Department of Biotechnology and Biomedicine

  • Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output 2011 2020

2018
51 Downloads (Pure)

New Insights into the Potential of Endogenous Redox Systems in Wheat Bread Dough

Navrot, N., Buhl Holstborg, R., Hägglund, P., Povlsen, I. L. & Svensson, B., 2018, In : Antioxidants. 7, 12, 190.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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168 Downloads (Pure)

New Penicillium and Talaromyces species from honey, pollen and nests of stingless bees

Barbosa, R. N., Bezerra, J. D. P., Souza-Motta, C. M., Frisvad, J. C., Samson, R. A., Oliveira, N. T. & Houbraken, J., 2018, In : Antonie van Leeuwenhoek: Journal of Microbiology. 111, 10, p. 1883-1912

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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196 Downloads (Pure)

Novel Enzyme Actions for Sulphated Galactofucan Depolymerisation and a New Engineering Strategy for Molecular Stabilisation of Fucoidan Degrading Enzymes

Cao, H. T. T., Mikkelsen, M. D., Lezyk, M. J., Bui, L. M., Tran, V. T. T., Silchenko, A. S., Kusaykin, M. I., Pham, T. D., Truong, B. H., Holck, J. & Meyer, A. S., 2018, In : Marine Drugs. 16, 11, 422.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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219 Downloads (Pure)

Novofumigatonin biosynthesis involves a non-heme iron-dependent endoperoxide isomerase for orthoester formation

Matsuda, Y., Bai, T., Phippen, C. B. W., Nødvig, C. S., Kjærbølling, I., Vesth, T. C., Andersen, M. R., Mortensen, U. H., Gotfredsen, C. H., Abe, I. & Larsen, T. O., 2018, In : Nature Communications. 9, 1, 10 p., 2587 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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141 Downloads (Pure)

Occurrence of Aspergillus section Flavi and aflatoxins in Brazilian rice: From field to market

Katsurayama, A. M., Martins, L. M., Iamanaka, B. T., Fungaro, M. H. P., da Silva, J. J., Frisvad, J. C., Pitt, J. I. & Taniwaki, M. H., 2018, In : International Journal of Food Microbiology. 266, p. 213-221 31 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research

Overgaard, N. H., Fan, T. M., Schachtschneider, K. M., Principe, D. R., Schook, L. B. & Jungersen, G., 2018, In : I L A R Journal. 59, 3, p. 247-262 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

328 Downloads (Pure)

On the biosynthetic origin of carminic acid

Rasmussen, S. A., Kongstad, K. T., Khorsand-Jamal, P., Kannangara, R. M., Nafisi, M., Van Dam, A., Bennedsen, M., Madsen, B., Okkels, F., Gotfredsen, C. H., Stærk, D., Thrane, U., Mortensen, U. H., Larsen, T. O. & Frandsen, R. J. N., 2018, In : Insect Biochemistry and Molecular Biology. 96, p. 51-61 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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P-192 - Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

Degendorfer, G., Lorentzen, L. G., Chuang, C. Y., Mariotti, M., Hammer, A., Hoefler, G., Hägglund, P., Malle, E., Wise, S. & Davies, M. J., 2018, In : Free Radical Biology & Medicine. 120, Suppl. 1, p. 102-103

Research output: Contribution to journalConference abstract in journalResearchpeer-review

453 Downloads (Pure)

Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa

Alatraktchi, F. A., Noori, J. S., Tanev, G. P., Mortensen, J., Dimaki, M., Johansen, H. K., Madsen, J., Molin, S. & Svendsen, W. E., 2018, In : P L o S One. 13, 3, 9 p., e0194157.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Parts Characterization for Tunable Protein Expression

Klausen, M. S. & Sommer, M. O. A., 2018, Synthetic Metabolic Pathways. Vol. 1671. p. 3-14 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Patterns of co-occurrence of congenital heart defects follows distinct patterns

Ellesoe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, V. E., Brunak, S. & Larsen, L. A., 2018, Proceedings of the 50th European-Society-of-Human-Genetics (ESHG) Conference. Suppl. 1 ed. Nature Publishing Group, Vol. 26. p. 106-106 1 p. C21.6. (European journal of human genetics; No. Suppl. 1, Vol. 26).

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Personalized mathematical model of endotoxin-induced inflammatory responses in young men and associated changes in heart rate variability

Brady, R., Frank-Ito, D. O., Tran, H. T., Janum, S., Møller, K., Brix, S., Ottesen, J. T., Mehlsen, J. & Olufsen, M. S., 1 Jan 2018, In : Mathematical Modelling of Natural Phenomena. 13, 5, 20 p., 42.

Research output: Contribution to journalJournal articleResearchpeer-review

126 Downloads (Pure)

Pharmacometabolomics Informs About Pharmacokinetic Profile of Methylphenidate

Kaddurah-Daouk, R., Hankemeier, T., Scholl, E. H., Baillie, R., Harms, A., Stage, C., Dalhoff, K. P., Jűrgens, G., Taboureau, O., Nzabonimpa, G. S., Motsinger-Reif, A. A., Thomsen, R., Linnet, K. & Rasmussen, H. B., 2018, In : C P T: Pharmacometrics & Systems Pharmacology. 7, 8, p. 525-533

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Phylogenetic distribution of roseobacticides in the Roseobacter group and their effect on microalgae

Sonnenschein, E. C., Phippen, C. B. W., Bentzon-Tilia, M., Rasmussen, S. A., Nielsen, K. F. & Gram, L., 2018, In : Environmental Microbiology Reports. 10, 3, p. 383-393

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Physcomitrella patens, a versatile synthetic biology chassis

Reski, R., Bae, H. & Simonsen, H. T., 2018, In : Plant Cell Reports. 37, 10, p. 1409-1417

Research output: Contribution to journalJournal articleResearchpeer-review

15 Downloads (Pure)

Physiology and metabolism of Yarrowia lipolytica for the utilization of alternative carbon substrates

Lubuta, P. J. K., 2018, Technical University of Denmark. 139 p.

Research output: Book/ReportPh.D. thesisResearch

Open Access
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Pigs are useful for the molecular study of bone inflammation and regeneration in humans

Lüthje, F. L., Skovgaard, K., Jensen, H. E. & Kruse Jensen, L., 2018, In : Laboratory Animals. 52, 6, p. 630-640

Research output: Contribution to journalJournal articleResearchpeer-review

152 Downloads (Pure)

Plant Polyphenols Stimulate Adhesion to Intestinal Mucosa and Induce Proteome Changes in the Probiotic Lactobacillus acidophilus NCFM

Celebioglu, H. U., Delsoglio, M., Brix, S., Pessione, E. & Svensson, B., 2018, In : Molecular Nutrition & Food Research. 62, 4, 1700638.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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146 Downloads (Pure)

Plasma ceramide levels are altered in low and normal birth weight men in response to short-term high-fat overfeeding

Ribel-Madsen, A., Ribel-Madsen, R., Nielsen, K. F., Pedersen, S. B., A. Vaag, A. & Brøns, C., 2018, In : Scientific Reports. 8, 11 p., 3452 .

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Plasma membrane proteome analysis identifies a role of barley membrane steroid binding protein in root architecture response to salinity: Barley plasma membrane proteins under salinity

Witzel, K., Matros, A., Moller, A. L. B., Ramireddy, E., Finnie, C., Peukert, M., Rutten, T., Herzog, A., Kunze, G., Melzer, M., Kaspar-Schoenefeld, S., Schmuelling, T., Svensson, B. & Mock, H-P., 2018, In : Plant, Cell and Environment. 41, 6, p. 1311-1330 20 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Polyphasic data support the splitting of Aspergillus candidus into two species; proposal of Aspergillus dobrogensis sp. nov.

Hubka, V., Nováková, A., Jurjević, Ž., Sklenář, F., Frisvad, J. C., Houbraken, J., Arendrup, M. C., Jørgensen, K. M., Siqueira, J. P. Z., Gené, J. & Kolarík, M., 2018, In : International Journal of Systematic and Evolutionary Microbiology. 68, p. 995-1011

Research output: Contribution to journalJournal articleResearchpeer-review

Prenatal Intra-Amniotic Endotoxin Induces Fetal Gut and Lung Immune Responses and Postnatal Systemic Inflammation in Preterm Pigs

Nguyen, D. N., Thymann, T., Goericke-Pesch, S. K., Ren, S., Wei, W., Skovgaard, K., Damborg, P., Brunse, A., van Gorp, C., Kramer, B. W., Wolfs, T. G. & Sangild, P. T., 2018, In : American Journal of Pathology. 188, 11, p. 2629-2643

Research output: Contribution to journalJournal articleResearchpeer-review

789 Downloads (Pure)

Pros and cons of different therapeutic antibody formats for recombinant antivenom development

Laustsen, A. H., Gutiérrez, J. M., Knudsen, C., Johansen, K. H., Bermúdez-Méndez, E., Cerni, F. A., Jürgensen, J. A., Ledsgaard, L., Martos Esteban, A., Øhlenschlæger, M., Pus, U., Andersen, M. R., Lomonte, B., Engmark, M. & Pucca, M. B., 2018, In : Toxicon. 146, p. 151-175

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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192 Downloads (Pure)

Pseudoalteromonas haloplanktis TAC125 produces 4-hydroxybenzoic acid that induces pyroptosis in human A459 lung adenocarcinoma cells

Sannino, F., Sansone, C., Galasso, C., Kildgaard, S., Tedesco, P., Fani, R., Marino, G., de Pascale, D., Ianora, A., Parrilli, E., Larsen, T. O., Romano, G. & Tutino, M. L., 2018, In : Scientific Reports. 8, 1, 10 p., 1190.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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144 Downloads (Pure)

Publisher Correction: In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies

Laustsen, A. H., Karatt-Vellatt, A., Masters, E. W., Arias, A. S., Pus, U., Knudsen, C., Oscoz, S., Slavny, P., Griffiths, D. T., Luther, A. M., Leah, R. A., Lindholm, M., Lomonte, B., Gutiérrez, J. M. & McCafferty, J., 2018, In : Nature Communications. 9, 1, 1 p., 4957 .

Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

Open Access
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140 Downloads (Pure)

Quantitative immunoassay for mink immunoglobulin in serum and milk

Mathiesen, R., Chriél, M., Struve, T. & Heegaard, P. M. H., 2018, In : Acta Veterinaria Scandinavica. 60, 1, 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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1 Downloads (Pure)

Rate-limiting step and substrate accessibility of cellobiohydrolase Cel6A from Trichoderma reesei

Christensen, S. J., Kari, J., Badino, S. F., Borch, K. & Westh, P., 2018, In : FEBS Journal. 285, 23, p. 4482-4493

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Real-time measurement of laccase catalyzed formation of radicals in lignin by electron paramagnetic resonance spectroscopy

Munk, L., Andersen, M. L. & Meyer, A. S., 2018, Proceedings of the 255th ACS National Meeting & Exposition. American Chemical Society, Vol. 255. 1 p. 117. (American Chemical Society. Abstracts of Papers (at the National Meeting)).

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

145 Downloads (Pure)

Recent Advances in Next Generation Snakebite Antivenoms

Knudsen, C. & Laustsen, A. H., 2018, In : Tropical Medicine and Infectious Disease. 3, 2, 13 p., 42.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
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64 Downloads (Pure)

Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses

Ugolini, M., Gerhard, J., Burkert, S., Jensen, K. J., Georg, P., Ebner, F., Volkers, S. M., Thada, S., Dietert, K., Bauer, L., Schäfer, A., Helbig, E. T., Opitz, B., Kurth, F., Sur, S., Dittrich, N., Gaddam, S., Conrad, M. L., Benn, C. S., Blohm, U. & 9 others, Gruber, A. D., Hutloff, A., Hartmann, S., Boekschoten, M. V., Müller, M., Jungersen, G., Schumann, R. R., Suttorp, N. & Sander, L. E., 2018, In : Nature Immunology. 19, 4, p. 386-396

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Recombinant antivenom against the venom of Dendroaspis polylepis

Knudsen, C., Karatt-Vellat, A., Andersen, M. R., Harrison, R., Casewell, N., Kilstrup, M., McCafferty, J. & Laustsen, A. H., 2018, In : Toxicon. 158, Suppl. 1, p. S43-S43 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

235 Downloads (Pure)

Reconstructing Dynamic Promoter Activity Profiles from Reporter Gene Data

Kannan, S., Sams, T., Maury, J. & Workman, C. T., 2018, In : A C S Synthetic Biology.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Reconstruction of 24 Penicillium genome-scale metabolic models shows diversity based on their secondary metabolism

Prigent, S., Nielsen, J. C., Frisvad, J. C. & Nielsen, J., 2018, In : Biotechnology and Bioengineering. 115, 10, p. 2604-2612

Research output: Contribution to journalJournal articleResearchpeer-review

75 Downloads (Pure)

Rev-clip, a new approach to identify proteins interacting with rna

Muller, S. & Workman, C., 2018, IPC No. C12N15/10, Patent No. EP3296397 , 21 Mar 2018, Priority date 20 Sep 2016, Priority No. EP20160189688

Research output: Patent

Open Access
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84 Downloads (Pure)

Revealing the Dimeric Crystal and Solution Structure of β-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer–Dimer Equilibrium

Khan, S., Ipsen, R., Almdal, K., Svensson, B. & Harris, P., 2018, In : Biomacromolecules. 19, p. 2905-2912

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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236 Downloads (Pure)

Safety of the fungal workhorses of industrial biotechnology: update on the mycotoxin and secondary metabolite potential of Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei

Frisvad, J. C., Møller, L. L. H., Larsen, T. O., Kumar, R. & Arnau, J., 2018, In : Applied Microbiology and Biotechnology. 102, 22, p. 9481-9515

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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133 Downloads (Pure)

Seaweed bioethanol production: A process selection review on hydrolysis and fermentation

Offei, F., Mensah, M., Thygesen, A. & Kemausuor, F., 2018, In : Fermentation. 4, 4, 18 p., 99.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
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Secondary metabolite production by cereal-associated penicillia during cultivation on cereal grains

Hallas-Møller, M., Nielsen, K. F. & Frisvad, J. C., 2018, In : Applied Microbiology and Biotechnology. 102, 19, p. 8477-8491

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
180 Downloads (Pure)

Send more data: a systematic review of mathematical models of antimicrobial resistance

Birkegård, A. C., Halasa, T., Toft, N., Folkesson, A. & Græsbøll, K., 2018, In : Antimicrobial Resistance and Infection Control. 7, 1, 12 p., 117.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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142 Downloads (Pure)

Serine/Threonine protein kinases from bacteria, archaea and eukarya share a common evolutionary origin deeply rooted in the tree of life

Stancik, I. A., Šestak, M. S., Ji, B., Axelson-Fisk, M., Franjevic, D., Jers, C., Domazet-Lošo, T. & Mijakovic, I., 2018, In : Journal of Molecular Biology. 430, 1, p. 27-32

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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102 Downloads (Pure)

Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders

Jensen, C., Nielsen, S. H., Mortensen, J. H., Kjeldsen, J., Klinge, L. G., Krag, A., Harling, H., Jørgensen, L. N., Karsdal, M. A. & Willumsen, N., 2018, In : Cancer Medicine. 7, 9, p. 4619-4626

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Skimmelsvampe i danske bygninger

Thrane, U. & Andersen, B., 2018, In : Svampe. 78, p. 26-35 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

72 Downloads (Pure)

Snake Venomics Display: An online toolbox for visualization of snake venomics data

Dam, S. H., Friis, R. U. W., Petersen, S. D., Martos-Esteban, A. & Laustsen, A. H., 2018, In : Toxicon. 152, p. 60-64

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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57 Downloads (Pure)

Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals

Leinisch, F., Mariotti, M., Hägglund, P. & Davies, M. J., 2018, In : Free Radical Biology and Medicine. 126, p. 73-86

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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49 Downloads (Pure)

Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi

Klas, K. R., Kato, H., Frisvad, J. C., Yu, F., Newmister, S. A., Fraley, A. E., Sherman, D. H., Tsukamoto, S. & Williams, R. M., 2018, In : Natural Product Reports. 35, 6, p. 532-558 27 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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203 Downloads (Pure)

Structure dependent antioxidant capacity of phlorotannins from Icelandic Fucus vesiculosus by UHPLC-DAD-ECD-QTOFMS

Hermund, D. B., Plaza, M., Turner, C., Jonsdottir, R., Kristinsson, H. G., Jacobsen, C. & Nielsen, K. F., 2018, In : Food Chemistry. 240, p. 904-909 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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164 Downloads (Pure)

Subtyping of Swine Influenza Viruses Using a High-Throughput Real-Time PCR Platform

Goecke, N. B., Krog, J. S., Hjulsager, C. K., Skovgaard, K., Harder, T. C., Breum, S. Ø. & Larsen, L. E., 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 12 p., 165.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Suppression of active, but not total MMP-3, is associated with treatment response in a phase III clinical study of rheumatoid arthritis

Siebuhr, A. S., Kjelgaard-Petersen, C. F., Sun, S., Byrjalsen, I., Christiansen, C., Karsdal, M. A. & Bay-Jensen, A., 2018, In : Clinical and Experimental Rheumatology. 36, 1, p. 94-101 CER10190.

Research output: Contribution to journalJournal articleResearchpeer-review

339 Downloads (Pure)
Open Access
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141 Downloads (Pure)

Targeting the Mincle and TLR3 receptor using the dual agonist cationic adjuvant formulation 9 (CAF09) induces humoral and polyfunctional memory T cell responses in calves

Thakur, A., Andrea, A., Mikkelsen, H., Woodworth, J. S., Andersen, P., Jungersen, G., Aagaard, C. & Ho, P. L. (ed.), 2018, In : P L o S One. 13, 7, 19 p., e0201253.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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