Natural Products Genome Mining

Publications

Publications per year 2020 2021 2022 2023 2023

• 36 Journal article
• 2 Review
• 1 Book chapter
• 1 Conference abstract for conference
• 2 More
  • 1 Editorial
  • 1 Letter

Publications per year

Publications per year

Search results

• 2023

  An automated workflow for multi-omics screening of microbial model organisms

  Donati, S., Mattanovich, M., Hjort, P., Baallal Jacobsen, S. A., Blomquist, S. D., Mangaard, D., Gurdo, N., Pacheco Pastor, F., Maury, J., Hanke, R., Herrgård, M. J., Wulff, T., Jakociunas, T., Nielsen, L. K. & McCloskey, D., 2023, In: n p j Systems Biology and Applications. 9, 12 p., 14.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Organisms 100%
  • Screening 100%
  • Workflows 100%
  • Models 100%
  • Sample 60%
  70 Downloads (Pure)

• antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation

  Blin, K., Shaw, S., Augustijn, H. E., Reitz, Z. L., Biermann, F., Alanjary, M., Fetter, A., Terlouw, B. R., Metcalf, W. W., Helfrich, E. J. N., van Wezel, G. P., Medema, M. H. & Weber, T., 2023, (Accepted/In press) In: Nucleic Acids Research.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  • Gene Cluster 100%
  • Regulatory Mechanism 100%
  • Fungus 50%
  • Metabolite 50%
  • Metabolic Pathway 50%

• Complete Genome Sequences of the Two Strains Methylorubrum extorquens NBC_00036 and NBC_00404

  Faurdal, D., Jørgensen, T. S., Alvarez-Arevalo, M., Mourched, A-S., Sterndorff, E. B., Charusanti, P. & Weber, T., 2023, In: Microbiology Resource Announcements. 12, 7, p. e0011523

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File
  10 Downloads (Pure)

• Embryogenesis of a calanoid copepod analyzed by transcriptomics

  Acebal, M. C., Dalgaard, L. T., Jørgensen, T. S. & Hansen, B. W., 2023, In: Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 45, 11 p., 101054.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Copepod 100%
  • Calanoid 100%
  • Transcriptomics 100%
  • Embryogenesis 100%
  • Transcriptome 42%
  71 Downloads (Pure)

• Extraction and Oxford Nanopore sequencing of genomic DNA from filamentous Actinobacteria

  Alvarez-Arevalo, M., Sterndorff, E. B., Faurdal, D., Jørgensen, T. S., Mourched, A-S., Vuksanovic, O., Saha, S. & Weber, T., 2023, In: STAR Protocols. 4, 1, 24 p., 101955.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Actinobacteria 100%
  • Sequencing 100%
  • Extraction 100%
  • DNA 100%
  • Molecular Weight 66%
  118 Downloads (Pure)

• Identification and heterologous expression of the globomycin biosynthetic gene cluster

  Oves-Costales, D., Gren, T., Sterndorff, E. B., Martín, J., Ortiz-López, F. J., Jørgensen, T. S., Jiang, X., Román-Hurtado, F., Reyes, F., Genilloud, O. & Weber, T., 2023, In: Synthetic and Systems Biotechnology. 8, 2, p. 206-212 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Gene Cluster 100%
  • Heterologous Expression 100%
  • Anabolism 80%
  • Biosynthesis 80%
  • Streptomyces 40%
  16 Downloads (Pure)

• MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

  Terlouw, B. R., Blin, K., Navarro-Muñoz, J. C., Avalon, N. E., Chevrette, M. G., Egbert, S., Lee, S., Meijer, D., Recchia, M. J. J., Reitz, Z. L., van Santen, J. A., Selem-Mojica, N., Tørring, T., Zaroubi, L., Alanjary, M., Aleti, G., Aguilar, C., Al-Salihi, S. A. A., Augustijn, H. E., Avelar-Rivas, J. A., & 62 othersAvitia-Domínguez, L. A., Barona-Gómez, F., Bernaldo-Agüero, J., Bielinski, V. A., Biermann, F., Booth, T. J., Carrion Bravo, V. J., Castelo-Branco, R., Chagas, F. O., Cruz-Morales, P., Du, C., Duncan, K. R., Gavriilidou, A., Gayrard, D., Gutiérrez-García, K., Haslinger, K., Helfrich, E. J. N., van der Hooft, J. J. J., Jati, A. P., Kalkreuter, E., Kalyvas, N., Kang, K. B., Kautsar, S., Kim, W., Kunjapur, A. M., Li, Y-X., Lin, G-M., Loureiro, C., Louwen, J. J. R., Louwen, N. L. L., Lund, G., Parra, J., Philmus, B., Pourmohsenin, B., Pronk, L. J. U., Rego, A., Rex, D. A. B., Robinson, S., Rosas-Becerra, L. R., Roxborough, E. T., Schorn, M. A., Scobie, D. J., Singh, K. S., Sokolova, N., Tang, X., Udwary, D., Vigneshwari, A., Vind, K., Vromans, S. P. J. M., Waschulin, V., Williams, S. E., Winter, J. M., Witte, T. E., Xie, H., Yang, D., Yu, J., Zdouc, M., Zhong, Z., Collemare, J., Linington, R. G., Weber, T. & Medema, M. H., 2023, In: Nucleic Acids Research. 51, D1, p. D603–D610 8 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Gene Cluster 100%
  • Exercise 100%
  • Data Base 50%
  • Nested Gene 16%
  • Structure Activity Relation 16%
  42 Downloads (Pure)

• Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain Streptomyces albidoflavus J1074

  Dolya, B., Hryhorieva, O., Sorochynska, K., Lopatniuk, M., Ostash, I., Tseduliak, V-M., Sterndorff, E. B., Jørgensen, T. S., Gren, T., Dacyuk, Y., Weber, T., Luzhetskyy, A., Fedorenko, V. & Ostash, B., 2023, In: Microorganisms. 11, 1176.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Mutation 100%
  • Heterologous Expression 100%
  • Mutant 100%
  • Metabolite 33%
  • Gene Cluster 33%
  7 Downloads (Pure)

• SpikeSeq: A rapid, cost efficient and simple method to identify SARS-CoV-2 variants of concern by Sanger sequencing part of the spike protein gene

  Jørgensen, T. S., Pedersen, M. S., Blin, K., Kuntke, F., Salling, H. K., Marvig, R. L., Michaelsen, T. Y., Albertsen, M. & Larsen, H., 2023, In: Journal of Virological Methods. 312, 6 p., 114648.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Nested Gene 100%
  • SARS Coronavirus 100%
  • Protein 100%
  • Sample 100%
  • Spike 100%
  33 Downloads (Pure)

• Systems Analysis of Highly Multiplexed CRISPR-Base Editing in Streptomycetes

  Whitford, C. M., Gren, T., Palazzotto, E., Lee, S. Y., Tong, Y. & Weber, T., 2023, (Accepted/In press) In: ACS Synthetic Biology. 14 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Clustered Regularly Interspaced Short Palindromic Repeat 100%
  • Streptomycetaceae 100%
  • Analysis 100%
  • Base 100%
  • System Analysis 100%

• UmetaFlow: an untargeted metabolomics workflow for high-throughput data processing and analysis

  Kontou, E. E., Walter, A., Alka, O., Pfeuffer, J., Sachsenberg, T., Mohite, O. S., Nuhamunada, M., Kohlbacher, O. & Weber, T., 2023, In: Journal of Cheminformatics. 15, 12 p., 52.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Data Set 100%
  • Data Processing 100%
  • High Throughput 100%
  • Throughput Data 100%
  • Workflows 100%
  18 Downloads (Pure)
• 2022

  A Versatile in Vivo DNA Assembly Toolbox for Fungal Strain Engineering

  Jarczynska, Z. D., Garcia Vanegas, K., Deichmann, M., Nørskov Jensen, C., Scheeper, M. J., Futyma, M. E., Strucko, T., Jares Contesini, F., Sparholt Jørgensen, T., Blæsbjerg Hoof, J. & Hasbro Mortensen, U., 2022, In: ACS Synthetic Biology. 11, 10, p. 3251-3263 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Fungal Strain 100%
  • DNA 100%
  • Genetic Engineering 50%
  • Yeast 33%
  • Filamentous Fungus 33%
  69 Downloads (Pure)

• Complete Genome Sequence of the Collinolactone Producer Streptomyces sp. Strain Go40/10

  Sterndorff, E. B., Jørgensen, T. S., Garzon, J. F. G., Schmid, J. C., Grond, S. & Weber, T., 2022, In: Microbiology Resource Announcements. 11, 8, 2 p.

  Research output: Contribution to journal › Journal article › Communication

  Open Access

  File

  • Streptomyces 100%
  • Strains 100%
  • Electric Potential 100%
  • Chromosomes 50%
  • Secondary Metabolite 50%
  33 Downloads (Pure)

• Critical Assessment of Metagenome Interpretation: the second round of challenges

  Meyer, F., Fritz, A., Deng, Z-L., Koslicki, D., Lesker, T. R., Gurevich, A., Robertson, G., Alser, M., Antipov, D., Beghini, F., Bertrand, D., Brito, J. J., Brown, C. T., Buchmann, J., Buluç, A., Chen, B., Chikhi, R., Clausen, P. T. L. C., Cristian, A., Dabrowski, P. W., & 83 othersDarling, A. E., Egan, R., Eskin, E., Georganas, E., Goltsman, E., Gray, M. A., Hansen, L. H., Hofmeyr, S., Huang, P., Irber, L., Jia, H., Jørgensen, T. S., Kieser, S. D., Klemetsen, T., Kola, A., Kolmogorov, M., Korobeynikov, A., Kwan, J., LaPierre, N., Lemaitre, C., Li, C., Limasset, A., Malcher-Miranda, F., Mangul, S., Marcelino, V. R., Marchet, C., Marijon, P., Meleshko, D., Mende, D. R., Milanese, A., Nagarajan, N., Nissen, J., Nurk, S., Oliker, L., Paoli, L., Peterlongo, P., Piro, V. C., Porter, J. S., Rasmussen, S., Rees, E. R., Reinert, K., Renard, B., Robertsen, E. M., Rosen, G. L., Ruscheweyh, H-J., Sarwal, V., Segata, N., Seiler, E., Shi, L., Sun, F., Sunagawa, S., Sørensen, S. J., Thomas, A., Tong, C., Trajkovski, M., Tremblay, J., Uritskiy, G., Vicedomini, R., Wang, Z., Wang, Z., Wang, Z., Warren, A., Willassen, N. P., Yelick, K., You, R., Zeller, G., Zhao, Z., Zhu, S., Zhu, J., Garrido-Oter, R., Gastmeier, P., Hacquard, S., Häußler, S., Khaledi, A., Maechler, F., Mesny, F., Radutoiu, S., Schulze-Lefert, P., Smit, N., Strowig, T., Bremges, A., Sczyrba, A. & McHardy, A. C., 2022, In: Nature Methods. 19, 4, p. 429-440 12 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Metagenome 100%
  • Virus 50%
  • Plasmid 25%
  • Archaeon 25%
  • Memory 25%
  86 Downloads (Pure)

• Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family

  Carretero-Molina, D., Ortiz-López, F. J., Gren, T., Oves-Costales, D., Martín, J., Román-Hurtado, F., Sparholt Jørgensen, T., de la Cruz, M., Díaz, C., Vicente, F., Blin, K., Reyes, F., Weber, T. & Genilloud, O., 2022, In: Organic Chemistry Frontiers. 9, 2, p. 462-470 9 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Molecular Cluster 100%
  • Stereochemistry 100%
  • Amycolatopsis 100%
  • Absolute Configuration 50%
  • Macrolide Antibiotic Agent 50%

• High-quality genome-scale metabolic network reconstruction of probiotic bacterium Escherichia coli Nissle 1917

  van ‘t Hof, M., Mohite, O. S., Monk, J. M., Weber, T., Palsson, B. O. & Sommer, M. O. A., 2022, In: BMC Bioinformatics. 23, 1, 23 p., 566.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Bacterium 100%
  • Escherichia coli 100%
  • Probiotic Agent 100%
  • Metabolic Network 100%
  • Reconstruction 100%
  25 Downloads (Pure)

• Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp.

  Nielsen, J. B., Gren, T., Mohite, O. S., Jørgensen, T. S., Klitgaard, A. K., Mourched, A-S., Blin, K., Oves-Costales, D., Genilloud, O., Larsen, T. O., Tanner, D., Weber, T., Gotfredsen, C. H. & Charusanti, P., 2022, In: ACS chemical biology. 17, 9, p. 2411-2417 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Serine 100%
  • Gene Cluster 100%
  • Streptomyces 100%
  • Anabolism 66%
  • Proline 66%

• Long-Read Metagenome-Assembled Genomes Improve Identification of Novel Complete Biosynthetic Gene Clusters in a Complex Microbial Activated Sludge Ecosystem

  Sánchez-Navarro, R., Nuhamunada, M., Mohite, O. S., Wasmund, K., Albertsen, M., Gram, L., Nielsen, P. H., Weber, T. & Singleton, C. M., 2022, In: mSystems. 7, 6, 15 p., e0063222.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Gene Cluster 100%
  • Metagenome 100%
  • Electric Potential 40%
  • Metabolite 26%
  • Genus 13%
  24 Downloads (Pure)

• Microbial safety and protein composition of birch sap

  Sancho, A. I., Birk, T., Gregersen, J. M., Rønne, T., Hornslet, S. E., Madsen, A. M. & Bøgh, K. L., 2022, In: Journal of Food Composition and Analysis. 107, 9 p., 104347.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Birch 100%
  • Protein 100%
  • Microflora 44%
  • Life 33%
  • Bacterium 22%
  90 Downloads (Pure)

• Pangenome analysis of Enterobacteria reveals richness of secondary metabolite gene clusters and their associated gene sets

  Mohite, O. S., Lloyd, C. J., Monk, J. M., Weber, T. & Palsson, B. O., 2022, In: Synthetic and Systems Biotechnology. 7, 3, p. 900-910 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Nested Gene 100%
  • Enterobacteriaceae 100%
  • Gene Cluster 100%
  • Secondary Metabolite 100%
  • Gene 100%
  57 Downloads (Pure)

• The diversity, structure and function of microbial communities changes across aging process of tobacco leaves

  Wang, F., Jin, Y., Chen, X., Zhang, Y., Jiang, X., Zhang, G., Chen, G., Yang, M., Leng, F., Li, H., Wu, L. & Zhang, H., 2022, In: Environmental Research Communications. 4, 9, 14 p., 095012.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Aging 100%
  • Fungus 33%
  • Metabolism 22%
  • Degradation 11%
  • Proteobacteria 11%
  11 Downloads (Pure)
• 2021

  Activation and identification of a griseusin cluster in streptomyces sp. Ca-256286 by employing transcriptional regulators and multi-omics methods

  Beck, C., Gren, T., Ortiz-López, F. J., Jørgensen, T. S., Carretero-Molina, D., Serrano, J. M., Tormo, J. R., Oves-Costales, D., Kontou, E. E., Mohite, O. S., Mingyar, E., Stegmann, E., Genilloud, O. & Weber, T., 2021, In: Molecules. 26, 24 p., 6580.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Gene Cluster 100%
  • Streptomyces 100%
  • Secondary Metabolite 28%
  • Proteomics 14%
  • Metabolic Engineering 14%
  69 Downloads (Pure)

• An improved direct metamobilome approach increases the detection of larger-sized circular elements across kingdoms

  Alanin, K. W. S., Jørgensen, T. S., Browne, P. D., Petersen, B., Riber, L., Kot, W. & Hansen, L. H., 2021, In: Plasmid. 115, 102576.

  Research output: Contribution to journal › Journal article › Research › peer-review

  File

  • Plasmid 100%
  • Multiple Displacement Amplification 100%
  • Mobile Genetic Elements 66%
  • DNA 66%
  • Sequencing 33%
  64 Downloads (Pure)

• antiSMASH 6.0: improving cluster detection and comparison capabilities

  Blin, K., Shaw, S., Kloosterman, A. M., Charlop-Powers, Z., van Wezel, G. P., Medema, M. H. & Weber, T., 2021, In: Nucleic Acids Research. 7 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Detection 100%
  • Capability Comparison 100%
  • Gene Cluster 100%
  • Algorithms 33%
  • Research Worker 33%
  555 Downloads (Pure)

• A regulator based “semi-targeted” approach to activate silent biosynthetic gene clusters

  Mingyar, E., Mühling, L., Kulik, A., Winkler, A., Wibberg, D., Kalinowski, J., Blin, K., Weber, T., Wohlleben, W. & Stegmann, E., 2 Jul 2021, In: International Journal of Molecular Sciences . 22, 14, 14 p., 7567.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Gene Cluster 100%
  • Streptomyces 100%
  • Regulator Gene 60%
  • Microorganism 20%
  • Promoter Region 20%
  74 Downloads (Pure)

• ARTS-DB: a database for antibiotic resistant targets

  Mungan, M. D., Blin, K. & Ziemert, N., 2021, In: Nucleic Acids Research. 50, D1, p. D736–D740 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Antibiotics 100%
  • Data Base 100%
  • Database 100%
  • Gene Cluster 70%
  • Bacterium 20%
  38 Downloads (Pure)

• A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing

  Tong, Y., Jørgensen, T. S., Whitford, C. M., Weber, T. & Lee, S. Y., 2021, In: Nature Communications. 12, 1, 11 p., 5206.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Escherichia coli 100%
  • Genetic Engineering 100%
  • CRISPR 100%
  • Clustered Regularly Interspaced Short Palindromic Repeat 100%
  • Nucleotide 50%
  92 Downloads (Pure)

• Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p

  Tong, Y., Zhang, J., Sun, N., Wang, X. M., Wei, Q., Zhang, Y., Huang, R., Pu, Y., Dai, H., Ren, B., Pei, G., Song, F., Zhu, G., Wang, X., Xia, X., Chen, X., Jiang, L., Wang, S., Ouyang, L., Xie, N., & 7 othersZhang, B., Jiang, Y., Liu, X., Calderone, R., Bai, F., Zhang, L. & Alterovitz, G., 2021, In: Science Bulletin. 66, 18, p. 1895-1905 11 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Effusion 100%
  • Multidrug Resistance 100%
  • Drug 100%
  • Chemotherapeutic Agent 100%
  • Pump 100%
  100 Downloads (Pure)

• Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters

  Gren, T., Whitford, C. M., Mohite, O. S., Jørgensen, T. S., Kontou, E. E., Nielsen, J. B., Lee, S. Y. & Weber, T., Dec 2021, In: Scientific Reports. 11, 1, 14 p., 18301.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Electric Potential 100%
  • Gene Cluster 100%
  • Host 100%
  • Heterologous Expression 100%
  • Streptomyces 100%
  59 Downloads (Pure)

• Complete genome sequence of Amycolatopsis sp. CA-230715, encoding a 35-module type I polyketide synthase

  Jørgensen, T. S., Gren, T., Oves-Costales, D., Ortiz-López, F. J., Carretero-Molina, D., González, I., Blin, K., Genilloud, O. & Weber, T., Sept 2021, In: Microbiology Resource Announcements. 10, 38, e00805-21.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Amycolatopsis 100%
  • Polyketide Synthase 100%
  • Chromosomes 25%
  • Nanopore 25%
  • Technology 25%
  59 Downloads (Pure)

• Complete genome sequence of Streptomyces sp. strain CA-256286

  Beck, C., Gren, T., Jørgensen, T. S., González, I., Román-Hurtado, F., Oves-Costales, D., Genilloud, O. & Weber, T., Jun 2021, In: Microbiology Resource Announcements. 10, 22, p. e00290-21

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Nucleotide 100%
  • Streptomyces 100%
  • Strains 100%
  • Secondary Metabolite 50%
  • Chromosome 25%
  51 Downloads (Pure)

• Complete genome sequence of the rare actinobacterium Kutzneria sp. Strain CA-103260

  Jørgensen, T. S., Gren, T., Kontou, E. E., González, I., Román-Hurtado, F., Oves-Costales, D., Thomsen, E., Charusanti, P., Genilloud, O. & Weber, T., 2021, In: Microbiology Resource Announcements. 10, 30, 2 p., e00499.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Actinobacteria 100%
  • Chromosome 50%
  • Sequencing 50%
  47 Downloads (Pure)

• Computational Applications in Secondary Metabolite Discovery (CAiSMD): an online workshop

  Ntie-Kang, F., Telukunta, K. K., Fobofou, S. A. T., Chukwudi Osamor, V., Egieyeh, S. A., Valli, M., Djoumbou-Feunang, Y., Sorokina, M., Stork, C., Mathai, N., Zierep, P., Chávez-Hernández, A. L., Duran-Frigola, M., Babiaka, S. B., Tematio Fouedjou, R., Eni, D. B., Akame, S., Arreyetta-Bawak, A. B., Ebob, O. T., Metuge, J. A., & 15 othersBekono, B. D., Isa, M. A., Onuku, R., Shadrack, D. M., Musyoka, T. M., Patil, V. M., van der Hooft, J. J. J., da Silva Bolzani, V., Medina-Franco, J. L., Kirchmair, J., Weber, T., Tastan Bishop, Ö., Medema, M. H., Wessjohann, L. A. & Ludwig-Müller, J., Dec 2021, In: Journal of Cheminformatics. 13, 1, 11 p., 64.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Application 100%
  • Websites 50%
  • Potential Application 50%
  • Academia 50%
  • Modern Computer 50%
  73 Downloads (Pure)

• Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260

  Kontou, E. E., Gren, T., Ortiz-López, F. J., Thomsen, E., Oves-Costales, D., Díaz, C., de la Cruz, M., Jiang, X., Jørgensen, T. S., Blin, K., Charusanti, P., Reyes, F., Genilloud, O. & Weber, T., 2021, In: ACS chemical biology. 16, 8, p. 1456-1468 13 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Genus 100%
  • Macrolides 100%
  • Macrolide Antibiotic Agent 100%
  • Macrolide 100%
  • Gene Cluster 75%

• The Design-Build-Test-Learn cycle for metabolic engineering of Streptomycetes

  Whitford, C. M., Cruz-Morales, P., Keasling, J. D. & Weber, T., 2021, In: Essays in Biochemistry. 15 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  • Metabolic Engineering 100%
  • Streptomycetaceae 100%
  • Metabolic 100%
  • Antimicrobial Agent 75%
  • Metabolite 50%

• The Structure of Cyclodecatriene Collinolactone, its Biosynthesis, and Semisynthetic Analogues: Effects of Monoastral Phenotype and Protection from Intracellular Oxidative Stress

  Schmid, J. C., Frey, K., Scheiner, M., Garzón, J. F. G., Stafforst, L., Fricke, J-N., Schuppe, M., Schiewe, H., Zeeck, A., Weber, T., Usón, I., Kemkemer, R., Decker, M. & Grond, S., 2021, In: Angewandte Chemie - International Edition. 60, 43, p. 23212-23216 5 p.

  Research output: Contribution to journal › Journal article › Research › peer-review

  Open Access

  File

  • Oxidative Stress 100%
  • Biosynthesis 100%
  • Structure 100%
  • Neuroprotection 100%
  • Oxidation Reaction 50%
  156 Downloads (Pure)