1996 …2022

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

A Bistable Switch and Anatomical Site Control Vibrio cholerae Virulence Gene Expression in the Intestine

Nielsen, A. T., Dolganov, N. A., Rasmussen, T., Otto, G., Miller, M. C., Felt, S. A., Torreilles, S. & Schoolnik, G. K., 2010, In : P L o S Pathogens. 6, 9, 23 p., e1001102.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
329 Downloads (Pure)

A Capture-SELEX Strategy for Multiplexed Selection of RNA Aptamers Against Small Molecules

Lauridsen, L. H., Doessing, H. B., Long, K. S. & Nielsen, A. T., 2018, Synthetic Metabolic Pathways. Vol. 1671. p. 291-306 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Accelerating Genome Editing in CHO Cells Using CRISPR Cas9 and CRISPy, a Web-Based Target Finding Tool

Ronda, C., Pedersen, L. E., Hansen, H. G., Beuchert Kallehauge, T., Betenbaugh, M., Nielsen, A. T. & Kildegaard, H. F., 2014, In : Biotechnology and Bioengineering (Print). 111, 8, p. 1604-1616

Research output: Contribution to journalJournal articleResearchpeer-review

1 Downloads (Pure)

A metabolic reconstruction of Lactobacillus reuteri JCM 1112 and analysis of its potential as a cell factory

Kristjansdottir, T., Bosma, E. F., Branco Dos Santos, F., Özdemir, E., Herrgård, M. J., França, L., Ferreira, B., Toftgaard Nielsen, A. & Gudmundsson, S., 2019, In : Microbial Cell Factories. 18, 1, 19 p., 186.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
10 Downloads (Pure)

A process for producing a fermentation product from a lignocellulose-containing material.

Jendresen, C. B. & Nielsen, A. T., 25 Feb 2016, IPC No. C12N 9/ 10 A I, Patent No. WO2016026977, 25 Feb 2016, Priority date 22 Aug 2014, Priority No. EP20140182040

Research output: Patent

Open Access
File
122 Downloads (Pure)

A two-cassette reporter system for assessing target gene translation and target gene product inclusion body formation

Nielsen, A. T., Zutz, A. & Lennen, R., 28 Apr 2016, IPC No. C12N 15/ 09 A I, Patent No. WO2016062819, 28 Apr 2016, Priority date 22 Oct 2014, Priority No. EP20140189892

Research output: Patent

Open Access
File
143 Downloads (Pure)

Bacterial cells with improved tolerance to diacids

Lennen, R., Nielsen, A. T., Herrgard, M., Sommer, M. O. A., Feist, A. & Tharwat Tolba Mohamed, E., 2018, IPC No. C12N1/20; C12P7/44; C12P7/46, Patent No. WO2018091525 , 24 May 2018, Priority date 15 Nov 2016, Priority No. US201662422457P

Research output: Patent

Open Access
File
179 Downloads (Pure)

Bacterial cells with improved tolerance to isobutyric acid

Lennen, R., Nielsen, A. T., Herrgård, M., Sommer, M. O. A., Feist, A. & Mohamed, E. T. T., 16 Nov 2017, IPC No. C12P 7/ 52 A I, Patent No. WO2017194696, 16 Nov 2017, Priority date 9 Jun 2016, Priority No. EP20160173673

Research output: Patent

Bacterial cells with improved tolerance to polyamines

Lennen, R., Nielsen, A. T., Herrgaard, M., Sommer, M. O. A., Feist, A. & Tharwat Tolba Mohamed, E., 15 Jun 2017, IPC No. C12P 13/ 00 A I, Patent No. WO2017097828, 15 Jun 2017, Priority date 9 Feb 2016, Priority No. EP20160154829

Research output: Patent

Open Access
File
98 Downloads (Pure)

Bacterial cells with improved tolerance to polyols

Lennen, R., Nielsen, A. T., Herrgard, M., Sommer, M. O. A., Feist, A. & Tharwat Tolba Mohamed, E., 17 Jun 2017, IPC No. C12P7/18 , Patent No. WO2017211883, 14 Dec 2017, Priority date 27 Jun 2016, Priority No. EP20160176365

Research output: Patent

Open Access
File
331 Downloads (Pure)

Bacterial Genome Editing Strategy for Control of Transcription and Protein Stability

Lauritsen, I., Martinez, V., Ronda, C., Nielsen, A. T. & Nørholm, M. H. H., 2018, Synthetic Metabolic Pathways. Vol. 1671. p. 27-37 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Biological processes for the production of aryl sulfates.

Jendresen, C. B. & Nielsen, A. T., 25 Feb 2016, IPC No. C12N 9/ 10 A I, Patent No. WO2016026976, 25 Feb 2016, Priority date 22 Aug 2014, Priority No. EP20140182032

Research output: Patent

Open Access
File
111 Downloads (Pure)

CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae

Jakociunas, T., Rajkumar, A. S., Zhang, J., Arsovska, D., Rodriguez Prado, E. A., Jendresen, C. B., Skjødt, M. L., Nielsen, A. T., Borodina, I., Jensen, M. K. & Keasling, J., 2015, In : A C S Synthetic Biology. 4, 11, p. 1226-1234 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Characterization of a Feedback-Resistant Mevalonate Kinase from the Archaeon Methanosarcina mazei

Primak, Y. A., Du, M., Miller, M. C., Wells, D. H., Nielsen, A. T., Weyler, W. & Beck, Z. Q., 2011, In : APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 77, 21, p. 7772-7778 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Comparative study on aptamers as recognition elements for antibiotics in a label-free all-polymer biosensor

Dapra, J., Lauridsen, L. H., Nielsen, A. T. & Rozlosnik, N., 2013, In : Biosensors and Bioelectronics. 43, 1, p. 315-320

Research output: Contribution to journalJournal articleResearchpeer-review

2 Downloads (Pure)

Consortia based production of biochemicals

Ingemann Jensen, S., Sukumara, S., Özdemir, E., Schneider, K., Calero Valdayo, P. M., Li, S., Ronda, C. & Nielsen, A. T., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access

Consortia based production of biochemicals

Ingemann Jensen, S., Sukumara, S., Özdemir, E., Schneider, K., Li, S., Calero Valdayo, P., Ronda, C. & Nielsen, A. T., 2016, Programme & Abstracts. The Danish Microbiological Society Annual Congress 2016. Danish Microbiological Society, p. 84-85

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
165 Downloads (Pure)

CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae

Ronda, C., Maury, J., Jakociunas, T., Jacobsen, S. A. B., Germann, S. M., Harrison, S. J., Borodina, I., Keasling, J. D., Jensen, M. K. & Nielsen, A. T., 2015, In : Microbial Cell Factories. 14, 97, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
427 Downloads (Pure)

CRISPR/Cas9-based genome editing for simultaneous interference with gene expression and protein stability

Martinez, V., Lauritsen, I., Hobel, T., Li, S., Nielsen, A. T. & Nørholm, M., 2017, In : Nucleic Acids Research. 45, 20, 8 p., gkx797.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
177 Downloads (Pure)

CRMAGE: CRISPR Optimized MAGE Recombineering

Ronda, C., Pedersen, L. E., Sommer, M. O. A. & Nielsen, A. T., 2016, In : Scientific Reports. 6, 11 p., 19452.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
475 Downloads (Pure)

Detection of p-coumaric acid from cell supernatant using surface enhanced Raman scattering

Morelli, L., Jendresen, C. B., Zor, K., Rindzevicius, T., Schmidt, M. S., Nielsen, A. T. & Boisen, A., 2017, In : Procedia Technology. 27, p. 190-192 3 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
File
241 Downloads (Pure)

Developing Lactic Acid Bacteria for the conversion of brown macroalgae into green chemicals and fuels

Bosma, E. F. & Nielsen, A. T., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access

Development and Application of Efficient Forward and Reverse Genetic Tools

Baker, J. P., Saez, J., Ingemann Jensen, S., Wiechmann, A., Bengelsdorf, F., Beck, M., Fernandez-Sanchis, E. M., Müller, V., Nielsen, A. T., Dürre, P., Baldauf, M., Simpson, S. & Minton, N. P., 2017, Proceedings of C1net Conference 3. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
95 Downloads (Pure)

Differential expression of small RNAs under chemical stress and fed-batch fermentation in E. coli

Rau, M. H., Nielsen, A. T. & Long, K., 2015, In : B M C Genomics. 16, 1051, 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
284 Downloads (Pure)

Differential expression of small RNAs under chemical stress and fed-batch fermentation in Escherichia coli

Rau, M. H., Bojanovic, K., Nielsen, A. T. & Long, K. S., 2015, Book of Abstracts. DTU's Sustain Conference 2015. Lyngby: Technical University of Denmark, 1 p. B-8

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
55 Downloads (Pure)

Differential Expression Of Small Rnas Under Chemical Stress And Fed-batch Fermentation In Escherichia Coli

Rau, M. H., Bojanovic, K., Nielsen, A. T. & Long, K., 2015, The Danish Microbiological Society Annual Congress 2015: Programme & Abstracts. Copenhagen, p. 75-75

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Distribution of bacterial growth activity in flow-chamber biofilms

Sternberg, C., Christensen, B. B., Johansen, T., Nielsen, A. T., Andersen, J. B., Givskov, M. C. & Molin, S., 1999, In : Applied and Environmental Microbiology. 65, 9, p. 4108-4117

Research output: Contribution to journalJournal articleResearchpeer-review

Editorial overview: Chemical biotechnology: Interdisciplinary concepts for modern biotechnological production of biochemicals and biofuels

Bornscheuer, U. T. & Nielsen, A. T., 2015, In : Current Opinion in Biotechnology. 35, p. 133-134 2 p.

Research output: Contribution to journalEditorialResearchpeer-review

Engineering of High Yield Production of L-serine in Escherichia coli

Mundhada, H., Schneider, K., Christensen, H. B. & Nielsen, A. T., 2016, In : Biotechnology and Bioengineering. 113, 4, p. 807-816 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Enhanced protein and biochemical production using CRISPRi-based growth switches

Li, S., Jendresen, C. B., Grünberger, A., Ronda, C., Ingemann Jensen, S., Noack, S. & Nielsen, A. T., 2016, In : Metabolic Engineering. 38, p. 274-284 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Exploiting the potential of gas fermentation

Redl, S. M. A., Diender, M., Jensen, T. Ø., Sousa, D. Z. & Nielsen, A. T., 2017, In : Industrial Crops and Products. 106, p. 21-30

Research output: Contribution to journalJournal articleResearchpeer-review

Generation of an E. coli platform strain for improved sucrose utilization using adaptive laboratory evolution

Mohamed, E. T. T., Mundhada, H., Landberg, J. M., Cann, I., Mackie, R. I., Nielsen, A. T., Herrgard, M. J. & Feist, A. M., 2019, In : Microbial Cell Factories. 18, 116.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
87 Downloads (Pure)

Genetically modified microorganisms having improved tolerance towards l-serine.

Mundhada, H. & Nielsen, A. T., 4 Aug 2016, IPC No. C12N 15/ 00 A I, Patent No. WO2016120345, 4 Aug 2016, Priority date 27 Jan 2015, Priority No. EP20150152643

Research output: Patent

Open Access
File
135 Downloads (Pure)

Genetic toolbox for controlled expression of functional proteins in Geobacillus spp.

Pogrebnyakov, I., Jendresen, C. B. & Nielsen, A. T., 2017, In : PLOS ONE. 12, 2, 15 p., e0171313.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
482 Downloads (Pure)

Genome editing of lactic acid bacteria: opportunities for food, feed, pharma and biotech

Börner, R. A., Kandasamy, V., Axelsen, A. M., Nielsen, A. T. & Bosma, E. F., 2019, In : F E M S Microbiology Letters. 366, 1, 12 p., fny291.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
363 Downloads (Pure)

Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals

Rau, M. H., Calero Valdayo, P., Lennen, R., Long, K. & Nielsen, A. T., 2016, In : Microbial Cell Factories. 15, 18 p., 176.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
418 Downloads (Pure)

Genome-wide identification of tolerance mechanisms towards p-coumaric acid in Pseudomonas putida

Calero, P., Jensen, S. I., Bojanovič, K., Lennen, R., Koza, A. & Nielsen, A. T., 2018, In : Biotechnology and Bioengineering. 115, 3, p. 762-774

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
358 Downloads (Pure)

Genome-wide systematic identification of methyltransferase recognition and modification patterns

Jensen, T. Ø., Tellgren-Roth, C., Redl, S. M. A., Maury, J., Baallal Jacobsen, S. A., Pedersen, L. E. & Nielsen, A. T., 2019, In : Nature Communications. 10, 1, 3311.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
87 Downloads (Pure)

Highly Active and Specific Tyrosine Ammonia-Lyases from Diverse Origins Enable Enhanced Production of Aromatic Compounds in Bacteria and Saccharomyces cerevisiae

Jendresen, C. B., Stahlhut, S. G., Li, M., Gaspar, P., Siedler, S., Förster, J., Maury, J., Borodina, I. & Nielsen, A. T., 2015, In : Applied and Environmental Microbiology. 81, 13, p. 4458-4476 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
500 Downloads (Pure)

Identification of a novel group of bacteria in sludge from a deteriorated biological phosphorus removal reactor

Nielsen, A. T., Liu, W-T., Filipe, C., Grady, L., Molin, S. & Stahl, D. A., 1999, In : Applied and Environmental Microbiology. 65, 3, p. 1251-1258

Research output: Contribution to journalJournal articleResearchpeer-review

Improved biological processes for the production of aryl sulfates

Jendresen, C. B. & Nielsen, A. T., 31 Aug 2017, IPC No. C12P 5/ 00 A I, Patent No. WO2017144671, 31 Aug 2017, Priority date 24 Feb 2016, Priority No. EP20160157231

Research output: Patent

Open Access
File
108 Downloads (Pure)

Improved process for producing a fermentation product from a lignocellulose-containing material

Jendresen, C. B. & Nielsen, A. T., 31 Aug 2017, IPC No. C12P 11/ 00 A I, Patent No. WO2017144670, 31 Aug 2017, Priority date 24 Feb 2016, Priority No. EP20160157232

Research output: Patent

Open Access
File
349 Downloads (Pure)

Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution

Mundhada, H., Seoane, J. M., Schneider, K., Christensen, H. B., Koza, A., Herrgard, M., Feist, A. & Nielsen, A. T., 2017, In : Metabolic Engineering. 39, p. 141–150 24 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
488 Downloads (Pure)

Increased tolerance towards serine obtained by adaptive laboratory evolution

Mundhada, H., Seoane, J. M., Koza, A., Herrgard, M., Feist, A. & Nielsen, A. T., 2014, Proceedings of SIMB Annual meeting 2014. P57

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
101 Downloads (Pure)

Increasing production yield of tyrosine and mevalonate through inhibition of biomass formation

Li, S., Jendresen, C. B. & Nielsen, A. T., 2016, In : Process Biochemistry. 51, 12, p. 1992–2000 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Industrializing a Bacterial Strain for l -Serine Production through Translation Initiation Optimization

Rennig, M., Mundhada, H., Wordofa, G. G., Gerngross, D., Wulff, T., Worberg, A., Nielsen, A. T. & Nørholm, M. H. H., 2019, In : ACS Synthetic Biology. 8, 10, p. 2347-2358

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
21 Downloads (Pure)

Injection molded lab-on-a-disc platform for screening of genetically modified E. coli using liquid-liquid extraction and surface enhanced Raman scattering

Morelli, L., Serioli, L., Centorbi, F. A., Jendresen, C. B., Matteucci, M., Ilchenko, O., Demarchi, D., Nielsen, A. T., Zor, K. & Boisen, A., 2018, In : Lab on a Chip. 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
102 Downloads (Pure)