Personal profile
Profile
My research is centered on lipid-protein interactions. In particular how the hydrophobic coupling between transmembrane proteins and their host bilayer may regulate protein function through changes in the bilayer mechanical properties. Also how membrane mechanical properties affect overall membrane dynamics (e.g. vesiculation). The technological goal of my research is to create biomimetic membranes for biosensor and separation (filtering) applications. Our techniques are electrophysiology, fluorescence-, electron paramagnetic-, and Raman spectroscopy, as well as molecular dynamics and continuum modeling.
Other information
- Member of the Nano-Science Comittee, Universty of Copenhagen 2002.
- Member of Biophysical Society from 1998.
- Referee for Biophysical Journal. External Examiner for Higher Educations in Physics (medlem af censorkorpset i Fysik).
- Postdoctoral grant from the Carlsberg Foundation 2000-2003.
- Postdoctoral grant from the Norman and Rosita Winston Fund 1996-1998.
- Postdoctoral grant from the Danish Reseach Council 1994-1994.
International Experience:
1995-1999 Postdoctoral Fellow, Cornell University Medical College, New York, USA.
Language Skills:
English
Education/Academic qualification
Teaching Diploma (adjunktpædagogikum), University of Copenhagen
2002
PhD, Technical University of Denmark
1990 → 1993
Master of Engineering, Technical University of Denmark
1983 → 1990
High School, Lemvig Gymnasium
1980 → 1983
External positions
Research Director, AQUAporin ApS
2007 → …
Associate Professor, Technical University of Denmark
2003 → …
Assistant Professor, University of Copenhagen
2000 → 2003
Postdoctoral Fellow, Cornell University
1995 → 1999
Postdoctoral Fellow, University of Copenhagen
1994 → 1995
Research Assistant, Royal Veternary and Agricultural University
1993 → 1994
Keywords
- User defined:
- Lipid-protein interactions
- Biomimetic membranes
- Membrane transport
- Membrane channel proteins
- Electrophysiology
- Spectroscopy
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 6 Clean Water and Sanitation -
SDG 7 Affordable and Clean Energy -
SDG 8 Decent Work and Economic Growth -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 11 Sustainable Cities and Communities -
SDG 12 Responsible Consumption and Production -
SDG 13 Climate Action
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Collaborations and top research areas from the last five years
Publications
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Measuring the Gibbs free energy of mixing using the concept of an osmotic engine
Nielsen, D. W. & Helix-Nielsen, C., 2026, In: Physical Chemistry Chemical Physics. 28, 18, p. 11465-11477 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Downloads (Orbit) -
Techno-economic evaluation of water reuse via reverse osmosis for green hydrogen production: A Scandinavian case study
Zhao, D., Kayiran, S., Jiang, T., Vogel, J., Hélix-Nielsen, C. & Zhang, W., 2026, In: Journal of Membrane Science. 749, 13 p., 125424.Research output: Contribution to journal › Journal article › Research › peer-review
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Advanced Catalysts for the Chemical Recycling of Plastic Waste
Qin, J., Wu, F., Dou, Y., Zhao, D., Hélix-Nielsen, C. & Zhang, W., 2025, In: Advanced Materials. 37, 23, 17 p., 2418138.Research output: Contribution to journal › Review › peer-review
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Advances in carbon nanomembranes for separation: from free-standing films to composite structures
Ambrož, A., Schnieders, A., Hélix-Nielsen, C., Gölzhäuser, A. & Petrinić, I., 2025, In: Nanoscale. 17, 29, p. 17004-17015 12 p.Research output: Contribution to journal › Review › peer-review
Open AccessFile58 Downloads (Orbit) -
Cladosporium species detoxify multiple water micropollutants of emerging concern
Leth, M. L., Tang, K., Sørensen, T., Turella, S., Andersen, A. J., Hélix-Nielsen, C., Frisvad, J. C., Søndergaard, T. E., Andersen, H. R. & Hachem, M. A., 2025, In: Environmental Technology and Innovation. 40, 17 p., 104379.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile36 Downloads (Orbit)
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Nanostructured membrane design for waste-heat powered ultrapure water production for Green Hydrogen Production
Chandrasekar, K. K. (PhD Student), Zhang, W. (Main Supervisor), Hélix-Nielsen, C. (Supervisor), Valverde Pérez, B. (Supervisor) & Singh, S. P. (Supervisor)
01/06/2025 → 14/06/2028
Project: PhD
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Sustainable Industrial Laundry Wastewater Treatment by Advanced Membrane Technologies
Zhang, W. (PI), Hartmann, N. B. (CoI), Baun, A. (CoI), Hélix-Nielsen, C. (CoI), Andersen, H. R. (CoI), Damgaard, A. (Project Participant) & Zhao, D. (Project Participant)
01/05/2023 → 30/04/2027
Project: Research
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Enzyme-Immobilized Electrospun Nanofiber Designs and Their Applications in Wastewater Treatment
Zhao, D. (PhD Student), Lipnizki, F. (Examiner), Wu, J. (Examiner), Zhang, W. (Main Supervisor), Hachem, M. A. (Supervisor) & Hélix-Nielsen, C. (Supervisor)
01/12/2019 → 14/06/2023
Project: PhD
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Development of Aquaporin Inside (TM) technology for osmotic membrane bioreactors
Sanahuja Embuena, V. (PhD Student), Hélix-Nielsen, C. (Main Supervisor), Camilleri Rumbau, M. S. (Supervisor), Zhang, W. (Examiner), Christensen, M. L. (Examiner), Petrinic, I. (Examiner) & Andersen, M. F. (Supervisor)
01/06/2018 → 18/11/2021
Project: PhD
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Development op the next generation op Aquaporin Inside TM biomimetic membranes
Górecki, R. P. (PhD Student), Hélix-Nielsen, C. (Main Supervisor), Trzaskus, K. W. (Supervisor), Zhang, W. (Examiner), Christensen, M. L. (Examiner) & Kleinschmidt, J. H. (Examiner)
01/07/2017 → 15/12/2020
Project: PhD