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A community-driven reconstruction of the Aspergillus niger metabolic network

Brandl, J., Aguilar-Pontes, M. V., Schäpe, P., Nørregaard, A., Arvas, M., Ram, A. F. J., Meyer, V., Tsang, A., de Vries, R. P. & Andersen, M. R., 2018, In : Fungal Biology and Biotechnology. 5, 16 p., 16.

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A comparative genomics study of 23 Aspergillus species from section Flavi

Kjærbølling, I., Vesth, T. C., Frisvad, J. C., Nybo, J. L., Theobald, S., Kildgaard, S., Petersen, T. I., Kuo, A., Sato, A., Lyhne, E. K., Kogle, M. E., Wiebenga, A., Kun, R. S., Lubbers, R. J. M., Mäkelä, M. R., Barry, K., Chovatia, M., Clum, A., Daum, C., Haridas, S. & 17 others, He, G., LaButti, K., Lipzen, A., Mondo, S., Pangilinan, J., Riley, R., Salamov, A., Simmons, B. A., Magnuson, J. K., Henrissat, B., Mortensen, U. H., Larsen, T. O., de Vries, R. P., Grigoriev, I. V., Machida, M., Baker, S. E. & Andersen, M. R., 2020, In : Nature Communications. 11, 1, 12 p., 1106.

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A critical review of producers of small lactone mycotoxins: patulin, penicillic acid and moniliformin

Frisvad, J. C., 2018, In : World Mycotoxin Journal. 11, 1, p. 73-100

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Acrophiarin (antibiotic S31794/F-1) from Penicillium arenicola shares biosynthetic features with both Aspergillus- and Leotiomycete-type echinocandins

Lan, N., Perlatti, B., Kvitek, D. J., Wiemann, P., Harvey, C. J. B., Frisvad, J. C., An, Z. & Bills, G. F., 2020, In : Environmental Microbiology. 22, 6, p. 2292-2311 20 p.

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Acurin A, a novel hybrid compound, biosynthesized by individually translated PKS- and NRPS-encoding genes in Aspergillus aculeatus

Wolff, P. B., Nielsen, M. L., Slot, J. C., Andersen, L. N., Petersen, L. M., Isbrandt, T., Holm, D. K., Mortensen, U. H., Nødvig, C. S., Larsen, T. O. & Hoof, J. B., 2020, In : Fungal Genetics and Biology. 139, 10 p., 103378.

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A modular metabolic engineering approach for the production of 1,2-propanediol from glycerol by Saccharomyces cerevisiae

Islam, Z-U., Klein, M., Aßkamp, M. R., Ødum, A. S. R. & Nevoigt, E., 2017, In : Metabolic Engineering. 44, p. 223-235

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An Online Compendium of CHO RNA-Seq Data Allows Identification of CHO Cell Line-specific Transcriptomic Signatures

Singh, A., Kildegaard, H. F. & Andersen, M. R., 2018, In : Biotechnology Journal. 13, 10, 11 p., 1800070.

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Anthelmintic and metabolomic analyses of chicory (Cichorium intybus) identify an industrial by-product with potent in vitro antinematodal activity

Pena-Espinoza, M. A., Valente, A. H., Bornancin, L., Simonsen, H. T., Thamsborg, S. M., Williams, A. R. & López-Muñoz, R., 2020, In : Veterinary Parasitology. 280, 11 p., 109088.

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Anthelmintic effects of forage chicory (Cichorium intybus) against free-living and parasitic stages of Cooperia oncophora

Pena-Espinoza, M. A., Williams, A. R., Thamsborg, S. M., Simonsen, H. T. & Enemark, H. L., 2017, In : Veterinary Parasitology. 243, p. 204-207

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Antibody Cross-Reactivity in Antivenom Research

Ledsgaard, L., Jenkins, T. P., Davidsen, K., Krause, K. E., Martos-Esteban, A., Engmark, M., Andersen, M. R., Lund, O. & Laustsen, A. H., 2018, In : Toxins. 10, 10, 19 p., 393.

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Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens

Malik, A., Ardalani, H., Anam, S., McNair, L. M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, H., Staerk, D. & Kongstad, K. T., 2020, In : Fitoterapia. 142, 8 p., 104522.

Research output: Contribution to journalJournal articleResearchpeer-review

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

Pena-Espinoza, M., Valente, A. H., Thamsborg, S. M., Simonsen, H. T., Boas, U., Enemark, H. L., Lopez-Munoz, R. & Williams, A. R., 2018, In : Parasites & Vectors. 11, 14 p., 475.

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Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

Woolsey, I. D., Valente, A. H., Williams, A. R., Thamsborg, S. M., Simonsen, H. T. & Enemark, H. L., 2019, In : Scientific Reports. 9, 1, 9 p., 20414.

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Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process

Calmels, C., McCann, A., Malphettes, L. & Andersen, M. R., 2018, In : Metabolic Engineering. 51, p. 9-19 11 p.

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A Review of Biotechnological Artemisinin Production in Plants

Ikram, N. K. B. K. & Simonsen, H. T., 2017, In : Frontiers in Plant Science. 8, 10 p., 1966.

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Aspergilli: Models for systems biology in filamentous fungi

Brandl, J. & Andersen, M. R., 2017, In : Current Opinion in Systems Biology. 6, p. 67-73

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Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l.

Ernst, M., Nothias, L. F., van der Hooft, J. J. J., Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Staerk, D., Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, N., 2019, In : Frontiers in Plant Science. 10, 15 p., 846.

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Basics of antibody phage display technology

Ledsgaard, L., Kilstrup, M., Karatt-Vellatt, A., McCafferty, J. & Laustsen, A. H., 2018, In : Toxins. 10, 6, 15 p., 236.

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Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy

Andersen, T. B., Rasmussen, S. A., Christensen, S. B. & Simonsen, H. T., 2019, In : Phytochemistry. 157, p. 168-174

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Biotechnological Trends in Spider and Scorpion Antivenom Development

Laustsen, A. H., Solà, M., Jappe, E. C., Oscoz Cob, S., Lauridsen, L. P. & Engmark, M., 2016, In : Toxins. 8, 8, 33 p., 226.

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Body fluid from the parasitic worm Ascaris suum inhibits broad-acting pro-inflammatory programs in dendritic cells

Arora, P., Moll, J. M., Andersen, D., Workman, C. T., Williams, A. R., Kristiansen, K. & Brix, S., 2020, In : Immunology. 159, 3, p. 322-334 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

CASCADE, a platform for controlled gene amplification for high, tunable and selection-free gene expression in yeast

Strucko, T., Buron, L. D., Jarczynska, Z. D., Nødvig, C. S., Mølgaard, L., Halkier, B. A. & Mortensen, U. H., 2017, In : Scientific Reports. 7, 12 p., 41431.

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Cell Factory Engineering

Davy, A. M., Kildegaard, H. F. & Andersen, M. R., 2017, In : Cell Systems. 4, 3, p. 262-275

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Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa

Kannangara, R., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, K. T., Stærk, D., Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, B. L., 2017, In : Nature Communications. 8, 1, 12 p., 1987 .

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Chemical Diversity of Locked Nucleic Acid-Modified Antisense Oligonucleotides Allows Optimization of Pharmaceutical Properties

Papargyri, N., Pontoppidan, M., Andersen, M. R., Koch, T. & Hagedorn, P. H., 6 Mar 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 706-717

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Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus

de Vries, R. P., Riley, R., Wiebenga, A., Aguilar-Osorio, G., Amillis, S., Uchima, C. A., Anderluh, G., Asadollahi, M., Askin, M., Barry, K., Battaglia, E., Bayram, Ö., Benocci, T., Braus-Stromeyer, S. A., Caldana, C., Cánovas, D., Cerqueira, G. C., Chen, F., Chen, W., Choi, C. & 97 others, Clum, A., dos Santos, R. A. C., de Lima Damásio, A. R., Diallinas, G., Emri, T., Fekete, E., Flipphi, M., Freyberg, S., Gallo, A., Gournas, C., Habgood, R., Hainaut, M., Harispe, M. L., Henrissat, B., Hildén, K. S., Hope, R., Hossain, A., Karabika, E., Karaffa, L., Karányi, Z., Kraševec, N., Kuo, A., Kusch, H., LaButti, K., Lagendijk, E. L., Lapidus, A., Levasseur, A., Lindquist, E., Lipzen, A., Logrieco, A. F., MacCabe, A., Mäkelä, M. R., Malavazi, I., Melin, P., Meyer, V., Mielnichuk, N., Miskei, M., Molnár, Á. P., Mulé, G., Ngan, C. Y., Orejas, M., Orosz, E., Ouedraogo, J. P., Overkamp, K. M., Park, H. S., Perrone, G., Piumi, F., Punt, P. J., Ram, A. F. J., Ramón, A., Rauscher, S., Record, E., Riaño-Pachón, D. M., Robert, V. A. R. G., Röhrig, J., Ruller, R., Salamov, A., Salih, N. S., Samson, R. A., Sándor, E., Sanguinetti, M., Schütze, T., Sepčić, K., Shelest, E., Sherlock, G., Sophianopoulou, V., Squina, F. M., Sun, J-H., Susca, A., Todd, R. B., Tsang, A., Unkles, S. E., van de Wiele, N., van Rossen-Uffink, D., de Castro Oliveira, J. V., Vesth, T. C., Visser, J., Yu, J-H., Zhou, M., Andersen, M. R., Archer, D. B., Baker, S. E., Benoit, I., Brakhage, A. A., Braus, G. H., Fischer, R., Frisvad, J. C., Goldman, G. H., Houbraken, J., Oakley, B. R., Pócsi, I., Scazzocchio, C., Seiboth, B., vanKuyk, P. A., Wortman, J. R., Dyer, P. S. & Grigoriev, I. V., 2017, In : Genome Biology (Online Edition). 18, 45 p., 28.

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Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi

Nielsen, J., Prigent, S., Grijseels, S., Workman, M., Ji, B. & Nielsen, J., 2019, In : mSystems. 4, 2, 14 p., 00012-19.

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Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Thodberg, M., Thieffry, A., Bornholdt, J., Boyd, M., Holmberg, C., Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, O. & Sandelin, A., 2019, In : Nucleic acids research. 47, 4, p. 1671-1691 21 p., gky1227.

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Cpf1 enables fast and efficient genome editing in Aspergilli

Garcia Vanegas, K., Jarczynska, Z. D., Strucko, T. & Mortensen, U. H., 2019, In : Fungal Biology and Biotechnology. 6, 6, 10 p.

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CRISPR/Cas9-multiplexed editing of Chinese hamster ovary B4Gal-T1, 2, 3 and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins

Amann, T., Hansen, A. H., Kol, S., Min Lee, G., Andersen, M. R. & Kildegaard, H. F., 2018, In : Biotechnology Journal. 13, 10, 9 p., 1800111 .

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Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping

Engmark, M., Lomonte, B., Gutiérrez, J. M., Laustsen, A. H., De Masi, F., Andersen, M. R. & Lund, O., 2017, In : P L o S Neglected Tropical Diseases (Online). 11, 7, 23 p., e0005768.

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Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper

Meyer, V., Andersen, M. R., Brakhage, A. A., Braus, G. H., Caddick, M. X., Cairns, T. C., de Vries, R. P., Haarmann, T., Hansen, K., Hertz-Fowler, C., Krappmann, S., Mortensen, U. H., Peñalva, M. A., Ram, A. F. J. & Head, R. M., 2016, In : Fungal Biology and Biotechnology. 3, 1, 17 p.

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Cyp51A mutations, Extrolite Profiles and Antifungal Susceptibility in Clinical and Environmental Isolates of the Aspergillus viridinutans Species Complex

Talbot, J. J., Frisvad, J. C., Meis, J. F., Hagen, F., Verweij, P. E., Hibbs, D. E., Lai, F., Samson, R. A., Kidd, S. E., Barrs, V. R. & Houbraken, J., 2019, In : Antimicrobial Agents and Chemotherapy. 63, 11, 13 p., e00632-19.

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Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001.

Devi, S., Kiesewalter, H. T., Kovács, R., Frisvad, J. C., Weber, T., Larsen, T. O., Kovács, Á. T. & Ding, L., 2019, In : Synthetic and Systems Biotechnology. 4, 3, p. 142-149 8 p.

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Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production

Siedler, S., Khatri, N. K., Zsohar, A., Kjærbølling, I., Vogt, M., Hammar, P., Nielsen, C. F., Marienhagen, J., Sommer, M. O. A. & Joensson, H. N., 2017, In : A C S Synthetic Biology. 6, 10, p. 1860-1869

Research output: Contribution to journalJournal articleResearchpeer-review

Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

Leth, M. L., Ejby, M., Workman, C., Ewald, D. A., Pedersen, S. S., Sternberg, C., Bahl, M. I., Licht, T. R., Aachmann, F. L., Westereng, B. & Abou Hachem, M., 2018, In : Nature Microbiology. 13 p.

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Effects of Dissolved Oxygen Concentration and Iron Addition on Immediate-early Gene Expression of Magnetospirillum gryphiswaldense MSR-1

Zhuang, S., Anyaogu, D. C., Kasama, T., Workman, M., Mortensen, U. H. & Hobley, T. J., 2017, In : FEMS Microbiology Letters. 364, 11, 21 p., fnx079.

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Effects of gamma irradiation and comparison of different extraction methods on sesquiterpene lactone yields from the medicinal plant Thapsia garganica L. (Apiaceae)

Mohamed Ibrahim, A. M., Martinez-Swatson, K. A., Benkaci-Ali, F., Cozzi, F., Zoulikha, F. & Simonsen, H. T., 2018, In : Journal of Applied Research on Medicinal and Aromatic Plants. 8, p. 26-32

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Efficient Oligo nucleotide mediated CRISPR-Cas9 Gene Editing in Aspergilli

Nødvig, C. S., Hoof, J. B., Kogle, M. E., Jarczynska, Z. D., Lehmbeck, J., Klitgaard, D. K. & Mortensen, U. H., 2018, In : Fungal Genetics and Biology. 115, p. 78-89

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Engineering Saccharomyces cerevisiae for co-utilization of D-galacturonic acid and D-glucose from citrus peel waste

Protzko, R. J., Latimer, L. N., Martinho, Z., de Reus, E., Seibert, T., Benz, J. P. & Dueber, J. E., 2018, In : Nature Communications. 9, 10 p., 5059.

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Evaluation of synthetic promoters in Physcomitrella patens

Peramuna, A., Bae, H., Rasmussen, E. K., Dueholm, B., Waibel, T., Critchley, J. H., Brzezek, K., Roberts, M. & Simonsen, H. T., 2018, In : BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 500, 2, p. 418-422

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Exploiting new biorefinery models using non-conventional yeasts and their implications for sustainability

Yamakawa, C. K., Kastell, L., Mahler, M. R., Martinez, J. L. & Mussatto, S. I., 2020, In : Bioresource Technology. 309, 9 p., 123374.

Research output: Contribution to journalJournal articleResearchpeer-review

Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus

Laustsen, A. H., Engmark, M., Clouser, C., Timberlake, S., Vigneault, F., Gutiérrez, J. M. & Lomonte, B., 2017, In : PeerJ. 5, 18 p., e2924.

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Exploring evolutionary theories of plant defence investment using field populations of the deadly carrot

Martinez-Swatson, K. A., Kjøller, R., Cozzi, F., Simonsen, H. T., Rønsted, N. & Barnes, C. J., 2019, In : Annals of Botany. 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Familial co-occurrence of congenital heart defects follows distinct patterns

Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, V. E., Brunak, S. & Larsen, L. A., 2018, In : European Heart Journal. 39, 12, p. 1015-1022

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Fluctuations in glucose availability prevent global proteome changes and physiological transition during prolonged chemostat cultivations of S. cerevisiae

Wright, N. R., Wulff, T., Palmqvist, E. A., Jørgensen, T. R., Workman, C. T., Sonnenschein, N., Rønnest, N. P. & Herrgård, M. J., 2020, In : Biotechnology and Bioengineering. 117, 7, p. 2074-2088 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal and chemical diversity in hay and wrapped haylage for equine feed

Andersen, B., Phippen, C., Frisvad, J. C., Emery, S. & Eustace, R. A., 2019, In : Mycotoxin Research. 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal communities in rice cultivated in different Brazilian agroclimatic zones: From field to market

Katsurayama, A. M., Martins, L. M., Iamanaka, B. T., Fungaro, M. H. P., Silva, J. J., Pitt, J. I., Frisvad, J. C. & Taniwaki, M. H., 2020, In : Food Microbiology. 87, 8 p., 103378.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal diversity notes 1036–1150: taxonomic and phylogenetic contributions on genera and species of fungal taxa

Hyde, K. D., Tennakoon, D. S., Jeewon, R., Bhat, D. J., Maharachchikumbura, S. S. N., Rossi, W., Leonardi, M., Lee, H. B., Mun, H. Y., Houbraken, J., Nguyen, T. T. T., Jeon, S. J., Frisvad, J. C., Wanasinghe, D. N., Lücking, R., Aptroot, A., Cáceres, M. E. S., Karunarathna, S. C., Hongsanan, S., Phookamsak, R. & 101 others, de Silva, N. I., Thambugala, K. M., Jayawardena, R. S., Senanayake, I. C., Boonmee, S., Chen, J., Luo, Z. L., Phukhamsakda, C., Pereira, O. L., Abreu, V. P., Rosado, A. W. C., Bart, B., Randrianjohany, E., Hofstetter, V., Gibertoni, T. B., Soares, A. M. D. S., Plautz, H. L., Sotão, H. M. P., Xavier, W. K. S., Bezerra, J. D. P., de Oliveira, T. G. L., de Souza-Motta, C. M., Magalhães, O. M. C., Bundhun, D., Harishchandra, D., Manawasinghe, I. S., Dong, W., Zhang, S. N., Bao, D. F., Samarakoon, M. C., Pem, D., Karunarathna, A., Lin, C. G., Yang, J., Perera, R. H., Kumar, V., Huang, S. K., Dayarathne, M. C., Ekanayaka, A. H., Jayasiri, S. C., Xiao, Y., Konta, S., Niskanen, T., Liimatainen, K., Dai, Y. C., Ji, X. H., Tian, X. M., Mešić, A., Singh, S. K., Phutthacharoen, K., Cai, L., Sorvongxay, T., Thiyagaraja, V., Norphanphoun, C., Chaiwan, N., Lu, Y. Z., Jiang, H. B., Zhang, J. F., Abeywickrama, P. D., Aluthmuhandiram, J. V. S., Brahmanage, R. S., Zeng, M., Chethana, T., Wei, D., Réblová, M., Fournier, J., Nekvindová, J., do Nascimento Barbosa, R., dos Santos, J. E. F., de Oliveira, N. T., Li, G. J., Ertz, D., Shang, Q. J., Phillips, A. J. L., Kuo, C. H., Camporesi, E., Bulgakov, T. S., Lumyong, S., Jones, E. B. G., Chomnunti, P., Gentekaki, E., Bungartz, F., Zeng, X. Y., Fryar, S., Tkalčec, Z., Liang, J., Li, G., Wen, T. C., Singh, P. N., Gafforov, Y., Promputtha, I., Yasanthika, E., Goonasekara, I. D., Zhao, R. L., Zhao, Q., Kirk, P. M., Liu, J. K., Yan, J. Y., Mortimer, P. E., Xu, J. & Doilom, M., 2019, In : Fungal Diversity. 96, 1, p. 1-242

Research output: Contribution to journalJournal articleResearchpeer-review