Characterization of nanoparticles in food using single particle ICP-MS

Activity: Talks and presentationsConference presentations

Description

Nanotechnology and more particularly nanotechnology-based products and materials have a large potential for providing novel solutions to many of the current challenges facing society such as energy supply and resources efficiency, a clean environment, information and communication, mobility and security, and the efficiency of health-related products1. Current applications in the agri/feed/food sector are food additives and food contact materials, whereas potential future developments are expected in the field of nanoencapsulates and nanocomposites in applications such as novel foods, food/feed additives, biocides, pesticides and food contact materials2. With the increasing use of nanotechnology, there is a need for reliable detection and characterization methods for nanoparticles (NPs) in food and biological matrices.

Since a few years, single particle ICP-MS has become increasingly popular and we applied the technique for several samples types including chicken meat (silver NPs), game meat (lead NPs)3, food simulants (silver NPs)4, candy (titanium dioxide NPs) and noodles (aluminum-containing NPs)5. In our experience, single particle ICP-MS is a powerful screening method for the presence of NPs, but an accurate and precise determination of particle size distribution and concentration can be difficult. However, the relatively easy implementation of spICP-MS in state-of-the-art ICP-MS instruments (which can be otherwise used for metal analysis and speciation) makes it a promising technique for routine analysis despite the analytical limitations.

The talk will present general considerations regarding the sample preparation for NPs in food and issues related to calibration and contamination based on selected examples.

The work leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 245162 (NanoLyse) and The Danish Veterinary and Food Administration.

1. Stamm, H., Gibson, N. & Anklam, E. Detection of nanomaterials in food and consumer products: bridging the gap from legislation to enforcement. Food Addit. Contam. Part A 29, 1175–1182 (2012).
2. RIKILT and JRC. Inventory of Nanotechnology applications in the agricultural, feed and food sector. EFSA Support. Publ. EN-621, 1–125 (2014).
3. Kollander, B., Widemo, F., Ågren, E., Larsen, E. H. & Loeschner, K. Detection of lead nanoparticles in game meat by single particle ICP-MS following use of lead-containing bullets. Anal. Bioanal. Chem. 409, 1877–1885 (2017).
4. Jokar, M., Correia, M. & Loeschner, K. Behavior of silver nanoparticles and ions in food simulants and low fat cow milk under migration conditions. Food Control 89, 77–85 (2018).
5. Loeschner, K., Correia, M., López Chaves, C., Rokkjær, I. & Sloth, J. J. Detection and characterisation of aluminium-containing nanoparticles in Chinese noodles by single particle ICP-MS. Food Addit. Contam. Part A 35, 86–93 (2018).

Period2 Nov 2018
Event title6th FFF-MS Workshop: Nanoanalytical Tools in life-science applications - sp-ICP-MS -
Event typeWorkshop
Conference number6
LocationKoblenz, Germany, Rhineland-PalatinateShow on map
Degree of RecognitionInternational