Center for Nanomedicine and Theranostics

2024

Chemical synthesis of natural and azido-modified UDP-rhamnose and -arabinofuranose for glycan array-based characterization of plant glycosyltransferases

Pasini, I., Ruprecht, C., Osswald, U., Bittmann, A., Maltrovsky, L., Romanò, C., Clausen, M. H. & Pfrengle, F., 2024, In: Chemical Communications. 60, 70, p. 9368-9371

Research output: Contribution to journal › Journal article › Research › peer-review

Comparative Evaluation of UV-Vis Spectroscopy-Based Approaches for Hemoglobin Quantification: Method Selection and Practical Insights

Coll-Satue, C., Jansman, M. M. T. & Hosta-Rigau, L., 2024, In: Biomolecules. 14, 9, 17 p., 1046.

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2022

Accelerated blood clearance and hypersensitivity by PEGylated liposomes containing TLR agonists

Stavnsbjerg, C., Christensen, E., Münter, R., Henriksen, J. R., Fach, M., Parhamifar, L., Christensen, C., Kjaer, A., Hansen, A. E. & Andresen, T. L., 2022, In: Journal of controlled release. 342, p. 337-344

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Synthesis and evaluation of hydrogen peroxide sensitive tofacitinib prodrugs

Previtali, V., Keiding, U. B., Olsen, A. H., Peiró Cadahía, J., Clausen, A. S., Kjaer, A., Andresen, T. L., Hansen, A. E. & Clausen, M. H., 2022, In: European Journal of Medicinal Chemistry Reports. 4, 8 p., 100019.

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2021

Carbohydrate based biomarkers enable hybrid near infrared fluorescence and⁶⁴cu based radio-guidance for improved surgical precision

Wang, W., Hansen, A. E., Sun, H., Fliedner, F. P., Kjaer, A., Jensen, A. I., Andresen, T. L. & Henriksen, J. R., 2021, In: Nanotheranostics. 5, 4, p. 448-460

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2020

Induced cell migration based on a bioactive hydrogel sheet combined with a perfused microfluidic system

Jafarkhani, M., Salehi, Z., Mashayekhan, S., Kowsari-Esfahan, R., Orive, G., Dolatshahi-Pirouz, A., Bonakdar, S. & Shokrgozar, M. A., 2020, In: Biomedical Materials (Bristol). 15, 4, 15 p., 045010.

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2019

Acylated Flavonoid Glycosides are the Main Pigments that Determine the Flower Colour of the Brazilian Native Tree Tibouchina pulchra (Cham.) Cogn.

Rezende, F. M., Ferreira, M. J. P., Clausen, M. H., Rossi, M. & Furlan, C. M., 2019, In: Molecules. 24, 4, 16 p., 718.

Research output: Contribution to journal › Journal article › Research › peer-review

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Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 2019, In: Journal of Controlled Release. 295, p. 237-249 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2017

Applying fluorescence correlation spectroscopy to investigate peptide-induced membrane disruption

Kristensen, K., Henriksen, J. R. & Andresen, T. L., 2017, Antimicrobial Peptides: Methods and Protocols. Hansen, P. R. (ed.). Springer, p. 159-180 22 p. (Methods in Molecular Biology, Vol. 1548).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

Wewer Albrechtsen, N. J., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jørgensen, N. B., Gabe, M. N., Balk-Møller, E., Albrechtsen, R., Winther-Sørensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsbøll, T., Eliasen, R. & Bojsen-Møller, K. N. & 9 others, Idorn, T., Deacon, C. F., Knop, F. K., Rosenkilde, M. M., Hartmann, B., Feldt-Rasmussen, B., Mann, M., Madsbad, S. & Holst, J. J., 2017, In: Cell Reports. 21, 6, p. 1452-1460

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Convenient one-step synthesis of 5-carboxy-seminaphthofluoresceins

Hammershøj, P., Thyhaug, E., Harris, P., Ek, P. K., Andresen, T. L. & Clausen, M. H., 2017, In: Tetrahedron Letters. 58, 16, p. 1611-1615

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Convergent strategy for the synthesis of S-linked oligoxylans

Bonora, B., Boos, I. & Clausen, M. H., 2017, In: Carbohydrate Research. p. 53-57

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Enhanced efficacy of sublingual immunotherapy by liposome-mediated delivery of allergen

Aliu, H., Rask, C., Brimnes, J. & Andresen, T. L., 2017, In: International Journal of Nanomedicine. 12, p. 8377-8388

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2016

⁶⁴Cu-ATSM Reflects pO₂ Levels in Human Head and Neck Cancer Xenografts but Not in Colorectal Cancer Xenografts: Comparison with ⁶⁴CuCl₂

Li, F., Jørgensen, J. T., Forman, J., Hansen, A. E. & Kjær, A., 2016, In: Journal of Nuclear Medicine. 57, 3, p. 437-443 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

In vivo Evaluation of PEGylated ⁶⁴Cu-liposomes with Theranostic and Radiotherapeutic Potential using Micro PET/CT

Petersen, A. L., Henriksen, J. R., Binderup, T., Elema, D. R., Rasmussen, P. H., Hag, A. M., Kjær, A. & Andresen, T. L., 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 5, p. 941-952 12 p.

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2015

Adsorption of Cationic Peptides to Solid Surfaces of Glass and Plastic

Kristensen, K., Henriksen, J. R. & Andresen, T. L., 2015, In: P L o S One. 10, 5, 17 p., e0122419.

Research output: Contribution to journal › Journal article › Research › peer-review

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Allosteric small-molecule kinase inhibitors

Wu, P., Clausen, M. H. & Nielsen, T. E., 2015, In: Pharmacology & Therapeutics. 156, p. 56-68 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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Automated synthesis and PET evaluation of both enantiomers of [18F]FMISO

Revunov, E. V., Jørgensen, J. T., Jensen, A. T. I., Hansen, A. E., Severin, G., Kjær, A. & Zhuravlev, F., 2015, In: Nuclear Medicine and Biology. 42, p. 413–419

Research output: Contribution to journal › Journal article › Research › peer-review

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FDA-approved small-molecule kinase inhibitors

Wu, P., Nielsen, T. E. & Clausen, M. H., 2015, In: Trends in Pharmacological Sciences. 36, 7, p. 422-439 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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In vivo toxicity of cationic micelles and liposomes

Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, J., Jantzen, K., Loft, S., Møller, P. & Roursgaard, M., 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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Quantification and comparison of visibility and image artifacts of a new liquid fiducial marker in a lung phantom for image-guided radiation therapy

Rydhög, J. S., Jølck, R. I., Andresen, T. L. & Munck af Rosenschöld, P., 2015, In: Medical Physics. 42, 6, p. 2818-2826 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Reductive Cyclization and Petasis‐Like Reaction for the Synthesis of Functionalized γ‐Lactams

Wu, P., Petersen, M. Å., Cohrt, A. E., Petersen, R., Clausen, M. H. & Nielsen, T. E., 2015, In: European Journal of Organic Chemistry. 2015, 11, p. 2346-2350 5 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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Remote Loading of ⁶⁴Cu²⁺ into Liposomes without the Use of Ion Transport Enhancers

Henriksen, J. R., Petersen, A. L., Hansen, A. E., Frankær, C. G., Harris, P., Elema, D. R., Kristensen, A. T., Kjær, A. & Andresen, T. L., 2015, In: A C S Applied Materials and Interfaces. 7, 41, p. 22796-22806 11 p.

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Single-vesicle detection and analysis of peptide-induced membrane permeabilization

Kristensen, K., Ehrlich, N., Henriksen, J. R. & Andresen, T. L., 2015, In: Langmuir. 31, 8, p. 2472-2483 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The impact of weakly bound ⁸⁹Zr on preclinical studies: Non-specific accumulation in solid tumors and aspergillus infection

Severin, G., Jørgensen, J. T., Wiehr, S., Rolle, A.-M., Hansen, A. E., Maurer, A., Hasenberg, M., Pichler, B., Kjær, A. & Jensen, A. T. I., 2015, In: Nuclear Medicine and Biology. 42, 4, p. 360–368 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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2014

Acylation of Glucagon-like peptide-2: Interaction with lipid membranes and in vitro intestinal permeability

Trier, S., Linderoth, L., Bjerregaard, S., Andresen, T. L. & Rahbek, U. L., 2014, In: P L o S One. 9, 10, p. e109939 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Lam, H. R. & Lykkesfeldt, J., 2014, In: Journal of Nanoparticle Research. 16, 2, p. 1-11

Research output: Contribution to journal › Journal article › Research › peer-review

Color test for selective detection of secondary amines on resin and in solution.

Boas, U. & Mirsharghi, S., 2014, In: Organic Letters. 16, 22, p. 5918-5921 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cross-linked self-assembled micelle based nanosensor for intracellular pH measurements

Ek, P. K., Søndergaard, R. V., Windschiegl, B., Almdal, K. & Andresen, T. L., 2014, In: Journal of Materials Chemistry B. 2, 38, p. 6652-6659 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Design, calibration and application of broad-range optical nanosensors for determining intracellular pH.

Søndergaard, R. V., Henriksen, J. R. & Andresen, T. L., 2014, In: Nature Protocols. 9, 12, p. 2841-2858

Research output: Contribution to journal › Journal article › Research › peer-review

Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, J., 2014, In: Nanotoxicology. 8, 7, p. 764-774

Research output: Contribution to journal › Journal article › Research › peer-review

Distinct substrate specificities of three glycoside hydrolase family 42 β-galactosidases from Bifidobacterium longum subsp. infantis ATCC 15697

Viborg, A. H., Katayama, T., Abou Hachem, M., Andersen, M. C. F., Nishimoto, M., Clausen, M. H., Urashima, T., Svensson, B. & Kitaoka, M., 2014, In: Glycobiology. 24, 2, p. 208-216

Research output: Contribution to journal › Journal article › Research › peer-review

Effective Nanoparticle-based Gene Delivery by a Protease Triggered Charge Switch

Gjetting, T., Jølck, R. I. & Andresen, T. L., 2014, In: Advanced Healthcare Materials. 3, 7, p. 1107-1118 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Hunde med spontan cancer indgår i translationel forskning

Translated title of the contribution: Canine Cancer Patients are included in translational reseachBørresen, B., Clausen, M. M., Hansen, A. E., Zornhagen, K. W., Kristensen, A. T., Engelholm, S. A. & Kjær, A., 2014, In: Ugeskrift for Laeger. 176, 14, p. 1304-1307 V01130041.

Research output: Contribution to journal › Journal article › Research › peer-review

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Injectable Colloidal Gold in a Sucrose Acetate Isobutyrate Gelating Matrix with Potential Use in Radiation Therapy

Jølck, R. I., Binderup, T., Hansen, A. E., Scherman, J. B., af Rosenschold, P. M., Kjær, A. & Andresen, T. L., 2014, In: Advanced Healthcare Materials. 3, 10, p. 1680-1687

Research output: Contribution to journal › Journal article › Research › peer-review

Positron Emission Tomography Based Analysis of Long-Circulating Cross-Linked Triblock Polymeric Micelles in a U87MG Mouse Xenograft Model and Comparison of DOTA and CB-TE2A as Chelators of Copper-64

Jensen, A. T. I., Binderup, T., Ek, P. K., Kjær, A., Rasmussen, P. & Andresen, T. L., 2014, In: Biomacromolecules. 15, 5, p. 1625–1633

Research output: Contribution to journal › Journal article › Research › peer-review

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Propargylamine-isothiocyanate reaction: efficient conjugation chemistry in aqueous media.

Viart, H.M.-F., Larsen, T. S., Tassone, C., Andresen, T. L. & Clausen, M. H., 2014, In: Chemical Communications. 50, 58, p. 7800-7802

Research output: Contribution to journal › Journal article › Research › peer-review

Quantification of leakage from large unilamellar lipid vesicles by fluorescence correlation spectroscopy

Kristensen, K., Henriksen, J. R. & Andresen, T. L., 2014, In: BBA Biomembranes. 1838, 12, p. 2994-3002

Research output: Contribution to journal › Journal article › Research › peer-review

Side Chain Hydrophobicity Modulates Therapeutic Activity and Membrane Selectivity of Antimicrobial Peptide Mastoparan-X

Henriksen, J. R., Etzerodt, T. P., Gjetting, T. & Andresen, T. L., 2014, In: PLOS ONE. 9, 3, 9 p., e91007.

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Solid-phase synthesis of polyfunctional polylysine dendrons using aldehyde linkers

Svenssen, D. K., Mirsharghi, S. & Boas, U., 2014, In: Tetrahedron Letters. 55, 29, p. 3942-3945 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sucrose acetate isobutyrate based nanogels as liquid fiducial tissue markers with potential use in image guided radiotherapy

Bruun, L. M., Schaarup-Jensen, H., Jølck, R. I., Hansen, A. E., Christiansen, A. N., Clausen, M. H., Kjær, A., Scherman, P. J. B. & Andresen, T. L., 2014. 1 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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Sucrose acetate isobutyrate based nanogels as liquid fiducial tissue markers with potential use in image guided radiotherapy

Bruun, L. M., Schaarup-Jensen, H., Jølck, R. I., Hansen, A. E., Christiansen, A. N., Clausen, M. H., Kjær, A., Scherman, P. J. B. & Andresen, T. L., 2014. 1 p.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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Sucrose acetate isobutyrate-based nanogels as liquid fiducial tissue markers with potential use in image guided radiotherapy

Bruun, L. M., Schaarup-Jensen, H., Jølck, R. I., Hansen, A. E., Christiansen, A. N., Scherman, P. J. B., Clausen, M. H., Kjær, A. & Andresen, T. L., 2014. 1 p.

Research output: Contribution to conference › Poster › Research

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The Chemistry of Griseofulvin

Petersen, A. B., Rønnest, M. H., Larsen, T. O. & Clausen, M. H., 2014, In: Chemical Reviews. 114, 24, p. 12088-12107 20 p.

Research output: Contribution to journal › Journal article › Research › peer-review

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Tomato Cutin Deficient 1 (CD1) and putative orthologs comprise an ancient family of cutin synthase‐like (CUS) proteins that are conserved among land plants

Yeats, T. H., Huang, W., Chatterjee, S., Viart, H.M.-F., Clausen, M. H., Stark, R. E. & Rose, J. K. C., 2014, In: Plant Journal. 77, 5, p. 667-675

Research output: Contribution to journal › Journal article › Research › peer-review

Tracking developmentally regulated post-synthetic processing of homogalacturonan and chitin using reciprocal oligosaccharide probes.

Mravec, J., Kračun, S. K., Rydahl, M. G., Westereng, B., Miart, F., Clausen, M. H., Fangel, J. U., Daugaard, M., Van Cutsem, P., De Fine Licht, H. H., Höfte, H., Malinovsky, F. G., Domozych, D. S. & Willats, W. G. T., 2014, In: Development. 141, 24, p. 4841-4850

Research output: Contribution to journal › Journal article › Research › peer-review

2013

A Mild Method for Regioselective Labeling of Aromatics with Radioactive Iodine

Rønnest, M. H., Nissen, F., Pedersen, P. J., Larsen, T. O., Mier, W. & Clausen, M. H., 2013, In: European Journal of Organic Chemistry. 2013, 19, p. 3970-3973

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Current Challenges and Future Directions in Nanomedicine

Berg, R. H. & Andresen, T. L., 2013, In: JSM Nanotechnology & Nanomedicine. 1, 2

Research output: Contribution to journal › Journal article › Research › peer-review

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Synthesis and Characterization of a Micelle-Based pH Nanosensor with an Unprecedented Broad Measurement Range

Ek, P. K., Feldborg, L. N., Almdal, K. & Andresen, T. L., 2013, In: Chemistry of Materials. 25, 9, p. 1496-1501

Research output: Contribution to journal › Journal article › Research › peer-review

Synthesis of a Backbone Hexasaccharide Fragment of the Pectic Polysaccharide Rhamnogalacturonan I

Zakharova, A. N., Madsen, R. & Clausen, M. H., 2013, In: Organic Letters. 15, 8, p. 201826-1829

Research output: Contribution to journal › Journal article › Research › peer-review

Center for Nanomedicine and Theranostics

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