Department of Biotechnology and Biomedicine

  • Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output 2011 2020

2019
114 Downloads (Pure)

Global view of the RAF-MEK-ERK module and its immediate downstream effectors

Santini, C. C., Longden, J., Schoof, E. M., Simpson, C. D., Jeschke, G. R., Creixell, P., Kim, J., Wu, X., Turk, B. E., Rosen, N., Poulikakos, P. I. & Linding, R., 2019, In : Scientific Reports. 9, 1, 11 p., 10865.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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157 Downloads (Pure)

Glycan Utilization Strategy of the Butyrate Producing Gut Symbiont Roseburia intestinalis

Leth, M. L., 2019, Kgs. Lyngby, Denmark: Technical University of Denmark. 189 p.

Research output: Book/ReportPh.D. thesisResearch

Open Access
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Glycerol metabolism of Pichia pastoris (Komagataella spp.) characterised by 13C-based metabolic flux analysis

Tomàs-Gamisans, M., Ødum, A. S. R., Workman, M., Ferrer, P. & Albiol, J., 2019, In : New Biotechnology. 50, p. 52-59 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

47 Downloads (Pure)
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Green seaweeds (Ulva fasciata sp.) as nitrogen source for fungal cellulase production

Bentil, J. A., Thygesen, A., Lange, L., Mensah, M. & Meyer, A. S., 2019, In : World Journal of Microbiology and Biotechnology. 35, 6, 8 p., 82.

Research output: Contribution to journalJournal articleResearchpeer-review

Guiding antivenom development through linear visualization of venomics data

Dam, S. H., Friis, R. U. W. & Laustsen, A. H., 2019, In : Toxicon. 158, Suppl. 1, p. S44-S44

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Harnessing human monoclonal antibodies for neutralisation of dendrotoxins in a murine model

Knudsen, C., Arias, A. S., Lomonte, B., Mar a Guti rrez, J., Puš, R., Oscoz, S., Masters, E. W., Luther, A. M., Griffiths, D. T., Olesen, M. L., Leah, R. A., Slavny, P., Karatt-Vellatt, A., McCafferty, J. & Laustsen, A. H., 2019, In : Toxicon. 159, Supp. 1, p. S14

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Harnessing phage display technology for discovery of human IgGs targeting clinically relevant toxins from the venom of the Central American coral snake (Micrurus nigrocinctus)

Méndez, E. B., Fernández, J., Lomonte, B., Gutiérrez, J. M. & Laustsen, A. H., 2019, In : Toxicon. 158, Suppl. 1, p. S45-s45 1 p., 150.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Harnessing phage display technology for generating fully human IgG antibodies that neutralise elapid neurotoxins

Karatt-Vellatt, A., Laustsen, A. H., Masters, E. W., Oscoz, S., Pus, U., Knudsen, C., Slavny, P., Luther, A. M., Leah, R. A., Grifiths, D. T., Olesen, M. L., Lomonte, B., Gutiérrez, J. M. & McCafferty, J., 2019, In : Toxicon. 158, Suppl. 1, p. s18-s18 1 p., 59.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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178 Downloads (Pure)

Heavy metal exposure causes changes in the metabolic health-associated gut microbiome and metabolites

Li, X., Brejnrod, A. D., Ernst, M., Rykær, M., Herschend, J., Olsen, N. M. C., Dorrestein, P. C., Rensing, C. & Sørensen, S. J., 2019, In : Environment International. 126, p. 454-467 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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28 Downloads (Pure)

High levels of MMP-cleaved mimecan is associated to carotid plaque stability and less future cardiovascular events

Goncalves, I., Tengryd, C., Nielsen, S. H., Genovese, F., Bengtsson, E., Karsdal, M., Leeming, D. J., Nilsson, J. & Edsfeldt, A., 2019, In : European Heart Journal. 40, Suppl. 1, 1 p., 3046.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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31 Downloads (Pure)

History of envenoming therapy and current perspectives

Pucca, M. B., Cerni, F. A., Janke, R., Bermúdez-Méndez, E., Ledsgaard, L., Barbosa, J. E. & Laustsen, A. H., 2019, In : Frontiers in Immunology. 10, 13 p., 1598.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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How can monoclonal antibodies be harnessed against neglected tropical diseases and other infectious diseases?

Laustsen, A. H., 2019, In : Expert Opinion on Drug Discovery. 14, 11, p. 1-10 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

197 Downloads (Pure)

Identification and characterization of GH11 xylanase and GH43 xylosidase from the chytridiomycetous fungus, Rhizophlyctis rosea

Huang, Y., Zheng, X., Pilgaard, B., Holck, J., Muschiol, J., Li, S. & Lange, L., 2019, In : Applied Microbiology and Biotechnology. 103, 2, p. 777-791 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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48 Downloads (Pure)

Identification and optimization of PrsA in Bacillus subtilis for improved yield of amylase

Quesada Ganuza, A., Antelo-Varela, M., Mouritzen, J. C., Bartel, J., Becher, D., Gjermansen, M., Hallin, P. F., Appel, K. F., Kilstrup, M., Rasmussen, M. D. & Nielsen, A. K., 2019, In : Microbial Cell Factories. 18, 1, 16 p., 158.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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16 Downloads (Pure)

Immune Mediator Levels in the Upper Airways Predict Response to Azithromycin for Episodes with Asthma-like Symptoms in Young Children

Carlsson, C. J., Rasmussen, M. A., Brix, S., Wang, N., Stokholm, J., Chawes, B., Bonnelykke, K. & Bisgaard, H. F., 2019, In : Pediatric Pulmonology. 54, S1, p. S75-S76 2 p., A-27.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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187 Downloads (Pure)

Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children

Zhong, H., Penders, J., Shi, Z., Ren, H., Cai, K., Fang, C., Ding, Q., Thijs, C., Blaak, E. E., Stehouwer, C. D. A., Xu, X., Yang, H., Wang, J., Wang, J., Jonkers, D. M. A. E., Masclee, A. A. M., Brix, S., Li, J., Arts, I. C. W. & Kristiansen, K., 2019, In : Microbiome. 7, 14 p., 2.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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55 Downloads (Pure)

Impact of Phaeobacter inhibens on marine eukaryote-associated microbial communities

Dittmann, K. K., Sonnenschein, E. C., Egan, S., Gram, L. & Bentzon-Tilia, M., 2019, In : Environmental Microbiology Reports. 11, 3, p. 401-413 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Improving the production of cofactor-containing proteins: production of human hemoglobin in yeast

Ishchuk, O. P., Martinez Ruiz, J. L. & Petranovic, D., 2019, Recombinant Protein Production in Yeast . Springer, p. 243-264 22 p. (Methods in Molecular Biology, Vol. 1923).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Increased trans-glycosylation activity of hexosaminidases for synthesis of human milk oligosaccharides

Muschiol, J., Binti Jamek, S., Holck, J., Zeuner, B., Busk, P. K., Lange, L., Mikkelsen, J. D. & Meyer, A. S., 2019, p. 153-153. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

3 Downloads (Pure)

In Depth Physiological Characterization Reveals a Novel Survival Strategy for the Yeast Debaryomyces hansenii at Very High Salinity, Confirming its Halophilic Behavior.

Navarrete Román, C., Frost, A. T., Ramos-Moreno, L. & Martinez Ruiz, J. L., 2019, p. 160-160. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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45 Downloads (Pure)

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

Thorsen, J., Rasmussen, M. A., Waage, J., Mortensen, M., Brejnrod, A., Bønnelykke, K., Chawes, B. L., Brix, S., Sørensen, S. J., Stokholm, J. & Bisgaard, H. F., 2019, In : Nature Communications. 10, 1, 8 p., 5001.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Influence of chlorides and phosphates on the antiadhesive, antibacterial, and electrochemical properties of an electroplated copper-silver alloy

Ciacotich, N., Kilstrup, M., Møller, P. & Gram, L., 2019, In : Biointerphases. 14, 2, 11 p., 021005.

Research output: Contribution to journalJournal articleResearchpeer-review

24 Downloads (Pure)

In planta and in silico characterization of five sesquiterpene synthases from Vitis vinifera (cv. Shiraz) berries

Dueholm, B., Drew, D. P., Sweetman, C. & Simonsen, H. T., 2019, In : Planta. 249, 1, p. 59-70 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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28 Downloads (Pure)

Insights into Heterologous Biosynthesis of Arteannuin B and Artemisinin in Physcomitrella patens

Ikram, N. K. K., Kashkooli, A. B., Peramuna, A. V., Krol, A. R. V. D., Bouwmeester, H. & Simonsen, H. T., 2019, In : Molecules. 24, 21, 13 p., 3822.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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22 Downloads (Pure)

In Situ Monitoring of the Antibacterial Activity of a Copper–Silver Alloy Using Confocal Laser Scanning Microscopy and pH Microsensors

Ciacotich, N., Kragh, K. N., Lichtenberg, M., Tesdorpf, J. E., Bjarnsholt, T. & Gram, L., 2019, In : Global Challenges. 3, 11, 9 p., 1900044.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Interaction between feruloylated arabinoxylan and nanocellulose: Effect on bulk rheological and material properties

Perzon, A., Muschiol, J., Meyer, A. S., Munk, L., Liu, M., Holland, C., Jørgensen, B. & Ulvskov, P., 2019, In : American Chemical Society. Abstracts of Papers (at the National Meeting). 257, 255.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

59 Downloads (Pure)
Open Access
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182 Downloads (Pure)

Interplay between food and gut microbiota in health and disease

Danneskiold-Samsøe, N. B., de Freitas Queiroz Barros, H. D., Santos, R., Bicas, J. L., Cazarin, C. B. B., Madsen, L., Kristiansen, K., Pastore, G. M., Brix, S. & Junior, M. R. M., 2019, In : Food Research International. 115, p. 23-31

Research output: Contribution to journalReviewResearchpeer-review

Open Access
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INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

Jungersen, G. & Piedrahita, J., 2019, In : I L A R Journal. 59, 3, p. 209-210

Research output: Contribution to journalJournal articleCommunication

33 Downloads (Pure)

Investigating the Influence of Glycerol on the Utilization of Glucose in Yarrowia lipolytica Using RNA-Seq-Based Transcriptomics

Lubuta, P. J. K., Workman, M., Kerkhoven, E. J. & Workman, C. T., 2019, In : G3: Genes, Genomes, Genetics (Bethesda). 9, 12, p. 4059-4071 48 p., g3.400469.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Isolation of Methyl Troposulfenin from Phaeobacter inhibens

Phippen, C. B. W., Jørgensen, C. M., Bentzon-Tilia, M., Gotfredsen, C. H., Larsen, T. O., Gram, L. & Sonnenschein, E. C., 2019, In : Journal of Natural Products. 82, 5, p. 1387-1390 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Laccase activity measurement by FTIR spectral fingerprinting

Perna, V., Baum, A., Ernst, H. A., Agger, J. W. & Meyer, A. S., 2019, In : Enzyme and Microbial Technology. 122, p. 64-73 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

38 Downloads (Pure)
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Laccase Induced Lignin Radical Formation Kinetics Evaluated by Electron Paramagnetic Resonance Spectroscopy

Perna, V., Agger, J. W., Andersen, M. L., Holck, J. & Meyer, A. S., 2019, In : ACS Sustainable Chemistry and Engineering. 7, 12, p. 10425-10434 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

45 Downloads (Pure)

Large-scale fabrication of microfluidic chips with three-dimensional microstructures for point of care application

Nguyen, T., Aaydha Chidambara, V., Bang, D. D. & Wolff, A., 2019, Proceedings of the 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences. p. 1658-1659 2 p. M237.h

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Open Access
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62 Downloads (Pure)

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

Vasudevan, S., Kajtez, J., Bunea, AI., Gonzalez‐Ramos, A., Ramos‐Moreno, T., Heiskanen, A., Kokaia, M., Larsen, N. B., Martínez‐Serrano, A., Keller, S. S. & Emnéus, J., 2019, In : Advanced Science. 9 p., 1902011.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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144 Downloads (Pure)

Levels of Systemic Low-grade Inflammation in Pregnant Mothers and Their Offspring are Correlated

Fink, N. R., Chawes, B., Bønnelykke, K., Thorsen, J., Stokholm, J., Rasmussen, M. A., Brix, S. & Bisgaard, H., 2019, In : Scientific Reports. 9, 1, 9 p., 3043.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Lipid Dynamics and Phase Transition within α-Synuclein Amyloid Fibrils

Galvagnion, C., Topgaard, D., Makasewicz, K., Buell, A. K., Linse, S., Sparr, E. & Dobson, C. M., 2019, In : Journal of Physical Chemistry Letters. 10, p. 7872-7877 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

35 Downloads (Pure)

Localized Laser Pyrolysis of SU-8 by Addition of Absorber

Ludvigsen, E., Pedersen, N. R., Zhu, X., Marie, R., Mackenzie, D., Petersen, D. H., Kristensen, A., Emnéus, J. & Keller, S. S., 2019.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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6 Downloads (Pure)

Long-Term Exposure to Inflammation Induces Differential Cytokine Patterns and Apoptosis in Dendritic Cells

Carstensen, L. S., Lie-Andersen, O., Obers, A., Crowther, M. D., Svane, I. M. & Hansen, M., 2019, In : Frontiers in Immunology. 10, 11 p., 2702.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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57 Downloads (Pure)

Low concentration of serum immunoglobulin G is associated with pre-weaning diarrhea in young mink kits (Neovison vison)

Mathiesen, R., Chriél, M., Struve, T. & Heegaard, P. M. H., 2019, In : Acta Veterinaria Scandinavica. 61, 1, 8 p., 26.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Mapping the N-Terminome in Tissue Biopsies by PCT-TAILS

Bundgaard, L., Savickas, S. & auf dem Keller, U., 2019, ADAMTS Proteases. Vol. 2043. p. 285-296 12 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

61 Downloads (Pure)

Marine chitinolytic pseudoalteromonas represents an untapped reservoir of bioactive potential

Paulsen, S. S., Strube, M. L., Bech, P. K., Gram, L. & Sonnenschein, E. C., 2019, In : mSystems. 4, 4, 12 p., e00060-19.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Markers of collagen formation and degradation reflect renal function and predict adverse outcomes in patients with type 1 diabetes

Pilemann-Lyberg, S., Rasmussen, D. G. K., Hansen, T. W., Tofte, N., Winther, S. A., Nielsen, S. H., Theilade, S., Karsdal, M. A., Genovese, F. & Rossing, P., 2019, In : Diabetes Care. 42, 9, p. 1760-1768 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

23 Downloads (Pure)
Open Access
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66 Downloads (Pure)

Mesenchymal stromal cell activation by breast cancer secretomes in bioengineered 3D microenvironments

Blache, U., Horton, E. R., Xia, T., Schoof, E. M., Blicher, L. H., Schönenberger, A., Snedeker, J. G., Martin, I., Erler, J. T. & Ehrbar, M., 2019, In : Life Science Alliance. 2, 3, 15 p., e201900304.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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