• Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output

2020

Anthelmintic and metabolomic analyses of chicory (Cichorium intybus) identify an industrial by-product with potent in vitro antinematodal activity

Pena-Espinoza, M. A., Valente, A. H., Bornancin, L., Simonsen, H. T., Thamsborg, S. M., Williams, A. R. & López-Muñoz, R., 2020, In : Veterinary Parasitology. 280, 11 p., 109088.

Research output: Contribution to journalJournal articleResearchpeer-review

Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent

Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawia, M. S., Møller, B. L. & Laursen, T., 2020, In : Phytochemistry. 170, 9 p., 112214.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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97 Downloads (Pure)

Thapsigargins and induced chemical defence in Thapsia garganica

Martinez-Swatson, K., Quiñonero-López, C., Ernst, M., Rønsted, N., Barnes, C. J. & Simonsen, H. T., 2020, (Accepted/In press) In : Chemoecology. 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

Woolsey, I. D., Valente, A. H., Williams, A. R., Thamsborg, S. M., Simonsen, H. T. & Enemark, H. L., 2019, In : Scientific Reports. 9, 1, 9 p., 20414.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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42 Downloads (Pure)

Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l.

Ernst, M., Nothias, L. F., van der Hooft, J. J. J., Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Staerk, D., Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, N., 2019, In : Frontiers in Plant Science. 10, 15 p., 846.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
95 Downloads (Pure)

Biosynthesis of tovarol and other sesquiterpenoids in Thapsia laciniata Rouy

Andersen, T. B., Rasmussen, S. A., Christensen, S. B. & Simonsen, H. T., 2019, In : Phytochemistry. 157, p. 168-174

Research output: Contribution to journalJournal articleResearchpeer-review

Exploring evolutionary theories of plant defence investment using field populations of the deadly carrot

Martinez-Swatson, K. A., Kjøller, R., Cozzi, F., Simonsen, H. T., Rønsted, N. & Barnes, C. J., 2019, In : Annals of Botany. 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

In planta and in silico characterization of five sesquiterpene synthases from Vitis vinifera (cv. Shiraz) berries

Dueholm, B., Drew, D. P., Sweetman, C. & Simonsen, H. T., 2019, In : Planta. 249, 1, p. 59-70 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
68 Downloads (Pure)

Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens

Ikram, N. K. K., Kashkooli, A. B., Peramuna, A. V., Krol, A. R. V. D., Bouwmeester, H. & Simonsen, H. T., 2019, In : Molecules. 24, 21, 13 p., 3822.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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72 Downloads (Pure)

Parasites and plants - bioactive compounds with anti-parasitic effect from Cichorium intybus

Valente, A. H., de Roode, B. M., Williams, A. R., Simonsen, H. T. & Thamsborg, S. M., 2019, In : Planta Medica. 85, 18, 1 p., 1420.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Production of terpenes and terpenoids

Simonsen, H. T. & Peramuna, A. V., 28 Mar 2019, IPC No. A01H 11/ 00 A N, Patent No. WO2019057258, 21 Sep 2018, Priority date 22 Sep 2017, Priority No. EP20170192650

Research output: Patent

Open Access
File
118 Downloads (Pure)

Valuable Fatty Acids in Bryophytes-Production, Biosynthesis, Analysis and Applications

Lu, Y., Eiriksson, F. F., Thorsteinsdóttir, M. & Simonsen, H. T., 2019, In : Nature Plants. 8, 11, 18 p., 524.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
52 Downloads (Pure)
2018

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

Pena-Espinoza, M., Valente, A. H., Thamsborg, S. M., Simonsen, H. T., Boas, U., Enemark, H. L., Lopez-Munoz, R. & Williams, A. R., 2018, In : Parasites & Vectors. 11, 14 p., 475.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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226 Downloads (Pure)

Effects of gamma irradiation and comparison of different extraction methods on sesquiterpene lactone yields from the medicinal plant Thapsia garganica L. (Apiaceae)

Mohamed Ibrahim, A. M., Martinez-Swatson, K. A., Benkaci-Ali, F., Cozzi, F., Zoulikha, F. & Simonsen, H. T., 2018, In : Journal of Applied Research on Medicinal and Aromatic Plants. 8, p. 26-32

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
85 Downloads (Pure)

Evaluation of synthetic promoters in Physcomitrella patens

Peramuna, A., Bae, H., Rasmussen, E. K., Dueholm, B., Waibel, T., Critchley, J. H., Brzezek, K., Roberts, M. & Simonsen, H. T., 2018, In : BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 500, 2, p. 418-422

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
109 Downloads (Pure)

Physcomitrella patens, a versatile synthetic biology chassis

Reski, R., Bae, H. & Simonsen, H. T., 2018, In : Plant Cell Reports. 37, 10, p. 1409-1417

Research output: Contribution to journalJournal articleResearchpeer-review

Use of a temporary immersion bioreactor system for the sustainable production of thapsigargin in shoot cultures of Thapsia garganica

López, C. Q., Corral, P., Lorrain-Lorrette, B., Martinez-Swatson, K., Michoux, F. & Simonsen, H. T., 2018, In : Plant Methods. 14, 1, 17 p., 79.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
191 Downloads (Pure)
2017

Anthelmintic effects of forage chicory (Cichorium intybus) against free-living and parasitic stages of Cooperia oncophora

Pena-Espinoza, M. A., Williams, A. R., Thamsborg, S. M., Simonsen, H. T. & Enemark, H. L., 2017, In : Veterinary Parasitology. 243, p. 204-207

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
230 Downloads (Pure)

A Review of Biotechnological Artemisinin Production in Plants

Ikram, N. K. B. K. & Simonsen, H. T., 2017, In : Frontiers in Plant Science. 8, 10 p., 1966.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
407 Downloads (Pure)

Fragrant plants used as air fresheners in private households

Simonsen, H. T., 2017, Book of Abstracts, Sustain 2017. Technical University of Denmark, 1 p. G-3

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
File
61 Downloads (Pure)

Localization and in-vivo characterization of thapsia garganica CYP76AE2 indicates a role in thapsigargin biosynthesis

Andersen, T. B., Martinez-Swatson, K. A., Rasmussen, S. A., Boughton, B. A., Jørgensen, K., Andersen-Ranberg, J., Nyberg, N., Christensen, S. B. & Simonsen, H. T., 1 May 2017, In : Plant Physiology. 174, 1, p. 56-72 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
299 Downloads (Pure)

Stable production of the antimalarial drug artemisinin in the moss Physcomitrella patens

Binti Khairul Ikram, N. K., Kashkooli, A. B., Peramuna, A. V., van der Krol, A. R., Bouwmeester, H. & Simonsen, H. T., 2017, In : Frontiers in Bioengineering and Biotechnology. 5, 47, 20 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
337 Downloads (Pure)
2016

Increasing Oil Bodies in Physcomitrella patens by Overexpressing Oil Body- Associated Proteins

Bae, H., Peramuna, A. V. & Simonsen, H. T., 2016.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access