Ubiquitin Signalling and Inflammation

  • Postal addressShow on map

    Søltofts Plads, Building 221

    DK-2800 Kgs. Lyngby

    Denmark

Organisation profile

Organisation profile

We aim to understand how inflammation – the body’s first and rapid response to infection or tissue damage – is controlled. We try to understand how this inflammatory response is orchestrated and regulated at the cellular and molecular level by a wealth of cross-talking signalling pathways.

A particular focus in the lab is how the ubiquitin system controls and coordinates the pro-inflammatory signalling. Ubiquitination is the post-translational conjugation of the small protein ubiquitin to substrates. This signalling mechanism regulates virtually all cellular processes and it is particularly critical for initiating and coordinating inflammatory signalling.

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Dive into the research topics where Ubiquitin Signalling and Inflammation is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
View full fingerprint

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Explore network further
View all 6 profiles
  • 6 Contribution to newspaper - Comment/debate
  • 2 Journal article
  • 1 Review

  • Apoptotic cell death in disease—Current understanding of the NCCD 2023

    Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J. & Bazan, N. G. & 208 others, Becker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.

    Research output: Contribution to journal › Review › peer-review

    Open Access
    File
    179 Downloads (Pure)

  • Justitsministeren behandler forskere som politiske modstandere

    Autzen, A. A. A., Vallgårda, K., Pristed, B. B., Kropp, K., Jønsson, A. B. R., Hansen, N. C., Kristensen, P. M., Laustsen-Kiel, A. H., Andersen, P. E., Høyland-Kroghsbo, N. M., Eriksen, J. J., Jensen, L. K., Bjørk, A. A., Damgaard, R. B., Clemmensen, C., Danbolt, M., Sylow, L., Andersen, L. M. & Kristensen, L. B., 2023, In: Uniavisen. 5 p.

    Research output: Contribution to journal › Contribution to newspaper - Comment/debate

    Open Access
    File

  • NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-1 condensation with p62

    Furthmann, N., Angersbach, L., Bader, V., Blusch, A., Goel, S., Sánchez-Vicente, A., Krause, L. J., Grover, P., Trinkhaus, V. A., van Well, E. M., Jaugstetter, M., Tschulik, K., Damgaard, R. B., Saft, C., Ellrichmann , G., Gold, R., Koch, A., Englert, B., Glatzel, M. & Hartl, F. U. & 5 others, Nakamura, K., Christine, C. W., Huang, E. J., Tatzelt, J. & Winklhofer, K. F., 2023, In: Nature Communications. 14, 24 p., 8368.

    Research output: Contribution to journal › Journal article › Research › peer-review

    Open Access
    File
    87 Downloads (Pure)
View all 9 research outputs
View all 5 projects
  • 8 Peer review of manuscripts
View all 8 activities