Description
Attenuation of optical fields owing to scattering and absorption limits the penetration depth into tissue. Whilst aberration correction may be used this is difficult to implement over a large field of view in heterogeneous tissue. Recently, the novel approach of attenuation-compensation of propagation-invariant light fields has shown increase in depth penetration for light-sheet microscopy. Here we show this powerful approach may be implemented in a facile manner utilizing a graded neutral density filter circumventing the need for expensive beam shaping apparatus. A ‘gold standard’ system utilizing a spatial light modulator for beam shaping is used to benchmark our low-cost implementation.| Period | 4 Feb 2020 |
|---|---|
| Event title | SPIE Photonics West 2020: Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVII |
| Event type | Conference |
| Conference number | 11245-17 |
| Location | San Francisco, United States, California |
| Degree of Recognition | International |
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