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Research Output 2014 2019

2019

BiP Inducer X: An ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture

Kwang Ha, T., Hansen, A. H., Kildegaard, H. F. & Min Lee, G., 2019, In : Biotechnology Journal. e1900130.

Research output: Contribution to journalJournal articleResearchpeer-review

2 Downloads (Pure)
Open Access
File
10 Downloads (Pure)

Glycosylation of proteins

Voldborg, B., Kol, S., Hansen, A. & Kildegaard, H., 6 Jun 2019, IPC No. C12P 21/ 02 A I, Patent No. WO2019105770, 28 Nov 2017, Priority date 11 Jul 2018, Priority No. EP20180182948

Research output: Patent

Open Access
File
2018
220 Downloads (Pure)

Baicalein reduces oxidative stress in CHO cell cultures and improves recombinant antibody productivity

Kwang Ha, T., Hansen, A. H., Kol, S., Kildegaard, H. F. & Min Lee, G., 2018, In : Biotechnology Journal. 13, 3, 10 p., 1700425.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
54 Downloads (Pure)

CRISPR/Cas9-multiplexed editing of Chinese hamster ovary B4Gal-T1, 2, 3 and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins

Amann, T., Hansen, A. H., Kol, S., Min Lee, G., Andersen, M. R. & Kildegaard, H. F., 2018, In : Biotechnology Journal. 13, 10, 9 p., 1800111 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

The cellular impact of glycoengineering

Lewis, N. E., Chiang, A. W. T., Bao, B., Kuo, C., Kellman, B., Richelle, A., Liang, A., Arnsdorf, J., Sukhova, Z., Ménard, P., Hansen, A. H., Yang, Z., Joshi, H., Clausen, H. & Voldborg, B. G., 2018, In : Glycobiology. 28, 12, p. 1074-1074

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
2017

Building a fructan LC–MS2 library and its application to reveal the fine structure of cereal grain fructans

Verspreet, J., Hansen, A. H., Harrison, S. J., Vergauwen, R., Van den Ende, W. & Courtin, C. M., 2017, In : Carbohydrate Polymers. 174, p. 343-351

Research output: Contribution to journalJournal articleResearchpeer-review

213 Downloads (Pure)

CHO glyco-engineering using CRISPR/Cas9 multiplexing for protein production with homogeneous N-glycan profiles

Amann, T., Hansen, A. H., Pristovsek, N., Singh, A., Min Lee, G., Andersen, M. R. & Kildegaard, H. F., 2017. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
1 Downloads (Pure)

De-bugging and maximizing plant cytochrome P450 production in Escherichia coli with C-terminal GFP fusions

Christensen, U., Vazquez Albacete, D., Søgaard, K. M., Hobel, T., Nielsen, M. T., Harrison, S. J., Hansen, A. H., Møller, B. L., Seppala, S. & Nørholm, M., 2017, In : Applied Microbiology and Biotechnology. 101, 10, p. 4103-4113 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

79 Downloads (Pure)

Humanizing recombinant glycoproteins from Chinese hamster ovary cells

Hansen, A. H., Amann, T., Kol, S. & Kildegaard, H. F., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
152 Downloads (Pure)

Predictive glycoengineering of biosimilars using a Markov chain glycosylation model

Spahn, P. N., Hansen, A. H., Kol, S., Voldborg, B. G. & Lewis, N. E., 2017, In : Biotechnology Journal. 12, 2, 10 p., 1600489.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
2016
1 Downloads (Pure)

A Markov chain model for N-linked protein glycosylation – towards a low-parameter tool for model-driven glycoengineering

Spahn, P. N., Hansen, A. H., Hansen, H. G., Arnsdorf, J., Kildegaard, H. F. & Lewis, N., 2016, In : Metabolic Engineering. 33, p. 52-66 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

95 Downloads (Pure)

Method for determining the composition of the sugar moiety of a sugar containing compound

Harrison, S. J. & Hansen, A. H., 12 May 2016, IPC No. G01N 33/ 00 A I, Patent No. WO2016071485, 12 May 2016, Priority date 7 Nov 2014, Priority No. EP20140192270

Research output: Patent

Open Access
File
2015
119 Downloads (Pure)

A novel low-parameter computational model to aid in-silico glycoengineering

Spahn, P. N., Hansen, A. H., Hansen, H. G., Arnsdorf, J., Kildegaard, H. F. & Lewis, N. E., 2015, In : BMC Proceedings. 9, Suppl. 9, 3 p., P26.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
File

LC-MS analysis reveals the presence of graminan- and neo-type fructans in wheat grains

Verspreet, J., Hansen, A. H., Dornez, E., Delcour, J. A., Van den Ende, W., Harrison, S. J. & Courtin, C. M., 2015, In : Journal of Cereal Science. 61, p. 133-138 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

One-step generation of triple knockout CHO cell lines using CRISPR/Cas9 and fluorescent enrichment.

Grav, L. M., Lee, J. S., Thomsen, S. G., Beuchert Kallehauge, T., Hansen, A. H., Kol, S., Min Lee, G., Pedersen, L. E. & Kildegaard, H. F., 2015, In : Biotechnology Journal. 10, 9, p. 1446-1456 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2014

A new high-throughput LC-MS method for the analysis of complex fructan mixtures.

Verspreet, J., Hansen, A. H., Dornez, E., Courtin, C. M. & Harrison, S. J., 2014, In : Analytical and Bioanalytical Chemistry. 406, 19, p. 4785-4788 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2266 Downloads (Pure)

Liquid chromatography/mass spectrometry analysis of branched fructans produced in vitro with C-13-labeled substrates

Verspreet, J., Hansen, A. H., Dornez, E., Delcour, J. A., Harrison, S. J. & Courtin, C. M., 2014, In : Rapid Communications in Mass Spectrometry. 28, 20, p. 2191-2200

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File