In order to accelerate rational strain building, the section designs, assembles and characterises synthetic regulatory DNA parts. The section also develops targeted multiplex genome editing tools for one-step biological transformation of cell factories.

To speed-up the selection of the best-performing cell factories, the section also develops biosensors for both small-molecule production and optimal precursor supplies required for bio-based chemical production.

All projects are aimed towards global industrial needs within design, build and screening of new yeast cell factories.

The section's aim is to produce: 

• Small-molecule biosensors for high-throughput screening of cell factories 
• Robust yeast cell factories with optimised precursor supply 
• Targeted multiplex genome editing systems 
• Characterisation of DNA parts and synthetic promoters for industrial fermentation