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2019

A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

Uhlén, M., Karlsson, M. J., Zhong, W., Tebani, A., Pou, C., Mikes, J., Lakshmikanth, T., Forsström, B., Edfors, F., Odeberg, J., Mardinoglu, A., Zhang, C., von Feilitzen, K., Mulder, J., Sjöstedt, E., Hober, A., Oksvold, P., Zwahlen, M., Ponten, F., Lindskog, C. & 3 others, Sivertsson, Å., Fagerberg, L. & Brodin, P., 2019, In : Science. 366, 6472, eaax9198.

Research output: Contribution to journalJournal articleResearchpeer-review

A Systematic Investigation of the Malignant Functions and Diagnostic Potential of the Cancer Secretome

Robinson, J. L., Feizi, A., Uhlén, M. & Nielsen, J., 2019, In : Cell Reports. 26, 10, p. 2622-2635

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239 Downloads (Pure)

Chromophore pre-maturation for improved speed and sensitivity of split-GFP monitoring of protein secretion

Lundqvist, M., Thalén, N., Volk, A. L., Hansen, H. G., von Otter, E., Nygren, P-Å., Uhlén, M. & Rockberg, J., 2019, In : Scientific Reports. 9, 1, 310.

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231 Downloads (Pure)

SAMURAI (Solid-phase Assisted Mutagenesis by Uracil Restriction for Accurate Integration) for antibody affinity maturation and paratope mapping

Hu, F. J., Lundqvist, M., Uhlén, M. & Rockberg, J., 2019, In : Nucleic acids research. 47, 6, e34.

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79 Downloads (Pure)

Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics

Edfors, F., Forsström, B., Vunk, H., Kotol, D., Fredolini, C., Maddalo, G., Svensson, A. S., Boström, T., Tegel, H., Nilsson, P., Schwenk, J. M. & Uhlén, M., 2019, In : Journal of Proteome Research. 18, 7, p. 2706-2718

Research output: Contribution to journalJournal articleResearchpeer-review

Systematic Development of Sandwich Immunoassays for the Plasma Secretome

Häussler, R. S., Bendes, A., Iglesias, M. J., Sanchez-Rivera, L., Dodig-Crnković, T., Byström, S., Fredolini, C., Birgersson, E., Dale, M., Edfors, F., Fagerberg, L., Rockberg, J., Tegel, H., Uhlén, M., Qundos, U. & Schwenk, J. M., 2019, In : Proteomics. 19, 15, 19 p., 1900008.

Research output: Contribution to journalJournal articleResearchpeer-review

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185 Downloads (Pure)
2018

Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders

Hu, F. J., Volk, A-L., Persson, H., Säll, A., Borrebaeck, C., Uhlén, M. & Rockberg, J., 2018, In : New Biotechnology. 45, p. 80-88 9 p.

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327 Downloads (Pure)

Enhanced validation of antibodies for research applications

Edfors, F., Hober, A., Linderbäk, K., Maddalo, G., Azimi, A., Sivertsson, Å., Tegel, H., Hober, S., Szigyarto, C. A. K., Fagerberg, L., von Feilitzen, K., Oksvold, P., Lindskog, C., Forsström, B. & Uhlén, M., 2018, In : Nature Communications. 9, 4130.

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207 Downloads (Pure)

Surface Display of Small Affinity Proteins on Synechocystis sp Strain PCC 6803 Mediated by Fusion to the Major Type IV Pilin PilA1

Cengic, I., Uhlén, M. & Hudson, E. P., 2018, In : Journal of Bacteriology. 200, 16, 19 p., e00270-18.

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141 Downloads (Pure)

Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia

Danielsson, F., Fasterius, E., Sullivan, D., Hases, L., Sanli, K., Zhang, C., Mardinoglu, A., Al-Khalili, C., Huss, M., Uhlén, M., Williams, C. & Lundberg, E., 2018, In : OncoTarget. 9, 28, p. 19730-19744

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106 Downloads (Pure)
2017

A pathology atlas of the human cancer transcriptome

Uhlén, M., Zhang, X-C., Lee, S., Sjostedt, E., Fagerberg, L., Bidkhori, G., Benfeitas, R., Arif, M., Liu, Z., Edfors, F., Sanli, K., von Feilitzen, K., Oksvold, P., Lundberg, E., Hober, S., Nilsson, P., Mattsson, J., Schwenk, J. M., Brunnstrom, H., Glimelius, B. & 7 others, Sjoblom, T., Edqvist, P-H., Djureinovic, D., Micke, P., Lindskog, C., Mardinoglu, A. & Pontén, F., 2017, In : Science. 357, 6352, p. 660-+

Research output: Contribution to journalJournal articleResearchpeer-review

Droplet size influences division of mammalian cell factories in droplet microfluidic cultivation: Miniaturization

Periyannan Rajeswari, P. K., Joensson, H. N. & Svahn, H. A., 2017, In : Electrophoresis. 38, 2, p. 305–310 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Human protein secretory pathway genes are expressed in a tissue-specific pattern to match processing demands of the secretome

Feizi, A., Gatto, F., Uhlén, M. & Nielsen, J., 2017, In : n p j Systems Biology and Applications. 3, 1, 9 p., 22.

Research output: Contribution to journalJournal articleResearchpeer-review

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234 Downloads (Pure)

Machine learning in computational biology to accelerate high-throughput protein expression

Sastry, A., Monk, J. M., Tegel, H., Uhlén, M., Palsson, B., Rockberg, J. & Brunk, E., 2017, In : Bioinformatics. 33, 16, p. 2487-2495

Research output: Contribution to journalJournal articleResearchpeer-review

The human cell atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P., Carninci, P., Clatworthy, M., Clevers, H., Deplancke, B., Dunham, I., Eberwine, J., Eils, R., Enard, W., Farmer, A., Fugger, L., Göttgens, B., Hacohen, N. & 31 others, Haniffa, M., Hemberg, M., Kim, S., Klenerman, P., Kriegstein, A., Lein, E., Linnarsson, S., Lundberg, E., Lundeberg, J., Majumder, P., Marioni, J. C., Merad, M., Mhlanga, M., Nawijn, M., Netea, M., Nolan, G., Pe’er, D., Phillipakis, A., Ponting, C. P., Quake, S., Reik, W., Rozenblatt-Rosen, O., Sanes, J., Satija, R., Schumacher, T. N., Shalek, A., Shapiro, E., Sharma, P., Shin, J. W., Uhlén, M. & Human Cell Atlas Meeting Participants, 2017, In : eLife. 6, 30 p., e27041.

Research output: Contribution to journalJournal articleResearchpeer-review

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486 Downloads (Pure)
2016

Gene-specific correlation of RNA and protein levels in human cells and tissues

Edfors, F., Danielsson, F., Hallström, B. M., Käll, L., Lundberg, E., Ponten, F., Forsström, B. & Uhlén, M., 2016, In : Molecular Systems Biology. 12, 10, 10 p., 883.

Research output: Contribution to journalJournal articleResearchpeer-review

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244 Downloads (Pure)

Stratification of responders towards eculizumab using a structural epitope mapping strategy

Volk, A-L., Hu, F. J., Berglund, M. M., Nordling, E., Strömberg, P., Uhlén, M. & Rockberg, J., 2016, In : Scientific Reports. 6, 10 p., 31365.

Research output: Contribution to journalJournal articleResearchpeer-review

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295 Downloads (Pure)
2015

Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production

Anfelt, J., Kaczmarzyk, D., Shabestary, K., Renberg, B., Rockberg, J., Nielsen, J., Uhlén, M. & Hudson, E. P., 2015, In : Microbial Cell Factories. 14, 167, 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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240 Downloads (Pure)

Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling

Ghaffari, P., Mardinoglu, A., Asplund, A., Shoaie, S., Kampf, C., Uhlén, M. & Nielsen, J., 2015, In : Scientific Reports. 5, 10 p., 8183.

Research output: Contribution to journalJournal articleResearchpeer-review

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228 Downloads (Pure)

Metabolite profiling of microfluidic cell culture conditions for droplet based screening

Björk, S. M., Sjoström, S. L., Svahn, H. A. & Jönsson, H., 2015, In : Biomicrofluidics. 9, 4, 10 p., 044128.

Research output: Contribution to journalJournal articleResearchpeer-review

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast

Huang, M., Bai, Y., Sjostrom, S. L., Hallström, B. M., Liu, Z., Petranovic, D., Uhlén, M., Joensson, H. N., Svahn, H. A. & Nielsen, J., 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. E4689-E4696 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Overexpression of functional human oxidosqualene cyclase in Escherichia coli

Kürten, C., Uhlén, M. & Syrén, P-O., 2015, In : Protein Expression and Purification. 115, p. 46-53 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Single-cell screening of photosynthetic growth and lactate production by cyanobacteria

Hammar, P., Angermayr, S. A., Sjostrom, S. L., van der Meer, J., Hellingwerf, K. J., Hudson, E. P. & Jönsson, H., 2015, In : Biotechnology for Biofuels. 8, 1, 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

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262 Downloads (Pure)

Solid-phase cloning for high-throughput assembly of single and multiple DNA parts

Lundqvist, M., Edfors, F., Sivertsson, Å., Hallström, B. M., Hudson, E. P., Tegel, H., Holmberg, A., Uhlén, M. & Rockberg, J., 2015, In : Nucleic acids research. 43, 7, 11 p., 20e49-e49.

Research output: Contribution to journalJournal articleResearchpeer-review

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277 Downloads (Pure)

The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Lindskog, C., Linne, J., Fagerberg, L., Hallstrom, B. M., Sundberg, C. J., Lindholm, M., Huss, M., Kampf, C., Choi, H., Liem, D. A., Ping, P., Väremo, L., Mardinoglu, A., Nielsen, J., Larsson, E., Ponten, F. & Uhlén, M., 2015, In : BMC Genomics. 16, 16 p., 475.

Research output: Contribution to journalJournal articleResearchpeer-review

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281 Downloads (Pure)

Tissue-based map of the human proteome

Uhlén, M., Fagerberg, L., Hallström, B. M., Lindskog, C., Oksvold, P., Mardinoglu, A., Sivertsson, Å., Kampf, C., Sjöstedt, E., Asplund, A., Olsson, I., Edlund, K., Lundberg, E., Navani, S., Szigyarto, C. A-K., Odeberg, J., Djureinovic, D., Takanen, J. O., Hober, S., Alm, T. & 16 others, Edqvist, P-H., Berling, H., Tegel, H., Mulder, J., Rockberg, J., Nilsson, P., Schwenk, J. M., Hamsten, M., von Feilitzen, K., Forsberg, M., Persson, L., Johansson, F., Zwahlen, M., von Heijne, G., Nielsen, J. & Pontén, F., 2015, In : Science (New York, N.Y.). 347, 6220, p. 394- 9 p., 1260419.

Research output: Contribution to journalJournal articleResearchpeer-review

Versatile microscale screening platform for improving recombinant protein productivity in Chinese hamster ovary cells

Hansen, H. G., Nilsson, C. N., Lund, A. M., Kol, S., Grav, L. M., Lundqvist, M., Rockberg, J., Min Lee, G., Andersen, M. R. & Kildegaard, H. F., 2015, In : Scientific Reports. 5, 12 p., 18016 .

Research output: Contribution to journalJournal articleResearchpeer-review

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315 Downloads (Pure)
2014

Improved Production of a Heterologous Amylase in Saccharomyces cerevisiae by Inverse Metabolic Engineering

Liu, Z., Liu, L., Osterlund, T., Hou, J., Huang, M., Fagerberg, L., Petranovic, D., Uhlén, M. & Nielsen, J., 2014, In : APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 80, 17, p. 5542-5550 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2012

Automated Solid-Phase Subcloning Based on Beads Brought into Proximity by Magnetic Force

Hudson, E. P., Nikoshkov, A., Uhlén, M. & Rockberg, J., 2012, In : P L o S One. 7, 5, p. -

Research output: Contribution to journalJournal articleResearchpeer-review

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Scheffersomyces stipitis: a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae

Papini, M., Nookaew, I., Uhlén, M. & Nielsen, J., 2012, In : Microbial Cell Factories. 11

Research output: Contribution to journalJournal articleResearchpeer-review

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