Department of Biotechnology and Biomedicine

  • Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output 2011 2020

2011

Ecological and Clinical Consequences of Antibiotic Subsistence by Environmental Microbes

Dantas, G. & Sommer, M. O. A., 2011, Antimicrobial Resistance in the Environment. Wiley, p. 29-41

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

2014
3 Downloads (Pure)
Open Access
File

Novel DNA barcodes for detection, idenfication and tracking of stachybotrys and chaetomium species

Lewinska, A. M., Hoof, J. B., Peuhkuri, R. H., Rode, C. & Andersen, B., 2014, Proceedings of Indoor Air 2014. International Society of Indoor Air Quality and Climate, p. 281-288 8 p.

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

2016
66 Downloads (Pure)

An Integrated Genomics Framework for System-Level Cell Factory Design

Cardinale, S., Ye, L. & Sommer, M. O. A., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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Anti-Inflammatory Inhibitors Targeting Jak and Ikk Have An Anabolic Effect on Type II Collagen Turnover ex Vivo

Kjelgaard-Petersen, C. F., Bay-Jensen, A-C., Karsdal, M. A., Hagglund, P. & Thudium, C. S., 2016, In : Annals of the Rheumatic Diseases. 75, Suppl. 2, p. 185-186 THU0024.

Research output: Contribution to journalJournal articleResearchpeer-review

75 Downloads (Pure)

A snapshot into ATP-binding cassette transporter mediated glycan uptake in probiotic bifidobacteria

Hansen, M. E., Theilmann, M. C., Saburi, W., Fredslund, F., Svensson, B., Lo Leggio, L., Licht, T. R., Slotboom, D. J. & Abou Hachem, M., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
300 Downloads (Pure)

Aspergillus is monophyletic: Evidence from multiple gene phylogenies and extrolites profiles

Kocsubé, S., Perrone, G., Magistà, D., Houbraken, J., Varga, J., Szigeti, G., Hubka, V., Hong, S-B., Frisvad, J. C. & Samson, R. A., 2016, In : Studies in Mycology. 85, p. 199-213 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
371 Downloads (Pure)

Biotechnological Trends in Spider and Scorpion Antivenom Development

Laustsen, A. H., Solà, M., Jappe, E. C., Oscoz Cob, S., Lauridsen, L. P. & Engmark, M., 2016, In : Toxins. 8, 8, 33 p., 226.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Chemotaxonomy of the genus Stemphylium

Olsen, K. J. K. & Andersen, B., 2016, In : Planta Medica. 81, S 01, 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Chondrocyte pro-proliferative compounds may utilize extracellular matrix remodeling processes to regenerate cartilage

Reker, D., Kjelgaard-Petersen, C. F., Gigout, A., Ladel, C., Siebuhr, A., Michealis, M., Karsdal, M. A. & Bay-Jensen, A., 2016, In : Osteoarthritis and Cartilage. 24, Suppl. 1, p. S157 1 p., 261.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

63 Downloads (Pure)

CHO On A Detox: Removing By-Product Formation Through Cell Engineering

Pereira, S., Kildegaard, H. F. & Andersen, M. R., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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Curbing the development and spread of 'high risk' bacterial pathogens

Jelsbak, L., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
319 Downloads (Pure)

Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper

Meyer, V., Andersen, M. R., Brakhage, A. A., Braus, G. H., Caddick, M. X., Cairns, T. C., de Vries, R. P., Haarmann, T., Hansen, K., Hertz-Fowler, C., Krappmann, S., Mortensen, U. H., Peñalva, M. A., Ram, A. F. J. & Head, R. M., 2016, In : Fungal Biology and Biotechnology. 3, 1, 17 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Defining carbohydrate binding of glucan phosphatases via Affinity gel electrophoresis

Auger, K., Raththagala, M., Wilkens, C., Svensson, B. & Gentry, M., 2016, In : FASEB Journal. 30, Suppl. 1, 1113.2.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Detection of fungal growth and its influence on gypsum wallboard – in the process of creating sustainable building materials

Lewinska, A. M., Lilje, O., Foley, M., Trimby, P., Bjerring, M., Vosegaard, T., Peuhkuri, R. H., Rode, C., Grumsen, F. B., Hoof, J. B. & Andersen, B., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
163 Downloads (Pure)

Diversity and taxonomy of Chaetomium and chaetomium-like fungi from indoor environments

Wang, X. W., Houbraken, J., Groenewald, J. Z., Meijer, M., Andersen, B., Nielsen, K. F., Crous, P. W. & Samson, R. A., 2016, In : Studies in Mycology. 84, p. 145-224 80 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Effects of musculoskeletal related growth factors on cartilage extracellular matrix formation

Kjelgaard-Petersen, C. F., Reker, D., Gudmann, N. S., Gigout, A., Siebuhr, A., Karsdal, M. A., Michealis, M., Ladel, C. & Bay-Jensen, A., 2016, In : Osteoarthritis and Cartilage. 24, Suppl. 1, p. S155 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

42 Downloads (Pure)

Glycosyltransferase glycosylating flavokermesic acid and/or kermesic acid

Kannangara, R. M., Bennedsen, M., Madsen, B., Binderup, K., Thrane, U., Frandsen, R. J. N., Mortensen, U. H., Møller, B. L. & Okkels, F. T., 26 Oct 2016, IPC No. C12P 7/ 66 A I, Patent No. EP3083950, 29 Nov 2017, Priority date 18 Dec 2014, Priority No. WO2014EP78540

Research output: Patent

Open Access
File
189 Downloads (Pure)

Improving heterologous production of phenylpropanoids in Saccharomyces cerevisiae by tackling an unwanted side reaction of Tsc13, an endogenous double-bond reductase

Lehka, B. J., Eichenberger, M., Bjorn-Yoshimoto, W. E., Garcia Vanegas, K., Buijs, N. A., Jensen, N. B., Dyekaejr, J. D., Jenssen, H., Simon, E. & Naesby, M., 2016, In : FEMS Yeast Research. 17, 1, 12 p., fox004.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Increasing Oil Bodies in Physcomitrella patens by Overexpressing Oil Body- Associated Proteins

Bae, H., Peramuna, A. V. & Simonsen, H. T., 2016.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access

Influence of the medium and preferred cereal substrate on secondary metabolite production by species from Penicillium series Viridicata

Hallas-Møller, M., Nielsen, K. F. & Frisvad, J. C., 2016, In : Planta Medica. 81, S 01, 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Magnetosome production and functionalization

Anyaogu, D. C., Zhuang, S., Mortensen, U. H. & Hobley, T. J., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
154 Downloads (Pure)

Multi-omic profiling of EPO producing Chinese hamster ovary cell panel reveals metabolic adaptation to heterologous protein production

Ley, D., Kazemi Seresht, A., Engmark, M., Magdenoska, O., Nielsen, K. F., Kildegaard, H. F. & Andersen, M. R., 2016. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
170 Downloads (Pure)

Plasma amino acid levels are elevated in young, healthy low birth weight men exposed to short-term high-fat overfeeding

Ribel-Madsen, A., Hellgren, L., Brøns, C., Ribel-Madsen, R., B. Newgard, C. & A. Vaag, A., 2016, In : Physiological Reports. 4, 23, 13 p., e13044.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
154 Downloads (Pure)

Polyphasic taxonomy of Aspergillus section Cervini

Chen, A. J., Varga, J., Frisvad, J. C., Jiang, X. Z. & Samson, R. A., 2016, In : Studies in Mycology. 85, p. 65–89

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Prediction of secondary metabolite encoding genes based on chemical structure analysis

Petersen, T. I., Nielsen, M. L., Hoeck, C., Gezgin, Y., Frandsen, R. J. N., Nielsen, K. F. & Larsen, T. O., 2016, In : Planta Medica. 81, S 01, 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

210 Downloads (Pure)
Open Access
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Recycled organic building materials are prone to fungal growth

Andersen, B., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access

Regulation of host metabolism and immunity by the gut microbiome

Laursen, J. M., 2016, Technical University of Denmark. 128 p.

Research output: Book/ReportPh.D. thesisResearch

129 Downloads (Pure)

Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study

Bager, C. L., Willumsen, N., Kehlet, S. N., Hansen, H. B., Bay-Jensen, A-C., Leeming, D. J., Møller, K. D., Neergaard, J., Christiansen, C., Høgdall, E. & Karsdal, M. A., 2016, In : Cancer Epidemiology, Biomarkers & Prevention. 25, 9, p. 1348-1355

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Seamless gene editing in Aspergillus species, using CRISPR-Cas9

Nødvig, C. S., Hoof, J. B. & Mortensen, U. H., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access

Serological biomarkers reflecting collagen remodeling of the tumor microenvironment are elevated in metastatic colorectal cancer

Kehlet, S. N., Sanz-Pamplona, R., Leeming, D. J., Karsdal, M. A. & Moreno, V., 2016. 2 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

125 Downloads (Pure)

Targeting the DCIR Receptor with a TLR7 Agonist Specifically Activates Monocytes and DCs

Klauber, T. C. B., Laursen, J. M., Maj, R., Pedersen, S. B., Jensen, S. S. & Andresen, T. L., 2016.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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Transglycosylation reaction of bacterial N-acetyl hexosaminidases towards human milk oligosaccharide core structures

Visnapuu, T., Katayama, T., Pedersen, L. H., Lie, A., Stougaard, P. & Svensson, B., 2016.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

134 Downloads (Pure)

Use of heterologous expressed polyketide synthase and small molecule foldases to make aromatic and cyclic compounds

Frandsen, R. J. N., Mortensen, U. H., Coumou, H., Kannangara, R., Madsen, L., Nafisi, M., Ranberg, J. A., Kongstad, K. T., T. Okkels, F., Khorsand-Jamal, P. & Stærk, D., 15 Dec 2016, IPC No. C12P 19/ 60 A I, Patent No. WO2016198623, 15 Dec 2016, Priority date 10 Jun 2015, Priority No. EP20150171430

Research output: Patent

Open Access
File
110 Downloads (Pure)

Use of octaketide synthases to produce kermesic acid and flavokermesic acid

Møller, B. L., Madsen, B., Stærk, D., Okkels, F. T., Andersen-Ranberg, J., Kongstad, K. T., Binderup, K., Bennedsen, M., Nafisi, M., Khorsand-Jamal, P., Kannangara, R. M., Mortensen, U. H., Thrane, U. & Frandsen, R. J. N., 15 Dec 2016, IPC No. C12P 17/ 06 A I, Patent No. WO2016198564, 15 Dec 2016, Priority date 10 Jun 2015, Priority No. EP20150171375

Research output: Patent

Open Access
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2017

3D protein-structure-oriented discovery of clinical relation across chronic lymphocytic leukemia patients

Mochament, K., Agathangelidis, A., Polychronidou, E., Palaskas, C., Kalamaras, E., Moschonas, P., Stamatopoulos, K., Chailyan, A., Overby, N., Marcatili, P., Hadzidimitriou, A. & Tzovaras, D., 2017, In : Lecture Notes in Computer Science. 10209, p. 139-150

Research output: Contribution to journalConference articleResearchpeer-review

258 Downloads (Pure)

A CRISPR/Cas9 based toolbox for efficient genome editing of filamentous fungi

Mortensen, U. H., Nødvig, C. S., Jarczynska, Z. D., Nielsen, M. L., Kirchner, F. H. & Hoof, J. B., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
47 Downloads (Pure)

Activation of Toll-like Receptor 2 in Human Synovium Explants Increase Tissue Turnover and Secretion of Interleukin-6

Sharma, N., Kayed, A., Kjelgaard-Petersen, C. F., Christiansen, T. G., Karsdal, M., Thudium, C. S. & Bay-Jensen, A-C., 2017, In : Arthritis and Rheumatology. 69, 4 p., 1063.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
File
260 Downloads (Pure)

A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria

Kildgaard, S., Subko, K., Phillips, E., Goidts, V., de la Cruz, M., Díaz, C., Gotfredsen, C. H., Andersen, B., Frisvad, J. C., Nielsen, K. F. & Larsen, T. O., 2017, In : Marine Drugs. 15, 8, 253.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Advanced fabrication of porous ceramic multilayers for membrane applications

Kaiser, A., Della Negra, M., Pinelo, M., Zhang, W. A. & Bjørnetun Haugen, A., 2017, Proceedings of ICM 2017. 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

60 Downloads (Pure)

A family of microbial lysine transporter polypeptides

Malla, S., Sommer, M. O. A., van der Helm, E., Wieschalka, S. & Förster, J., 26 May 2017, IPC No. C12P 13/ 08 A I, Patent No. WO2017085241, 26 May 2017, Priority date 19 Nov 2015, Priority No. EP20150195401

Research output: Patent

Open Access
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Affinity Electrophoresis for Analysis of Catalytic Module-Carbohydrate Interactions

Cockburn, D., Wilkens, C. & Svensson, B., 2017, Protein-Carbohydrate Interactions: Methods and Protocols. Abbott, D. W. & van Bueren, A. L. (eds.). Springer, Vol. 1588. p. 119-127 (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

118 Downloads (Pure)

A highly active endo-levanase BT1760 of a dominant mammalian gut commensal Bacteroides thetaiotaomicron cleaves not only various bacterial levans, but also levan of timothy grass

Mardo, K., Visnapuu, T., Vija, H., Aasamets, A., Viigand, K. & Alamäe, T., 2017, In : PLOS ONE. 12, 1, 25 p., e0169989.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
171 Downloads (Pure)

Allergic Sensitization at School Age is a Systemic Low-grade Inflammatory Disorder

Chawes, B. L., Stokholm, J., Schoos, A-M. M., Fink, N. R., Pedersen, S. B. & Bisgaard, H., 2017, In : Allergy. 72, 7, p. 1073-1080

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
169 Downloads (Pure)

A meta-proteomics approach to study the interspecies interactions affecting microbial biofilm development in a model community

Herschend, J., Damholt, Z. B. V., Marquard, A. M., Svensson, B., Sørensen, S. J., Hägglund, P. & Burmølle, M., 2017, In : Scientific Reports. 7, 1, 13 p., 16483.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
184 Downloads (Pure)

A modular metabolic engineering approach for the production of 1,2-propanediol from glycerol by Saccharomyces cerevisiae

Islam, Z-U., Klein, M., Aßkamp, M. R., Ødum, A. S. R. & Nevoigt, E., 2017, In : Metabolic Engineering. 44, p. 223-235

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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An experimental approach to studying the role of Horizontal Gene Transfer in shaping fungal secondary metabolism

de Reus, P. E., Nielsen, K. F. N. & Frandsen, R. J. N., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

314 Downloads (Pure)

An extracellular cell-attached pullulanase confers branched α-glucan utilization in human gut Lactobacillus acidophilus

Møller, M. S., Goh, Y. J., Rasmussen, K. B., Cypryk, W., Celebioglu, H. U., Klaenhammer, T. R., Svensson, B. & Abou Hachem, M., 2017, In : Applied and Environmental Microbiology. 83, 10, 35 p., AEM.00402-17.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
186 Downloads (Pure)

A novel biomarker of laminin turnover is associated with mortality and disease progression in chronic kidney disease

Nielsen, S. H., Guldager Kring Rasmussen, D., Fenton, A., Jesky, M., Ferro, C., Karsdal, M., Genovese, F. & Cockwell, P., 2017, In : Nephrology, Dialysis, Transplantation. 32, Suppl. 3, 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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