• Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output 2014 2020

2020

Fungal communities in rice cultivated in different Brazilian agroclimatic zones: From field to market

Katsurayama, A. M., Martins, L. M., Iamanaka, B. T., Fungaro, M. H. P., Silva, J. J., Pitt, J. I., Frisvad, J. C. & Taniwaki, M. H., 2020, In : Food Microbiology. 87, 8 p., 103378.

Research output: Contribution to journalJournal articleResearchpeer-review

5 Downloads (Pure)

Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent

Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawia, M. S., Møller, B. L. & Laursen, T., 2020, In : Phytochemistry. 170, 9 p., 112214.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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2019

3.53 Synthetic Biology: An Overview

de Carvalho, Â., Garcia Vanegas, K., Pereira, F., Theobald, S. & Takos, A., 2019, Comprehensive Biotechnology 3rd Edition. Moo-Young, M. (ed.). 3 ed. Pergamon Press, p. 659-670 12 p.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

32 Downloads (Pure)

Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l.

Ernst, M., Nothias, L. F., van der Hooft, J. J. J., Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Staerk, D., Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, N., 2019, In : Frontiers in Plant Science. 10, 15 p., 846.

Research output: Contribution to journalJournal articleResearchpeer-review

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Open Access
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Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy

Andersen, T. B., Rasmussen, S. A., Christensen, S. B. & Simonsen, H. T., 2019, In : Phytochemistry. 157, p. 168-174

Research output: Contribution to journalJournal articleResearchpeer-review

Body fluid from the parasitic worm Ascaris suum inhibits broad-acting pro-inflammatory programs in dendritic cells

Arora, P., Moll, J. M., Andersen, D., Workman, C. T., Williams, A. R., Kristiansen, K. & Brix, S., 2019, (Accepted/In press) In : Immunology. 33 p.

Research output: Contribution to journalJournal articleResearchpeer-review

102 Downloads (Pure)

Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi

Nielsen, J., Prigent, S., Grijseels, S., Workman, M., Ji, B. & Nielsen, J., 2019, In : mSystems. 4, 2, 14 p., 00012-19.

Research output: Contribution to journalJournal articleResearchpeer-review

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65 Downloads (Pure)

Comprehensive profiling of the fission yeast transcription start site activity during stress and media response

Thodberg, M., Thieffry, A., Bornholdt, J., Boyd, M., Holmberg, C., Azad, A., Workman, C. T., Chen, Y., Ekwall, K., Nielsen, O. & Sandelin, A., 2019, In : Nucleic acids research. 47, 4, p. 1671-1691 21 p., gky1227.

Research output: Contribution to journalJournal articleResearchpeer-review

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111 Downloads (Pure)

Cpf1 enables fast and efficient genome editing in Aspergilli

Garcia Vanegas, K., Jarczynska, Z. D., Strucko, T. & Mortensen, U. H., 2019, In : Fungal Biology and Biotechnology. 6, 6, 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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24 Downloads (Pure)

Cyp51A mutations, Extrolite Profiles and Antifungal Susceptibility in Clinical and Environmental Isolates of the Aspergillus viridinutans Species Complex

Talbot, J. J., Frisvad, J. C., Meis, J. F., Hagen, F., Verweij, P. E., Hibbs, D. E., Lai, F., Samson, R. A., Kidd, S. E., Barrs, V. R. & Houbraken, J., 2019, In : Antimicrobial Agents and Chemotherapy. 63, 11, 13 p., e00632-19.

Research output: Contribution to journalJournal articleResearchpeer-review

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80 Downloads (Pure)

Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001.

Devi, S., Kiesewalter, H. T., Kovács, R., Frisvad, J. C., Weber, T., Larsen, T. O., Kovács, Á. T. & Ding, L., 2019, In : Synthetic and Systems Biotechnology. 4, 3, p. 142-149 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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Design of scfab-based chimeric antibodies against Bothrops asper pi-metalloproteinase

Friis, R. U. W., Dam, S. H., Haack, A. M., Hallgren, M. B., Esteban, A. M., Andersen, M. R., Kilstrup, M. & Laustsen, A. H., 2019, In : Toxicon. 158, p. S41-S41

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Discovery of human antibodies against forest cobra toxins

Jensen, L. L., Øhlenschlæger, M., Karatt-­Vellatt, A., Andersen, M. R., Harrison, R., Casewell, N., McCafferty, J. & Laustsen, A. H., 2019, In : Toxicon. 158, Suppl. 1, p. S51-S52 2 p., 170.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Exploring evolutionary theories of plant defence investment using field populations of the deadly carrot

Martinez-Swatson, K. A., Kjøller, R., Cozzi, F., Simonsen, H. T., Rønsted, N. & Barnes, C. J., 2019, In : Annals of Botany. 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal and chemical diversity in hay and wrapped haylage for equine feed

Andersen, B., Phippen, C., Frisvad, J. C., Emery, S. & Eustace, R. A., 2019, In : Mycotoxin Research. 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal diversity notes 1036–1150: taxonomic and phylogenetic contributions on genera and species of fungal taxa

Hyde, K. D., Tennakoon, D. S., Jeewon, R., Bhat, D. J., Maharachchikumbura, S. S. N., Rossi, W., Leonardi, M., Lee, H. B., Mun, H. Y., Houbraken, J., Nguyen, T. T. T., Jeon, S. J., Frisvad, J. C., Wanasinghe, D. N., Lücking, R., Aptroot, A., Cáceres, M. E. S., Karunarathna, S. C., Hongsanan, S., Phookamsak, R. & 101 others, de Silva, N. I., Thambugala, K. M., Jayawardena, R. S., Senanayake, I. C., Boonmee, S., Chen, J., Luo, Z. L., Phukhamsakda, C., Pereira, O. L., Abreu, V. P., Rosado, A. W. C., Bart, B., Randrianjohany, E., Hofstetter, V., Gibertoni, T. B., Soares, A. M. D. S., Plautz, H. L., Sotão, H. M. P., Xavier, W. K. S., Bezerra, J. D. P., de Oliveira, T. G. L., de Souza-Motta, C. M., Magalhães, O. M. C., Bundhun, D., Harishchandra, D., Manawasinghe, I. S., Dong, W., Zhang, S. N., Bao, D. F., Samarakoon, M. C., Pem, D., Karunarathna, A., Lin, C. G., Yang, J., Perera, R. H., Kumar, V., Huang, S. K., Dayarathne, M. C., Ekanayaka, A. H., Jayasiri, S. C., Xiao, Y., Konta, S., Niskanen, T., Liimatainen, K., Dai, Y. C., Ji, X. H., Tian, X. M., Mešić, A., Singh, S. K., Phutthacharoen, K., Cai, L., Sorvongxay, T., Thiyagaraja, V., Norphanphoun, C., Chaiwan, N., Lu, Y. Z., Jiang, H. B., Zhang, J. F., Abeywickrama, P. D., Aluthmuhandiram, J. V. S., Brahmanage, R. S., Zeng, M., Chethana, T., Wei, D., Réblová, M., Fournier, J., Nekvindová, J., do Nascimento Barbosa, R., dos Santos, J. E. F., de Oliveira, N. T., Li, G. J., Ertz, D., Shang, Q. J., Phillips, A. J. L., Kuo, C. H., Camporesi, E., Bulgakov, T. S., Lumyong, S., Jones, E. B. G., Chomnunti, P., Gentekaki, E., Bungartz, F., Zeng, X. Y., Fryar, S., Tkalčec, Z., Liang, J., Li, G., Wen, T. C., Singh, P. N., Gafforov, Y., Promputtha, I., Yasanthika, E., Goonasekara, I. D., Zhao, R. L., Zhao, Q., Kirk, P. M., Liu, J. K., Yan, J. Y., Mortimer, P. E., Xu, J. & Doilom, M., 2019, In : Fungal Diversity. 96, 1, p. 1-242

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic engineering approaches to improve post-translational modification of biopharmaceuticals in different production platforms

Amann, T., Schmieder, V., Kildegaard, H. F., Borth, N. & Andersen, M. R., 2019, In : Biotechnology and Bioengineering. 116, 10, p. 2778-2796

Research output: Contribution to journalJournal articleResearchpeer-review

7 Downloads (Pure)
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Improving the production of cofactor-containing proteins: production of human hemoglobin in yeast

Ishchuk, O. P., Martinez Ruiz, J. L. & Petranovic, D., 2019, Recombinant Protein Production in Yeast . Springer, p. 243-264 22 p. (Methods in Molecular Biology, Vol. 1923).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

12 Downloads (Pure)

In planta and in silico characterization of five sesquiterpene synthases from Vitis vinifera (cv. Shiraz) berries

Dueholm, B., Drew, D. P., Sweetman, C. & Simonsen, H. T., 2019, In : Planta. 249, 1, p. 59-70 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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18 Downloads (Pure)

Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens

Ikram, N. K. K., Kashkooli, A. B., Peramuna, A. V., Krol, A. R. V. D., Bouwmeester, H. & Simonsen, H. T., 2019, In : Molecules. 24, 21, 13 p., 3822.

Research output: Contribution to journalJournal articleResearchpeer-review

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17 Downloads (Pure)

Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based Transcriptomics

Lubuta, P. J. K., Workman, M., Kerkhoven, E. J. & Workman, C. T., 2019, In : G3: Genes, Genomes, Genetics (Bethesda). 9, 12, p. 4059-4071 48 p., g3.400469.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

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Metabolic and regulatory insights from the experimental Horizontal Gene Transfer of the aurofusarin and bikaverin gene clusters to Aspergillus nidulans

de Reus, E., Nielsen, M. R. & Frandsen, R. J. N., 2019, (Accepted/In press) In : Molecular Microbiology.

Research output: Contribution to journalJournal articleResearchpeer-review

9 Downloads (Pure)

Microbiological quality of mink feed raw materials and feed production area

Lyhs, U., Frandsen, H. L., Andersen, B., Nonnemann, B., Hjulsager, C. K., Pedersen, K. & Chriél, M., 2019, In : Acta Veterinaria Scandinavica. 61, 1, 10 p., 56.

Research output: Contribution to journalJournal articleResearchpeer-review

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Monoclonal human IgGs capable of neutralizing elapid neurotoxins in vivo

Pus, U., Laustsen, A. H., Karatt-Vellatt, A., Griffiths, D. T., Oscoz, S., Andersen, M. R., Harrison, R., Casewell, N., Lomonte, B., McCafferty, J. & Gutiérrez, J. M., 2019, In : Toxicon. 158, Suppl. 1, p. S44-S44 1 p., 145.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

138 Downloads (Pure)
Open Access
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36 Downloads (Pure)

Production of terpenes and terpenoids

Simonsen, H. T. & Peramuna, A. V., 28 Mar 2019, IPC No. A01H 11/ 00 A N, Patent No. WO2019057258, 21 Sep 2018, Priority date 22 Sep 2017, Priority No. EP20170192650

Research output: Patent

Open Access
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166 Downloads (Pure)

Protease activity profiling of snake venoms using high-throughput peptide screening

Kalogeropoulos, K., Treschow, A. F., Auf Dem Keller, U., Escalante, T., Rucavado, A., Gutiérrez, J. M., Laustsen, A. H. & Workman, C. T., 2019, In : Toxins. 11, 3, 23 p., 170.

Research output: Contribution to journalJournal articleResearchpeer-review

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Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion

Ley, D., Pereira, S., Pedersen, L. E., Arnsdorf, J., Hefzi, H., Davy, A. M., Kwang Ha, T., Wulff, T., Kildegaard, H. F. & Andersen, M. R., 2019, In : Metabolic Engineering. 56, p. 120-129 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

45 Downloads (Pure)

Resistance gene-directed genome mining of 50 Aspergillus species

Kjærbølling, I., Vesth, T. & Andersen, M. R., 2019, In : mSystems. 4, 4, 13 p., e00085-19.

Research output: Contribution to journalJournal articleResearchpeer-review

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72 Downloads (Pure)

Strategies to establish the link between biosynthetic gene clusters and secondary metabolites

Kjærbølling, I., Mortensen, U. H., Vesth, T. & Andersen, M. R., 2019, In : Fungal Genetics and Biology. 130, p. 107-121 15 p.

Research output: Contribution to journalReviewResearchpeer-review

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Systematic Evaluation of Site-Specific Recombinant Gene Expression for Programmable Mammalian Cell Engineering

Pristovšek, N., Nallapareddy, S., Grav, L. M., Hefzi, H., Lewis, N. E., Rugbjerg, P., Hansen, H. G., Lee, G. M., Andersen, M. R. & Kildegaard, H. F., 2019, In : ACS Synthetic Biology. 8, 4, p. 758-774 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Taichunins A-D, Norditerpenes from Aspergillus taichungensis (IBT 19404)

Kato, H., Sebe, M., Nagaki, M., Eguchi, K., Kagiyama, I., Hitora, Y., Frisvad, J. C., Williams, R. M. & Tsukamoto, S., 2019, In : Journal of Natural Products. 82, 5, p. 1377-1381 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

140 Downloads (Pure)

The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

La Rosa, S. L., Leth, M. L., Michalak, L., Hansen, M. E., Pudlo, N. A., Glowacki, R., Pereira, G., Workman, C. T., Arntzen, M., Pope, P. B., Martens, E. C., Hachem, M. A. & Westereng, B., 2019, In : Nature Communications. 10, 1, 14 p., 905.

Research output: Contribution to journalJournal articleResearchpeer-review

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Time-resolved ATP measurements during vesicle respiration

Lin, J., Weixler, D., Daboss, S., Seibold, G. M., Andronescu, C., Schuhmann, W. & Kranz, C., 2019, In : Talanta. 205, 7 p., 120083.

Research output: Contribution to journalJournal articleResearchpeer-review

Valuable Fatty Acids in Bryophytes-Production, Biosynthesis, Analysis and Applications

Lu, Y., Eiriksson, F. F., Thorsteinsdóttir, M. & Simonsen, H. T., 2019, In : Nature Plants. 8, 11, 18 p., 524.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
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2018
192 Downloads (Pure)

A community-driven reconstruction of the Aspergillus niger metabolic network

Brandl, J., Aguilar-Pontes, M. V., Schäpe, P., Nørregaard, A., Arvas, M., Ram, A. F. J., Meyer, V., Tsang, A., de Vries, R. P. & Andersen, M. R., 2018, In : Fungal Biology and Biotechnology. 5, 16 p., 16.

Research output: Contribution to journalJournal articleResearchpeer-review

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80 Downloads (Pure)

A method for improved glycerol utilization in yeast

Strucko, T., Förster, J., Zirngibl, K. & Patil, K. R., 2018, IPC No. C12N1/16; C12N1/18; C12N1/19; C12N9/02; C12N9/10; C12N9/12; C12P1/02; C12P7/06, Patent No. WO2018127572 , 12 Jul 2018, Priority date 5 Jan 2017, Priority No. EP20170150378

Research output: Patent

Open Access
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81 Downloads (Pure)

An Online Compendium of CHO RNA-Seq Data Allows Identification of CHO Cell Line-specific Transcriptomic Signatures

Singh, A., Kildegaard, H. F. & Andersen, M. R., 2018, In : Biotechnology Journal. 13, 10, 11 p., 1800070.

Research output: Contribution to journalJournal articleResearchpeer-review

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192 Downloads (Pure)

Antibody Cross-Reactivity in Antivenom Research

Ledsgaard, L., Jenkins, T. P., Davidsen, K., Krause, K. E., Martos-Esteban, A., Engmark, M., Andersen, M. R., Lund, O. & Laustsen, A. H., 2018, In : Toxins. 10, 10, 19 p., 393.

Research output: Contribution to journalJournal articleResearchpeer-review

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148 Downloads (Pure)

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

Pena-Espinoza, M., Valente, A. H., Thamsborg, S. M., Simonsen, H. T., Boas, U., Enemark, H. L., Lopez-Munoz, R. & Williams, A. R., 2018, In : Parasites & Vectors. 11, 14 p., 475.

Research output: Contribution to journalJournal articleResearchpeer-review

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34 Downloads (Pure)

Application of a curated genome-scale metabolic model of CHO DG44 to an industrial fed-batch process

Calmels, C., McCann, A., Malphettes, L. & Andersen, M. R., 2018, In : Metabolic Engineering. 51, p. 9-19 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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401 Downloads (Pure)

Basics of antibody phage display technology

Ledsgaard, L., Kilstrup, M., Karatt-Vellatt, A., McCafferty, J. & Laustsen, A. H., 2018, In : Toxins. 10, 6, 15 p., 236.

Research output: Contribution to journalJournal articleResearchpeer-review

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158 Downloads (Pure)

Correction to: Industrial antifoam agents impair ethanol fermentation and induce stress responses in yeast cells

Nielsen, J. C. F., Senne de Oliveira Lino, F., Rasmussen, T. G., Thykær, J., Workman, C. & Basso, T. O., 2018, In : Applied Microbiology and Biotechnology. 102, 1, p. 513-513 1 p.

Research output: Contribution to journalComment/debateResearchpeer-review

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58 Downloads (Pure)

CRISPR/Cas9-multiplexed editing of Chinese hamster ovary B4Gal-T1, 2, 3 and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins

Amann, T., Hansen, A. H., Kol, S., Min Lee, G., Andersen, M. R. & Kildegaard, H. F., 2018, In : Biotechnology Journal. 13, 10, 9 p., 1800111 .

Research output: Contribution to journalJournal articleResearchpeer-review

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395 Downloads (Pure)

Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

Leth, M. L., Ejby, M., Workman, C., Ewald, D. A., Pedersen, S. S., Sternberg, C., Bahl, M. I., Licht, T. R., Aachmann, F. L., Westereng, B. & Abou Hachem, M., 2018, In : Nature Microbiology. 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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21 Downloads (Pure)

Effects of gamma irradiation and comparison of different extraction methods on sesquiterpene lactone yields from the medicinal plant Thapsia garganica L. (Apiaceae)

Mohamed Ibrahim, A. M., Martinez-Swatson, K. A., Benkaci-Ali, F., Cozzi, F., Zoulikha, F. & Simonsen, H. T., 2018, In : Journal of Applied Research on Medicinal and Aromatic Plants. 8, p. 26-32

Research output: Contribution to journalJournal articleResearchpeer-review

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244 Downloads (Pure)

Efficient Oligo nucleotide mediated CRISPR-Cas9 Gene Editing in Aspergilli

Nødvig, C. S., Hoof, J. B., Kogle, M. E., Jarczynska, Z. D., Lehmbeck, J., Klitgaard, D. K. & Mortensen, U. H., 2018, In : Fungal Genetics and Biology. 115, p. 78-89

Research output: Contribution to journalJournal articleResearchpeer-review

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132 Downloads (Pure)

Engineering Saccharomyces cerevisiae for co-utilization of D-galacturonic acid and D-glucose from citrus peel waste

Protzko, R. J., Latimer, L. N., Martinho, Z., de Reus, E., Seibert, T., Benz, J. P. & Dueber, J. E., 2018, In : Nature Communications. 9, 10 p., 5059.

Research output: Contribution to journalJournal articleResearchpeer-review

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