Publications per year
Publications per year
Organisation profile
Organisation profile
The Synthetic Biology Tools for Yeast section focuses on accelerating rational strain building and current labor-intensive trial and error engineering. Furthermore, the section focuses on providing more tools for high-throughput screening of cell factories.
In order to accelerate rational strain building, the section designs, assembles and characterises synthetic regulatory DNA parts. The section also develops targeted multiplex genome editing tools for one-step biological transformation of cell factories.
To speed-up the selection of the best-performing cell factories, the section also develops biosensors for both small-molecule production and optimal precursor supplies required for bio-based chemical production.
All projects are aimed towards global industrial needs within design, build and screening of new yeast cell factories.
The section's aim is to produce:
- Small-molecule biosensors for high-throughput screening of cell factories
- Robust yeast cell factories with optimised precursor supply
- Targeted multiplex genome editing systems
- Characterisation of DNA parts and synthetic promoters for industrial fermentation
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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A chromosome-scale genome assembly of Rauvolfia tetraphylla facilitates the identification of the complete ajmaline biosynthetic pathway
Lezin, E., Carqueijeiro, I., Cuello, C., Durand, M., Jansen, H. J., Vergès, V., Williams, C. B., Oudin, A., De Bernonville, T. D., Petrignet, J., Celton, N., St-Pierre, B., Papon, N., Sun, C., Dirks, R. P., O'Connor, S. E., Jensen, M. K., Besseau, S. & Courdavault, V., 2024, (Accepted/In press) In: Plant Communications. 100784.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
A molecular toolkit of cross-feeding strains for engineering synthetic yeast communities
Peng, H., Darlington, A. P. S., South, E. J., Chen, H. H., Jiang, W. & Ledesma-Amaro, R., 2024, In: Nature Microbiology. 9, 3, p. 848-863 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Downloads (Pure) -
Can biotechnology lead the way toward a sustainable pharmaceutical industry?
Etit, D., Meramo, S., Ögmundarson, Ó., Jensen, M. K. & Sukumara, S., 2024, In: Current Opinion in Biotechnology. 87, 103100.Research output: Contribution to journal › Review › peer-review
Open AccessFile20 Downloads (Pure)
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Developing new computational graph-based methods for genomics level only and genomic and metabolic data types for natural product discovery
Kronborg Cantalapiedra, C. (PhD Student), Garg, S. (Main Supervisor) & Jensen, E. D. (Supervisor)
01/12/2023 → 30/11/2026
Project: PhD
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Enabling efficient C1 assimilation in Pseudomonasputida through synthetic metabolism
Favoino, G. (PhD Student), Nikel, P. I. (Main Supervisor) & Jensen, M. K. (Supervisor)
01/09/2023 → 31/08/2026
Project: PhD
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Combining enzyme and metabolic engineering for microbial supply of therapeutic phytochemicals
Holtz, M. (PhD Student), Borodina, I. (Supervisor), Acevedo-Rocha, C. G. (Main Supervisor) & Jensen, M. K. (Supervisor)
01/09/2023 → 31/08/2026
Project: PhD
Activities
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Design and Application of S-Adenosylmethionine Methyltransferase Growth-Coupling for Evolutionary Engineering
Hansen, A. S. L. (Speaker)
24 Jun 2019Activity: Talks and presentations › Conference presentations
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A Universal Methyltransferase Growth Coupling System for Evolutionary Enzyme, Pathway and Host Engineering
Hansen, A. S. L. (Other)
24 Jun 2018 → 28 Jun 2018Activity: Other
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EMBO Workshop
Hansen, A. S. L. (Participant)
18 Oct 2018Activity: Attending an event › Participating in or organising a conference
Prizes
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Top Poster Winner - 2018 Student/Young Investigator Poster Award
Hansen, A. S. L. (Recipient), 27 Jun 2018
Prize: Prizes, scholarships, distinctions