 2017, European Commission. 2 p.

Research output: Book/ReportReportCommunication

Open Access
File
255 Downloads (Pure)

Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains

Rodriguez, A., Chen, Y., Khoomrung, S., Özdemir, E., Borodina, I. & Nielsen, J., 2017, In : Metabolic Engineering. 44, p. 265-272

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
1971 Downloads (Pure)

CRISPR/Cas system for yeast genome engineering: advances and applications

Stovicek, V., Holkenbrink, C. & Borodina, I., 2017, In : F E M S Yeast Research. 17, 5, 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Easyclone-markerfree: A vector toolkit for marker-less integration of genes into saccharomyces cerevisiae via CRISPR-Cas9

Jessop Fabre, M., Jakociunas, T., Stovicek, V., Dai, Z., Jensen, M. K., Keasling, J. & Borodina, I., 2017, Synthetic Biology Conference, SEED 2017: Engineering, Evolution, and Design. American Institute of Chemical Engineers, p. 149-150 2 p.

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

322 Downloads (Pure)

Engineering microbial fatty acid metabolism for biofuels and biochemicals

Marella, E. R., Holkenbrink, C., Siewers, V. & Borodina, I., 2017, In : Current Opinion in Biotechnology. 50, p. 39-46

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
482 Downloads (Pure)

Engineering of Yarrowia lipolytica for production of astaxanthin

Kildegaard, K. R., Adiego Pérez, B., Doménech Belda, D., Khangura, J. K., Holkenbrink, C. & Borodina, I., 2017, In : Synthetic and Systems Biotechnology. 2, 4, p. 287-294

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
353 Downloads (Pure)

Metabolic engineering of yeast for fermentative production of flavonoids

Rodriguez Prado, E. A., Strucko, T., Stahlhut, S. G., Kristensen, M., Svenssen, D. K., Förster, J., Nielsen, J. & Borodina, I., 2017, In : Bioresource Technology. 245, Part B, p. 1645-1654

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
187 Downloads (Pure)

Yeast Cell Factories for Production of Fuels and Chemicals

Borodina, I. & Zhao, Z. K., 2017, In : FEMS Yeast Research. 17, 8, 1 p., fox082.

Research output: Contribution to journalEditorialResearchpeer-review

Open Access
File
2016
140 Downloads (Pure)

A toolbox for accelerating strain engineering of oleaginous yeast Yarrowia lipolytica

Holkenbrink, C., Beder, J., Dam, M. I. & Borodina, I., 2016, Online Proceedings. American Institute of Chemical Engineers, 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
737 Downloads (Pure)

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes into Saccharomyces cerevisiae via CRISPR-Cas9

Fabre, M. M. J., Jakociunas, T., Stovicek, V., Dai, Z., Jensen, M. K., Keasling, J. & Borodina, I., 2016, In : Biotechnology Journal. 11, 8, p. 1110-1117 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
348 Downloads (Pure)

EasyCloneMulti: A Set of Vectors for Simultaneous and Multiple Genomic Integrations in Saccharomyces cerevisiae

Maury, J., Germann, S. M., Jacobsen, S. A., Jensen, N. B., Kildegaard, K. R., Herrgard, M., Schneider, K., Koza, A., Förster, J., Nielsen, J. & Borodina, I., 2016, In : P L o S One. 11, 3, 22 p., e0150394.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
418 Downloads (Pure)

Engineering and systems level analysis of Saccharomyces cerevisiae for production of 3 hydroxypropionic acid via malonyl CoA reductase dependent pathway

Kildegaard, K. R., Jensen, N. B., Schneider, K., Czarnotta, E., Özdemir, E., Klein, T., Maury, J., E. Eber, B., Christensen, H. B., Chen, Y., Kim, I-K., Herrgard, M., Blank, L. M., Förster, J., Nielsen, J. & Borodina, I., 2016, In : Microbial Cell Factories. 15, 53, 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast

Skjødt, M. L., Snoek, T., Kildegaard, K. R., Arsovska, D., Eichenberger, M., Goedecke, T. J., Rajkumar, A. S., Zhang, J., Kristensen, M., Lehka, B., Siedler, S., Borodina, I., Jensen, M. K. & Keasling, J., 2016, In : Nature Chemical Biology. 12, 11, p. 951-958 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

229 Downloads (Pure)

Engineering yeast for high-level production of stilbenoid antioxidants

Li, M., Schneider, K., Kristensen, M., Borodina, I. & Nielsen, J., 2016, In : Scientific Reports. 6, 8 p., 36827.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
856 Downloads (Pure)

Glucose-based microbial production of the hormone melatonin in yeast Saccharomyces cerevisiae

Germann, S. M., Jacobsen, S. A., Schneider, K., Harrison, S. J., Jensen, N. B., Chen, X., Stahlhut, S. G., Borodina, I., Luo, H., Zhu, J., Maury, J. & Förster, J., 2016, In : Biotechnology Journal. 11, 5, p. 717-724 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
302 Downloads (Pure)

Microbial production of the flavonoids garbanzol, resokaempferol and fisetin

Stahlhut, S. G., Siedler, S., Neves, A. R., MAURY, JEROME., Förster, J., Gaspar, P., Borodina, I., Rodriguez Prado, E. A. & Strucko, T., 12 May 2016, IPC No. C07D 311/ 30 A I, Patent No. WO2016071505, 12 May 2016, Priority date 11 Jun 2015, Priority No. EP20150171638

Research output: Patent

Open Access
File
164 Downloads (Pure)

Rational and Evolutionary Engineering of Industrial Saccharomyces Cerevisiae Strains for Production of Chemicals from Xylose-Rich Feedstocks

Stovicek, V., Lis, A. V., Borodina, I. & Förster, J., 2016, Online Proceedings. American Institute of Chemical Engineers, 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File

Yeast cell factories for bio-based chemicals

Borodina, I., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
2015

Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae

Borodina, I. & Li, M., 2015, In : F E M S Yeast Research. 15, 1, 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae

Jakociunas, T., Rajkumar, A. S., Zhang, J., Arsovska, D., Rodriguez Prado, E. A., Jendresen, C. B., Skjødt, M. L., Nielsen, A. T., Borodina, I., Jensen, M. K. & Keasling, J., 2015, In : A C S Synthetic Biology. 4, 11, p. 1226-1234 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

427 Downloads (Pure)

CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae

Ronda, C., Maury, J., Jakociunas, T., Jacobsen, S. A. B., Germann, S. M., Harrison, S. J., Borodina, I., Keasling, J. D., Jensen, M. K. & Nielsen, A. T., 2015, In : Microbial Cell Factories. 14, 97, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
527 Downloads (Pure)

CRISPR–Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains

Stovicek, V., Borodina, I. & Förster, J., 2015, In : Metabolic Engineering Communications. 2, p. 13-22 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
456 Downloads (Pure)

De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

Li, M., Kildegaard, K. R., Chen, Y., Rodriguez Prado, E. A., Borodina, I. & Nielsen, J., 2015, In : Metabolic Engineering. 32, p. 1-11

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Development of a yeast cell factory for production of aromatic compounds: test case flavonoids production

Rodriguez Prado, E. A., Kildegaard, K. R., Li, M., Borodina, I., Stahlhut, S. G., Förster, J. & Nielsen, J., 2015, In : Yeast. 32, S1, p. S127-S127 1 p., PS3-26.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

296 Downloads (Pure)

EasyClone 2.0: expanded toolkit of integrative vectors for stable gene expression in industrial Saccharomyces cerevisiae strains

Stovicek, V., Borja Zamfir, G. M., Förster, J. & Borodina, I., Oct 2015, In : Journal of Industrial Microbiology and Biotechnology. 42, 11, p. 1519-1531 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
468 Downloads (Pure)

Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine

Borodina, I., Kildegaard, K. R., Jensen, N. B., Blicher, T. H., Maury, J., Sherstyk, S., Schneider, K., Lamosa, P., Herrgard, M., Rosenstand, I., Öberg, F., Förster, J. & Nielsen, J., 2015, In : Metabolic Engineering. 27, p. 57-64

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
492 Downloads (Pure)

Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis

Rodriguez Prado, E. A., Kildegaard, K. R., Li, M., Borodina, I. & Nielsen, J., 2015, In : Metabolic Engineering. 31, p. 181-188 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
500 Downloads (Pure)

Highly Active and Specific Tyrosine Ammonia-Lyases from Diverse Origins Enable Enhanced Production of Aromatic Compounds in Bacteria and Saccharomyces cerevisiae

Jendresen, C. B., Stahlhut, S. G., Li, M., Gaspar, P., Siedler, S., Förster, J., Maury, J., Borodina, I. & Nielsen, A. T., 2015, In : Applied and Environmental Microbiology. 81, 13, p. 4458-4476 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Metabolic engineering of Saccharomyces cerevisiae for production of chemicals

Borodina, I., 2015, In : Yeast. 32, S1, p. S246 1 p., PS15-4.

Research output: Contribution to journalConference abstract in journalResearchpeer-review