20112020

Research output per year

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Research Output

2019

Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST

Tong, Y., Whitford, C. M., Robertsen, H. L., Blin, K., Jørgensen, T. S., Klitgaard, A. K., Gren, T., Jiang, X., Weber, T. & Lee, S. Y., 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 41, p. 20366-20375

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
57 Downloads (Pure)
2016

An Integrated Metabolomic and Genomic Mining Workflow to Uncover the Biosynthetic Potential of Bacteria

Månsson, M., Vynne, N. G., Klitgaard, A., Rasmussen, J. L. N., Melchiorsen, J., D. Nguyen, D., Sanchez, L. M., Ziemert, N., Dorrestein, P. C., Andersen, M. R. & Gram, L., 2016, In : mSystems. 1, 3, 14 p., e00028-15.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
287 Downloads (Pure)

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Wang, M., Carver, J. J., Pevzner, P., Mohiman, H., Bandeira, N., Phelan, V. V., Sanchez, L. M., Garg, N., Watrous, J., Luzzatto-Knaa, T., Frydenlund Michelsen, C., Jelsbak, L., Månsson, M., Klitgaard, A. & Nielsen, K. F., 2016, In : Nature Biotechnology. 34, 8, p. 828-837 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
346 Downloads (Pure)
2015

Combining Stable Isotope Labeling and Molecular Networking for Biosynthetic Pathway Characterization

Klitgaard, A., Nielsen, J. B., Frandsen, R. J. N., Andersen, M. R. & Nielsen, K. F., 2015, In : Analytical Chemistry. 87, 13, p. 6520-6526 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Combining UHPLC-High Resolution MS and Feeding of Stable Isotope Labeled Polyketide Intermediates for Linking Precursors to End Products

Klitgaard, A., Frandsen, R. J. N., Holm, D. K., Knudsen, P. B., Frisvad, J. C. & Nielsen, K. F., 2015, In : Journal of Natural Products. 78, 7, p. 1518-1525 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)
3997 Downloads (Pure)
2014

Accurate Dereplication of Bioactive Secondary Metabolites from Marine-Derived Fungi by UHPLC-DAD-QTOFMS and a MS/HRMS Library

Kildgaard, S., Mansson, M., Dosen, I., Klitgaard, A., Frisvad, J. C., Larsen, T. O. & Nielsen, K. F., 2014, In : Marine Drugs. 12, p. 3681-3705

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
353 Downloads (Pure)

Aggressive dereplication using UHPLC–DAD–QTOF: screening extracts for up to 3000 fungal secondary metabolites

Klitgaard, A., Iversen, A., Andersen, M. R., Larsen, T. O., Frisvad, J. C. & Nielsen, K. F., 2014, In : Analytical and Bioanalytical Chemistry. 406, 7, p. 1933-1943

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
443 Downloads (Pure)

Comparative Genomic and Metabolomic Analysis of Twelve Strains of Pseudoalteromonas luteoviolacea

Månsson, M., Vynne, N. G., Klitgaard, A., Melchiorsen, J., Dorrestein, P. C. & Gram, L., 2014.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
193 Downloads (Pure)

Molecular and Chemical Characterization of the Biosynthesis of the 6-MSA-Derived Meroterpenoid Yanuthone D in Aspergillus niger.

Holm, D. K., Petersen, L. M., Klitgaard, A., Knudsen, P. B., Jarczynska, Z. D., Nielsen, K. F., Gotfredsen, C. H., Larsen, T. O. & Mortensen, U. H., 2014, In : Chemistry & Biology. 21, 4, p. 519-529 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
561 Downloads (Pure)
2013

Accurate prediction of secondary metabolite gene clusters in filamentous fungi.

Andersen, M. R., Nielsen, J. B., Klitgaard, A., Petersen, L. M., Zachariasen, M., Hansen, T. J., Holberg Blicher, L., Gotfredsen, C. H., Larsen, T. O., Nielsen, K. F. & Mortensen, U. H., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. E99-E107

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Chemical analysis of a genome wide polyketide synthase gene deletion library in Aspergillus nidulans

Larsen, T. O., Klejnstrup, M. L., Nielsen, J. B., Holm, D. K., Petersen, L. M., Klitgaard, A., Nielsen, K. F., Andersen, M. R. & Mortensen, U. H., 2012.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

File
106 Downloads (Pure)

Elucidation of the biosynthesis of meroterpenoid yanuthone D in Aspergillus Niger

Holm, D. K., Petersen, L. M., Klitgaard, A., Jarczynska, Z. D., Larsen, T. O. & Mortensen, U. H., 2012, In : Planta Medica. 78, 11, p. 1069-1069

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Screening of Aspergillus nidulans metabolites from habitat mimicking media using LC-DAD-TOFMS system

Klitgaard, A., Holm, D. K., Frisvad, J. C. & Nielsen, K. F., 2012, In : Planta Medica. 78, P167

Research output: Contribution to journalConference abstract in journalResearchpeer-review