Organisation profile

Organisation profile

The Enzyme Engineering and Structural Biology group develops and utilizes enzymology to tackle the biodiversity crisis.

Using structural biology and protein chemistry as our primary tools, we strive to take a modern approach to these well-established disciplines, with multidimensional experimental setup and increased throughput. We are particularly interested in enzymatic glycosylation of natural products, such as aromas, fragrances, dyes, and pharmaceuticals, as a tool to control their solubility, volatility, stability, compartmentalization, and toxicity. For this, we focus on plant enzymes of the glycosyltransferase class. Our primary techniques are X-ray crystallography, rational design, machine learning, and HPLC. We work to elucidate glycosyltransferase structure-function relationships governing specificity, turn-over rate, and stability to ultimately develop low impact and industrially relevant enzymatic processes.

If you are interested in joining us, please don’t hesitate to reach out.

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 7 - Affordable and Clean Energy
  • SDG 13 - Climate Action
  • SDG 14 - Life Below Water


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Collaborations and top research areas from the last five years

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