• Ørsteds Plads, Building 345C

    DK-2800 Kgs. Lyngby

    Denmark

Research Output

2020

Optimization in Detection of Antigen-Specific T Cells Through Differentially Labeled MHC Multimers

Pedersen, N. W., Laske, K., Maurer, D., Welters, M., Walter, S., Gouttefangeas, C. & Hadrup, S. R., 2020, (Accepted/In press) In : Cytometry. Part A.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

CD8+ T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

Pedersen, N. W., Holm, A., Kristensen, N. P., Bjerregaard, A-M., Bentzen, A. K., Marquard, A. M., Tamhane, T., Burgdorf, K. S., Ullum, H., Jennum, P., Knudsen, S., Hadrup, S. R. & Kornum, B. R., 2019, In : Nature Communications. 10, 1, 12 p., 837.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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179 Downloads (Pure)

Characterization of the ocular microbiome - the importance of contaminant filtration when interpreting 16S rRNA gene sequencing outcome

Andersson, J., Vogt, J. K., Holmgaard, K., Dalgaard, M. D. & Heegaard, S., 2019, In : Investigative Ophthalmology & Visual Science. 60, 9, 4695.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Dissecting the T cell receptor interactions governing recognition of peptide-MHC complexes

Bentzen, A. K., Such, L., Jensen, K. K., Marquard, A. M., Jessen, L. E., Miller, N. J., Church, C. D., Lyngaa, R. B., Koelle, D. M., Becker, J. C., Linnemann, C., Schumacher, T. N. M., Marcatili, P., Nghiem, P., Nielsen, M. & Hadrup, S. R., 2019, In : European Journal of Immunology. 49, Suppl. 3 SI, p. 1787-1787 O116.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

Saini, S. K., Tamhane, T., Anjanappa, R., Saikia, A., Ramskov, S., Donia, M., Svane, I. M., Jakobsen, S. N., Garcia-Alai, M., Zacharias, M., Meijers, R., Springer, S. & Hadrup, S. R., 2019, In : Science Immunology. 4, 37, 13 p., eaau9039.

Research output: Contribution to journalJournal articleResearchpeer-review

Global network of computational biology communities: ISCB's Regional Student Groups breaking barriers

Shome, S., Parra, R. G., Fatima, N., Monzon, A. M., Cuypers, B., Moosa, Y., Coimbra, N. D. R., Assis, J., Giner-Delgado, C., Dönertaş, H. M., Cuesta-Astroz, Y., Saarunya, G., Allali, I., Gupta, S., Srivastava, A., Kalsan, M., Valdivia, C., J Olguin-Orellana, G., Papadimitriou, S., Parisi, D. & 22 others, Kristensen, N. P., Rib, L., Guebila, M. B., Bauer, E., Zaffaroni, G., Bekkar, A., Ashano, E., Paladin, L., Necci, M., Moreyra, N. N., Rydén, M., Villalobos-Solís, J., Papadopoulos, N., Rafael, C., Karakulak, T., Kaya, Y., Gladbach, Y., Dhanda, S. K., Šoštarić, N., Alex, A., DeBlasio, D. & Rahman, F., 2019, In : F1000Research. 8, 9 p.

Research output: Contribution to journalEditorialResearch

Open Access
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HLA-C restricted neoepitopes contribute significantly to the immune recognition of cancer

Ramskov, S., Hansen, K. U., Saini, K. S., Sturm, T., Borch, A., Bjerregaard, A-M., Bentzen, K. A., Marquard, M. A., Donia, M., Andersen, R., Draghi, A., Reading, J., Vogler, I., Derhovanessian, E., Lassen, U., Sahin, U., Swanton, A. C., Quezada, S., Svane, I. M., Fugmann, T. & 1 others, Hadrup, R. S., 2019, In : European Journal of Immunology. 49, Suppl. 3 SI, p. 387-387 O066.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Identification of T Cell Antigens for Precision-Targeted Immune Therapy of Cancer

Ramskov, S., 2019, DTU Health Technology. 58 p.

Research output: Book/ReportPh.D. thesis

Open Access
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31 Downloads (Pure)
Open Access
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45 Downloads (Pure)

Large-scale identification and transcriptional characterisation of auto-reactive CD8 T cells in multiple sclerosis

Pedersen, N. W., Kristensen, N. P., Bentzen, A. K., von Essen, M. R., Selleberg, F. T. & Hadrup, S. R., 2019, In : European Journal of Immunology. 49, Suppl. 3 SI, p. 388-389 O068.

Research output: Contribution to journalJournal articleResearchpeer-review

Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides

Moss, K. H., Popova, P., Hadrup, S. R., Astakhova, K. & Taskova, M., 2019, In : Molecular Pharmaceutics. 16, 6, p. 2265-2277 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

220 Downloads (Pure)

Pilot study on the feasibility, safety and immunogenicity of a personalized neoantigen-targeted immunotherapy (NeoPepVac) in combination with anti-PD-1 or anti-PD-L1 in advanced solid tumors

Moerk, S. K., Donia, M., Kringelum, J. V., Bogenrieder, T., Rønø, B., Sorensen, A. B., Draghi, A., Bol, K. F., Petersen, N. V., Kadivar, M., Hernandez, S. S., Hadrup, S. R., Andreasen, L. V., Christensen, D., Andersen, P. L. & Svane, I. M., 2019, In : Annals of Oncology. 30, Supplement_11, 111P.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Prediction of nephrotoxicity associated with cisplatin-based chemotherapy in testicular cancer patients

Garcia, S., Lauritsen, J., Zhang, Z., Dalgaard, M. D., Nielsen, R. L., Daugaard, G. & Gupta, R., 2019, In : European journal of human genetics. 27, Suppl. 2, p. 1686-1686

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Radiotherapy combined with the immunocytokine L19-IL2 alters the systematic and tumor-infiltrating immune compartments

Kadivar, M., Spörri, L., Rekers, N. H., Meldgaard, T. S., Dubois, L., Lambin, P. & Hadrup, S. R., 2019, In : European Journal of Immunology. 49, Suppl. 3, p. 1837-1838 2 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Retinoic Acid Signaling in Stromal Cells Regulates Intestinal Lymphoid Tissue Stromal Cell Development

Von Burg, N. C., Mörbe, U., Nos, G., Sitnik, K. M., Gonzalez-Izarzugaza, J. M., Vandamme, J., Ludewig, B., Svensson Frej, M., Brunak, S. & Agace, W. W., 2019.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

TRACERx Consortium, 2019, In : Nature Medicine. 25, 10, p. 1549-1559 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

T-cell-receptor cross-recognition and strategies to select safe T-cell receptors for clinical translation

Bentzen, A. K. & Hadrup, S. R., 2019, In : Immuno-Oncology Technology . 2, p. 1-10

Research output: Contribution to journalReviewResearchpeer-review

Open Access
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients

Viborg, N., Ramskov, S., Andersen, R. S., Sturm, T., Fugmann, T., Bentzen, A. K., Rafa, V. M., Straten, P. T., Svane, I. M., Met, Ö. & Hadrup, S. R., 2019, In : OncoImmunology. 8, 12, 11 p., e1663107.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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15 Downloads (Pure)

TCR engaging antigen-scaffolds for targeted expansion of functionally improved T cells for adoptive cell therapy

Kladis, G., Mindahl, V. R., Tamhane, T., Bentzen, A. K., Donia, M., Svane, I. M., Niessner, H., Sinnberg, T., Garbe, C., Jakobsen, S. N., Schmees, C. & Hadrup, S. R., 2019, In : Annals of Oncology. 30, Supplement_11, 39P .

Research output: Contribution to journalConference abstract in journalResearchpeer-review

2018

Correction: Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma

Bjoern, J., Lyngaa, R., Andersen, R., Hölmich, L. R., Hadrup, S. R., Donia, M. & Svane, I. M., 2018, In : OncoTarget. 9, 88, p. 35870 1 p.

Research output: Contribution to journalComment/debateCommunication

Open Access
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11 Downloads (Pure)
2015

Determining antigen recognition through barcoding of mhc multimers

Reker Hadrup, S., Pedersen, H., Jakobsen, S. & Bentzen, A. K., 10 Dec 2015, IPC No. G01N 33/ 569 A I, Patent No. WO2015185067, 6 Jun 2014, Priority date 6 Jun 2014, Priority No. DK2014PA70340

Research output: Patent

Open Access
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12 Downloads (Pure)

General detection and isolation of specific cells by binding of labeled molecules

Pedersen, H., Jakobsen, S., Hadrup, S. R., Bentzen, A. K. & Johansen, K. H., 17 Dec 2015, IPC No. G01N 33/ 533 A I, Patent No. WO2015188839, 6 Jan 2015, Priority date 16 Aug 2014, Priority No. DK2014PA00453

Research output: Patent

Open Access
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54 Downloads (Pure)