Department of Biotechnology and Biomedicine

  • Søltofts Plads, Bygning 221

    DK-2800 Kgs. Lyngby

    Denmark

Research Output 2011 2020

2020

Chemical Diversity of Locked Nucleic Acid-Modified Antisense Oligonucleotides Allows Optimization of Pharmaceutical Properties

Papargyri, N., Pontoppidan, M., Andersen, M. R., Koch, T. & Hagedorn, P. H., 6 Mar 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 706-717

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
1 Downloads (Pure)

Complete Genome Sequences of 13 Bacillus subtilis Soil Isolates for Studying Secondary Metabolite Diversity

Kiesewalter, H. T., Lozano-Andrade, C. N., Maróti, G., Snyder, D., Snyder, D., Jørgensen, T. S., Weber, T. & Kovács, Á. T., 2020, In : Microbiology Resource Announcements. 9, 2, 3 p., e01406-19.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Development of a high-throughput real-time PCR system for detection of enzootic pathogens in pigs

Goecke, N. B., Hjulsager, C. K., Krog, J. S., Skovgaard, K. & Larsen, L. E., 2020, (Accepted/In press) In : Journal of Veterinary Diagnostic Investigation.

Research output: Contribution to journalJournal articleResearchpeer-review

Direct separation of acetate and furfural from xylose by nanofiltration of birch pretreated liquor: Effect of process conditions and separation mechanism

Zdarta, J., Thygesen, A., Holm, M. S., Meyer, A. S. & Pinelo, M., 2020, In : Separation and Purification Technology. 239, 11 p., 116546.

Research output: Contribution to journalJournal articleResearchpeer-review

Fungal communities in rice cultivated in different Brazilian agroclimatic zones: From field to market

Katsurayama, A. M., Martins, L. M., Iamanaka, B. T., Fungaro, M. H. P., Silva, J. J., Pitt, J. I., Frisvad, J. C. & Taniwaki, M. H., 2020, In : Food Microbiology. 87, 8 p., 103378.

Research output: Contribution to journalJournal articleResearchpeer-review

2 Downloads (Pure)

Identification and Characterization of a β-N-Acetylhexosaminidase with a Biosynthetic Activity from the Marine Bacterium Paraglaciecola hydrolytica S66T

Visnapuu, T., Teze, D., Kjeldsen, C., Lie, A., Duus, J. Ø., André-Miral, C., Pedersen, L. H., Stougaard, P. & Svensson, B., 2020, In : International Journal of Molecular Sciences . 21, 2, 22 p., 417.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
10 Downloads (Pure)

Metal ions weaken the hydrophobicity and antibiotic resistance of Bacillus subtilis NCIB 3610 biofilms

Falcón García, C., Kretschmer, M., Lozano-Andrade, C. N., Schönleitner, M., Dragoŝ, A., Kovács, Á. T. & Lieleg, O., 2020, In : NPJ biofilms and microbiomes. 6, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Qualitative proteomic comparison of metabolic and CM-like protein fractions in old and modern wheat Italian genotypes by a shotgun approach

Di Francesco, A., Saletti, R., Cunsolo, V., Svensson, B., Muccilli, V., Vita, P. D. & Foti, S., 2020, In : Journal of Proteomics. 211, 14 p., 103530.

Research output: Contribution to journalJournal articleResearchpeer-review

5 Downloads (Pure)

Roles of the N-terminal domain and remote substrate binding subsites in activity of the debranching barley limit dextrinase

Andersen, S., Svensson, B. & Møller, M. S., 2020, In : B B A - Proteins and Proteomics. 1868, 1, 24 p., 140294.

Research output: Contribution to journalJournal articleResearchpeer-review

Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture

Karimi Alavijeh, M., Meyer, A. S., Gras, S. L. & Kentish, S. E., 2020, In : Biochemical Engineering Journal. 154, 10 p., 107459.

Research output: Contribution to journalJournal articleResearchpeer-review

22 Downloads (Pure)

Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent

Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawia, M. S., Møller, B. L. & Laursen, T., 2020, In : Phytochemistry. 170, 9 p., 112214.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Synergetic design of enlarged surface area and pseudo-capacitance for fiber-shaped supercapacitor yarn

Le, T. S., Truong, T. K., Huynh, V. N., Bae, J. & Suh, D., 2020, In : Nano Energy. 67, 8 p., 104198.

Research output: Contribution to journalJournal articleResearchpeer-review

2019

#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide

López-Goñi, I., Giner-Lamia, J., Álvarez-Ordoñez, A., Benitez-Páez, A., Claessen, D., Cortesao, M., de Toro, M., García-Ruano, D., Granato, E. T., Kovács, ÁT., Romalde, J. L., Sana, T. G., Sánchez-Angulo, M., Sangari, F. J., Smits, W. K., Sturm, T., Thomassin, J. L., Valdehuesa, K. N. G. & Zapotoczna, M., 2019, In : FEMS Microbiology Letters. 366, 11, 4 p., fnz141.

Research output: Contribution to journalJournal articleResearchpeer-review

1H, 13C and 15N backbone and side-chain assignment of a carbohydrate binding module from a xylanase from Roseburia intestinalis

Madland, E., Kitaoku, Y., Sætrom, G. I., Leth, M. L., Ejby, M., Abou Hachem, M. & Aachmann, F. L., 2019, In : Biomolecular N M R Assignments. 13, 1, p. 55-58 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

3.53 Synthetic Biology: An Overview

de Carvalho, Â., Garcia Vanegas, K., Pereira, F., Theobald, S. & Takos, A., 2019, Comprehensive Biotechnology 3rd Edition. Moo-Young, M. (ed.). 3 ed. Pergamon Press, p. 659-670 12 p.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

232 Downloads (Pure)

A-, B- and C-type prymnesins are clade specific compounds and chemotaxonomic markers in Prymnesium parvum

Binzer, S. B., Svenssen, D. K., Daugbjerg, N., Alves-de-Souza, C., Pinto, E., Hansen, P. J., Larsen, T. O. & Varga, E., 2019, In : Harmful Algae. 81, p. 10-17

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

A biochemical comparison of fungal GH6 cellobiohydrolases

Christensen, S. J., Krogh, K. B. R. M., Spodsberg, N., Borch, K. & Westh, P., 2019, In : Biochemical Journal. 476, 15, p. 2157-2172 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

A biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis

Nielsen, S. H., Tengryd, C., Edsfeldt, A., Brix, S., Genovese, F., Bengtsson, E., Karsdal, M., Leeming, D. J., Nilsson, J. & Goncalves, I., 2019, In : Journal of Internal Medicine. 285, 1, p. 118-123 6 p.

Research output: Contribution to journalJournal articleCommunication

A biorefinery approach to bioethanol and bioelectricity co-production from tropical seaweeds

Offei, F., Mensah, M., Kemausuor, F. & Thygesen, A., 2019, In : Journal of Applied Phycology. 31, 6, p. 3899-3913 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

94 Downloads (Pure)

A carbohydrate-binding family 48 module enables feruloyl esterase action on polymeric arabinoxylan

Holck, J., Fredslund, F., Møller, M. S., Brask, J., Krogh, K. B. R. M., Lange, L., Welner, D. H., Svensson, B., Meyer, A. S. & Wilkens, C., 2019, In : Journal of Biological Chemistry. 294, 46, p. 17339-17353 16 p., jbc.RA119.009523.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

A chemo-enzymatic approach for the synthesis of human milk oligosaccharide backbone structures

Muschiol, J. & Meyer, A. S., 2019, In : Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences. 74, 3-4, p. 85-89 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

66 Downloads (Pure)
Open Access
File

A human touch to snakebite antivenoms

Laustsen, A. H., 2019, In : Toxicon. 158, Suppl. 1, p. S16-S16 1 p., 52.

Research output: Contribution to journalJournal articleResearchpeer-review

149 Downloads (Pure)

Alginate Trisaccharide Binding Sites on the Surfaceof β-Lactoglobulin Identified by NMR Spectroscopy: Implications for Molecular Network Formation

Stender, E. G. P., Birch, J., Kjeldsen, C., Nielsen, L. D., Duus, J. Ø., Kragelund, B. B. & Svensson, B., 2019, In : ACS Omega. 4, 4, p. 6165-6174 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
66 Downloads (Pure)

Analysis of Pseudomonas putida growth on non-trivial carbon sources using transcriptomics and genome-scale modeling

D'Arrigo, I., Cardoso, J. G. R., Rennig, M., Sonnenschein, N., Herrgård, M. J. & Long, K. S., 2019, In : Environmental Microbiology Reports. 11, 2, p. 87-97 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Ancestral Sequence Reconstruction – eine neue Methode für die Erzeugung thermostabiler Enzyme?

Muschiol, J., 2019, In : BioSpektrum. 25, 1, p. 52-52 1 p.

Research output: Contribution to journalComment/debateResearchpeer-review

53 Downloads (Pure)

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

Agerschou, E. D., Flagmeier, P., Saridaki, T., Galvagnion, C., Komnig, D., Heid, L., Prasad, V., Shaykhalishahi, H., Willbold, D., Dobson, C. M., Voigt, A., Falkenburger, B., Hoyer, W. & Buell, A. K., 2019, In : eLife. 8, 31 p., e46112.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

An integrated strategy for the effective production of bristle protein hydrolysate by the keratinolytic filamentous bacterium Amycolatopsis keratiniphila D2

Falco, F. C., Espersen, R., Svensson, B., Gernaey, K. V. & Eliasson Lantz, A., 2019, In : Waste Management. 89, p. 94-102

Research output: Contribution to journalJournal articleResearchpeer-review

A novel scale-down mimic of perfusion cell culture using sedimentation in an automated microbioreactor (SAM)

Kreye, S., Stahn, R., Nawrath, K., Goralczyk, V., Zoro, B. & Goletz, S., 2019, In : Biotechnology Progress. 35, 5, 11 p., e2832.

Research output: Contribution to journalJournal articleResearchpeer-review

82 Downloads (Pure)

A novel starch-binding laccase from the wheat pathogen Zymoseptoria tritici highlights the functional diversity of ascomycete laccases

Haddad Momeni, M., Bollella, P., Ortiz, R., Thormann, E., Gorton, L. & Abou Hachem, M., 2019, In : B M C Biotechnology. 19, 12 p., 61.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
4 Downloads (Pure)

Anti-protozoal activity of extracts from chicory (Cichorium intybus) against Cryptosporidium parvum in cell culture

Woolsey, I. D., Valente, A. H., Williams, A. R., Thamsborg, S. M., Simonsen, H. T. & Enemark, H. L., 2019, In : Scientific Reports. 9, 1, 9 p., 20414.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Application of a genome-scale model in tandem with enzyme assays for identification of metabolic signatures of high and low CHO cell producers

Calmels, C., Arnoult, S., Ben Yahia, B., Malphettes, L. & Andersen, M. R., 2019, In : Metabolic Engineering Communications. 9, 11 p., e00097.

Research output: Contribution to journalJournal articleResearchpeer-review

Application of chemometric tools for the comparison of volatile profile from raw and roasted regional and foreign almond cultivars (Prunus dulcis)

Oliveira, I., Malheiro, R., Meyer, A. S., Pereira, J. A. & Gonçalves, B., 2019, In : Journal of Food Science and Technology. 56, 8, p. 3764-3776 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

A practical approach to steady-state kinetic analysis of cellulases acting on their natural insoluble substrate

Kari, J., Christensen, S. J., Andersen, M., Baiget, S. S., Borch, K. & Westh, P., 2019, In : Analytical Biochemistry. 586, 7 p., 113411.

Research output: Contribution to journalJournal articleResearchpeer-review

8 Downloads (Pure)

A rare thioquinolobactin siderophore present in a bioactive Pseudomonas sp. DTU12.1

Sazinas, P., Hansen, M. L., Aune, M. I., Fischer, M. H. & Jelsbak, L., 2019, (Accepted/In press) In : Genome Biology and Evolution. 14 p., evz267.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
95 Downloads (Pure)

Are There Circadian Clocks in Non-Photosynthetic Bacteria?

Sartor, F., Eelderink-Chen, Z., Aronson, B., Bosman, J., Hibbert, L. E., Dodd, A. N., Kovács, Á. T. & Merrow, M., 2019, In : Biology. 8, 2, 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
29 Downloads (Pure)

A sensitive, specific and simple loop mediated isothermal amplification method for rapid detection of campylobacter spp. In broiler production

Than Linh, Q., Nordentoft, S., Aaydha Chidambara, V., Anh, T. N., Engelsmann, P., Sun, Y., Madsen, M., Bang, D. D. & Wolff, A., 2019, In : Frontiers in Microbiology. 10, 10 p., 2443.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
42 Downloads (Pure)

Asp271 is critical for substrate interaction with the surface binding site in β-agarase A from Zobellia galactanivorans

Wilkens, C., Tiwari, M. K., Webb, H., Jam, M., Czjzek, M. & Svensson, B., 2019, In : Proteins: Structure, Function, and Bioinformatics. 87, 1, p. 34-40

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Aspergillus section Flavi diversity and the role of A. novoparasiticus in aflatoxin contamination in the sugarcane production chain

Iamanaka, B. T., de Souza Lopes, A., Martins, L. M., Frisvad, J. C., Medina, A., Magan, N., Sartori, D., Massi, F. P., Fungaro, M. H. P. & Taniwaki, M. H., 2019, In : International Journal of Food Microbiology. 293, p. 17-23

Research output: Contribution to journalJournal articleResearchpeer-review

43 Downloads (Pure)

Assessing specialized metabolite diversity in the cosmopolitan plant genus Euphorbia l.

Ernst, M., Nothias, L. F., van der Hooft, J. J. J., Silva, R. R., Saslis-Lagoudakis, C. H., Grace, O. M., Martinez-Swatson, K., Hassemer, G., Funez, L. A., Simonsen, H. T., Medema, M. H., Staerk, D., Nilsson, N., Lovato, P., Dorrestein, P. C. & Rønsted, N., 2019, In : Frontiers in Plant Science. 10, 15 p., 846.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
12 Downloads (Pure)

Assessing the potential of micro-fermentations through screening and media optimisation of recombinant β-carotene production by the yeast Yarrowia lipolytica.

Jacobsen, I. H., Ledesma-Amaro, R. & Martinez Ruiz, J. L., 2019. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
56 Downloads (Pure)

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

Röder, C., Vettore, N., Mangels, L. N., Gremer, L., Ravelli, R. B. G., Willbold, D., Hoyer, W., Buell, A. K. & Schröder, G. F., 2019, In : Nature Communications. 10, 1, 9 p., 3754.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Atrorosins: a new subgroup of Monascus pigments from Talaromyces atroroseus

Isbrandt, T., Tolborg, G., Ødum, A. S. R., Workman, M. & Larsen, T. O., 2019, In : Applied Microbiology and Biotechnology. p. 1-8 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

AU Content in the MicroRNA Sequence Influences its Stability After Heat Treatment

López, A. G., Brogaard, L., Heegaard, P. M. H., Cirera, S. & Skovgaard, K., 2019, In : MicroRNA. 8, 3, p. 216-222 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Bacillus subtilis

Kovács, Á. T., 2019, In : Trends in Microbiology. 27, 8, p. 724-725 2 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Bacterial Candidates for Colonization and Degradation of Marine Plastic Debris

Roager, L. & Sonnenschein, E. C., 2019, In : Environmental Science and Technology. 53, 20, p. 11636-11643 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

BCAT1 and BCAT2 disruption in CHO cells has cell line-dependent effects

Pereira, S., Ley, D., Schubert, M., Grav, L. M., Kildegaard, H. F. & Andersen, M. R., 2019, In : Journal of Biotechnology. 306, p. 24-31 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

101 Downloads (Pure)

Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy

Pucca, M. B., Cerni, F. A., Oliveira, I. S., Jenkins, T. P., Argemí, L., Sørensen, C. V., Ahmadi, S., Barbosa, J. E. & Laustsen, A. H., 2019, In : Frontiers in Immunology. 10, 15 p., 2090.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
19 Downloads (Pure)
Open Access
File

Bioconversion of xylose to xylonic acid via co-immobilized dehydrogenases for conjunct cofactor regeneration

Bachosz, K., Synoradzki, K., Staszak, M., Pinelo, M., Meyer, A. S., Zdarta, J. & Jesionowski, T., 2019, In : Bioorganic Chemistry. 93, 10 p., 102747.

Research output: Contribution to journalJournal articleResearchpeer-review