Publications per year
Publications per year
- 32 results
Search results
-
2024
Action and cooperation in alginate degradation by three enzymes from the human gut bacterium Bacteroides eggerthii DSM 20697
Rønne, M. E., Dybdahl Andersen, C., Teze, D., Beenfeldt Petersen, A., Fredslund, F., Stender, E. G. P., Kirk Chaberski, E., Holck, J., Aachmann, F. L., Welner, D. H. & Svensson, B., 2024, In: Journal of Biological Chemistry. 300, 9, 20 p., 107596.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Downloads (Pure) -
A life cycle assessment of early-stage enzyme manufacturing simulations from sustainable feedstocks
Hobusch, M., Kırtel, O., Meramo, S., Sukumara, S. & Hededam Welner, D., 2024, In: Bioresource Technology. 400, 130653.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile49 Downloads (Pure) -
Chemoenzymatic indican for light-driven denim dyeing
Bidart, G. N., Teze, D., Jansen, C. U., Pasutto, E., Putkaradze, N., Sesay, A. M., Fredslund, F., Lo Leggio, L., Ögmundarson, O., Sukumara, S., Qvortrup, K. & Welner, D. H., 2024, In: Nature Communications. 15, 1, 11 p., 1489.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile48 Downloads (Pure) -
Enzymatic glycosylation of aloesone performed by plant UDP-dependent glycosyltransferases
Putkaradze, N., Dato, L., Kırtel, O., Hansen, J. & Welner, D. H., 2024, In: Glycobiology. 34, 9, cwae050.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Downloads (Pure) -
Glucuronan lyases from family PL7 use a Tyr/Tyr syn β-elimination catalytic mechanism for glucuronan breakdown
Vuillemin, M., Pilgaard, B., Kiehn, E., Fredslund, F., Welner, D. H., Meyer, A. S., Aachmann, F. L. & Wilkens, C., 2024, In: Chemical Communications. 60, 4, p. 440-443 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
-
Photocleavage of indican
Welner, D. H. (Inventor), Costoya, G. N. B. (Inventor), Teze, D. (Inventor), Putkaradze, N. (Inventor), Fredslund, F. (Inventor), Uldahl Jansen, C. (Inventor) & Qvortrup, K. (Inventor), 14 Mar 2024, IPC No. D06P 3/ 00 A I, Patent No. WO2024052526, 9 Sept 2022, Priority date 9 Sept 2022, Priority No. EP20220194865Research output: Patent
Open AccessFile5 Downloads (Pure) -
2023
An improved integrative GFP-based vector for genetic engineering of Parageobacillus thermoglucosidasius facilitates the identification of a key sporulation regulator
Millgaard, M., Bidart, G. N., Pogrebnyakov, I., Nielsen, A. T. & Welner, D. H., 2023, In: AMB Express. 13, 1, 44.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile38 Downloads (Pure) -
Functional characterization of the phosphotransferase system in Parageobacillus thermoglucosidasius
Bidart, G. N., Gharabli, H. & Welner, D. H., 2023, In: Scientific Reports. 13, 11 p., 7131.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile28 Downloads (Pure) -
Identification and functional characterization of novel plant UDP-glycosyltransferase (LbUGT72B10) for the bioremediation of 3,4-dichloroaniline
Della Gala, V. & Welner, D. H., 2023, In: RSC Sustainability. 1, 8, p. 2024-2032 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile16 Downloads (Pure) -
Optimisation Of Parageobacillus Thermoglucosidasius For Climate-Positive Acetone Production
Millgaard, M., Pogrebnyakov, I., Nahuel Bidart Costoya, G., Welner, D. H., Ingemann Jensen, S. & Nielsen, A. T., 2023, The Danish Microbiological Society Annual Congress 2023: Abstract book. The Danish Microbiological Society, p. 66-66 1 p. 64Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review
Open AccessFile73 Downloads (Pure) -
Promiscuous Yet Specific: A Methionine-Aromatic Interaction Drives the Reaction Scope of the Family 1 Glycosyltransferase GmUGT88E3 from Soybean
de Boer, R. M., H. Hvid, D. E., Davail, E., Vaitkus, D., Duus, J. Ø., Welner, D. H. & Teze, D., 2023, In: Biochemistry. 62, p. 3343−3346Research output: Contribution to journal › Journal article › Research › peer-review
-
Regioselective Glycosylation of Polyphenols by Family 1 Glycosyltransferases: Experiments and Simulations
de Boer, R. M., Vaitkus, D., Enemark-Rasmussen, K., Maschmann, S., Teze, D. & Welner, D. H., 2023, In: ACS Omega. 8, 48, p. 46300-46308Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile34 Downloads (Pure) -
Sequence mining yields 18 phloretin C-glycosyltransferases from plants for the efficient biocatalytic synthesis of nothofagin and phloretin-di-C-glycoside
Putkaradze, N., Gala, V. D., Vaitkus, D., Teze, D. & Welner, D. H., 2023, In: Biotechnology Journal. 18, 6, 2200609.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile31 Downloads (Pure) -
The function of UDP-glycosyltransferases in plants and their possible use in crop protection
Gharabli, H., Della Gala, V. & Welner, D. H., 2023, In: Biotechnology Advances. 67, 108182.Research output: Contribution to journal › Review › peer-review
Open AccessFile173 Downloads (Pure) -
Thermostable glycosyltransferase variants
Welner, D. H. (Inventor), Costoya, G. N. B. (Inventor) & Leggio, L. L. (Inventor), 31 Aug 2023, IPC No. C12P 17/ 16 A I, Patent No. WO2023161230, 22 Feb 2022, Priority date 22 Feb 2022, Priority No. EP20220158070Research output: Patent
Open AccessFile40 Downloads (Pure) -
2022
Emerging approaches for biocatalysis supporting a sustainable future: Enzymes wanted, dead or alive
Volke, D. C., Cros, A., Welner, D. H. & Nikel, P. I., 2022, In: Chem Catalysis. 2, 10, p. 2400-2402 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
-
Family 1 glycosyltransferases (GT1, UGTs) are subject to dilution-induced inactivation and low chemo stability toward their own acceptor substrates
Teze, D., Bidart, G. N. & Welner, D. H., 2022, In: Frontiers in Molecular Biosciences. 9, 8 p., 909659.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile80 Downloads (Pure) -
Family 1 Glycosyltransferase UGT706F8 from Zea mays Selectively Catalyzes the Synthesis of Silibinin 7-Ο-β-D-Glucoside
Bidart, G. N., Putkaradze, N., Fredslund, F., Kjeldsen, C., Ruiz, A. G., Duus, J. Ø., Teze, D. & Welner, D. H., 2022, In: ACS Sustainable Chemistry and Engineering. 10, 16, p. 5078-5083 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile52 Downloads (Pure) -
In vivo fluorine biocatalysis: Six enzymes in search of a cell factory
Nikel, P. I., Welner, D. H., Cros, A. & Volke, D. C., 20 Oct 2022, In: Chem Catalysis. 2, 10, p. 2403-2405 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
-
Oligomerization engineering of the fluorinase enzyme leads to an active trimer that supports synthesis of fluorometabolites in vitro
Kittila, T.-R., Calero Valdayo, P. M., Fredslund, F., Lowe, P. T., Tezé, D., Nieto Domínguez, M. J., O'Hagan, D., Nikel, P. I. & Welner, D. H., 2022, In: Microbial Biotechnology. 15, 5, p. 1622-1632 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile124 Downloads (Pure) -
Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis
Del Giudice, R., Putkaradze, N., dos Santos, B. M., Hansen, C. C., Crocoll, C., Motawia, M. S., Fredslund, F., Laursen, T. & Welner, D. H., 2022, In: Plant Journal. 111, 6, p. 1539-1549 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile98 Downloads (Pure) -
2021
Discovery of fungal oligosaccharide-oxidising flavo-enzymes with previously unknown substrates, redox-activity profiles and interplay with LPMOs
Haddad Momeni, M., Fredslund, F., Bissaro, B., Raji, O., Vuong, T. V., Meier, S., Nielsen, T. S., Lombard, V., Guigliarelli, B., Biaso, F., Haon, M., Grisel, S., Henrissat, B. P., Welner, D. H., Master, E. R., Berrin, J.-G. & Abou Hachem, M., 2021, In: Nature Communications. 12, 13 p., 2132.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile200 Downloads (Pure) -
Exploring the in Vitro Operating Window of Glycosyltransferase PtUGT1 from Polygonum tinctorium for a Biocatalytic Route to Indigo Dye
Petermeier, P., Fortuna, C., Hübschmann, K. M., Bidart, G. N., Tørring, T., Teze, D., Welner, D. H. & Kara, S., 28 Jun 2021, In: ACS Sustainable Chemistry and Engineering. 9, 25, p. 8497-8506 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile127 Downloads (Pure) -
Natural product C-glycosyltransferases - a scarcely characterised enzymatic activity with biotechnological potential
Putkaradze, N., Tezé, D., Fredslund, F. & Welner, D. H., 2021, In: Natural Product Reports. 38, p. 432-443Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile349 Downloads (Pure) -
O-/N-/S-specificity in glycosyltransferase catalysis: From mechanistic understanding to engineering
Tezé, D., Coines, J., Fredslund, F., Dubey, K. D., Bidart, G. N., Adams, P. D., Dueber, J. E., Svensson, B., Rovira, C. & Welner, D. H., 2021, In: ACS Catalysis. 11, 3, p. 1810-1815Research output: Contribution to journal › Letter › peer-review
Open AccessFile181 Downloads (Pure) -
2020
Evolution-guided engineering of small-molecule biosensors
Snoek, T., Chaberski, E. K., Ambri, F., Kol, S., Bjørn, S. P., Pang, B., Barajas, J. F., Welner, D. H., Jensen, M. K. & Keasling, J. D., 2020, In: Nucleic Acids Research. 48, 1, e3.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile242 Downloads (Pure) -
The catalytic acid-base in GH109 resides in a conserved GGHGG loop and allows for comparable α-retaining and β-inverting activity in an N-acetylgalactosaminidase from Akkermansia muciniphila
Teze, D., Shuoker, B., Chaberski, E. K., Kunstmann, S., Fredslund, F., Nielsen, T. S., Stender, E. G. P., Peters, G. H. J., Nordberg Karlsson, E., Welner, D. H. & Abou Hachem, M., 2020, In: A C S Catalysis. 10, p. 3809-3819 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile716 Downloads (Pure) -
2019
A carbohydrate-binding family 48 module enables feruloyl esterase action on polymeric arabinoxylan
Holck, J., Fredslund, F., Møller, M. S., Brask, J., Krogh, K. B. R. M., Lange, L., Welner, D. H., Svensson, B., Meyer, A. S. & Wilkens, C., 2019, In: Journal of Biological Chemistry. 294, 46, p. 17339-17353 16 p., jbc.RA119.009523.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile414 Downloads (Pure) -
Molecular characteristics of plant UDP-arabinopyranose mutases
Saqib, A., Scheller, H. V., Fredslund, F. & Welner, D. H., 2019, In: Glycobiology. 29, 12, p. 839-846Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile75 Downloads (Pure) -
Structural and functional aspects of mannuronic acid-specific PL6 alginate lyase from the human gut microbe Bacteroides cellulosilyticus
Stender, E. G. P., Andersen, C. D., Fredslund, F., Holck, J., Solberg, A., Teze, D., Peters, G. H. J., Christensen, B. E., Aachmann, F. L., Welner, D. H. & Svensson, B., 2019, In: Journal of Biological Chemistry. 294, 47, p. 17915-17930 17 p., jbc.RA119.010206.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile364 Downloads (Pure) -
2017
Plant cell wall glycosyltransferases: High-throughput recombinant expression screening and general requirements for these challenging enzymes
Welner, D. H., Shin, D., Tomaleri, G. P., DeGiovanni, A. M., Tsai, A.Y.-L., Tran, H. M., Hansen, S. F., Green, D. T., Scheller, H. V., Adams, P. D. & Hofmann, A. (Editor), 2017, In: P L o S One. 12, 6, 20 p., 0177591.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile471 Downloads (Pure) -
X-ray diffraction analysis and in vitro characterization of the UAM2 protein from Oryza sativa
Welner, D. H., Tsai, A. Y.-L., DeGiovanni, A. M., Scheller, H. V. & Adams, P. D., 2017, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications. 73, p. 241-245Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile452 Downloads (Pure)