Research output per year
Research output per year
Organisation profile
Organisation profile
The focus of our research is to understand why and how persistent bacterial infections have become an increasing health threat. We combine investigations of microbial evolution in infected patients with detailed molecular characterization of infection processes as observed in an advanced cell culture model of human airways.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Profiles
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Helle Krogh Johansen
- Department of Health Technology - Adjungeret Professor
- Novo Nordisk Foundation Center for Biosustainability - Professor, consultant, DMSc.
- Infection Microbiology
- DTU Microbes Initiative
Person: VIP
Research output
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The Pseudomonas aeruginosa sirB2 gene is a fitness determinant of anaerobic growth and its inactivation affects virulence and rugose small colony variants emergence
Baldelli, V., Carrasco Aliaga, S. J., Colque, C. A., Mazzola, F., Ravishankar, S., Johansen, H. K., Molin, S., Raffaelli, N., Paroni, M., Landini, P. & Rossi, E., 2026, In: Virulence. 17, 1, 2605800.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Downloads (Orbit) -
Characterization of microbiomes in infected Human lungs
Madsen, K., 2025, Technical University of Denmark. 234 p.Research output: Book/Report › Ph.D. thesis
Open AccessFile -
Ciprofloxacin resistance rapidly declines in nfxB defective clinical strains of Pseudomonas aeruginosa
Hernando-Amado, S., Laborda, P., La Rosa, R., Molin, S., Johansen, H. K. & Martínez, J. L., 2025, In: Nature Communications. 16, 1, 12 p., 4992.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Downloads (Orbit)
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Metabolic engineering for production of volatile biochemicals
(Escher), B. L. (PhD Student), Nielsen, A. T. (Main Supervisor) & Pogrebnyakov, I. (Supervisor)
01/12/2023 → 30/11/2026
Project: PhD
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Characterization of microbiomesin infected human lungs
Madsen, K. (PhD Student), Molin, S. (Main Supervisor), Johansen, H. K. (Supervisor), Jelsbak, L. (Examiner) & Unterweger, D. (Examiner)
01/02/2022 → 05/11/2025
Project: PhD
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Adaptation to the CF airway environment selects for specific P. aeruginosa metabotypes
Pedersen, B. H. (PhD Student), Haussler, S. (Examiner), Nikel, P. I. (Main Supervisor), La Rosa, R. (Supervisor) & de Lorenzo Prieto, V. (Examiner)
01/11/2019 → 14/06/2023
Project: PhD
Activities
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Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
La Rosa, R. (Guest lecturer)
13 Sept 2021Activity: Talks and presentations › Conference presentations
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Improving antibiotic treatment of Pseudomonas aeruginosa biofilms using N-acetylcysteine-functionalized microcontainers
Birk, S. E. (Speaker), Serioli Øland, L. (Other), Cavallo, V. (Other), Haagensen, J. A. J. (Other), Molin, S. (Other), Zor, K. (Other), Nielsen, L. H. (Other) & Boisen, A. (Other)
29 Jun 2020 → 2 Jul 2020Activity: Talks and presentations › Conference presentations
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Omics-based Surveillance of Pseudomonas aeruginosa Infection Identifies Clonal Persistence Despite ‘Eradication’
Bartell, J. (Speaker)
1 Nov 2019Activity: Talks and presentations › Conference presentations