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2023
Adaptive laboratory evolution of Bacillus subtilis to overcome toxicity of lignocellulosic hydrolysate derived from Distiller's dried grains with solubles (DDGS)
Driessen, J. L. S. P., Johnsen, J., Pogrebnyakov, I., Mohamed, E. T. T., Mussatto, S. I., Feist, A. M., Jensen, S. I. & Nielsen, A. T., 2023, In: Metabolic Engineering Communications. 16, 11 p., e00223.Research output: Contribution to journal › Journal article › Research › peer-review
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2022
Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients
Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, H. K., Nielsen, S. D. & Perch, M., 2022, In: Pathogens. 11, 2, 11 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
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Catalytic production of long-chain hydrocarbons suitable for jet-fuel use from fermentation-derived oxygenates
Doménech, P., Pogrebnyakov, I., Nielsen, A. T. & Riisager, A., 2022, In: Green Chemistry. 24, 9, p. 3461-3474 14 p.Research output: Contribution to journal › Review › peer-review
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Diagnostic criteria of CNS infection in patients with external ventricular drainage after traumatic brain injury: a pilot study
Willer-Hansen, R. S., Olsen, M. H., Hauerberg, J., Johansen, H. K., Andersen, Å. B. & Møller, K., 2022, In: Acta Anaesthesiologica Scandinavica. 66, 4, p. 507-515 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial: Pseudomonas aeruginosa Pathogenesis: Virulence, Antibiotic Tolerance and Resistance, Stress Responses and Host-Pathogen Interactions
Rossi, E., Ghoul, M. & La Rosa, R., 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 860314.Research output: Contribution to journal › Editorial › peer-review
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Intensive land-based activities increase the potential risk of benzo[α]pyrene (BaP) to aquatic ecosystems and human health in coastal areas of China
Cao, X., Huo, S., Zhang, H., Zhao, X., Pang, C., Ma, C., Zheng, J. & Wu, F., 2022, In: Journal of cleaner production. 371, 11 p., 133571.Research output: Contribution to journal › Journal article › Research › peer-review
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Inter-species interactions alter antibiotic efficacy in bacterial communities
Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, H. K., Pitchford, J. W. & Friman, V-P., 2022, In: ISME Journal. 16, p. 812–821 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams
Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, H. K., Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5, 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance
Goltermann, L., Andersen, K. L., Johansen, H. K., Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response
Goltermann, L., Johansen, H. K., Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, p. 1667-1668 2 p.Research output: Contribution to journal › Letter › peer-review
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Methods and cells for production of volatile compounds
Pogrebnyakov, I. & Nielsen, A. T., 10 Mar 2022, IPC No. C12P 7/ 28 A I, Patent No. WO2022049125, 1 Sept 2020, Priority date 1 Sept 2020, Priority No. EP20200193767Research output: Patent
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New concepts in antimicrobial resistance in cystic fibrosis respiratory infections
Drevinek, P., Canton, R., Johansen, H. K., Hoffman, L., Coenye, T., Burgel, P. R. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 9 p., 937-945.Research output: Contribution to journal › Review › peer-review
Open AccessFile9 Downloads (Pure) -
Persistent Bacterial Infections, Antibiotic Treatment Failure, and Microbial Adaptive Evolution
La Rosa, R., Johansen, H. K. & Molin, S., 2022, In: Antibiotics. 11, 3, 8 p., 419.Research output: Contribution to journal › Journal article › Research › peer-review
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Polymicrobial infections can select against Pseudomonas aeruginosa mutators because of quorum-sensing trade-offs
Luján, A. M., Paterson, S., Hesse, E., Sommer, L. M., Marvig, R. L., Sharma, M. D., Alseth, E. O., Ciofu, O., Smania, A. M., Molin, S., Johansen, H. K. & Buckling, A., 2022, In: Nature Ecology and Evolution. 6, 7, p. 979-988 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2021
Adaptive interactions of achromobacter spp. With pseudomonas aeruginosa in cystic fibrosis chronic lung co-infection
Sandri, A., Haagensen, J. A. J., Veschetti, L., Johansen, H. K., Molin, S., Malerba, G., Signoretto, C., Boaretti, M. & Lleo, M. M., 2021, In: Pathogens. 10, 8, 978.Research output: Contribution to journal › Journal article › Research › peer-review
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A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
Backer, V., Sjöbring, U., Sonne, J., Weiss, A., Hostrup, M., Johansen, H. K., Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: Lancet Regional Health. Europe. 4, 8 p., 100084.Research output: Contribution to journal › Journal article › Research › peer-review
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Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment
Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Krogh Johansen, H., Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 10 p., 120420.Research output: Contribution to journal › Journal article › Research › peer-review
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Compensatory evolution of Pseudomonas aeruginosa’s slow growth phenotype suggests mechanisms of adaptation in cystic fibrosis
La Rosa, R., Rossi, E., Feist, A. M., Johansen, H. K. & Molin, S., Dec 2021, In: Nature Communications. 12, 1, 15 p., 3186.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of resonant electromagnetic fields on biofilm formation in pseudomonas aeruginosa
Haagensen, J. A. J., Bache, M., Giuliani, L. & Blom, N. S., 2021, In: Applied Sciences. 11, 16, 11 p., 7760.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced Eradication of Mucin-Embedded Bacterial Biofilm by Locally Delivered Antibiotics in Functionalized Microcontainers
Birk, S. E., Serioli, L., Cavallo, V., Haagensen, J. A. J., Molin, S., Nielsen, L. H., Zór, K. & Boisen, A., 2021, In: Macromolecular Bioscience. 21, 8, 10 p., 2100150.Research output: Contribution to journal › Journal article › Research › peer-review
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High-throughput dilution-based growth method enables time-resolved exo-metabolomics of Pseudomonas putida and Pseudomonas aeruginosa
Pedersen, B. H., Gurdo, N., Johansen, H. K., Molin, S., Nikel, P. I. & La Rosa, R., 2021, In: Microbial Biotechnology. 14, 5, p. 2214-2226 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile60 Downloads (Pure) -
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Rossi, E., La Rosa, R., Bartell, J. A., Marvig, R. L., Haagensen, J. A. J., Sommer, L. M., Molin, S. & Johansen, H. K., 2021, In: Nature Reviews. Microbiology. 19, p. 331-342 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Respiration Measurements of Individual Tardigrades of the Species Richtersius cf coronifer as a Function of Temperature and Salinity and Termination of Anhydrobiosis
Pedersen, B. H., Malte, H., Finster, K. & Ramløv, H., 2021, In: Astrobiology. 21, 7, p. 853-865 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ProUSER2.0 Toolbox: Genetic Parts and Highly Customizable Plasmids for Synthetic Biology in Bacillus subtilis
Falkenberg, K. B., Mol, V., De La Maza Larrea, A. S., Pogrebnyakov, I., Nørholm, M. H. H., Nielsen, A. T. & Jensen, S. I., 2021, In: ACS Synthetic Biology. 10, 12, p. 3278-3289 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile124 Downloads (Pure) -
2020
A method for studying the metabolic activity of individual tardigrades by measuring oxygen uptake using microrespirometry
Pedersen, B. H., Malte, H., Ramløv, H. & Finster, K., 2020, In: Journal of Experimental Biology. 223, jeb.233072.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic resistance: turning evolutionary principles into clinical reality
Andersson, D. I., Balaban, N. Q., Baquero, F., Courvalin, P., Glaser, P., Gophna, U., Kishony, R., Molin, S. & Tønjum, T., 2020, In: FEMS Microbiology Reviews. 44, 2, p. 171–188Research output: Contribution to journal › Journal article › Research › peer-review
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Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments
Sommer, L. M., Johansen, H. K. & Molin, S., 2020, In: Microbial Genomics. 6, 5Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile55 Downloads (Pure) -
Bacterial Cell Cultures in a Lab-on-a-Disc: A Simple and Versatile Tool for Quantification of Antibiotic Treatment Efficacy
Serioli, L., Laksafoss, T. Z., Haagensen, J. A. J., Sternberg, C., Sørensen, M. P., Molin, S., Zor, K. & Boisen, A., 2020, In: Analytical Chemistry. 92, 20, p. 13871–13879Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment
Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, H. K., 2020, In: PLOS Pathogens. 16, 12, 25 p., e1009112.Research output: Contribution to journal › Journal article › Research › peer-review
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Electrochemical detection of pyocyanin as a biomarker for pseudomonas aeruginosa: A focused review
Alatraktchi, F. A., Svendsen, W. E. & Molin, S., 2020, In: Sensors. 20, 15 p., 5218.Research output: Contribution to journal › Review › peer-review
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Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways
Gabrielaite, M., Johansen, H. K., Molin, S., Nielsen, F. C. & Marvig, R. L., 2020, In: mBio. 11, 5, 16 p., e02359-20.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile115 Downloads (Pure) -
Hypermutator Pseudomonas aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients
Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, H. K., Molin, S. & Smania, A. M., 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, 14 p., e02142-19.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving antibiotic treatment of Pseudomonas aeruginosa biofilms using N-acetylcysteine-functionalized microcontainers
Hansen, S. E., Serioli, L., Cavallo, V., Haagensen, J. A. J., Molin, S., Zor, K., Nielsen, L. H. & Boisen, A., 2020. 3 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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MEMOTE for standardized genome-scale metabolic model testing
Lieven, C., Beber, M. E., Olivier, B. G., Bergmann, F. T., Ataman, M., Babaei, P., Bartell, J. A., Blank, L. M., Chauhan, S., Correia, K., Diener, C., Dräger, A., Ebert, B. E., Edirisinghe, J. N., Faria, J. P., Feist, A. M., Fengos, G., Fleming, R. M. T., García-Jiménez, B., Hatzimanikatis, V., & 49 others, 2020, In: Nature Biotechnology. 38, 3, p. 272-276 5 p.Research output: Contribution to journal › Journal article › Communication
Open AccessFile148 Downloads (Pure) -
Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms
Birk, S. E., Haagensen, J. A. J., Johansen, H. K., Molin, S., Nielsen, L. H. & Boisen, A., 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., e1901779.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples
Alatraktchi, F. A., Dimaki, M., Støvring, N., Johansen, H. K., Molin, S. & Svendsen, W. E., 2020, In: Analytical Biochemistry. 593, 6 p., 113586.Research output: Contribution to journal › Journal article › Research › peer-review
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Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" CF patients
Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, H. K., 2020, In: The European Respiratory Journal. 57, 1, 2000512.Research output: Contribution to journal › Journal article › Research › peer-review
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Visualizing the invisible: class excursions to ignite children's enthusiasm for microbes
McGenity, T. J., Gessesse, A., Hallsworth, J. E., Garcia Cela, E., Verheecke-Vaessen, C., Wang, F., Chavarría, M., Haggblom, M. M., Molin, S., Danchin, A., Smid, E. J., Lood, C., Cockell, C. S., Whitby, C., Liu, S-J., Keller, N. P., Stein, L. Y., Bordenstein, S. R., Lal, R., Nunes, O. C., & 11 others, 2020, In: Microbial Biotechnology. 13, 4, p. 844-887 44 p.Research output: Contribution to journal › Editorial › peer-review
Open AccessFile141 Downloads (Pure) -
2019
Adapting to the airways: Metabolic requirements of Pseudomonas aeruginosa during the infection of cystic fibrosis patients
La Rosa, R., Johansen, H. K. & Molin, S., 2019, In: Metabolites. 9, 10, 234.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile97 Downloads (Pure) -
Evolutionary highways to persistent bacterial infection
Bartell, J., Sommer, L. M., Haagensen, J. A. J., Loch, A., Espinosa Portero, R., Molin, S. & Johansen, H. K., 2019, In: Nature Communications. 10, 13 p., 629.Research output: Contribution to journal › Journal article › Research › peer-review
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Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis
Burgener, E. B., Sweere, J. M., Bach, M. S., Secor, P. R., Haddock, N., Jennings, L. K., Marvig, R. L., Johansen, H. K., Rossi, E., Cao, X., Tian, L., Nedelec, L., Molin, S., Bollyky, P. L. & Milla, C. E., 2019, In: Science Translational Medicine. 11, 488, 12 p., eaau9748.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of the Crc global regulator on substrate uptake rates and the distribution of metabolic fluxes in Pseudomonas putida KT2440 growing in a complete medium
Molina, L., La Rosa, R., Nogales, J. & Rojo, F., 2019, In: Environmental Microbiology. 21, 11, p. 4446-4459Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile74 Downloads (Pure) -
Microcontainers for improved treatment of Pseudomonas aeruginosa biofilm infections
Hansen, S. E., Nielsen, L. H., Haagensen, J. A. J., Johansen, H. K., Molin, S. & Boisen, A., 2019. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Omics-based Surveillance of Pseudomonas aeruginosa Infection Identifies Clonal Persistence Despite ‘Eradication’
Bartell, J., Sommer, L., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, H. K., 2019, In: Pediatric Pulmonology. 54, p. S281-S281Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative stress under low oxygen conditions triggers hyperflagellation and motility in the Antarctic bacterium Pseudomonas extremaustralis
Venero, E. C. S., Ricardi, M. M., Gómez Lozano, M., Molin, S., Tribelli, P. M. & López, N. I., 2019, In: Extremophiles. 23, 5, p. 587-597 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs
Arndal, E., Johansen, H. K., Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, K., Høiby, N., Nielsen, K. G., Backer, V. & von Buchwald, C., 2019, In: The European Respiratory Journal. 55, 1, 1901472.Research output: Contribution to journal › Journal article › Research › peer-review
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Pseudomonas putida KT2440 metabolism undergoes sequential modifications during exponential growth in a complete medium as compounds are gradually consumed
Molina, L., La Rosa, R., Nogales, J. & Rojo, F., 2019, In: Environmental Microbiology. 21, 7, p. 2375-2390Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile289 Downloads (Pure) -
Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate
Halfon, Y., Jimenez-Fernandez, A., Rosa, R. L., Portero, R. E., Johansen, H. K., Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281Research output: Contribution to journal › Journal article › Research › peer-review
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2018
Centrifugal microfluidic platform for optical monitoring and treatment of biofilms
Serioli, L., Severini, G., Laksafoss, T. Z., Haagensen, J. A. J., Sørensen, M. P., Molin, S., Johansen, H. K., Zor, K. & Boisen, A., 2018. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Convergent Metabolic Specialization through Distinct Evolutionary Paths in Pseudomonas aeruginosa
La Rosa, R., Johansen, H. K. & Molin, S., 2018, In: mBio (Online). 9, 2, 15 p., e00269-18.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile376 Downloads (Pure)